CN216124875U - Article surface coronavirus disinfection device capable of inducing spike protein S denaturation - Google Patents
Article surface coronavirus disinfection device capable of inducing spike protein S denaturation Download PDFInfo
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- CN216124875U CN216124875U CN202121882711.8U CN202121882711U CN216124875U CN 216124875 U CN216124875 U CN 216124875U CN 202121882711 U CN202121882711 U CN 202121882711U CN 216124875 U CN216124875 U CN 216124875U
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Abstract
The utility model discloses a device for disinfecting coronavirus on the surface of an article by inducing the denaturation of spike protein S, which is characterized in that after the article is conveyed by a conveying line and corrected by a propelling device, a first disinfection area at the upper part of the conveying line disinfects the front, the upper and the rear of the article, a second disinfection area disinfects the left and the right of the article, and a third disinfection area disinfects the lower part of the article, so that the purpose of disinfecting viruses is achieved.
Description
Technical Field
The utility model relates to the technical field of coronavirus disinfection, in particular to an article surface coronavirus disinfection device for inducing spike protein S denaturation.
Background
At present, the technical scheme for chemically killing coronavirus does not clearly provide a specific target site for killing coronavirus particles, and the disinfectant used lacks a detailed description of a virus killing mechanism, so that effective coronavirus killing guidance cannot be obtained. Meanwhile, the chemical disinfectant has obvious pollution, so that the application range is limited. Also, the chemical sterilizing apparatus requires a special use environment. The open type chemical disinfection method generally adopts a spraying or wiping method, most of water-based disinfectants can only keep moisture on the surface of an article for 1-4 min, and the action time is short. The utility model does not have the efficient, quick and chemical pollution-free function of killing the coronavirus on the surface of the article, which is widely applicable.
The utility model discloses a chinese utility model patent that publication number is CN211724143U discloses an air sterilization disinfection system, including the clean room, be equipped with the air in the clean room and absorb the district, multistage air purification district and exhaust area, wherein, the air is absorbed the district and is located the clean room both ends respectively with the district of airing exhaust, and the air is absorbed the district and is included wind-guiding mouth and turbofan, and the air is absorbed the district and is equipped with multistage air purification district between the district of airing exhaust, and multistage air purification district includes one-level physics filtering area and one-level electric field absorption purifying area at least, and physics filtering area is located the upper reaches of electric field absorption purifying area. This air sterilization and disinfection system sets up multistage air purification district in the clean room, adopts the mode that ultraviolet sterilization, high-voltage static sterilization combined together, effectively gets rid of microorganisms such as virus, bacterium in the air, improves the air purification effect. And the vehicle-mounted tank can be adopted, so that the vehicle-mounted tank can be conveniently opened to an epidemic situation area, and large-area air sterilization and disinfection can be carried out to kill infectious viruses such as novel coronavirus and the like. The air sterilization and disinfection system is suitable for killing bacteria in the air, and the killing principle of coronavirus on the surface of an article is not disclosed.
The Chinese patent with publication number CN111940143A discloses a sterilizing, disinfecting and ozone-removing electrostatic adsorption electrode and a preparation method thereof, comprising an electrostatic dust collection electrode and a discharge electrode which are matched for use; the electrostatic precipitation electrode includes: the surface of the electrostatic dust collection electrode plate is coated with metal particles, and a disinfecting and sterilizing metal particle coating is formed on the surface of the electrostatic dust collection electrode plate; the discharge electrode includes: the surface of the discharge electrode plate is coated with an ozone decomposition catalyst, and an ozone decomposition catalyst coating is formed on the surface of the discharge electrode plate; the electrode can continuously, efficiently and thoroughly kill microorganisms such as broad-spectrum bacteria, viruses and the like in the air under the condition of people, and particularly has important application in the aspect of new coronavirus. The sterilization, disinfection and ozone removal adsorption electrode provided by the utility model can be used for thoroughly and efficiently killing harmful microorganisms in air under continuous conditions, and does not have the function of killing coronavirus on the surface of an article.
Disclosure of Invention
The utility model mainly aims to overcome the defects in the technology, and provides the device for disinfecting the coronavirus on the surface of the article by inducing the denaturation of the spike protein S, which has the function of killing the coronavirus on the surface of the article and widens the application range of the electric field technology for killing the coronavirus.
In order to overcome the technical problems, the utility model adopts the technical scheme that:
a device for sterilizing coronavirus on the surface of an article for inducing the denaturation of spike protein S is characterized in that the article is conveyed by a conveying line and corrected by a propelling device, the front, the upper and the rear of the article are sterilized by a first sterilizing area arranged at the upper part of the conveying line, the article is conveyed by the conveying line to a second sterilizing area for sterilizing the left and the right of the article, and then the article is conveyed by the conveying line to a third sterilizing area for sterilizing the lower part of the article;
the conveying line comprises a frame body, a third killing area arranged at the joint of the rear end of the frame body, conveying belt devices respectively arranged in the upper end plane of the frame body, a second killing area arranged on the frame body and a propelling device arranged on the frame body;
the frame body comprises a frame body for arranging the conveying line in the frame body, a small frame body arranged at the rear end of the frame body and arranging the third killing area in the frame body, supporting legs which are respectively arranged on the lower end surfaces of the front end and the rear end of the frame body and are used for supporting the ground, a first workbench which is arranged behind the supporting legs at the front end of the frame body and is connected with the lower end surface of the frame body, a second workbench which is connected with the lower end surface of the frame body and is arranged behind the first workbench, a gantry frame which is arranged on the upper end surface of the frame body and corresponds to the second workbench in position, a first fixing frame which is close to the front end of the frame body and is arranged at the left end of the upper plane of the frame body, and a second fixing frame which is close to the front end of the frame body, is arranged at the right end of the upper plane of the frame body and corresponds to the position of the first fixing frame;
the first workbench is used for arranging an electric control box for controlling the operation of the conveying line, the propelling device, the first sterilizing area, the second sterilizing area and the third sterilizing area;
the gantry frame and the second workbench are used for installing a first killing area;
the first fixing frame and the second fixing frame 23 are used for installing a propelling device;
compared with the prior art, the utility model has the beneficial effects that: has the function of killing the coronavirus on the surface of the article, and enlarges the application range of the electric field coronavirus killing technology.
