CN215906178U

CN215906178U - Quick virus purification device

Info

Publication number: CN215906178U
Application number: CN202121051165.3U
Authority: CN
Inventors: 潘飞燕; 高源隆
Original assignee: Nanjing Coris Biotechnology Co ltd
Current assignee: Nanjing Coris Biotechnology Co ltd
Priority date: 2021-05-17
Filing date: 2021-05-17
Publication date: 2022-02-25
Anticipated expiration: 2031-05-17

Abstract

The utility model discloses a rapid virus purification device, which comprises a base, wherein the upper surface of the base is fixedly connected with two support plates, the two support plates are positioned at two sides of the upper surface of the base, the upper surfaces of the support plates are fixedly connected with a flat plate, the upper surface of the flat plate is fixedly connected with a solution tank, the upper surface of the flat plate is fixedly connected with a peristaltic pump, the peristaltic pump is positioned at the right side of the solution tank, the upper surface of the flat plate is fixedly connected with four support columns, the four support columns are in square distribution, the upper surfaces of the support columns are fixedly connected with a mounting plate, and the upper surface of the base is fixedly connected with a waste bottle I. Brings certain beneficial effect to the practical use.

Description

Quick virus purification device

Technical Field

The utility model relates to the technical field of medical devices, in particular to a rapid virus purification device.

Background

The virus culture solution contains a large amount of impurities, including defective particles, virus shells, cytotoxins, culture media, serum, cell debris and the like, which can cause strong host immune reaction when injected into animal bodies, and purification is beneficial to suspension of viruses in buffer solution for in vivo injection.

SUMMERY OF THE UTILITY MODEL

The utility model aims to provide a rapid virus purification device which has the advantages that impurities which cannot be separated by a centrifuge can be further separated, and small molecular impurities such as water, salt and the like can be filtered out through an ultrafiltration membrane, so that certain beneficial influence is brought to practical use, and the problems in the background art are solved.

In order to achieve the purpose, the utility model provides the following technical scheme: the utility model provides a quick virus purification device, includes the base, two backup pads of last fixed surface of base are connected with, and two backup pads are located the both sides of base upper surface, the last fixed surface of backup pad is connected with dull and stereotypedly, dull and stereotyped last fixed surface is connected with the solution tank, dull and stereotyped last fixed surface is connected with the peristaltic pump, and the peristaltic pump is located the right side of solution tank, four support columns of dull and stereotyped last fixed surface are connected with, and four support columns are the square distribution, the last fixed surface of support column is connected with the mounting panel, the last fixed surface of base is connected with waste bottle one.

Preferably, the water inlet fixedly connected with transfer line of peristaltic pump, and the transfer line keep away from one side of peristaltic pump and the delivery port fixed connection of solution tank, the delivery port fixedly connected with liquid feeding pipe of peristaltic pump, the one end fixedly connected with centrifuge that the peristaltic pump was kept away from to liquid feeding pipe, be provided with first sluice on the liquid feeding pipe.

Preferably, the lower surface of centrifuge is connected with the upper surface fixed connection of mounting panel, the first waste liquid pipe of centrifuge mouth fixedly connected with of centrifuge, and the lower surface of first waste liquid pipe and the entry fixed mounting of waste material bottle one, centrifuge's precipitation mouth fixedly connected with sedimentation tube.

Preferably, the lower fixed surface of sedimentation tube is connected with first filtration jar, the inside of first filtration jar is provided with macromolecule filtration membrane, the delivery port fixedly connected with chimney filter of first filtration jar, be provided with the second sluice on the chimney filter.

Preferably, the lower fixed surface of chimney filter is connected with the second and filters the jar, and the second filters the upper surface of jar and is connected with dull and stereotyped lower fixed surface, be provided with the milipore filter in the second filters the jar, the left fixed surface that the jar was filtered to the second is connected with the connecting pipe, and the connecting pipe is located the top of milipore filter, the lower extreme fixedly connected with purification bottle of connecting pipe.

Preferably, the lower surface of the second filter tank is fixedly connected with a second waste pipe, and the lower end of the second waste pipe is fixedly connected with a second waste bottle.

