CN215917699U - Ultrasonic cell crusher convenient to height-adjusting - Google Patents
Ultrasonic cell crusher convenient to height-adjusting Download PDFInfo
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- CN215917699U CN215917699U CN202121601681.9U CN202121601681U CN215917699U CN 215917699 U CN215917699 U CN 215917699U CN 202121601681 U CN202121601681 U CN 202121601681U CN 215917699 U CN215917699 U CN 215917699U
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- cell
- ultrasonic
- cup
- lifting
- height
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- 239000000523 sample Substances 0.000 claims abstract description 26
- 230000001954 sterilising effect Effects 0.000 claims description 5
- 238000004659 sterilization and disinfection Methods 0.000 claims description 2
- 230000000844 anti-bacterial effect Effects 0.000 claims 1
- 210000004027 cell Anatomy 0.000 description 93
- 230000000694 effects Effects 0.000 description 7
- 239000007788 liquid Substances 0.000 description 3
- 230000002070 germicidal effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000005422 blasting Methods 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000003028 elevating effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000001254 nonsecretory effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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Abstract
The utility model discloses an ultrasonic cell crusher convenient for height adjustment, which comprises a cell crusher body, wherein the cell crusher body is fixedly arranged above a lifting bottom plate; a crushing rod installed at an intermediate position inside the cell crusher body; an ultrasonic probe connected below the crushing rod; a cell accommodating cup installed below the ultrasonic probe; a placement groove provided below the cell holding cup; the lifting platform is connected below the placing groove; the telescopic rods are connected to two sides below the lifting platform; and the driving cylinder is connected below the telescopic rod. This ultrasonic wave cell rubbing crusher convenient to height-adjusting compares with current device, can drive lift platform through the telescopic link and carry out the removal from top to bottom to can drive cell and hold the cup and reciprocate in step, and then can hold the cup to the cell as required and carry out the regulation of height, make ultrasonic transducer can fully contact the cell.
Description
Technical Field
The utility model relates to the technical field of B02C19/00 ultrasonic crushing devices, in particular to an ultrasonic cell crusher convenient for height adjustment.
Background
The cell crushing technology is a technology for destroying cell membranes and cell walls by using external force to release target product components, is the basis for separating and purifying non-secretory biochemical substances (products) synthesized in cells, and an ultrasonic cell crusher is used for crushing solid particles or cell tissues in liquid by using the cavitation effect of ultrasonic waves in the liquid to enable the liquid to generate countless small bubbles for blasting;
the existing ultrasonic cell crusher mostly uses a fixed ultrasonic probe, and the probe is difficult to contact cells at the bottom of a container, so that sufficient crushing is difficult to realize, the experiment personnel need to continuously close the machine and manually adjust the height of the container to achieve the purpose of uniform and sufficient crushing, and the working efficiency is greatly reduced.
Chinese patent publication No. CN213315473U discloses an adjustable ultrasonic cell crusher, and the scheme in the patent publication makes the ultrasonic probe on the cell crusher and the central position of the beaker placed on a straight line by adjusting the placement position of the beaker, so as to achieve the capability of improving the crushing effect, but it does not solve the problem that the ultrasonic probe cannot fully contact the cells at the bottom of the beaker during the working process.
The chinese patent publication No. CN109865583A discloses an ultrasonic cell crusher, which is a published patent that prominently solves the problem of low drug quality caused by the continuous rise of temperature during the operation of the device, but the crushing effect of the device during the operation is not reflected.
In view of the above problems, it is of far-reaching importance to develop an ultrasonic cell disruptor that can make an ultrasonic probe sufficiently contact cells by adjusting the height during disruption.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide an ultrasonic cell crusher convenient for height adjustment, and aims to solve the problems that the existing ultrasonic cell crusher mostly uses a fixed ultrasonic probe, the probe is difficult to contact cells at the bottom of a container, so that sufficient crushing is difficult to realize, experimenters are required to continuously close the machine and manually adjust the height of the container to achieve the purpose of uniform and sufficient crushing, and the working efficiency is greatly reduced.