The technology for killing coronavirus through denaturation of coronavirus spike protein S by electric field induction provided by the utility model is suitable for killing coronavirus on the surface of an article, has the characteristics of simple structure, simplicity and convenience in operation, high killing speed, low killing cost, obvious killing effect and no environmental pollution, can be widely used for killing coronavirus on the surface of the article in air, railway, highway and marine and water transportation logistics, and plays a positive role in preventing the coronavirus from being transmitted on the surface of the article.
Drawings
The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.
Figure 1 is an isometric view of the present invention.
Fig. 2 is a partially enlarged view of the region B shown in fig. 1.
Figure 3 is an isometric view of a frame body of the present invention.
Figure 4 is an isometric view of the present invention.
Fig. 5 is a partially enlarged view of the area a shown in fig. 4.
Fig. 6 is an enlarged partial view of the region C shown in fig. 1.
Fig. 7 is a partially enlarged view of the region D shown in fig. 1.
Fig. 8 is a partially enlarged view of the region E shown in fig. 4.
Fig. 9 is a front view of the present invention.
Fig. 10 is a partial enlarged view of the region F shown in fig. 9.
Fig. 11 is a schematic diagram of the connection of the programmable controller.
Detailed Description
As shown in FIGS. 1-11, a device for disinfecting coronavirus on the surface of an article for inducing the denaturation of spike protein S, which is to pass the article at a constant speed and a constant distance through a distance electrode with the surface of the article formed by a negative electrode and a positive electrode; polarizing and peeling off S1 with positive electrostatic potential energy surface of coronavirus spike protein S on the surface of the article by using the negative pole of the electric field; and (3) polarizing and folding S2 of the coronavirus spike protein S with the negative electrostatic potential energy surface on the surface of the article by using the positive pole of the electric field, so that irreversible denaturation is carried out on the spike protein S to realize killing.
The method is realized by the following steps: after the articles are conveyed by the conveying line 12 and corrected by the propelling device 3, the front, the upper and the rear of the articles are sterilized by the first sterilizing area 13 arranged at the upper part of the conveying line 12, the articles are conveyed to the second sterilizing area 14 by the conveying line 12 to sterilize the left and the right of the articles, and then conveyed to the third sterilizing area 15 by the conveying line 12 to sterilize the lower parts of the articles;
the conveying line 12 comprises a frame body 1, a third sterilizing area 15 arranged at the rear end connection part of the frame body 1, conveying belt devices 2 respectively arranged in the upper end plane of the frame body 1, a second sterilizing area 14 arranged on the frame body 1 and a propelling device 3 arranged on the frame body 1;
the conveying belt device 2 is driven by a speed regulating motor 2-1 arranged at the front end part of the frame body 1, a small chain wheel is arranged on a shaft extension of the speed regulating motor 2-1, the small chain wheel is connected with a large belt wheel on a belt main shaft of the conveying belt device 2 through a chain, one end of a belt is arranged on the belt main shaft, the other end of the belt is arranged on a driven shaft of the frame body 1, a belt tensioner assembly is further arranged between the belt main shaft and the driven shaft, a belt sliding supporting plate is arranged between the belt main shaft and the belt tensioner assembly, and a belt sliding supporting plate is arranged between the belt tensioner assembly and the driven shaft. The small chain wheel is driven by the speed regulating motor, the small chain wheel drives the large chain wheel through the chain, the large chain wheel drives the belt main shaft to rotate, and the main shaft drives the belt to rotate, so that articles placed on the belt move forwards.
The frame body 1 includes a frame body 16 for installing the conveyor line 12 therein, a small frame body 17 disposed at the rear end of the frame body 16 and having the third killing area 15 disposed therein, legs 18 disposed at the front and rear end surfaces of the frame body 16 and supporting the ground, respectively, and a first table 19 disposed behind the legs 18 at the front end of the frame body 16 and connected to the lower end surface of the frame body 16, a second worktable 20 connected with the lower end surface of the frame 16 and arranged behind the first worktable 19, a gantry frame 21 arranged on the upper end surface of the frame 16 and corresponding to the second worktable 20 in position, a first fixing frame 22 close to the front end of the frame body 1 and arranged at the left end of the upper plane of the frame body 1, and a second fixing frame 23 close to the front end of the frame body 1 and arranged at the right end of the upper plane of the frame body 1 and corresponding to the first fixing frame 22 in position;
the first workbench 19 is used for arranging an electric control box 10 for controlling the operation of the conveying line 12, the propelling device 3, the first sterilizing area 13, the second sterilizing area 14 and the third sterilizing area 15;
the gantry frame 21 and the second workbench 20 are used for installing the first killing area 13;
the first fixing frame 22 and the second fixing frame 23 are used for mounting the propelling device 3;
the propulsion device 3 further comprises an actuating mechanism 24 fixedly connected to the first fixing frame 22, a push plate 25 in threaded connection with the end part of the extending end of the actuating mechanism 24, and two distance measuring sensors 26 arranged on the second fixing frame 23; wherein, two distance measuring sensors 26 are arranged up and down on the first vertical rod 23-1 of the second fixing frame 23.
