CN216155831U

CN216155831U - Continuous heat seal film machine of deep hole board is drawed to bulky nucleic acid

Info

Publication number: CN216155831U
Application number: CN202122191831.XU
Authority: CN
Inventors: 王军; 赵冰琳; 陈天; 刘子璇; 李蕾; 吕舒瑶; 郑浩; 李钰; 韩少宇; 任乐峰; 李龙; 周建中; 高岩; 李亚蒙; 袁世清; 王路怡; 樊锦轲; 袁现发; 张宝宝
Original assignee: Zhengzhou Zhijie Biotechnology Co ltd
Current assignee: Zhengzhou Zhijie Biotechnology Co ltd
Priority date: 2021-09-10
Filing date: 2021-09-10
Publication date: 2022-04-01
Anticipated expiration: 2031-09-10

Abstract

The utility model discloses a large-volume nucleic acid extraction deep-hole plate continuous heat sealing film machine, relates to the technical field of nucleic acid extraction, and particularly comprises a bottom plate, wherein the top of the bottom plate is fixedly connected with a conveying belt and a heat sealing film machine respectively, and the top of the conveying belt is fixedly connected with a square box. This continuous heat seal membrane machine of deep hole board is drawed to bulky nucleic acid, through the regulating block, electronic hydraulic push rod, the elevator, protruding type piece, the slider, the cooperation piece, the setting of clamp splice and trapezoidal piece, make this continuous heat seal membrane machine of deep hole board drawed of bulky nucleic acid possess the effect of the position of convenient restriction deep hole board, the in-process cooperation piece that uses drives the clamp splice and removes, make the position of clamp splice restriction deep space board, the slider plays the effect that the location removed, the conveyer belt, first correlation inductor and the convenient conveying deep hole board of second correlation inductor, make things convenient for the continuous membrane of heat seal membrane machine, thereby the effect of the position of convenient restriction deep hole board has been played, the purpose of the position of convenient restriction deep hole board has been reached.

Description

Continuous heat seal film machine of deep hole board is drawed to bulky nucleic acid

Technical Field

The utility model relates to the technical field of nucleic acid extraction, in particular to a large-volume nucleic acid extraction deep-hole plate continuous heat film sealing machine.

Background

At present, on the basis of the appearance size of a common microporous plate (mainly a 96-384 microporous plate), the depth of each pore is increased while the length and the width of each pore are kept in accordance with the SBS international specification, so that the purpose of increasing the volume of each pore is achieved. And in order to adapt to the specific application range, the laboratory plate is manufactured by changing the manufacturing materials (currently, polypropylene (PP) is used frequently and Polystyrene (PS) is used individually) and improving the surface treatment process; the method is classified according to the number of the holes, and the common method can be divided into a 96-hole plate and a 384-hole plate; the 96-well plates are classified by well type, and are mainly classified into circular well type and square well type. Wherein, the 384 pore plates are all square pore type; the method is classified according to the shape of the bottom of the hole, and the U-shaped and the V-shaped are common. The application range of the deep hole plate is as follows: storing the sample: can replace the conventional 1.5ml centrifuge tube to store samples, and the storage is neat in placement, saves space, has large storage capacity and can tolerate a refrigerator at minus 80 ℃. Therefore, it is also called storage block; treating a sample: the high-throughput operation of biological samples, such as protein precipitation and liquid-liquid extraction, can be realized by combining a discharging gun, a high-throughput automatic liquid operation instrument and software. Greatly improving the efficiency of sample treatment. The PP material can better resist the high-temperature and high-pressure sterilization treatment at 121 ℃; sample introduction operation: the automatic sample injector is universal for various automatic sample injectors, can be directly placed in a sample bin of the automatic sample injector for sample injection, and compared with a traditional sample injection small bottle, the sample injection device not only can multiply the number of samples in the sample bin, but also can realize direct sample injection after the samples are processed on a 96-hole plate, thereby omitting complex work of back-and-forth sample absorption, sample placement, cover covering, insertion and insertion of a cannula, bottle washing and the like.

At present, the position of a deep hole plate is inconveniently limited when a film is sealed by a heat sealing film machine in the prior art, the sealing performance of the sealed film is poor easily caused by the movement of the deep hole plate, and the deviation of the film sealing position is easily caused by the inconvenience of adjusting the position of the deep hole plate after the deep hole plate is placed, so that the film sealing efficiency is poor.

SUMMERY OF THE UTILITY MODEL

Technical problem to be solved

Aiming at the defects of the prior art, the utility model provides a large-volume nucleic acid extraction deep hole plate continuous heat film sealing machine, which solves the problems in the background technology.

