CN215894637U - Antigen prosthetic devices - Google Patents

Antigen prosthetic devices Download PDF

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Publication number
CN215894637U
CN215894637U CN202121390598.1U CN202121390598U CN215894637U CN 215894637 U CN215894637 U CN 215894637U CN 202121390598 U CN202121390598 U CN 202121390598U CN 215894637 U CN215894637 U CN 215894637U
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Prior art keywords
inner container
container
heating
antigen
antigen retrieval
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CN202121390598.1U
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Chinese (zh)
Inventor
崔红米
陈鹏
赵琳琳
邢雅南
张林姿
牛银银
李三华
齐华
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Henan Celnovtebio Biotechnology Inc
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Henan Celnovtebio Biotechnology Inc
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Abstract

The utility model relates to an antigen retrieval device, which comprises a heating container and an inner container, wherein the inner container is positioned in the heating container; the inner container support is arranged between the inner container and the heating container and supports the inner container to enable the inner container and the container wall of the heating container to be arranged at intervals, and a heating container repairing cavity for containing antigen repairing liquid is formed between the inner container and the heating container. The heating container repair cavity is formed between the inner container and the heating container of the antigen repair device, the inner container repair cavity is formed in the inner container, and can be used for simultaneously repairing different antigen repair liquids, so that the repair efficiency is improved.

