CN216168049U

CN216168049U - Operation table device

Info

Publication number: CN216168049U
Application number: CN202121491735.0U
Authority: CN
Inventors: 尹琳琳; 苌浩晓; 张星虎; 王玉鹏; 丛衡日; 魏玉桢; 徐芸
Original assignee: Beijing Tiantan Hospital
Current assignee: Beijing Tiantan Hospital
Priority date: 2021-07-02
Filing date: 2021-07-02
Publication date: 2022-04-05
Anticipated expiration: 2031-07-02

Abstract

The utility model discloses an operation table device, comprising: an operation table base and an operation table top; the adjustable rod is positioned between the operating platform base and the operating platform surface and is respectively connected with the operating platform base and the operating platform surface, the inclined operating surface is positioned on the operating platform and is used for fixing and supporting an operating object, and the head fixing and angle adjusting component is adjacent to the inclined operating surface and is used for adjusting the angle between the head and the trunk of the operating object. The operation table device can reduce the operation difficulty of the operation, obviously improve the success rate of operations such as intrathecal intubation and the like and the survival rate of mice, and has important significance for researching central nervous system diseases.

Description

Operation table device

Technical Field

The utility model relates to the technical field of experimental equipment, in particular to an operating table device for intrathecal intubation or drug delivery of animals (such as mice).

Background

Animal experiments are an important link and link from molecular cell level to clinical research for scientific research, and are common experimental tools for researching disease pathogenesis and drug efficacy. The blood brain barrier is a natural barrier of the central nervous system, and the selective permeability of the blood brain barrier plays an important role and has biological significance in maintaining the independent and stable environment in brain and spinal cord tissues. But also brings great challenges to the construction of experimental animal models simulating central nervous system disease damage, the research of drugs which are water-soluble, macromolecular and the like and are difficult to penetrate through a blood brain barrier and act on the central nervous system.

The cerebrospinal fluid examination can directly reflect the pathological change process of the central nervous system diseases, has high sensitivity and high specificity, and has important significance for researching the central nervous system diseases. In view of the restriction of the body types of some animals (such as mice), the cerebrospinal fluid content is low, the difficulty in obtaining the cerebrospinal fluid is high, the mortality rate is high, the acquisition of the cerebrospinal fluid sample of the mice is severely restricted, and the related research development is not facilitated.

In certain human diseases, peripheral free pathogenic agents cross the blood-brain barrier or are damaged by attack on the blood-brain barrier, leading to pathological damage of the central nervous system. Based on the limited understanding of the pathogenesis of the current diseases, the constructed disease animal model cannot act on the craniocerebra or the spinal cord to simulate the pathological injury of the central nervous system because the transmission of pathogenic factors or the process of changing the permeability of the blood brain barrier is difficult to simulate, thereby greatly restricting the research of related diseases.

In view of the different blood brain barrier permeability of drugs, peripheral administration modes such as intravenous injection are difficult to achieve effective therapeutic concentrations in cerebrospinal fluid or brain tissue. The candidate drug or the modeling reagent is directly delivered to the corresponding part of the central nervous system to evaluate the curative effect of the drug or prepare the central nervous injury experimental animal model, and has important value for screening the valuable compound of the targeted central nervous system or researching the disease animal model.

Disclosure of Invention

In view of the blind spots of the prior art, the present invention is designed to provide a console device that can be used for intrathecal intubation or drug administration procedures on animals (e.g., mice).

Specifically, the utility model provides the following technical scheme:

an operation panel device comprising:

a base (1) of the operating platform,

an operation table top (3);

an adjustable rod (2) which is arranged between the operating platform base (1) and the operating platform surface (3) and is respectively connected with the operating platform base (1) and the operating platform surface (3),

an inclined operating surface (4) on the operating floor (3) for fixing and supporting an operating object, and

and the head fixing and angle adjusting component (5) is arranged adjacent to the inclined operation surface (4) and is used for adjusting the angle between the head and the trunk of the operation object.