Compared with the prior art, the utility model has the beneficial effects that: the utility model discloses a virus purification bottle, including centrifuge, the setting up of centrifuge can be with the quick isolate solution of macromolecular impurity, the impurity of isolating gets into waste bottle one through first waste pipe, other solutions pass through the sedimentation tube and get into in the first filtration jar, can further isolate the impurity that centrifuge can not isolate through macromolecular filtration membrane in first filtration jar, and the solution that will filter finishing passes through the chimney filter and sends to the second in filtering jar, can be with moisture through the milipore filter in the second filtration jar, micromolecular impurities such as salinity filter away, micromolecular impurity passes through in second waste pipe gets into waste tank two, wait to filter and open the virus solution after finishing opening the third sluice and transporting to the purification bottle through the connecting pipe and preserve.

Drawings

FIG. 1 is a front sectional view of the present invention;

the figure is a front view of the present invention.

In the figure: 1. a base; 2. a support plate; 3. a flat plate; 4. a solution tank; 5. a peristaltic pump; 6. a support pillar; 7. mounting a plate; 8. a transfusion tube; 9. a liquid delivery pipe; 10. a centrifuge; 11. a first sluice; 12. a first waste liquid pipe; 13. a settling tube; 14. a macromolecular filtering membrane; 15. a filter tube; 16. a second sluice; 17. a second filtration tank; 18. ultrafiltration membranes; 19. a connecting pipe; 20. purifying the bottle; 21. a second waste pipe; 22. a waste bottle II; 23. a waste bottle I; 24. a third sluice; 25. a first filtration tank.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1 to fig. 2, the present invention provides a technical solution: the utility model provides a quick virus purification device, includes base 1, two backup pads 2 of base 1's last fixed surface are connected with, and two backup pads 2 are located the both sides of base 1 upper surface, the last fixed surface of backup pad 2 is connected with dull and stereotyped 3, dull and stereotyped 3 last fixed surface is connected with solution tank 4, dull and stereotyped 3 last fixed surface is connected with peristaltic pump 5, and peristaltic pump 5 is located the right side of solution tank 4, can be with the solution in the solution tank 4 slowly transport in the centrifuge 10 through setting up of peristaltic pump 5.

Furthermore, a liquid conveying pipe 8 is fixedly connected to a water inlet of the peristaltic pump 5, one side, away from the peristaltic pump 5, of the liquid conveying pipe 8 is fixedly connected to a water outlet of the solution tank 4, a liquid conveying pipe 9 is fixedly connected to a water outlet of the peristaltic pump 5, and a centrifuge 10 is fixedly connected to one end, away from the peristaltic pump 5, of the liquid conveying pipe 9.

Further, the lower surface of centrifuge 10 and the upper surface fixed connection of mounting panel 7, the first waste liquid pipe 12 of centrifuge 10's centrifugation mouth fixedly connected with, and the lower surface of first waste liquid pipe 12 and the entry fixed mounting of waste material bottle 8, centrifuge 10's precipitation mouth fixedly connected with sedimentation tube 13.

Further, the first jar 25 that filters of lower surface fixedly connected with of sedimentation pipe 13 can further separate away the impurity that centrifuge 10 can not separate through macromolecular filtration membrane 14 in first jar 25 that filters to in the solution that will filter and finish passes through filtration pipe 15 and sends second filtration jar 17, the inside of first jar 25 that filters is provided with macromolecular filtration membrane 14, the first delivery port fixedly connected with filtration pipe 15 that filters jar 25.

Further, the lower surface fixed connection of chimney filter 15 has the second to filter jar 17, and the upper surface that the second filtered jar 17 and dull and stereotyped 3's lower surface fixed connection, can filter out moisture, micromolecule impurity such as salinity through milipore filter 18 in the second filters jar 17, and micromolecule impurity gets into in the waste tank two 22 through second waste pipe 21.

Further, a second waste liquid pipe 21 is fixedly connected to the lower surface of the second filter tank 17, and a second waste material bottle 22 is fixedly connected to the lower end of the second waste liquid pipe 21.

An ultrafiltration membrane 18 is arranged in the second filtering tank 17, a connecting pipe 19 is fixedly connected to the left surface of the second filtering tank 17, the connecting pipe 19 is located above the ultrafiltration membrane 18, a third water gate 24 is arranged on the connecting pipe, and a purification bottle 20 is fixedly connected to the lower end of the connecting pipe 19.