Description

Antigen prosthetic devices
Technical Field
The utility model relates to an antigen retrieval device.
Background
Immunohistochemistry is a technology which utilizes the principle of combining antigen and antibody and makes the marked antibody develop color through chemical reaction so as to perform qualitative, positioning and quantitative determination on corresponding antigen. With the development of pathological techniques, the position of immunohistochemistry in the pathology department is gradually increased. For immunohistochemical manual experiments, the antigens to be detected are diverse, and the repair conditions required to detect different antigens may also vary. The currently commonly used repair solutions comprise citric acid with pH6.0, Tris-EDTA with pH8.0 and Tris-EDTA with pH9.0, except for the differences of the repair solutions, some laboratories can also adopt mild heat insulation repair in order to reduce the flaking rate, namely, an incubation box is put into a pressure cooker for repair; at present, pressure cookers used in laboratories are single pot bodies, different antigen repairing liquids with different heating speeds are needed, repairing needs to be carried out in batches usually, working time and workload are greatly increased, and the technical problem of low repairing efficiency exists.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide an antigen retrieval device, which is used for solving the technical problem of low retrieval efficiency caused by the adoption of batch retrieval antigens at present.
The antigen retrieval device adopts the following technical scheme:
an antigen retrieval device comprising:
the heating container is used for accommodating the antigen repairing liquid to heat the antigen repairing liquid and is provided with an upward heating container opening;
the inner container is positioned in the heating container and is provided with an inner container repairing cavity for containing the antigen repairing liquid and an upward inner container opening;
and the inner container bracket is positioned between the inner container and the heating container and supports the inner container to enable the inner container and the container wall of the heating container to be arranged at intervals, and a heating container repairing cavity for containing the antigen repairing liquid is formed between the inner container and the heating container.
Has the advantages that: the heating container repair cavity is formed between the inner container and the heating container of the antigen repair device, the inner container repair cavity is formed in the inner container, and can be used for simultaneously repairing different antigen repair liquids, so that the repair efficiency is improved.
Furthermore, the number of the heating container repair cavities is at least two, and the inner container support and the outer wall of the inner container hermetically separate the heating container repair cavities. Can be applied to a wider variety of antigen retrieval solutions.
Furthermore, the inner container support comprises at least three L-shaped frames, each L-shaped frame comprises a horizontal part and a vertical part extending upwards from one end of the horizontal part, the horizontal parts of the L-shaped frames are arranged in a radial mode, one ends, far away from the vertical parts, of the horizontal parts are connected together, the inner container support supports the inner container through the horizontal parts of the L-shaped frames, and the outer side wall surface of the inner container is horizontally positioned through the vertical parts. The three L-shaped supports can better position the inner container, thereby being convenient for fixing the inner container.
Further, at least two inner container repair cavities are arranged, and inner container separation frames for sealing and separating adjacent inner container repair cavities are arranged in the inner containers. Further increasing the number of repair cavities and being suitable for more kinds of repair liquid.
Further, the inner vessel spacer is made of a metal material. The heat conduction effect is better, makes the temperature in each interior container restoration chamber unanimous.
Further, the inner vessel holder is made of a metal material. The temperature of each heating container repairing cavity is consistent.
Further, the inner container is made of a heat insulating material. Further reducing the temperature rise speed of the inner container repairing cavity.
Furthermore, a heating container sealing cover for covering the heating container opening is detachably arranged on the heating container, and a pressure limiting valve is arranged on the heating container sealing cover. And the high-pressure repair requirement is met.
Furthermore, an inner container sealing cover for covering the opening of the inner container can be detachably arranged on the inner container, and an air hole for communicating the inner container repairing cavity with the heating container repairing cavity is formed in the inner container sealing cover. And the high-pressure repair requirement is met.
Furthermore, the antigen retrieval device is a pressure cooker, and the heating container forms an outer cooker body of the pressure cooker.
Drawings
FIG. 1 is a cross-sectional view of an antigen retrieval device embodiment 1 of the present invention;
FIG. 2 is a schematic structural view of an antigen retrieval device according to embodiment 1 of the present invention;
FIG. 3 is a top view of an antigen retrieval device embodiment 1 of the present invention;
FIG. 4 is an exploded view of an antigen retrieval device according to embodiment 1 of the present invention;
in the figure: 1. heating the container; 11. heating the container repair cavity; 2. an inner container; 21. an inner container repair cavity; 3. an inner container support; 31. an L-shaped frame; 311. a horizontal portion; 312. a vertical portion; 4. a heating container sealing cover; 41. a safety valve; 42. a pressure limiting valve; 43. an alarm valve; 5. an inner container separation frame; 51. a separator.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the detailed description and specific examples, while indicating the preferred embodiment of the utility model, are intended for purposes of illustration only and are not intended to limit the scope of the utility model. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the utility model, as claimed, but is merely representative of selected embodiments of the utility model. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present invention without making any creative effort, shall fall within the protection scope of the present invention.
It is noted that relational terms such as "first" and "second," and the like, may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
The features and properties of the present invention are described in further detail below with reference to examples.
Specific embodiment 1 of an antigen retrieval device of the present invention:
as shown in fig. 1 to 4, an antigen retrieval device includes a heating container 1, an inner container 2, and an inner container holder 3, the heating container 1 being for containing and heating an antigen retrieval liquid. The inner container 2 is arranged in the heating container 1, an inner container repairing cavity 21 for containing antigen repairing liquid and an upward inner container opening are arranged in the inner container 2, and the antigen repairing liquid and the experimental slide are placed in the inner container opening. The inner container support 3 is arranged between the inner container 2 and the heating container 1 and used for supporting the inner container 2, the inner container 2 and the container wall of the heating container 1 are arranged at intervals, and a heating container repairing cavity 11 used for containing antigen repairing liquid is formed between the inner container 2 and the heating container 1. The heating container is provided with an upward heating container opening, and the heating container opening is used for placing the antigen repairing liquid and the glass slide. In this embodiment, the inner cavity of the inner container 2 is always communicated with the inner cavity of the heating container 1.
