CN215916704U - Protease purification device - Google Patents
Protease purification device Download PDFInfo
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- CN215916704U CN215916704U CN202121595926.1U CN202121595926U CN215916704U CN 215916704 U CN215916704 U CN 215916704U CN 202121595926 U CN202121595926 U CN 202121595926U CN 215916704 U CN215916704 U CN 215916704U
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- filter box
- connecting plate
- transmission sleeve
- cylinder
- sedimentation cylinder
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Abstract
The utility model discloses a protease purification device, which comprises a sedimentation cylinder, a filter box and a material guide pipe arranged between the sedimentation cylinder and the filter box; the sedimentation cylinder is conical, the inner peripheral wall of the sedimentation cylinder is provided with a thread line, one side end of the upper part of the sedimentation cylinder is provided with a feeding pipe, the lower part of the sedimentation cylinder is communicated with the impurity settling tank, and one side end of the lower part of the impurity settling tank is provided with a blow-down valve; the middle of the upper part of the filter box is rotatably provided with a transmission sleeve, the upper end of the transmission sleeve is positioned above the filter box and is connected with an upper driving device for driving the transmission sleeve to rotate, the lower end of the transmission sleeve extends into the filter box and is fixedly connected with a first upper connecting plate, and the middle of the first upper connecting plate is provided with a through hole with the same inner diameter as the transmission sleeve; the utility model can automatically realize one-time centrifugal filtration and two-time rotary filter screen filtration of the protease purification solution, effectively improves the filtration efficiency in the protease purification production process and ensures the impurity removal precision.
Description
Technical Field
The utility model relates to the technical field of enzyme treatment devices, in particular to a protease purification device.
Background
The production of the protease needs to be purified and separated, which is briefly to say that the protease firstly breaks biological tissues in the extraction process, then clear liquid is taken and added with a medicament, then the liquid is filled into enzyme extraction equipment, and impurities are filtered out by the equipment to obtain the liquid with high protease content. However, the existing protease purification and extraction equipment has the problems of low solution filtration efficiency and poor impurity removal effect, and needs to be improved.
SUMMERY OF THE UTILITY MODEL
The present invention is directed to a protease purification apparatus, which solves the above-mentioned problems of the prior art.
In order to solve the technical problems, the utility model adopts the following technical scheme:
the utility model relates to a protease purification device which comprises a sedimentation cylinder, a filter box and a material guide pipe arranged between the sedimentation cylinder and the filter box.
The sedimentation cylinder is conical, a thread line is formed in the inner peripheral wall of the sedimentation cylinder, a feeding pipe is arranged at one side end of the upper portion of the sedimentation cylinder, the lower portion of the sedimentation cylinder is communicated with the impurity settling tank, and a blow-down valve is arranged at one side end of the lower portion of the impurity settling tank.
The middle of the upper part of the filter box is rotatably provided with a transmission sleeve, the upper end of the transmission sleeve is positioned above the filter box and is connected with an upper driving device for driving the filter box to rotate, the lower end of the transmission sleeve extends into the filter box and is fixedly connected with a first upper connecting plate, the middle of the first upper connecting plate is provided with a through hole with the same inner diameter as that of the transmission sleeve, the lower part of the first upper connecting plate is fixedly connected with the upper end of a first filter cylinder, and the lower end of the first filter cylinder is fixedly connected with the upper part of a first lower connecting plate; a transmission shaft coaxially arranged with the transmission sleeve is rotatably arranged in the middle of the lower part of the filter box, the lower end of the transmission shaft is positioned below the filter box and is connected with a lower driving device for driving the filter box to rotate, the upper end of the transmission shaft extends into the filter box and is in running fit with the first lower connecting plate, the rear end of the transmission shaft is fixedly connected with a second lower connecting plate, the upper part of the second lower connecting plate is fixedly connected with the lower end of a second filter cylinder, the upper end of the second filter cylinder is fixedly connected with a second upper connecting plate, and a through hole with the same inner diameter as the transmission sleeve is formed in the middle of the second upper connecting plate; and a discharge port is arranged at the lower part of the filter box close to the edge.
One end of the material guide pipe extends to the interior of the sedimentation cylinder from the middle of the upper part of the sedimentation cylinder; the other end of the material guide pipe bends downwards and then sequentially penetrates through the through holes in the transmission sleeve, the first upper connecting plate and the second upper connecting plate and then extends into the second filter cylinder.
Furthermore, a guide pump is arranged in the middle of the guide pipe.
Furthermore, go up drive arrangement including set up in the first motor in rose box upper portion outside, be provided with first action wheel in the drive shaft of first motor, first action wheel is connected through first drive belt and the cover is located the first driven wheel of driving sleeve upper end is connected.