Preferably, the adjustable rod is vertically welded with the operating platform base.

Preferably, the adjustable rod is movably connected with the operation table top, so that the distance between the operation table top and the operation table base is adjusted within the range of 5-15 cm.

Preferably, the adjustable rod is movably connected with the operation table top, so that the angle of the operation table top relative to the adjustable rod is adjusted within the range of 60-120 degrees.

Preferably, the inclined operating face is angled at an angle of 30-45 ° to the operating deck.

Preferably, the head fixation and angle adjustment assembly positions the subject's head at 115 and 125 ° from the torso.

Preferably, the head fixing and angle adjusting assembly comprises a head fixing ferrule and a ferrule connecting rod, wherein the connecting rod is fixed on the operation table top.

Preferably, the inclined operating surface is fixed on the operating table top.

Preferably, the adjustment assembly is fixed on the operation table.

Preferably, the dimensions of the worktop are 25cm in length by 20cm in width by 0.5cm in thickness.

The operating table device of the utility model has scientific structure and reasonable design, and solves the technical problem of intrathecal administration or intrathecal intubation of animals (such as mice). The operation table can be applied to, but not limited to, animal cerebrospinal fluid acquisition, central nervous system administration, central nervous injury experimental animal model preparation and the like. The operation console provides important support for the operation of the animal intrathecal intubation, obviously reduces the operation difficulty, and obviously improves the success rate of the operation of the intrathecal intubation and the survival rate of animals. Has important significance for the research of central nervous system diseases through blood brain barrier and intrathecal administration. The device can be applied to other animal experiments directly acting on the central nervous system, and has the advantages of strong universality, convenient and quick operation and good fixing effect.

Brief description of the drawings

Exemplary embodiments of the utility model are described in detail based on the following figures, wherein:

FIG. 1 is a schematic view showing the overall structure of a console device according to an example of the present invention;

FIG. 2 is a diagram showing the completion of an intrathecal intubation procedure for mice in accordance with an embodiment of the present invention.

FIG. 3 is a cross-sectional view of a head fixation and angle adjustment assembly of one example of the present invention.

Detailed Description

Exemplary embodiments of the present invention are described below with reference to the accompanying drawings. It is to be understood that the description is intended to be illustrative of the utility model and not to be limiting, and that the description is intended to teach one skilled in the art how to practice the utility model, and is not intended to be exhaustive or to limit the scope of the utility model.

As shown in fig. 1, the present invention provides an operation table device including: the operation table comprises an operation table base 1, an operation table top 3, an adjustable rod 2 which is arranged between the operation table base and the operation table top and is respectively connected with the operation table base and the operation table top, an inclined operation surface 4 which is arranged on the operation table and a head fixing and angle adjusting component 5 which is arranged adjacent to the inclined operation surface. The inclined operation surface 4 is used to fix and support an operation object. The head fixing and angle adjusting unit 5 adjacent to the inclined operation surface is used to adjust the angle between the head and the trunk of the operation subject.

In one example, the console device is a mouse intrathecal intubation console device. In one example, the console base of the console device of the mouse intrathecal cannula is dimensioned to have a length of 30cm x, a width of 25cm x and a thickness of 0.5 cm.

In one example, the base of the console is made of stainless steel.

In one example, the adjustable bar 2 is welded to the console base 1 vertically.

In one example, the adjustable lever 2 can adjust the distance between the console base 1 and the console top 3 in a range of 5-15 cm.

In one example, the angle adjustment range of the operation table 3 and the adjustable rod 2 is: 60-120 degrees.

In one example, the dimensions of the worktop 3 are 25cm in length by 20cm in width by 0.5cm in thickness.

In one example, the material of the operation table 3 is stainless steel.

In one example, the inclined operating surface 4 is fixed to the operating floor.

In one example, the inclined operating surface 4 is made of wood.