The filter tube 15 is provided with a second sluice 16.

The liquid sending pipe 9 is provided with a first sluice 11.

Dull and stereotyped 3's upper surface fixed connection has four support columns 6, and four support columns 6 are the square distribution, and the last fixed surface of support column 6 is connected with mounting panel 7, and the last fixed surface of base 1 is connected with waste bottle 23.

The working principle is as follows: this purification device is when using, the staff pours into solution tank 4 with the solution that needs the purification, start peristaltic pump 5, can slowly transport the centrifuge 10 with the solution in solution tank 4 through setting up of peristaltic pump 5 in, start centrifuge 10, can be with the quick solution that separates of macromolecular impurity through setting up of centrifuge 10, the impurity of separating gets into waste bottle 23 through first waste liquid pipe 12 in, other solutions get into first filter tank 25 through sedimentation tube 13 in, can further separate away the impurity that centrifuge 10 can not separate out through macromolecular filtration membrane 14 in first filter tank 25, and send the solution that finishes filtering to second filter tank 17 through chimney filter 15 in, second filter tank 17 closes second sluice 16 when full, can filter away moisture, micromolecular impurities such as salinity through milipore filter 18 in second filter tank 17, the micromolecule impurities enter the second waste material tank 22 through the second waste liquid pipe 21, and after the filtration is finished, the third sluice 24 is opened to convey the purified virus solution to the purification bottle 20 through the connecting pipe 19 for storage.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A rapid virus purification device, comprising a base (1), characterized in that: the utility model discloses a waste material bottle, including base (1), two backup pads (2) of last fixed surface of base (1), and two backup pads (2) are located the both sides of base (1) upper surface, the last fixed surface of backup pad (2) is connected with flat board (3), the last fixed surface of flat board (3) is connected with solution tank (4), the last fixed surface of flat board (3) is connected with peristaltic pump (5), and peristaltic pump (5) are located the right side of solution tank (4), four support columns (6) of the last fixed surface of flat board (3) are connected with, and four support columns (6) are the square and distribute, the last fixed surface of support column (6) is connected with mounting panel (7), the last fixed surface of base (1) is connected with waste material bottle (23).

2. The rapid virus purification device of claim 1, wherein: the water inlet fixedly connected with transfer line (8) of peristaltic pump (5), and transfer line (8) keep away from one side of peristaltic pump (5) and the delivery port fixed connection of solution tank (4), the delivery port fixedly connected with liquid delivery pipe (9) of peristaltic pump (5), the one end fixedly connected with centrifuge (10) of peristaltic pump (5) is kept away from in liquid delivery pipe (9), be provided with first sluice (11) on liquid delivery pipe (9).

3. The rapid virus purification device of claim 2, wherein: the lower surface of centrifuge (10) is connected with the last fixed surface of mounting panel (7), the first waste liquid pipe of centrifugation mouth fixedly connected with (12) of centrifuge (10), and the lower surface of first waste liquid pipe (12) and the entry fixed mounting of waste material bottle (8), the sediment mouth fixedly connected with sedimentation tube (13) of centrifuge (10).

4. The rapid virus purification device of claim 3, wherein: the lower surface fixedly connected with of sedimentation pipe (13) first filters jar (25), the inside of first filtration jar (25) is provided with macromolecule filtration membrane (14), the delivery port fixedly connected with filter tube (15) of first filtration jar (25), be provided with second sluice (16) on filter tube (15).

5. The rapid virus purification device of claim 4, wherein: the lower fixed surface of chimney filter (15) is connected with the second and filters jar (17), and the second filters the upper surface of jar (17) and the lower fixed surface of flat board (3) is connected, the second is provided with milipore filter (18) in filtering jar (17), the left fixed surface of second filter jar (17) is connected with connecting pipe (19), and connecting pipe (19) are located the top of milipore filter (18), be provided with third sluice (24) on connecting pipe (19), the lower extreme fixedly connected with purification bottle (20) of connecting pipe (19).

6. The rapid virus purification device of claim 5, wherein: the lower surface fixedly connected with second waste liquid pipe (21) of second filtration jar (17), the lower extreme fixedly connected with waste bottle two (22) of second waste liquid pipe (21).