Preferably, the type of the distance measuring sensor 26 is FLR-10-RS485, the distance measuring range is 15-100mm, and the distance measuring sensor is connected with the programmable controller 10-1 through an RS485 communication protocol to feed back distance parameters between the programmable controller 10-1 and the distance measuring sensor 26.
Preferably, the actuator 24 is a linear motor, which facilitates field power connection. According to the requirements of the customer site, the actuating mechanism 24 can also be selected from one of an oil cylinder or an air cylinder for use, the front end of the cylinder body of the oil cylinder or the air cylinder is connected to the first fixing frame 22, and the end part of the piston rod end of the cylinder body of the oil cylinder or the air cylinder is connected with the push plate 25 through threads.
Preferably, the linear motor type as the actuator 24 is: RKD40-400-11-DX-40-B3, linear motor is secured to the cross bar at the upper end of the first mounting bracket 22 with fasteners. The front end of a push rod of the linear motor is in threaded connection with a square plate, holes which are uniformly distributed and arranged are formed in the square plate, the holes which are distributed and arranged are connected with a fastener, and the square plate and the push plate 25 are connected into a whole through the fastener.
Further, the first killing area 13 comprises a horizontal moving device 4 which is arranged at the top of the gantry frame 21 and is parallel to the conveying direction of the conveying line 12, a vertical moving device 5 which is connected with the horizontal moving device 4 and is vertical to the conveying direction of the conveying line 12, a positive static generator 8 and a negative static generator 9 which are arranged on the second workbench 20, distance measuring sensors 26 which are respectively arranged on a front beam 27 and a second upright post 28 of the gantry frame 21, and a scanner 7 which is connected with the vertical moving device 5;
wires with withstand voltage of 150KV are connected to the terminals of the electrode device 6 from the terminals of the positive electrostatic generator 8 and the negative electrostatic generator 9. The electrode device 6 described in the present application is composed of an insulating plate 6-1, a negative electrode 6-2 and a positive electrode 6-3, wherein the negative electrode 6-2 is arranged in front of the insulating plate 6-1, and the positive electrode 6-2 is arranged behind the insulating plate 6-1, so that the negative electric field and the positive electric field generated by the electrode device 6 simultaneously pass through the conveying line 12, the article passes through the negative electric field firstly, then passes through the positive electric field, and the surface of the article is scanned through electric field alternation. The widths of the negative electrode 6-2 and the positive electrode 6-3 of the electrode device 6 are respectively 3 mm.
The coronavirus spike protein S1 is polarized in an electrostatic field to generate stretching and stretching oscillation, and is denatured at a lower electrostatic field intensity, so that the coronavirus spike protein S1 is structurally changed and is irreversibly denatured, thereby achieving the purpose of killing viruses.
The horizontal moving device 4 comprises a linear module 29 which is arranged at the top of the gantry frame 21 and is parallel to the conveying direction of the conveying line 12, and a first sliding table 30 which is connected with a sliding groove 31 on one side surface of the linear module 29 and is used for connecting the vertical moving device 5;
the vertical moving device 5 comprises a linear module 29 which is connected with the first sliding table 30 and is vertical to the conveying direction of the conveying line 12, a second sliding table 33 which is connected with a sliding groove 31 on one side surface of the linear module 29, and a scanner 7 which is connected on the second sliding table 33;
the scanner 7 comprises a supporting rod 34 with one end connected with the fixing plate of the second sliding table 33, a scanning frame 35 connected with the supporting rod 34, and electrode devices 6 respectively arranged at the front end, the rear end and the lower end of the scanning frame 35;
the electrode device 6 comprises an insulating plate 6-1, a negative electrode 6-2 and a positive electrode 6-3, wherein the insulating plate 6-1 is respectively arranged at the front end, the rear end and the lower end of the scanning frame 35, the negative electrode 6-2 is respectively arranged above the insulating plate 6-1 at the front end and the rear end of the scanning frame 35, and the positive electrode 6-3 is respectively arranged below the insulating plate 6-1 at the front end and the rear end of the scanning frame 35; negative electrodes 6-2 are respectively arranged in front of the insulating plate 6-1 at the lower end of the scanning frame 35, and positive electrodes 6-3 are respectively arranged behind the insulating plate 6-1 at the lower end of the scanning frame 35;
further, the width of the scanning frame 35 is equal to the width of the conveying line 12, so as to ensure that the articles on the conveying line 12 can be scanned by the electrode device 6 arranged on the scanning frame 35.
Further, the third killing area 15 disposed inside the small frame 17 is the electrode assembly 6, wherein the insulating plate 6-1 of the electrode assembly 6 is disposed at the inner middle of the small frame 17, the front end of the insulating plate 6-1 is disposed with the negative electrode 6-2 of the electrode assembly 6, and the rear end of the insulating plate 6-1 is disposed with the positive electrode 6-3 of the electrode assembly 6.