Furthermore, the lower driving device comprises a second motor arranged on the outer side of the lower part of the filter box, a second driving wheel is arranged on a driving shaft of the second motor, and the second driving wheel is connected with a second driven wheel sleeved at the lower end of the transmission shaft through a second transmission belt.
Compared with the prior art, the utility model has the beneficial technical effects that:
the utility model can automatically realize one-time centrifugal filtration and two-time rotary filter screen filtration of the protease purification solution, effectively improves the filtration efficiency in the protease purification production process and ensures the impurity removal precision.
Drawings
The utility model is further illustrated in the following description with reference to the drawings.
FIG. 1 is a schematic structural view of the present invention;
description of reference numerals: 1. a settling cylinder; 2. a filter box; 3. a material guide pipe; 4. a feed pipe; 5. a impurity settling tank; 6. a blowoff valve; 7. a transmission sleeve; 8. a first motor; 9. a first drive wheel; 10. a first drive belt;
11. a first upper connecting plate; 12. a first filter cartridge; 13. a first lower connecting plate; 14. a drive shaft; 15. a second motor; 16. a second drive wheel; 17. a second belt; 18. a second driven wheel; 19. a second lower connecting plate; 20. a second filter cartridge; 21. a second upper connecting plate; 22. a discharge port; 23. a material guide pump; 24. a first driven wheel.
Detailed Description
As shown in fig. 1, a protease purification apparatus includes a settling cylinder 1, a filter tank 2, and a material guide pipe 3 disposed between the settling cylinder 1 and the filter tank 2.
The sedimentation cylinder 1 is conical and is provided with a thread line on the inner peripheral wall, a feeding pipe 4 is installed at one side end of the upper part of the sedimentation cylinder 1, the lower part of the sedimentation cylinder 1 is communicated with a impurity settling tank 5, and a blow-down valve 6 is installed at one side end of the lower part of the impurity settling tank 5.
The middle of the upper part of the filter box 2 is rotatably provided with a transmission sleeve 7, and the upper end of the transmission sleeve 7 is positioned above the filter box 2 and is connected with an upper driving device for driving the filter box to rotate. The upper driving device comprises a first motor 8 arranged on the outer side of the upper part of the filter box 2, a first driving wheel 9 is arranged on a driving shaft of the first motor 8, the first driving wheel 9 is connected with a first driven wheel 24 sleeved at the upper end of the transmission sleeve 7 through a first transmission belt 10, and therefore the transmission sleeve is driven to rotate through the first motor.
The lower end of the transmission sleeve 7 extends to the inside of the filter box 2 and is fixedly connected with a first upper connecting plate 11, and a through hole with the same inner diameter as the transmission sleeve 7 is formed in the middle of the first upper connecting plate 11. The lower part of the first upper connecting plate 11 is fixedly connected with the upper end of the first filter cartridge 12, and the lower end of the first filter cartridge 12 is fixedly connected with the upper part of the first lower connecting plate 13.
The middle of the lower part of the filter box 2 is rotatably provided with a transmission shaft 14 which is coaxially arranged with the transmission sleeve 7, and the lower end of the transmission shaft 14 is positioned below the filter box 2 and is connected with a lower driving device for driving the filter box to rotate. The lower driving device comprises a second motor 15 arranged on the outer side of the lower part of the filter box 2, a second driving wheel 16 is arranged on a driving shaft of the second motor 15, and the second driving wheel 16 is connected with a second driven wheel 18 sleeved at the lower end of the transmission shaft 14 through a second transmission belt 17.
The upper end of the transmission shaft 14 extends into the filter box 2 and is matched with the first lower connecting plate 13 in a rotating manner, the rear end of the transmission shaft is fixedly connected with the second lower connecting plate 19, the upper part of the second lower connecting plate 19 is fixedly connected with the lower end of the second filter cylinder 20, the upper end of the second filter cylinder 20 is fixedly connected with the second upper connecting plate 21, and the middle of the second upper connecting plate 21 is provided with a through hole with the same inner diameter as that of the transmission sleeve 7.
A discharge port 22 is arranged at the lower part of the filter box 2 close to the edge.
One end of the material guiding pipe 3 extends from the middle of the upper part of the sedimentation cylinder 1 to the inside of the sedimentation cylinder 1, and the middle part of the material guiding pipe 3 is provided with a material guiding pump 23. The other end of the material guiding pipe 3 bends downwards and then sequentially passes through the through holes on the transmission sleeve 7, the first upper connecting plate 11 and the second upper connecting plate 21 and then extends into the second filter cartridge 20.