In order to achieve the purpose, the utility model provides the following technical scheme: an ultrasonic cell disruptor facilitating height adjustment comprising:
the lifting device comprises a base, a lifting bottom plate and a lifting handle, wherein the lifting bottom plate is arranged above the base and is parallel to the base;
the cell crusher body is fixedly arranged above the lifting bottom plate;
a crushing rod installed at an intermediate position inside the cell crusher body;
an ultrasonic probe connected below the crushing rod;
a cell accommodating cup installed below the ultrasonic probe;
a placement groove provided below the cell holding cup;
the lifting platform is connected below the placing groove;
the telescopic rods are connected to two sides below the lifting platform;
and the driving cylinder is connected below the telescopic rod.
Preferably, a semi-surrounding structure is formed between the placing groove and the cell containing cup, and the placing groove is overlapped with the vertical central line of the cell containing cup.
Preferably, the placing groove is further provided with:
the elastic rubber ring is connected inside the placing groove, and the cell containing cup forms an elastic structure with the placing groove through the elastic rubber ring.
Preferably, the lifting platform is perpendicular to the placing groove, and the driving cylinder forms a telescopic structure with the lifting platform through a telescopic rod.
Preferably, the lifting bottom plate is further provided with:
and the conveying nut seats are arranged on the left side and the right side of the lifting bottom plate and are symmetrically distributed relative to the vertical center line of the lifting bottom plate.
Preferably, the delivery nut seat is further provided with:
and the conveying screw rod penetrates through the conveying nut seat, a servo motor is connected below the conveying screw rod to realize the adjustment of the vertical position, and a rotating structure is formed between the servo motor and the conveying screw rod.
Preferably, the cell crusher body is further provided with:
a chamber door installed at a front end of the cell crusher body;
and the sterilizing lamps are arranged on the left side and the right side inside the cell crusher body to realize a sterilizing function.
Compared with the prior art, the utility model provides the ultrasonic cell crusher with the height convenient to adjust, which has the following beneficial effects: this ultrasonic wave cell rubbing crusher convenient to height-adjusting can drive lift platform through the telescopic link and carry out the removal from top to bottom to can drive cell and hold the cup and reciprocate in step, and then can hold the cup to the cell as required and carry out the regulation of height, make ultrasonic transducer can fully contact the cell.
1. According to the cell containing cup, the cell containing cup can be placed through the placing groove, meanwhile, the cell containing cup can be limited, and the tightness degree between the placing groove and the cell containing cup can be increased through the elastic rubber ring, so that the placing stability of the cell containing cup can be improved, and the problems that the stability of the high cell containing cup is poor during crushing and the using effect is influenced are solved;
2. the telescopic rod can be stretched by the driving cylinder, so that the lifting platform can be driven to move up and down, the cell containing cup can be driven to synchronously move up and down, the height of the cell containing cup can be adjusted as required, the ultrasonic probe can be in full contact with cells, and the problems that the existing ultrasonic cell crusher mostly uses a fixed ultrasonic probe, the probe is difficult to contact the cells at the bottom of a container, full crushing is difficult to realize, an experimenter needs to continuously close a machine and manually adjust the height of the container to achieve the purpose of uniform and full crushing, and the working efficiency is greatly reduced are solved;
3. according to the utility model, the servo motor can drive the conveying screw rod to rotate, and the rotating conveying screw rod can drive the conveying nut seat to move up and down, so that the lifting bottom plate can be driven to synchronously move, and further, when the lifting device is used, the height of the device can be adjusted according to the requirements of terrain or the personal height, and the like, and the lifting device is convenient to use.
Drawings
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a schematic view of the internal structure of the present invention;
FIG. 3 is a schematic view showing the internal structure of the cell disruptor body according to the present invention;
FIG. 4 is a schematic top view of the standing groove of the present invention;
FIG. 5 is an enlarged view of the structure at A in FIG. 3 according to the present invention.
In the figure: 1. a base; 2. a lifting bottom plate; 3. a cell crusher body; 4. a box door; 5. a conveying screw rod; 6. a delivery nut seat; 7. a servo motor; 8. crushing the stems; 9. an ultrasonic probe; 10. a cell holding cup; 11. a placement groove; 12. an elastic rubber ring; 13. a lifting platform; 14. a telescopic rod; 15. a driving cylinder; 16. a germicidal lamp.
