CN216260730U - Disposable biological reaction bag - Google Patents

Disposable biological reaction bag Download PDF

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Publication number
CN216260730U
CN216260730U CN202122387816.2U CN202122387816U CN216260730U CN 216260730 U CN216260730 U CN 216260730U CN 202122387816 U CN202122387816 U CN 202122387816U CN 216260730 U CN216260730 U CN 216260730U
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CN
China
Prior art keywords
inner rotor
sealing structure
bag
bag body
rotor
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Active
Application number
CN202122387816.2U
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Chinese (zh)
Inventor
李智
诸葛鑫
刘金涛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhixiang Biology Suzhou Co ltd
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Zhixiang Biology Suzhou Co ltd
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Priority to CN202122387816.2U priority Critical patent/CN216260730U/en
Application granted granted Critical
Publication of CN216260730U publication Critical patent/CN216260730U/en
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Abstract

The utility model discloses a disposable biological reaction bag, which comprises a bag body, a first inner rotor and a first sealing structure, wherein the first inner rotor and the first sealing structure are arranged at the bottom of the bag body; the top of the bag body is provided with a second sealing structure, the second sealing structure is connected with the bag body in a sealing manner, a second inner rotor is pivoted on the second sealing structure, and the second sealing structure is provided with a second outer rotor matching groove; a stirring shaft is arranged in the bag body, and two ends of the stirring shaft are connected with the first inner rotor and the second inner rotor. The utility model provides a disposable biological reaction bag for a stirring shaft in a reaction bag synchronously driven by an upper motor and a lower motor, and the structural design of the reaction bag provides conditions for the stirring shaft in the reaction bag synchronously driven by the upper motor and the lower motor.

Description

Disposable biological reaction bag
Technical Field
The utility model relates to the technical field of biological pharmacy, in particular to a biological reaction bag.
Background
The disposable biological reaction bag is characterized in that an inner rotor and a sealing structure are arranged at the bottom of a bag body, the sealing structure is connected with the bag body in a sealing mode, the inner rotor is pivoted on the sealing structure and is located in the bag body, and stirring blades are arranged on the inner rotor. And an outer rotor matching groove is arranged on the sealing structure, is positioned outside the bag body and can be matched with the outer rotor, and the outer rotor is connected with the motor.
In actual operation, the disposable biological reaction bag is placed in the steel shell, the bottom of the steel shell is provided with a through hole, and the sealing structure is matched in the through hole. An operator fits the outer rotor into the outer rotor fitting groove, the motor drives the outer rotor to rotate, the magnets in the outer rotor act on the magnets in the inner rotor to drive the inner rotor to rotate, and the stirring blades stir liquid in the reaction bag.
For large disposable bioreactor bags, the mass transfer effect provided by the above stirring is insufficient.
SUMMERY OF THE UTILITY MODEL
The technical problems solved by the utility model are as follows: provides a disposable biological reaction bag capable of improving mass transfer effect.
In order to solve the technical problems, the utility model provides the following technical scheme: the disposable biological reaction bag comprises a bag body, a first inner rotor and a first sealing structure, wherein the first inner rotor and the first sealing structure are arranged at the bottom of the bag body; the top of the bag body is provided with a second sealing structure, the second sealing structure is connected with the bag body in a sealing manner, a second inner rotor is pivoted on the second sealing structure and is positioned in the bag body, the second sealing structure is provided with a second outer rotor matching groove, and the second outer rotor matching groove is positioned outside the bag body; a stirring shaft is arranged in the bag body, and two ends of the stirring shaft are connected with the first inner rotor and the second inner rotor.
The first outer rotor on the first motor shaft is matched into the first outer rotor matching groove, and the second outer rotor on the second motor shaft is matched into the second outer rotor matching groove. The first motor and the second motor rotate synchronously to drive the same stirring shaft to rotate, and the stirring blades on the stirring shaft stir the liquid in the reaction bag. So, can improve the steadiness of (mixing) shaft and the last stirring paddle leaf in the super large reaction bag, conveniently add multilayer stirring vane on the (mixing) shaft, provide better mass transfer effect, solve the contradiction between bulky reaction bag and stirring mass transfer effect are not good.
The utility model provides a disposable biological reaction bag for the stirring shafts in reaction bags driven by a first motor and a second motor up and down synchronously.
Drawings
The utility model is further described below with reference to the accompanying drawings:
FIG. 1 is a schematic view of a disposable bioreactor bag.
The symbols in the drawings illustrate that:
10. a bag body;
20. a first seal structure; 21. a first inner rotor; 210. an inner rotor housing; 211. an inner rotor magnet; 22. a first outer rotor mating groove; 220. a central bore; 23. a first type of stirring blade; 24. the pipeline is arranged on the first sealing structure and used for communicating the bag body with the outside;
30. a second seal structure; 31. a second inner rotor; 32. a second outer rotor mating groove; 33. a limiting groove;
40. a stirring shaft; 41. stirring blades of the second type.
Detailed Description
As shown in fig. 1, the disposable bioreactor bag comprises a bag body 10, a first inner rotor 21 and a first sealing structure 20, wherein the first inner rotor 21 and the first sealing structure 20 are arranged at the bottom of the bag body; the top of the bag body is provided with a second sealing structure 30 which is connected with the bag body in a sealing way, a second inner rotor 31 is pivoted on the second sealing structure and is positioned in the bag body, the second sealing structure is provided with a second outer rotor matching groove 32, and the second outer rotor matching groove is positioned outside the bag body; a stirring shaft 40 is arranged in the bag body, and two ends of the stirring shaft are connected with the first inner rotor and the second inner rotor.
In actual operation, the reaction bag is placed in the steel shell, the outer rotor on the first motor shaft at the bottom of the steel shell is fitted into the first outer rotor fitting groove 22, and the outer rotor on the second motor shaft at the top of the steel shell is fitted into the second outer rotor fitting groove 32. The first motor acts to drive the outer rotor to rotate, and the magnets in the outer rotor act on the magnets of the first inner rotor 21 to drive the first inner rotor to rotate. Likewise, the outer rotor on the second motor shaft drives second inner rotor 31 to rotate. The first motor and the second motor act synchronously to drive the first inner rotor and the second inner rotor to rotate synchronously, and the first inner rotor and the second inner rotor drive the same stirring shaft 40 to rotate.
Any inner rotor comprises an inner rotor shell 210 and an inner rotor magnet 211 sealed in the inner rotor shell, and the stirring shaft 40 is fixedly connected with the inner rotor shell. The stirring shaft is a plastic piece, and the inner rotor shell 210 is a plastic piece, and the two are fixedly connected. The inner rotor is provided with a concave structure, the sealing structure is provided with a convex structure, the bearing is installed on the convex structure, and the bearing is matched in the concave structure, so that the inner rotor is pivoted with the corresponding sealing structure.
The first inner rotor 21 is provided with a first type stirring blade 23, and the stirring shaft 40 is provided with a second type stirring blade 41. The substances in the disposable bioreactor bag are easily sunk by gravity, and thus, the first type of stirring blades can stir and lift the sunk substances to be fully mixed with other substances in the disposable bioreactor bag.
A central hole 220 is arranged in any outer rotor matching groove, and a protruding part capable of being matched with the central hole is arranged on the outer rotor. In actual operation, the outer rotor is matched into the corresponding outer rotor matching groove, and the protruding part is matched with the central hole 220, so that the outer rotor and the corresponding outer rotor matching groove are accurately positioned, and when the outer rotor rotates, the protruding part rotates in the central hole 220, the friction between the outer rotor and the inner wall of the outer rotor matching groove is avoided, and the outer rotor is ensured to rotate smoothly in the outer rotor matching groove.
The second seal structure 30 is provided with a stopper groove 33. In actual operation, the top of the steel shell for placing the reaction bag is open, the reaction bag is placed into the steel shell from the top of the steel shell, the second motor can be installed on a bracket which is installed on the side wall of the steel shell, but the second sealing structure 30 and the second inner rotor 31 at the top of the reaction bag cannot be positioned. Therefore, the second sealing structure of the present invention is provided with a limiting groove 33, which is located outside the reaction bag and at the periphery of the second sealing structure 30. So, connect the clip at box hat top edge and can the centre gripping in spacing groove 33 department, avoid the reaction bag to descend because of gravity, and then the second seal structure 30 at location reaction bag top provides the condition for the cooperation of the outer rotor on the second motor shaft and second outer rotor cooperation groove 32, also provides the condition for the smooth rotation of (mixing) shaft 40.
The above description is only a preferred embodiment of the present invention, and for those skilled in the art, the present invention should not be limited by the description herein, since various changes and modifications can be made in the details of the embodiment and the application range according to the spirit of the present invention.