Further, the second killing area 14 includes two electrode housings 37, openings of the electrode housings 37 are both arranged toward the conveying line 12, wherein one electrode housing 37 is connected with a front end upright rod 36 at the rear of the frame body 1, and the second killing area further includes a horizontal moving part 38, and a fixed end of the horizontal moving part 38 is connected with the front end upright rod 36 at the rear of the frame body 1, so that an end part of an extending end of the horizontal moving part 38 is connected with the back surface of the other electrode housing 37; the inside of the electrode shell 37 is respectively provided with an insulating plate 6-1 of the electrode device 6, the front end of the insulating plate 6-1 of the electrode shell 37 is respectively provided with a negative electrode 6-2 of the electrode device 6, and the rear end of the insulating plate 6-1 of the electrode shell 37 is respectively provided with a positive electrode 6-3 of the electrode device 6.
Preferably, the horizontal moving member 38 is a linear motor.
Further, the opening of the one electrode housing 37 is aligned with the opening of the other electrode housing 37.
Further, the electric control box 10 is provided with a programmable controller 10-1 and a control panel 10-2, and the output end of the programmable controller 10-1 is respectively connected with a positive static generator 8, a negative static generator 9, a propelling device 3, a first killing area 13, a second killing area 14, a third killing area 15 and a conveyer belt device 2;
the input end of the programmable controller 10-1 is respectively connected with two distance measuring sensors 26 on the second fixing frame 23, the distance measuring sensor 26 on the front beam 27 and the distance measuring sensor 26 on the second upright post 28,
the output end of the positive static generator 8 is respectively connected with a first killing area, a second killing area 14 and a third killing area 15;
the output end of the negative static generator 9 is respectively connected with a first killing area, a second killing area 14 and a third killing area 15;
the control board 10-2 is provided with a main switch 39, a knob 40 for controlling the speed of the conveyor belt device 2, a first switch 41 for controlling the positive static generator 8, and a second switch 42 for controlling the negative static generator 9. The knob 40 is used for controlling a control speed regulator in the conveyor belt device 2, preferably, the control speed regulator is 120W-1220-2 in model, and the first switch 41, the main switch 39 and the second switch 42 are preferably KCD4 in model;
when the device is used, the main switch 39 on the control panel 10-2 is turned on, the device is started, the programmable controller 10-1 controls the propelling device 3, the first killing area 13 and the second killing area 14 to reset, the conveying line 12, the positive electrostatic generator 8 and the negative electrostatic generator 9 are electrified to work, an article passes through the distance measuring sensor 26 on the distance measuring second fixing frame 23 and transmits distance measuring signals to the programmable controller 10-1, and the programmable controller 10-1 adjusts and controls the propelling device 3, the first killing area 13 and the third killing area 15 according to the distance signals.
Example 1
Referring to fig. 1, when the shape of the article to be sterilized is a cuboid or a cube, the sterilized article first passes through the correction area, the article is conveyed by the conveying line 12 and corrected by the pusher 3, the front, back and upper surfaces of the article are sterilized by the first sterilization area 13 disposed at the upper portion of the conveying line 12, the left and right surfaces of the article are sterilized by the conveying line 12 being conveyed to the second sterilization area 14, and the left and right surfaces of the article are conveyed by the conveying line 12 to the third sterilization area 15 to be sterilized below the article.
After the killing device is started, the conveying speed of the conveying line 12 is set to be 4.2m/min, articles run on the conveying line 12 at the speed of 4.2m/min, the articles firstly pass through two distance measuring sensors 26 arranged on a second fixing frame 23, the stroke of an executing mechanism 24 is controlled by the distance measuring sensors 26 arranged below the bottom of a first vertical rod 23-1 on the second fixing frame 23, the distance value between the articles to be killed and the two distance measuring sensors 26 on the second fixing frame 23 is always kept to be 15mm by a push plate 25, the articles are continuously conveyed forwards through the conveying line 12 while being corrected, the distance measuring sensors 26 arranged above the bottom of the first vertical rod 23-1 are used for detecting the front of the articles, and after the front of the articles are detected, the rear of the articles are detected again in the conveying process of the articles;
when the article is conveyed forwards continuously, the article passes through the distance measuring sensor 26 on the front beam 27 of the gantry frame 21, the distance measuring sensor 26 on the front beam 27 detects the height value of the article on the conveying line 12, the height value is obtained by adding 15mm to the zero position distance of the electrode device 6 which is added to the front end of the scanning frame 35 of the scanner 7 and is measured by the distance measuring sensor 26 on the front beam 27, the height value is fed back to the programmable controller 10-1, the programmable controller 10-1 respectively sends electric signals converted after the height value of the article is calculated to the vertical moving device 5, the positive electrostatic generator 8 and the negative electrostatic generator 9 and enables the vertical moving device 5, the positive electrostatic generator 8 and the negative electrostatic generator 9 work, the front end electrode device 6 in the scanner 7 operates and forms a negative electric field and a positive electric field, and by the movement of the vertical moving device 5, when the scanner 7 moves, the front electrode device 6 in the scanner 7 is 15mm away from the front of the article to complete the scanning and disinfection of the front surface of the article, and further, the negative pole of the electric field formed by the electrode device 6 at the front end of the scanning frame 35 is used for polarizing and enabling the S1 with the surface with positive electrostatic potential energy of the coronavirus spike protein S on the front surface of the article to fall off; the positive pole of the electric field formed by the electrode device 6 at the front end of the scanning frame 35 is used for polarizing and folding the S2 with the surface with the negative electrostatic potential energy of the coronavirus spike protein S on the front surface of the article, so that the spike protein S is irreversibly denatured.