Detailed Description
Example 1 referring to fig. 1 to 2, an ultrasonic cell crusher with a height easily adjusted includes: the lifting device comprises a base 1, wherein a lifting bottom plate 2 is arranged above the base 1, and the lifting bottom plate 2 is parallel to the base 1; a cell crusher body 3 fixedly installed above the elevating base plate 2; a door 4 mounted on the front end of the cell crusher body 3; conveying nut seats 6 which are arranged on the left side and the right side of the lifting bottom plate 2, wherein the conveying nut seats 6 are symmetrically distributed around the vertical central line of the lifting bottom plate 2; the conveying screw rod 5 penetrates through the conveying nut seat 6, the rotary conveying screw rod 5 can drive the conveying nut seat 6 to move up and down, the lifting bottom plate 2 can be driven to move synchronously, and therefore when the lifting nut seat is used, the height of the device can be adjusted according to the requirements of terrain or the height of a user and the like, and the lifting nut seat is convenient to use.
Referring to fig. 2 to 3, an ultrasonic cell crusher with a height easily adjusted includes: a servo motor 7 is connected below the conveying screw rod 5 to realize the adjustment of the upper and lower positions, and a rotating structure is formed between the servo motor 7 and the conveying screw rod 5; the servo motor 7 can drive the conveying screw rod 5 to rotate; a crushing rod 8 installed at an intermediate position inside the cell crusher body 3; an ultrasonic probe 9 connected below the crushing rod 8; and a cell accommodating cup 10 installed below the ultrasonic probe 9.
Referring to fig. 3 to 5, an ultrasonic cell crusher with a height adjustable conveniently comprises: a placement groove 11 provided below the cell holding cup 10; the placing groove 11 can place the cell containing cup 10 and limit the cell containing cup; a semi-surrounding structure is formed between the placing groove 11 and the cell containing cup 10, and the placing groove 11 is superposed with the vertical central line of the cell containing cup 10; an elastic rubber ring 12 connected to the inside of the placement groove 11, wherein the cell holding cup 10 forms an elastic structure with the placement groove 11 through the elastic rubber ring 12; the tightness degree between the placing groove 11 and the cell containing cup 10 can be increased through the elastic rubber ring 12, so that the stability of placing the cell containing cup 10 can be improved, and the problem that the stability of the high cell containing cup 10 is poor and the using effect is influenced when the high cell containing cup 10 is broken is solved; a lifting platform 13 connected below the cell holding cup 10; the telescopic rods 14 are connected to two sides below the lifting platform 13; a driving cylinder 15 connected below the telescopic rod 14; the lifting platform 13 is vertical to the placing groove 11, and the driving cylinder 15 forms a telescopic structure with the lifting platform 13 through a telescopic rod 14; the driving cylinder 15 can enable the telescopic rod 14 to stretch, so that the lifting platform 13 can be driven to move up and down, the cell containing cup 10 can be driven to synchronously move up and down, the height of the cell containing cup 10 can be adjusted as required, the ultrasonic probe 9 can be fully contacted with cells, and the problems that the conventional ultrasonic cell crusher mostly uses a fixed ultrasonic probe, the probe is difficult to contact the cells at the bottom of a container, full crushing is difficult to realize, experimenters need to continuously close the machine and manually adjust the height of the container to achieve the purposes of uniform and full crushing, and the working efficiency is greatly reduced are solved; and germicidal lamps 16 installed at the left and right sides of the inside of the cell crusher body 3 to realize a sterilization function.
The working principle is as follows: when the ultrasonic cell crusher convenient for height adjustment is used, firstly, the base 1 has a bearing effect on the device, when the ultrasonic cell crusher is used, the height of the device is adjusted according to needs, the servo motor 7 is started, the servo motor 7 drives the conveying screw rod 5 to rotate, the rotating conveying screw rod 5 can drive the conveying nut seat 6 to move up and down, and therefore the lifting bottom plate 2 can be driven to synchronously move until the device is adjusted to a proper height; secondly, the sterilizing lamp 16 sterilizes the interior of the cell crusher body 3 in real time to keep the interior of the cell crusher body sanitary, cells are placed in the cell containing cup 10, the box door 4 is opened, the cell containing cup 10 is placed in the placing groove 11, the placing groove 11 can limit the cell containing cup 10, and the tightness between the placing groove 11 and the cell containing cup 10 is increased through the elastic rubber ring 12, so that the placing stability of the cell containing cup 10 is improved, and the problem that the stability of the cell containing cup 10 is poor when the cell containing cup 10 is broken and the using effect is influenced is solved; then the box door 4 is closed, the cell crusher body 3 is started, and the crushing rod 8 drives the ultrasonic probe 9 to crush the cells in the cell holding cup 10; at last, start driving actuating cylinder 15, driving actuating cylinder 15 and driving lift platform 13 through telescopic link 14 and carry out reciprocating's removal from top to bottom, thereby can drive cell and hold cup 10 and reciprocate in step, and then can be when the breakage, make ultrasonic probe 9 fully contact cell hold cup 10 inner cell, realize the abundant crushing of cell, the interval of avoiding between ultrasonic probe and the cell is the fixed value, the probe is difficult to contact the cell of container bottom, thereby be difficult to realize abundant crushing, this is exactly this ultrasonic cell rubbing crusher's the theory of operation of being convenient for height-adjusting.