(II) technical scheme

In order to achieve the purpose, the utility model is realized by the following technical scheme: a continuous heat sealing film machine of a large-volume nucleic acid extraction deep hole plate comprises a bottom plate, wherein the top of the bottom plate is fixedly connected with a conveyor belt and a heat sealing film machine respectively, the top of the conveyor belt is fixedly connected with a square box, the inner side wall of the square box is fixedly connected with a storage battery and a servo motor respectively, the output end of the servo motor is fixedly connected with a threaded rod, the outer surface of the threaded rod which is patted is in threaded connection with a moving block, the top of the moving block is fixedly connected with an adjusting block, the inside of the adjusting block is provided with an adjusting groove and a sliding groove respectively, the inside of the adjusting groove is fixedly connected with an electric hydraulic push rod, the movable end of the electric hydraulic push rod is fixedly connected with a lifting block, the two side surfaces of the lifting block are fixedly connected with convex blocks, the inside of the sliding groove is slidably connected with a sliding block, one side surface of the sliding block is fixedly connected with a matching block, and the top of the matching block is fixedly connected with a clamping block, the bottom of the matching block is fixedly connected with a trapezoidal block.

Optionally, a positioning groove is formed in the moving block, a positioning rod is arranged in the positioning groove, a limiting block is fixedly connected to the outer surface of the positioning rod, the diameter of the limiting block is larger than that of the positioning groove, and two ends of the positioning rod are fixedly connected with the inner side wall of the square box.

Optionally, one end of the threaded rod, which is far away from the servo motor, is rotatably connected with the inner side wall of the square box through a bearing, and the end part of the moving block is located inside the square box.

Optionally, a convex groove is formed on the inclined surface of the trapezoidal block, and the convex block is slidably connected inside the convex groove.

Optionally, a first correlation inductor is arranged on one side surface of the square box, a second correlation inductor is arranged on one side surface of the heat film sealing machine, and the position of the first correlation inductor corresponds to the position of the second correlation inductor.

Optionally, the storage battery is respectively electrically connected with the servo motor, the electric hydraulic push rod and the first correlation inductor through leads, and the conveyor belt, the heat sealing film machine and the second correlation inductor are electrically connected with an external power supply through leads.

(III) advantageous effects

The utility model provides a large-volume nucleic acid extraction deep-hole plate continuous heat sealing film machine, which has the following beneficial effects:

1. this continuous heat seal membrane machine of deep hole board is drawed to bulky nucleic acid, through the regulating block, electronic hydraulic push rod, the elevator, protruding type piece, the slider, the cooperation piece, the setting of clamp splice and trapezoidal piece, make this continuous heat seal membrane machine of deep hole board drawed of bulky nucleic acid possess the effect of the position of convenient restriction deep hole board, the in-process cooperation piece that uses drives the clamp splice and removes, make the position of clamp splice restriction deep space board, the slider plays the effect that the location removed, the conveyer belt, first correlation inductor and the convenient conveying deep hole board of second correlation inductor, make things convenient for the continuous membrane of heat seal membrane machine, thereby the effect of the position of convenient restriction deep hole board has been played, the purpose of the position of convenient restriction deep hole board has been reached.

2. This bulky nucleic acid draws continuous heat seal membrane machine of deep hole board, through servo motor, the threaded rod, the movable block, the setting of locating lever and stopper, make this bulky nucleic acid draw continuous heat seal membrane machine of deep hole board possess the position of conveniently adjusting the deep hole board, improve the effect of the precision of sealing the membrane, the in-process movable block that uses removes on the threaded rod, adjusting position, the locating lever plays the effect of location, the extreme position that the stopper restriction movable block removed, avoid the movable block to touch the battery, thereby the effect of conveniently adjusting the deep hole board has been played, the purpose of the precision of sealing the membrane has been reached.

Drawings

FIG. 1 is a schematic perspective view of the present invention;

FIG. 2 is a schematic structural diagram of a front view cross section of the present invention;

FIG. 3 is a schematic top view of the present invention;

FIG. 4 is an enlarged schematic view of FIG. 3 at A according to the present invention;

FIG. 5 is a schematic side view of the present invention;

FIG. 6 is an enlarged view of the structure of FIG. 5B according to the present invention.

In the figure: 1. a base plate; 2. a conveyor belt; 3. a film heat sealing machine; 4. a square frame box; 5. a storage battery; 6. a servo motor; 7. a threaded rod; 8. a moving block; 9. an adjusting block; 10. an electric hydraulic push rod; 11. a lifting block; 12. a convex block; 13. a slider; 14. a matching block; 15. a clamping block; 16. a trapezoidal block; 17. positioning a rod; 18. a limiting block; 19. a first correlation sensor; 20. a second correlation sensor.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.