The inner container repairing cavity 21 and the heating container repairing cavity 11 can be adapted to simultaneous repairing of different antigen repairing liquids, and in addition, because heat needs to be transferred from the heating container repairing cavity to the inner container repairing cavity, the temperature rising speed of the inner container repairing cavity is low, the requirement of mild repairing conditions can be met, and the antigen repairing efficiency is further improved.
In order to achieve a large temperature difference, in the present embodiment, the inner container 2 is made of a heat insulating material, so that there is a large temperature difference between the temperature inside the inner container 2 and the temperature outside the inner container 2, and it is easier to satisfy the requirement of mild repair conditions. In this embodiment, the inner container is made of a high molecular polymer material.
In this embodiment, the antigen retrieval device is a pressure cooker, wherein the heating container 1 constitutes an outer body of the pressure cooker. The lid of the pressure cooker constitutes a heating container sealing lid 4 on the heating container 1. The heating container sealing cover 4 is provided with a safety valve 41, a pressure limiting valve 42 and an alarm valve 43. Handles are arranged on the outer heating container 1 and the sealing cover 4 of the heating container, so that the operation is convenient.
The inner container support 3 comprises three L-shaped frames 31, each L-shaped frame 31 comprises a horizontal part 311 and a vertical part 312 extending upwards from one end of the horizontal part 311, one end of each horizontal part 311 of each L-shaped frame 31 far away from the vertical part 312 is connected together, and the inner container support 3 supports the inner container 2 through the horizontal part 311 of each L-shaped frame 31 and is horizontally positioned with the outer side wall surface of the inner container 2 through the vertical part 312. The three L-shaped frames 31 hermetically divide the cavity between the inner vessel 2 and the heating vessel 1 into three mutually independent heating vessel repair chambers 11. The inner container support has a simple structure, has a good positioning effect on the inner container, and is convenient to install.
In order to make the temperatures in the three heating container repair chambers 11 consistent, the inner container support 3 is made of a metal material, specifically, a stainless steel material in this embodiment.
In this embodiment, an inner container separation frame 5 for separating the cavity of the inner container 2 is arranged in the inner container 2, and the inner container separation frame 5 hermetically separates the cavity of the inner container 2 into three inner container repair cavities 21. In order to ensure that the temperatures of the three inner container repair chambers 21 are consistent, the inner container separation frame 5 is also made of a metal material, and in the embodiment, a stainless steel material is adopted.
In this embodiment, the inner container separation frame 5 includes three partition plates 51, the three partition plates 51 are vertically arranged, one vertical edge of each of the three partition plates 51 is connected together, and the other vertical edge is in sealing fit with the side wall of the inner container 2, in this embodiment, the three partition plates 51 are in bonding seal with the inner container.
In the embodiment, the inner container support, the inner container and the inner container separation frame are fixedly bonded, the inner container support is fixedly welded in the heating container, all the parts are fixed together and are not easy to lose, and the sealing is convenient. The plectrum frame for placing the plectrum is arranged in the inner container repairing cavity 21 and the heating container repairing cavity 11, so that the repairing efficiency is improved.
When the antigen retrieval device is used, the antigen retrieval liquid is poured into the corresponding retrieval cavity, and the heating container retrieval cavity and the inner container retrieval cavity are independent cavities, so that six kinds of antigen retrieval liquid can be used simultaneously. The inner container is made of heat insulating materials, and the inner container is utilized to repair the cavity, so that the requirement of mild repair can be met. Of course, the same antigen retrieval solution can be poured into the six retrieval cavities according to actual needs.
The specific embodiment 2 of an antigen retrieval device of the present invention: the difference from the above embodiment is that the inner container is detachably provided with an inner container sealing cover for covering the opening of the inner container, the inner container sealing cover is in threaded connection with the inner container, and the inner container sealing cover is provided with an air hole for communicating the inner container repairing cavity with the heating container repairing cavity.
The specific embodiment 3 of an antigen retrieval device of the present invention: the only difference from the above embodiment is that in this embodiment, only one heating container repair chamber is provided, and the inner container support does not divide the cavity between the inner container and the heating container, and the inner container support can be provided at the bottom of the inner container.
Specific embodiment 4 of an antigen retrieval device of the present invention: the only difference from the above described embodiment is that in this embodiment the inner vessel is made of a metallic material.
Specific example 5 of an antigen retrieval device of the present invention: the only difference from the above embodiment is that in this embodiment, the heating container is open for use, a sealing cover for the heating container is not required, and a sealing cover for the inner container is provided on the inner container.
Specific example 6 of an antigen retrieval device of the present invention: the only difference from the above embodiment is that in the present embodiment, two heating container repair chambers are provided. In other embodiments, the number of the repair cavities may be increased or decreased, for example, four or more, as required.
Specific example 7 of an antigen retrieval device of the present invention: the only difference from the above described embodiment is that in this embodiment the inner container spacer is made of a heat insulating material.
The specific embodiment 8 of an antigen retrieval device of the present invention: the only difference from the above described embodiment is that in this embodiment there is one inner container repair chamber, in which case no inner container spacer is required in the inner container. In other embodiments, the number of the repair cavities of the south street container can be two, four, etc. according to the requirement.
The specific embodiment of an antigen retrieval device of the present invention is as follows: the difference from the above embodiments is only that in the present embodiment, the inner container is detachable, and the space between the inner container and the inner container bracket is sealed by a rubber strip. In other embodiments, the inner container separation frame and the inner wall surface of the inner container can be sealed by a rubber strip, and the inner container separation frame and the inner container can also be detached.
The above description is only a preferred embodiment of the present invention, and not intended to limit the present invention, the scope of the present invention is defined by the appended claims, and all structural changes that can be made by using the contents of the description and the drawings of the present invention are intended to be embraced therein.