Claims (10)
1. An ultrasonic cell disruptor convenient to height adjustment, comprising:
the lifting device comprises a base (1), wherein a lifting bottom plate (2) is arranged above the base (1), and the lifting bottom plate (2) is parallel to the base (1);
a cell crusher body (3) fixedly mounted above the lifting bottom plate (2);
a crushing rod (8) installed at an intermediate position inside the cell crusher body (3);
an ultrasonic probe (9) connected below the crushing rod (8);
a cell accommodating cup (10) installed below the ultrasonic probe (9);
a placement tank (11) disposed below the cell holding cup (10);
a lifting platform (13) connected below the placing groove (11);
the telescopic rods (14) are connected to two sides below the lifting platform (13);
and the driving cylinder (15) is connected below the telescopic rod (14).
2. An ultrasonic cell disruptor with height adjustment according to claim 1, characterised in that a semi-enclosed structure is formed between the placement trough (11) and the cell cup (10).
3. An ultrasonic cell disruptor as claimed in claim 1, characterised in that the placement groove (11) coincides with the vertical centre line of the cell receiving cup (10).
4. An ultrasonic cell crusher convenient for height adjustment according to claim 1, characterized in that an elastic rubber ring (12) is connected inside the placing groove (11).
5. An ultrasonic cell crusher convenient for height adjustment according to claim 1, wherein the cell holding cup (10) is formed with an elastic structure by an elastic rubber ring (12) and a placing groove (11).
6. An ultrasonic cell disruptor with height adjustment as convenient as possible according to claim 1 characterised in that the lifting platform (13) and the placement tray (11) are perpendicular to each other.
7. An ultrasonic cell crusher convenient for height adjustment according to claim 1, characterized in that the driving cylinder (15) is connected with the lifting platform (13) through a telescopic rod (14) to form a telescopic structure.
8. An ultrasonic cell disruptor as claimed in claim 1, characterised in that the lifting floor (2) is further provided with:
and the conveying nut seats (6) are arranged on the left side and the right side of the lifting bottom plate (2), and the conveying nut seats (6) are symmetrically distributed relative to the vertical center line of the lifting bottom plate (2).
9. An ultrasonic cell disruptor as claimed in claim 8, characterised in that the conveying nut seat (6) is further provided with:
and the conveying screw rod (5) penetrates through the conveying nut seat (6), a servo motor (7) is connected below the conveying screw rod (5) to realize the adjustment of the vertical position, and a rotating structure is formed between the servo motor (7) and the conveying screw rod (5).
10. An ultrasonic cell crusher convenient to adjust height according to claim 1, characterized in that the cell crusher body (3) is further provided with:
a box door (4) mounted on the front end of the cell crusher body (3);
and bactericidal lamps (16) which are installed on the left and right sides inside the cell crusher body (3) to realize a sterilization function.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121601681.9U CN215917699U (en) | 2021-07-14 | 2021-07-14 | Ultrasonic cell crusher convenient to height-adjusting |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121601681.9U CN215917699U (en) | 2021-07-14 | 2021-07-14 | Ultrasonic cell crusher convenient to height-adjusting |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215917699U true CN215917699U (en) | 2022-03-01 |
Family
ID=80401069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202121601681.9U Expired - Fee Related CN215917699U (en) | 2021-07-14 | 2021-07-14 | Ultrasonic cell crusher convenient to height-adjusting |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN215917699U (en) |
-
2021
- 2021-07-14 CN CN202121601681.9U patent/CN215917699U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20220301 |