Referring to fig. 1 to 6, the present invention provides a technical solution: a continuous heat sealing film machine of a deep hole plate for extracting large-volume nucleic acid comprises a bottom plate 1, wherein the top of the bottom plate 1 is fixedly connected with a conveyor belt 2 and a heat sealing film machine 3 respectively, the top of the conveyor belt 2 is fixedly connected with a square box 4, one side surface of the square box 4 is provided with a first correlation inductor 19, one side surface of the heat sealing film machine 3 is provided with a second correlation inductor 20, the position of the first correlation inductor 19 corresponds to the position of the second correlation inductor 20, the inner side wall of the square box 4 is fixedly connected with a storage battery 5 and a servo motor 6 respectively, through the arrangement of the servo motor 6, a threaded rod 7, a movable block 8, a positioning rod 17 and a limiting block 18, the continuous heat sealing film machine of the deep hole plate for extracting large-volume nucleic acid has the effect of conveniently adjusting the position of the deep hole plate and improving the precision of film sealing, the movable block 8 moves on the threaded rod 7 in the using process to adjust the position, the positioning rod 17 plays a role in positioning, the limiting block 18 limits the limit position of the movement of the moving block 8, the moving block 8 is prevented from touching the storage battery 5, and therefore the effect of conveniently adjusting the deep hole plate is achieved, and the purpose of improving the film sealing accuracy is achieved, the storage battery 5 is respectively and electrically connected with the servo motor 6, the electric hydraulic push rod 10 and the first correlation inductor 19 through leads, the conveyor belt 2, the heat sealing film machine 3 and the second correlation inductor 20 are electrically connected with an external power supply through leads, the output end of the servo motor 6 is fixedly connected with the threaded rod 7, one end of the threaded rod 7 far away from the servo motor 6 is rotatably connected with the inner side wall of the square box 4 through a bearing, the end part of the moving block 8 is positioned inside the square box 4, the outer surface of the clapped threaded rod 7 is in threaded connection with the moving block 8, the positioning groove is formed in the moving block 8, and the positioning rod 17 is arranged inside the positioning groove, the outer surface of the positioning rod 17 is fixedly connected with a limiting block 18, the diameter of the limiting block 18 is larger than that of the positioning groove, two ends of the positioning rod 17 are fixedly connected with the inner side wall of the square box 4, the top of the moving block 8 is fixedly connected with an adjusting block 9, the electric hydraulic push rod 10, the lifting block 11, the convex block 12, the sliding block 13, the matching block 14, the clamping block 15 and the trapezoidal block 16 are arranged, so that the large-volume nucleic acid extraction deep hole plate continuous heat sealing film machine has the effect of conveniently limiting the position of the deep hole plate, the matching block 14 drives the clamping block 15 to move in the use process, the clamping block 15 limits the position of the deep hole plate, the sliding block 13 plays a role in positioning and moving, the conveyor belt 2, the first correlation inductor 19 and the second correlation inductor 20 are convenient for conveying the deep hole plate, and the heat sealing film machine 3 is convenient for continuously sealing the film, thereby playing a role in conveniently limiting the position of the deep hole plate, the purpose of the position of convenient restriction deep hole board has been reached, adjustment tank and spout have been seted up respectively to the inside of regulating block 9, the inside fixedly connected with electric hydraulic rod 10 of adjustment tank, the expansion end fixedly connected with elevator 11 of electric hydraulic rod 10, the equal fixedly connected with convex block 12 of both sides face of elevator 11, the inside sliding connection of spout has slider 13, a side fixedly connected with cooperation piece 14 of slider 13, the top fixedly connected with clamp splice 15 of cooperation piece 14, the bottom fixedly connected with trapezoidal block 16 of cooperation piece 14, convex groove has been seted up on trapezoidal block 16's inclined plane, convex block 12 sliding connection is in the inside in convex groove.

When the device is used, a deep hole plate needing film sealing is placed on the adjusting block 9, the storage battery 5 supplies electricity to the servo motor 6, the electric hydraulic push rod 10 and the first correlation inductor 19, the electric hydraulic push rod 10 retracts movably, the lifting block 11 moves downwards, the convex block 12 moves in the convex groove, force in the horizontal direction is supplied to the trapezoidal block 16, the trapezoidal block 16 moves, the sliding block 13 moves in the sliding groove in a positioning mode, the clamping block 15 limits the position of the deep hole plate, the conveying belt 2 conveys the deep hole plate, when the first correlation inductor 19 and the second correlation inductor 20 perform correlation, the conveying belt 2 stops rotating, film sealing is performed through the heat-sealing film machine 3, the conveying belt 2 continues conveying after film sealing, the next deep hole plate is convenient to seal, when a certain deviation exists between the position where the deep hole plate is placed and the position where the heat-sealing film machine 3 exists, the servo motor 6 drives the threaded rod 7 to rotate, make the movable block 8 remove on threaded rod 7, locating lever 17 runs through in the constant head tank and plays the positioning action, and stopper 18 limits the extreme position of movable block 8, avoids movable block 8 to touch battery 5, and the convenient position of adjusting the deep hole board in certain extent makes things convenient for heat seal film machine 3 to seal the membrane.