Claims (10)

1. An antigen retrieval device, comprising:
a heating container (1) for containing the antigen retrieval liquid to heat the antigen retrieval liquid, and having an upward heating container opening;
the inner container (2) is positioned in the heating container (1) and is provided with an inner container repairing cavity (21) for containing antigen repairing liquid and an upward inner container opening;
and the inner container support (3) is positioned between the inner container (2) and the heating container (1) and supports the inner container (2) to enable the inner container (2) and the container wall of the heating container (1) to be arranged at intervals, and a heating container repairing cavity (11) for containing antigen repairing liquid is formed between the inner container (2) and the heating container (1).
2. The antigen retrieval device of claim 1, wherein the heating container repair chambers (11) are at least two, and the inner container holder (3) and the outer wall of the inner container hermetically separate the heating container repair chambers (11).
3. The antigen retrieval device of claim 2 wherein the inner container support (3) comprises at least three L-shaped frames (31), the L-shaped frames (31) comprise horizontal portions (311) and vertical portions (312) extending upward from one end of the horizontal portions (311), the horizontal portions (311) of each L-shaped frame (31) are arranged radially, and ends of the horizontal portions (311) remote from the vertical portions (312) are connected together, the inner container support (3) supports the inner container (2) through the horizontal portions (311) of the L-shaped frames (31), and the outer side wall surface of the inner container (2) is positioned horizontally through the vertical portions (312).
4. Antigen retrieval device according to any of claims 1-3, characterized in that at least two inner container retrieval chambers (21) are provided, and an inner container separator (5) for sealing off adjacent inner container retrieval chambers (21) is provided within the inner container (2).
5. Antigen retrieval device according to claim 4, characterized in that the inner container spacer (5) is made of a metallic material.
6. Antigen retrieval device according to any of claims 1-3, characterized in that the inner container holder (3) is made of a metallic material.
7. Antigen retrieval device according to any of claims 1-3, characterized in that the inner container (2) is made of a heat insulating material.
8. The antigen retrieval device according to any one of claims 1 to 3, wherein the heating container (1) is detachably provided with a heating container sealing cover (4) for covering the opening of the heating container, and the heating container sealing cover (4) is provided with a pressure limiting valve (42).
9. The antigen retrieval device of any one of claims 1-3 wherein the inner container (2) is removably provided with an inner container sealing lid covering the mouth of the inner container, the inner container sealing lid being provided with an air vent communicating the inner container retrieval chamber with the heated container retrieval chamber.
10. The antigen retrieval device according to any one of claims 1 to 3, wherein the antigen retrieval device is a pressure cooker, and the heating container (1) constitutes an outer body of the pressure cooker.
CN202121390598.1U 2021-06-22 2021-06-22 Antigen prosthetic devices Active CN215894637U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202121390598.1U CN215894637U (en) 2021-06-22 2021-06-22 Antigen prosthetic devices

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202121390598.1U CN215894637U (en) 2021-06-22 2021-06-22 Antigen prosthetic devices

Publications (1)

Publication Number Publication Date
CN215894637U true CN215894637U (en) 2022-02-22

Family

ID=80500635

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202121390598.1U Active CN215894637U (en) 2021-06-22 2021-06-22 Antigen prosthetic devices

Country Status (1)

Country Link
CN (1) CN215894637U (en)

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