Then, the distance value of the front and the back of the detected article is fed back to the programmable controller 10-1 by the ranging sensor 26 arranged above the bottom of the first upright rod 23-1, and the distance of the front of the article and the electrode device 6 at the zero position, which is added to the lower end of the scanning frame 35 of the scanner 7, is obtained by adding 15mm to the distance measured by the ranging sensor 26 above the bottom of the first upright rod 23-1. The programmable controller 10-1 calculates the distance value between the front and the back of the object and converts the calculated electric signals into electric signals which are respectively sent to the horizontal moving device 4, the positive static generator 8 and the negative static generator 9 to work, after the positive static generator 8 and the negative static generator 9 work, the lower electrode device 6 in the scanner 7 operates and forms a negative electromagnetic field and a positive electromagnetic field, the scanning and the disinfection on the object are completed by moving the horizontal moving device 4 and the distance between the lower electrode device 6 in the scanner 7 and the upper surface of the object is 15mm, and then the S1 with the surface with the positive electrostatic potential energy of the coronavirus spike protein S on the surface of the object is polarized and falls off by using the negative electrode of the electric field formed by the electrode device 6 at the lower end of the scanning frame 35; the positive pole of the electric field formed by the electrode device 6 at the front end of the scanning frame 35 is used for polarizing and folding the S2 with the surface with the negative electrostatic potential energy of the coronavirus spike protein S on the upper surface of the article, so that the spike protein S is irreversibly denatured.
The moving distance value of the horizontal moving device 4 is the distance value of the front and the back of the article detected by the distance measuring sensor 26 above the bottom of the first upright 23-1, and the horizontal moving device 4 is controlled by the programmable controller 10-1.
When the horizontal moving device 4 works, the first sliding table 30 of the horizontal moving device 4 drives the vertical moving device 5 to move horizontally, so that the scanner 7 connected with the vertical moving device 5 arranged on the horizontal moving device 4 is close to a cuboid or cube article, and the front end surface of the article is consistent with the conveying direction of the conveying line 12;
when the back of the article is scanned, the distance value of the front and the back of the article detected by the distance measuring sensor 26 arranged above the bottom of the first upright rod 23-1 is fed back to the programmable controller 10-1, and the distance value of the back of the article detected by the distance measuring sensor 26 above the bottom of the first upright rod 23-1 added to the zero position of the electrode device 6 at the back end of the scanning frame 35 of the scanner 7 is obtained by adding 15 mm. The programmable controller 10-1 calculates the distance value between the front and the back of the object and converts the calculated distance value into electric signals which are respectively sent to the horizontal moving device 4, the positive electrostatic generator 8 and the negative electrostatic generator 9 to work, after the positive electrostatic generator 8 and the negative electrostatic generator 9 work, the rear electrode device 6 in the scanner 7 operates and forms a negative electric field and a positive electric field, the vertical moving device 5 moves up and down, and when the scanning disinfection is carried out on the back of the object by the distance between the rear electrode device 6 in the scanner 7 and the back of the object being 15mm, and then the negative electrode of the electric field formed by the electrode device 6 at the back of the scanning frame 35 is utilized to polarize and drop the S1 with the positive electrostatic potential energy surface of the coronavirus spike protein S on the surface of the object; the positive pole of the electric field formed by the electrode device 6 at the front end of the scanning frame 35 is used for polarizing and folding the S2 with the surface with the negative electrostatic potential energy of the coronavirus spike protein S on the upper surface of the article, so that the spike protein S is irreversibly denatured.
Then, the article is conveyed out of the first sterilizing area 13 by the conveying line, after the article completely passes through the distance measuring sensor 26 on the second upright post 28, the distance measuring sensor 26 on the second upright post 28 feeds back the distance value of the front and the back of the article to the programmable controller 10-1, the programmable controller 10-1 respectively sends the electric signals converted by calculating the distance value of the front and the back of the article to the electrode device 6 in the third sterilizing area 15, the two electrode devices 6 arranged in the second sterilizing area 14, the positive electrostatic generator 8 and the negative electrostatic generator 9 and respectively works, after the positive electrostatic generator 8 and the negative electrostatic generator 9 work, the two electrode devices 6 arranged in the second sterilizing area 14 run and form a negative electric field and a positive electric field, the article is moved by the conveying line 12, and when the front of the article first passes through the negative electric field formed by the two electrode devices 6 arranged in the second sterilizing area 14, then passes through a positive electric field formed by two electrode devices 6 arranged in the second killing area 14, then the left and right sides of the article respectively pass through a negative electric field and a positive electric field formed by two electrode devices 6 arranged in the second killing area 14, finally, the back of the article passes through the negative electric field and the positive electric field formed by two electrode devices 6 arranged in the second killing area 14, that is, the left and right sides of the article are scanned and disinfected by the negative electric field and the positive electric field formed by two electrode devices 6 arranged in the second killing area 14, and then the front and the back of the article are scanned again, so that the front and the back are disinfected more thoroughly, and a double-insurance effect is achieved Potential coronavirus infection of the posterior surface.