In conclusion, the utility model enables the continuous heat sealing film machine for extracting the deep hole plate from the large-volume nucleic acid to have the effect of conveniently limiting the position of the deep hole plate by arranging the adjusting block 9, the electric hydraulic push rod 10, the lifting block 11, the convex block 12, the sliding block 13, the matching block 14, the clamping block 15 and the trapezoidal block 16, the matching block 14 drives the clamping block 15 to move in the use process, the clamping block 15 limits the position of the deep hole plate, the sliding block 13 plays a role of positioning and moving, the conveying belt 2, the first opposite-jet inductor 19 and the second opposite-jet inductor 20 conveniently convey the deep hole plate and conveniently and the heat sealing film machine 3 continuously seals the film, so that the function of conveniently limiting the position of the deep hole plate is achieved, the purpose of conveniently limiting the position of the deep hole plate is achieved, the continuous heat sealing film machine for extracting the deep hole plate from the large-volume nucleic acid has the effect of conveniently adjusting the position of the deep hole plate by arranging the servo motor 6, the threaded rod 7, the moving block 8, the positioning rod 17 and the limiting block 18, the effect of the precision of the film is sealed is improved, the moving block 8 moves on the threaded rod 7 in the using process, the position is adjusted, the positioning rod 17 plays a role in positioning, the limiting block 18 limits the limit position of the moving block 8 in moving, the moving block 8 is prevented from touching the storage battery 5, the effect of conveniently adjusting the deep hole plate is achieved, and the purpose of improving the precision of the film sealing is achieved.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and equivalent alternatives or modifications according to the technical solution of the present invention and the inventive concept thereof should be covered by the scope of the present invention.

Claims

1. The utility model provides a continuous heat seal membrane machine of big volume nucleic acid extraction deep hole board, includes bottom plate (1), its characterized in that: the top of the bottom plate (1) is fixedly connected with a conveyor belt (2) and a heat-sealing film machine (3) respectively, the top of the conveyor belt (2) is fixedly connected with a square frame box (4), the inner side wall of the square frame box (4) is fixedly connected with a storage battery (5) and a servo motor (6) respectively, the output end of the servo motor (6) is fixedly connected with a threaded rod (7), the outer surface of the shot threaded rod (7) is connected with a movable block (8) in a threaded manner, the top of the movable block (8) is fixedly connected with an adjusting block (9), the inside of the adjusting block (9) is provided with an adjusting groove and a sliding groove respectively, the inside of the adjusting groove is fixedly connected with an electric hydraulic push rod (10), the movable end of the electric hydraulic push rod (10) is fixedly connected with a lifting block (11), and the two side faces of the lifting block (11) are both fixedly connected with convex blocks (12), the inside sliding connection of spout has slider (13), a side fixedly connected with cooperation piece (14) of slider (13), the top fixedly connected with clamp splice (15) of cooperation piece (14), the bottom fixedly connected with trapezoidal piece (16) of cooperation piece (14).

2. The large-volume nucleic acid extraction deep-hole plate continuous heat film sealing machine according to claim 1, characterized in that: the positioning groove is formed in the moving block (8), the positioning rod (17) is arranged in the positioning groove, the outer surface of the positioning rod (17) is fixedly connected with a limiting block (18), the diameter of the limiting block (18) is larger than that of the positioning groove, and two ends of the positioning rod (17) are fixedly connected with the inner side wall of the square box (4).

3. The large-volume nucleic acid extraction deep-hole plate continuous heat film sealing machine according to claim 1, characterized in that: one end, far away from the servo motor (6), of the threaded rod (7) is rotatably connected with the inner side wall of the square box (4) through a bearing, and the end part of the moving block (8) is located inside the square box (4).

4. The large-volume nucleic acid extraction deep-hole plate continuous heat film sealing machine according to claim 1, characterized in that: the inclined plane of trapezoidal piece (16) has seted up protruding type groove, protruding type piece (12) sliding connection is in the inside in protruding type groove.

5. The large-volume nucleic acid extraction deep-hole plate continuous heat film sealing machine according to claim 1, characterized in that: a first correlation inductor (19) is arranged on one side face of the square box (4), a second correlation inductor (20) is arranged on one side face of the heat film sealing machine (3), and the position of the first correlation inductor (19) corresponds to the position of the second correlation inductor (20).

6. The large-volume nucleic acid extraction deep-hole plate continuous heat film sealing machine according to claim 5, characterized in that: the storage battery (5) is electrically connected with the servo motor (6), the electric hydraulic push rod (10) and the first correlation sensor (19) through leads, and the conveyor belt (2), the heat-sealing film machine (3) and the second correlation sensor (20) are electrically connected with an external power supply through leads.