During operation, liquid materials are firstly guided into the settling cylinder through the feeding pipe, under the action of spiral centrifugation inside the settling cylinder, part of heavier impurities can settle into the impurity settling tank at the bottom of the settling cylinder, the liquid materials above the interior of the settling cylinder are guided into the second filter cylinder of the filter box through the material guide pipe, and in the rotation process of the second filter cylinder, the solution is thrown out under the action of the centrifugal force and enters the first filter cylinder.
The above-described embodiments are merely illustrative of the preferred embodiments of the present invention, and do not limit the scope of the present invention, and various modifications and improvements of the technical solutions of the present invention can be made by those skilled in the art without departing from the spirit of the present invention, and the technical solutions of the present invention are within the scope of the present invention defined by the claims.
Claims (4)
1. A protease purification device, its characterized in that: the device comprises a sedimentation cylinder, a filter box and a material guide pipe arranged between the sedimentation cylinder and the filter box;
the sedimentation cylinder is conical, a thread line is arranged on the inner peripheral wall of the sedimentation cylinder, a feeding pipe is arranged at one side end of the upper part of the sedimentation cylinder, the lower part of the sedimentation cylinder is communicated with a impurity settling tank, and a blow-down valve is arranged at one side end of the lower part of the impurity settling tank;
the middle of the upper part of the filter box is rotatably provided with a transmission sleeve, the upper end of the transmission sleeve is positioned above the filter box and is connected with an upper driving device for driving the filter box to rotate, the lower end of the transmission sleeve extends into the filter box and is fixedly connected with a first upper connecting plate, the middle of the first upper connecting plate is provided with a through hole with the same inner diameter as that of the transmission sleeve, the lower part of the first upper connecting plate is fixedly connected with the upper end of a first filter cylinder, and the lower end of the first filter cylinder is fixedly connected with the upper part of a first lower connecting plate; a transmission shaft which is coaxial with the transmission sleeve is rotatably arranged in the middle of the lower portion of the transmission sleeve, the lower end of the filter box is positioned below the filter box and is connected with a lower driving device for driving the filter box to rotate, the upper end of the transmission shaft extends into the filter box and is in running fit with the first lower connecting plate, the end of the transmission shaft is fixedly connected with a second lower connecting plate, the upper portion of the second lower connecting plate is fixedly connected with the lower end of a second filter cylinder, the upper end of the second filter cylinder is fixedly connected with a second upper connecting plate, and a through hole which is the same as the inner diameter of the transmission sleeve is formed in the middle of the second upper connecting plate; a discharge port is formed in the lower part of the filter box close to the edge;
one end of the material guide pipe extends to the interior of the sedimentation cylinder from the middle of the upper part of the sedimentation cylinder; the other end of the material guide pipe bends downwards and then sequentially penetrates through the through holes in the transmission sleeve, the first upper connecting plate and the second upper connecting plate and then extends into the second filter cylinder.
2. The protease purification apparatus according to claim 1, wherein: and a guide pump is arranged in the middle of the guide pipe.
3. The protease purification apparatus according to claim 1, wherein: the upper driving device comprises a first motor arranged on the outer side of the upper part of the filter box, a first driving wheel is arranged on a driving shaft of the first motor, and the first driving wheel is connected with a first driven wheel which is sleeved at the upper end of the transmission sleeve through a first transmission belt.
4. The protease purification apparatus according to claim 1, wherein: the lower driving device comprises a second motor arranged on the outer side of the lower part of the filter box, a second driving wheel is arranged on a driving shaft of the second motor, and the second driving wheel is connected with a second driven wheel sleeved at the lower end of the transmission shaft through a second transmission belt.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121595926.1U CN215916704U (en) | 2021-07-14 | 2021-07-14 | Protease purification device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121595926.1U CN215916704U (en) | 2021-07-14 | 2021-07-14 | Protease purification device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215916704U true CN215916704U (en) | 2022-03-01 |
Family
ID=80400771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202121595926.1U Active CN215916704U (en) | 2021-07-14 | 2021-07-14 | Protease purification device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN215916704U (en) |
-
2021
- 2021-07-14 CN CN202121595926.1U patent/CN215916704U/en active Active
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20220817 Address after: 200120 zone 203, floor 2, building 4, No. 1227 zhangheng road and No. 1118 Harley Road, pilot Free Trade Zone, Pudong New Area, Shanghai Patentee after: Shanghai Yuantian Biotechnology Co.,Ltd. Address before: 102200 1502, west side of the first floor, building 15, area 1, No.8, life Garden Road, Zhongguancun Life Science Park, Huilongguan town, Changping District, Beijing Patentee before: Beijing protocell Biotechnology Co.,Ltd. |