When the article is transported, the distance value between the article to be killed and the two distance measuring sensors 26 on the second fixing frame 23 is kept at 15mm by controlling the stroke of the actuating mechanism 24 through the distance measuring sensors 26 arranged below the bottom of the first upright rod 23-1, and when the first killing area scans the front, the upper and the rear of the article respectively, the article is scanned at a constant distance of 15mm, so that the article is not touched by any part, and when the left and right surfaces of the article pass through the two electrode devices 6 of the second killing area, the front and rear end surfaces of the article are respectively kept at 15mm with the corresponding electrode devices 6 of the second killing area 14 to complete scanning and disinfection. Further, the negative pole of the electric field formed by the two electrode devices 6 of the second killing area is utilized to polarize and strip the S1 with the positive electrostatic potential energy surface of the coronavirus spike protein S on the left and right surfaces of the article;
the positive pole of the electric field formed by the two electrode devices 6 of the second killing area is used for polarizing and folding the S2 with the surface with the negative electrostatic potential energy of the coronavirus spike protein S on the left and right surfaces of the article, so that the spike protein S is subjected to irreversible denaturation.
The bottom surface of the article is scanned and disinfected through the third disinfection area 15, the upper surface of the electrode device 6 in the small frame 17 is 15mm lower than the upper surface of the conveying line 12, therefore, after the left and right surfaces of the article are disinfected, the bottom surface of the article is scanned and disinfected through the negative electric field and the positive electric field formed by the electrode device 6 in the small frame 17 through the conveying line 12, and further, the negative electrode of the electric field formed by the electrode device 6 in the third disinfection area is used for polarizing and falling off the S1 with the positive electrostatic potential energy surface of the coronavirus spike protein S on the bottom surface of the article; the positive pole of the electric field formed by the electrode device 6 of the third killing area is used for polarizing and folding the S2 with the surface with the negative electrostatic potential energy of the coronavirus spike protein S on the bottom surface of the article, so that the spike protein S is irreversibly denatured. In conclusion, six surfaces of the article are completely sterilized.
The electrode means 6 respectively fulfill the disinfection principle in such a way that: the electrode potential of the electrode devices 6 in the first killing area 13, the second killing area 14 and the third killing area 15 is 5KV-60KV, the distance between the electrode devices 6 and the surface of an object can be adjusted within the range of 1.25 mm-250 mm, and the distance is adjusted by setting the programmable controller 10-1 according to the voltage. This distance range is a range parameter for killing. Not randomly varied during the killing process.
Effective range of electric field intensity is 3 multiplied by 105-4×106V/m, the minimum retention time of the article in the electrode device 6 is 0.04 second, the widths of the negative electrode 6-2 and the positive electrode 6-3 are respectively 3mm, and the conveying linear speed is 4.2 m/min.
The electrode device 6 adopts an electrostatic potential double electrode with a negative electrode 6-3 and a positive electrode 6-3, and the articles sequentially enter a negative electric field area generated by the negative electrode 6-3 in the electrode device 6 and a positive electric field area of the positive electrode 6-2 in the electrode device 6 when passing through the electrode device 6;
the surface with positive electrostatic potential energy of the coronavirus spike protein S1 is polarized and peeled off by a negative electrode in a negative electric field area, and the surface with negative electrostatic potential energy of S2 of the virus after the peeling of S1 is polarized by a subsequent positive electrode to be folded and denatured, so that the purpose of killing the coronavirus is achieved; the electrodes of the device adopt a positive electrostatic potential and a negative electrostatic potential, namely, the positive electrode 6-3 is arranged in front of the negative electrode 6-3, and the negative electrode 6-3 is arranged behind the positive electrode, so that the coronavirus can be killed, but the effect is not as good as that of the negative electrostatic potential and the positive electrostatic potential.
Each electrode device 6 is matched with a negative electrode 6-2 and a positive electrode 6-3, and an insulating plate 6-1 is needed between the negative electrode 6-2 and the positive electrode 6-3 because of high voltage. When the article is killed, each surface of the article firstly passes through the negative electrode and then passes through the positive electrode to increase the killing effect.
Example 2
The electrode device 6 adopts an alternating electric field mode, and when the electrode device works, the alternating electric field mode can form an alternating electric field along with the addition of the electrode device 6; for example, more than two electrode devices 6 are arranged in the small frame 17 in the third killing area 15, so as to form a positive and negative electric field alternating mode, and for example, the second killing area 14 is provided with more than two groups of upright posts 36 on the frame body 1, each upright post 36 is provided with an electrode shell 37, an opening between each electrode shell 37 is arranged towards the conveying line 12, the electrode devices 6 are respectively arranged in the electrode shells 37, the insulating plates 6-1 of the electrode devices 6 are respectively arranged in the electrode shells 37, the front ends of the insulating plates 6-1 of the electrode shells 37 are respectively provided with a negative electrode 6-2 of the electrode devices 6, the rear ends of the insulating plates 6-1 of the electrode shells 37 are respectively provided with a positive electrode 6-3 of the electrode devices 6, so that a negative and positive electric field alternating mode is formed during operation, the positive and negative electric field waveform formed by the electrode devices 6 is a square wave, triangular wave and sine wave, the frequency range is 1K-3KHz, the electrode potential is 2KV-100KV, and the coronavirus spike protein S1 generates stretching oscillation in the alternating electric field, so that the coronavirus spike protein is denatured at a lower electric field intensity, and the purpose of killing viruses is achieved. The number of electrodes in each group is increased, so that the moving speed of the article can be increased on the premise that the coronavirus conforms to the minimum retention time in the electrode area, and the purpose of improving the killing efficiency is achieved.