Claims (5)

1. The disposable biological reaction bag comprises a bag body (10), a first inner rotor (21) and a first sealing structure (20), wherein the first inner rotor (21) and the first sealing structure (20) are arranged at the bottom of the bag body; the method is characterized in that: the top of the bag body is provided with a second sealing structure (30), the second sealing structure is connected with the bag body in a sealing way, a second inner rotor (31) is pivoted on the second sealing structure and is positioned in the bag body, the second sealing structure is provided with a second outer rotor matching groove (32), and the second outer rotor matching groove is positioned outside the bag body; a stirring shaft (40) is arranged in the bag body, and two ends of the stirring shaft are connected with the first inner rotor and the second inner rotor.
2. The disposable bioreactor bag of claim 1, wherein: any inner rotor comprises an inner rotor shell (210) and an inner rotor magnet (211) sealed in the inner rotor shell, and the stirring shaft (40) is fixedly connected with the inner rotor shell.
3. The disposable bioreactor bag of claim 1, wherein: a first type of stirring blade (23) is arranged on the first inner rotor (21), and a second type of stirring blade (41) is arranged on the stirring shaft (40).
4. The disposable bioreactor bag of claim 1, wherein: a central hole (220) is arranged in any outer rotor matching groove.
5. The disposable bioreactor bag of claim 1, wherein: the second sealing structure (30) is provided with a limiting groove (33).
CN202122387816.2U 2021-09-30 2021-09-30 Disposable biological reaction bag Active CN216260730U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202122387816.2U CN216260730U (en) 2021-09-30 2021-09-30 Disposable biological reaction bag

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202122387816.2U CN216260730U (en) 2021-09-30 2021-09-30 Disposable biological reaction bag

Publications (1)

Publication Number Publication Date
CN216260730U true CN216260730U (en) 2022-04-12

Family

ID=81065887

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202122387816.2U Active CN216260730U (en) 2021-09-30 2021-09-30 Disposable biological reaction bag

Country Status (1)

Country Link
CN (1) CN216260730U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115786079A (en) * 2022-12-30 2023-03-14 广州市艾贝泰生物科技有限公司 Biological reaction bag and bioreactor

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115786079A (en) * 2022-12-30 2023-03-14 广州市艾贝泰生物科技有限公司 Biological reaction bag and bioreactor
CN115786079B (en) * 2022-12-30 2024-02-20 广州市艾贝泰生物科技有限公司 Bioreactor bag and bioreactor

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