In one example, the head-fixing and angle-adjusting assembly 5 is fixed to the operating table top 3. In a preferred example, referring to fig. 3, the head fixing and angle adjusting assembly includes a head fixing ferrule 51 and a ferrule connecting rod 53, wherein the connecting rod can be fixed to the operating table by a fixing member 52 and the angle of the ferrule is adjusted.

In one embodiment: as shown in fig. 1, the console device is a console device for mouse intrathecal intubation surgery, and includes a surgical console base, an adjustable rod, a console top, a mouse support and fixation inclined console surface, and a head fixation and angle adjustment assembly. Wherein, the size of the base of the operation table is larger than that of the operation table surface, and the whole operation table device is fixed and supported.

In a second embodiment, as shown in fig. 1, the adjustable rod of the mouse intrathecal surgical console apparatus is used to adjust the relative distance between the surgical console base and the operating table top and is fixed with a knob.

In a third embodiment: as shown in figure 1, the angle between the operation table surface and the adjustable rod of the operation table device for mouse intrathecal intubation can be freely adjusted within the range of 60-120 degrees, thereby meeting the requirements of different operation application scenes.

In a fourth embodiment: the mouse is placed on the operation table-board after being anesthetized, and the angles of the adjusting rod and the operation table-board are adjusted, so that the operation of an operator is facilitated. Depilating and skin preparation are started from the head along the binaural line to the trunk. After the skin preparation, the mouse is placed on the supporting and fixing slope, and the head of the mouse is pushed into the head fixing and angle adjusting assembly, so that the head and the trunk of the mouse form a specific angle. The skin is cut open and separated and the catheter is inserted from the cisterna bulbosus. FIG. 2 is a representation of the completion of an example of intrathecal intubation in mice.

The operating principle of the operating platform device of the utility model is as follows: the head of the operation head portrait is at a specific angle with the trunk by fixing the adjusting component of the head of the operation head portrait, cerebrospinal fluid can be obtained from the medullary oblongata pool by using a capillary glass tube or other catheters, and the soft catheter can be further inserted into the cavity of the spinal cord and the spinal column from the medullary oblongata pool, so that the requirement of conveying carriers such as medicaments to a central nervous system is met.

The present invention is not limited to the above-described embodiments, and those skilled in the art can make various modifications to the above-described embodiments of the present invention without departing from the scope of the present invention in light of the above teachings.

Claims

1. An operation panel device characterized by comprising:

a base (1) of the operating platform,

an operation table top (3);

and the head fixing and angle adjusting assembly (5) is arranged adjacent to the inclined operation surface (4) and is used for adjusting the angle between the head and the trunk of the operation object, so that the head and the trunk of the operation object form an angle of 115 degrees and 125 degrees.

2. Operator station device according to claim 1, characterized in that the adjustable bar (2) is welded perpendicularly to the operator station base (1).

3. Operator station arrangement according to claim 1 or 2, characterized in that the adjustable bar (2) is movably connected to the operator station top (3) such that the distance between the operator station top (3) and the operator station base (1) is adjusted in the range of 5-15 cm.

4. Operator station arrangement according to any of the claims 1-3, characterized in that the adjustable bar (2) is movably connected to the operator station top (3) such that the angle of the operator station top with respect to the adjustable bar (2) is adjusted in the range of 60-120 °.

5. Operator station arrangement according to any of the claims 1-4, characterized in that the inclined operator plane (4) forms an angle of 30-45 ° with the operator table top (3).

6. Station arrangement according to any of claims 1-5, characterized in that the head fixation and angle adjustment assembly comprises a head fixation ferrule and a ferrule connection rod, wherein the connection rod is fixed to the station surface (3).

7. Operator station arrangement according to any of the claims 1-6, characterized in that the inclined operator plane (4) is fixed to the operator station top.

8. Operator station arrangement according to any of the claims 1-7, characterized in that the adjustment assembly (5) is fixed to the operator station top (3).

9. Console device according to any of claims 1-8, characterized in that the dimensions of the console top are 25cm in length x 20cm in width x 0.5cm in thickness.