Example 3
Experimental part
1. Viral virulence (TCID50) assay:
a common method for determining viral toxicity is TCID50, where 50% tissue cell infection (50% Ti tissue infection dose, TCID50) represents the amount of virus that will cause cytopathic effects in 50% of the inoculated cells. Is the dilution of virus that will cause cytopathic effects in half of a monolayer of cells (wells). The method only estimates the intensity and content of virus infectivity, and cannot accurately determine the quantity of infectious virus particles.
Formula of Karber method: lgTCID50 ═ L + d (S-0.5)
In the formula: minimal dilution factor of L-virus
d-dilution factor, i.e. set spacing
S-sum of ratios of cytopathic lesions (ratio of lesions excluding lowest dilution)
For example: TABLE 1
Table 1 shows the measurement table of virus TCID50
L＝-2
D＝-1
S＝4/4+4/4+3/4+2/4+0/4＝4.25
lgTCID50＝L+d(S-0.5)＝-2+(-1)(4.25-0.5)＝-5.75
TCID50＝10-5.75＝1/560000
If the dilutions were all 0.1ml, then 5600000 TCID50 virus titer in 1ml was typically expressed in terms of how many TCID50 were contained per ml.
The experimental results are as follows:
the articles move through the second killing area at a speed of 4.2m/min, and the electrode voltage is 4 × 103V, virus titer (lgTCID50) for changing the distance (r, mm) of the electrode device from the surface of the article;
and (3) measuring results: at a fixed electrode potential, r is inversely proportional to the electric field strength. The virulence of the virus (lgTCID50) was found to be non-linear in response to the electric field at the time of killing, with a window at which killing is best. The experimental data are shown in table 2.
TABLE 2 relationship between electrode assembly and surface distance R of article and virus titer (lgTCID50)
The virulence of the virus (lgTCID50) was found to be non-linear in response to electric field during killing, with a window (field strength 2.7X 10)4V/m, the distance of the electrode from the surface of the article under the experimental conditions is 15mm), the killing effect is best at this window.
The article moves through the second killing area at a speed of V (m/min), and the voltage intensity of the electrode is 4 x 103V, virus titer (lgTCID50) with the distance (15mm) of the electrode device from the surface of the article;
and (3) measuring results: under the condition of fixed electric field intensity, the article running speed is inversely proportional to the killing time. The experimental value reflects that the slow running speed has long killing time and good killing effect, but the actual killing time is short, so that the killing effect of the articles is obviously reduced after the running speed of the articles is 4.5m/min, and 4.2m/min is a feasible condition for considering the killing effect and the efficiency. The experimental data are shown in table 3.
TABLE 3 relationship between article running speed and Virus toxin price (lgTCID50)
The utility model is not limited to the precise arrangements described above and shown in the drawings, and various modifications and changes may be made without departing from the scope thereof. The scope of the utility model is limited only by the appended claims.
Claims (10)
1. An apparatus for sterilizing coronavirus on the surface of an article to induce the denaturation of spike protein S, wherein the article is conveyed by a conveying line (12) and corrected by a propelling device (3), then the front, upper and rear surfaces of the article are sterilized by a first sterilizing area (13) arranged at the upper part of the conveying line (12), then the article is conveyed to a second sterilizing area (14) by the conveying line (12) to sterilize the left and right surfaces of the article, and then conveyed to a third sterilizing area (15) by the conveying line (12) to sterilize the lower surface of the article;
the conveying line (12) comprises a frame body (1), a third killing area (15) arranged at the connection part of the rear end of the frame body (1), conveying belt devices (2) respectively arranged in the upper end plane of the frame body (1), a second killing area (14) arranged on the frame body (1), and a propelling device (3) arranged on the frame body (1);
the frame body (1) comprises a frame body (16) used for arranging the conveying line (12) in the frame body, a small frame body (17) arranged at the rear end of the frame body (16) and arranging the third killing area (15) in the frame body, supporting legs (18) which are respectively arranged on the lower end faces of the front end and the rear end of the frame body (16) and used for supporting the ground, a first workbench (19) arranged behind the supporting legs (18) at the front end of the frame body (16) and connected with the lower end face of the frame body (16), a second workbench (20) connected with the lower end face of the frame body (16) and arranged behind the first workbench (19), a gantry frame (21) arranged on the upper end face of the frame body (16) and corresponding to the position of the second workbench (20), a first fixing frame (22) close to the front end of the frame body (1) and arranged on the right end of the upper plane of the frame body (1) and connected with the first fixing frame (1) (22) A second fixing frame (23) with a corresponding position;
the first workbench (19) is used for arranging an electric control box (10) for controlling the operation of the conveying line (12), the propelling device (3), the first sterilizing area (13), the second sterilizing area (14) and the third sterilizing area (15);
the gantry frame (21) and the second workbench (20) are used for installing the first killing area (13);
the first fixing frame (22) and the second fixing frame (23) are used for mounting the propelling device (3).
2. The apparatus for disinfecting coronavirus on the surface of an article to induce the denaturation of spike protein S as claimed in claim 1, wherein: the propelling device (3) comprises an actuating mechanism (24) fixedly connected to the first fixing frame (22), a push plate (25) in threaded connection with the end part of the extending end of the actuating mechanism (24), and two distance measuring sensors (26) arranged on the second fixing frame (23).
3. The apparatus for disinfecting coronavirus on the surface of an article to induce the denaturation of spike protein S as claimed in claim 1, wherein: the first killing area (13) comprises a horizontal moving device (4) which is arranged at the top of the gantry frame (21) and is parallel to the conveying direction of the conveying line (12), a vertical moving device (5) which is connected with the horizontal moving device (4) and is vertical to the conveying direction of the conveying line (12), a positive static generator (8) and a negative static generator (9) which are arranged on the second workbench (20), distance measuring sensors (26) which are respectively arranged on a front beam (27) and a second upright post (28) of the gantry frame (21), and a scanner (7) which is connected with the vertical moving device (5);
the horizontal moving device (4) comprises a linear module (29) which is arranged at the top of the gantry frame (21) and is parallel to the conveying direction of the conveying line (12), and a first sliding table (30) which is connected with a sliding groove (31) on one side surface of the linear module (29) and is used for connecting the vertical moving device (5);
the vertical moving device (5) comprises a linear module (29) which is connected with the first sliding table (30) and is vertical to the conveying direction of the conveying line (12), a second sliding table (33) which is connected with a sliding groove (31) on one side surface of the linear module (29), and a scanner (7) which is connected with the second sliding table (33);
the scanner (7) comprises a supporting rod (34) with one end connected with the second sliding table (33) fixing plate, a scanning frame (35) connected with the supporting rod (34), and electrode devices (6) respectively arranged at the front end, the rear end and the lower end of the scanning frame (35);
the electrode device (6) comprises an insulating plate (6-1), a negative electrode (6-2) and a positive electrode (6-3), wherein the insulating plate (6-1) is respectively arranged at the front end, the rear end and the lower end of the scanning frame (35), the negative electrode (6-2) is respectively arranged above the insulating plate (6-1) at the front end and the rear end of the scanning frame (35), and the positive electrode (6-3) is respectively arranged below the insulating plate (6-1) at the front end and the rear end of the scanning frame (35); and negative electrodes (6-2) are respectively arranged in front of the insulating plate (6-1) at the lower end of the scanning frame (35), and positive electrodes (6-3) are respectively arranged behind the insulating plate (6-1) at the lower end of the scanning frame (35).
4. The apparatus for disinfecting coronavirus on the surface of an article to induce the denaturation of spike protein S as claimed in claim 3, wherein: the width of the scanning frame (35) is equal to that of the conveying line (12).
5. The apparatus for disinfecting coronavirus on the surface of an article to induce the denaturation of spike protein S as claimed in claim 3, wherein: the third killing area (15) arranged inside the small frame body (17) is an electrode device (6), wherein an insulating plate (6-1) of the electrode device (6) is arranged in the middle of the inside of the small frame body (17), a negative electrode (6-2) of the electrode device (6) is arranged at the front end of the insulating plate (6-1), and a positive electrode (6-3) of the electrode device (6) is arranged at the rear end of the insulating plate (6-1).
6. The apparatus for disinfecting coronavirus on the surface of an article to induce the denaturation of spike protein S as claimed in claim 1, wherein: the second killing area (14) comprises two electrode shells (37), the openings of the electrode shells (37) are arranged towards the conveying line (12), one electrode shell (37) is connected with a front end upright rod (36) at the rear part of the frame body (1), the second killing area also comprises a horizontal moving component (38), and the fixed end of the horizontal moving component (38) is connected with the front end upright rod (36) at the rear part of the frame body (1), so that the end part of the extending end of the horizontal moving component (38) is connected with the back surface of the other electrode shell (37); the electrode shell (37) is internally provided with an insulating plate (6-1) of the electrode device (6), the front end of the insulating plate (6-1) of the electrode shell (37) is provided with a negative electrode (6-2) of the electrode device (6), and the rear end of the insulating plate (6-1) of the electrode shell (37) is provided with a positive electrode (6-3) of the electrode device (6).
7. The apparatus for disinfecting coronavirus on the surface of an article to induce the denaturation of spike protein S as claimed in claim 6, wherein: the opening of the one electrode housing (37) is aligned with the opening of the other electrode housing (37).
8. The apparatus for disinfecting coronavirus on the surface of an article to induce the denaturation of spike protein S as claimed in claim 1, wherein: the electric control box (10) is provided with a programmable controller (10-1) and a control board (10-2), and the output end of the programmable controller (10-1) is respectively connected with a positive static generator (8), a negative static generator (9), a propelling device (3), a first killing area (13), a second killing area (14), a third killing area (15) and a conveyer belt device (2);
the input end of the programmable controller (10-1) is respectively connected with two distance measuring sensors (26) on the second fixing frame (23), the distance measuring sensor (26) on the front beam (27) and the distance measuring sensor (26) on the second upright post (28),
the output end of the positive static generator (8) is respectively connected with the first killing area, (13), the second killing area (14) and the third killing area (15);
the output end of the negative static generator (9) is respectively connected with the first killing area, (13), the second killing area (14) and the third killing area (15);
the control panel (10-2) is provided with a main switch (39), a knob (40) for controlling the speed of the conveyor belt device (2), a first switch (41) for controlling the positive static generator (8) and a second switch (42) for controlling the negative static generator (9).
9. The apparatus for disinfecting coronavirus on the surface of an article to induce the denaturation of spike protein S as claimed in claim 5, wherein: the upper surface of the electrode device (6) in the small frame body (17) is 15mm lower than the upper surface of the conveying line (12).
10. The apparatus for disinfecting coronavirus on the surface of an article to induce the denaturation of spike protein S as claimed in claim 3, wherein: the widths of the negative electrode (6-2) and the positive electrode (6-3) are respectively 3 mm.
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