CN215894150U

CN215894150U - Cell smear device

Info

Publication number: CN215894150U
Application number: CN202121403054.4U
Authority: CN
Inventors: 赵琳琳; 邢雅南; 米贯勋; 张林姿; 牛银银; 李三华; 刘文弟; 齐华
Original assignee: Henan Celnovtebio Biotechnology Inc
Current assignee: Henan Celnovtebio Biotechnology Inc
Priority date: 2021-06-23
Filing date: 2021-06-23
Publication date: 2022-02-22
Anticipated expiration: 2031-06-23

Abstract

The utility model relates to a cell smear device which comprises a film making bin base, a film making bin and a glass slide, wherein the film making bin is detachably fixed on the film making bin base, a filter cup is arranged in the film making bin and used for filtering sample solution with cells, a film making bin opening through which the sample solution with cells passes is formed in the bottom of the film making bin, and the glass slide is arranged on the film making bin base and used for being in sealing fit with the film making bin opening. The film-making storehouse has two at least, is equipped with the isolation tank on the slide glass, and the notch of isolation tank supplies the cell relatively from the film-making storehouse to get into the isolation tank with the film-making storehouse mouth, and a film-making storehouse corresponds at least one isolation tank. The utility model aims to provide a cell smear device, which is used for solving the problem of low film making efficiency when the existing cell smear device is used for preparing a sample smear.

Description

Cell smear device

Technical Field

The utility model relates to a cell smear device.

Background

The traditional cytological examination usually adopts smear made by a pap smear method, the smear made by the pap smear method has a large amount of overlapped cells, and the smear has a large amount of red blood cells, white blood cells, mucus, exfoliated necrotic tissues and the like, and a false negative rate of 2% -50% can occur during interpretation. In recent years, liquid-based thin layer cytology has become more and more popular.

The utility model discloses a cell smear device with an authorization notice number of CN106018030B, which comprises a film making bin, a glass slide and a film making bin base, wherein a filter cup is arranged in the film making bin, an annular flange is arranged at the upper end of the filter cup and is abutted against the upper end face of the film making bin, a filter screen is fixed at the lower end of the filter cup, a sealing ring is arranged below the film making bin, the glass slide is positioned above the film making bin base, and the film making bin is positioned above the glass slide and is clamped with the film making bin base in a rotary mounting manner so that the sealing ring is pressed between the glass slide and the film making bin to form sealing. When the cell smear device is used for preparing a sample smear, the sample density separating medium is poured into the smear making chamber until the liquid level is flush with the filter screen, then the sample solution with cells is dripped into the sample density separating medium through the filter screen, and the supernatant is poured out after standing, settling and separating to obtain the sample smear.

However, when the cell smear machine is used for preparing a sample smear, only one sample smear can be obtained at a time, and the smear making efficiency is low.

SUMMERY OF THE UTILITY MODEL

The utility model aims to provide a cell smear device, which is used for solving the problem of low film making efficiency when the existing cell smear device is used for preparing a sample smear.

The technical scheme of the cell smear device is as follows:

the cell smear device includes:

a tablet making bin base;

the slide making bin is detachably fixed on a slide making bin base, a filter cup is arranged in the slide making bin, the filter cup is used for filtering the sample solution with the cells, and a slide making bin opening for the sample solution with the cells to pass through is formed in the bottom of the slide making bin;

the glass slide is arranged on the film making bin base and is in sealing fit with the film making bin opening;

the film-making storehouse has two at least, is equipped with the isolation tank on the slide glass, and the notch of isolation tank and film-making storehouse mouth supply the sample solution of taking the cell relatively from the film-making storehouse entering isolation tank, and a film-making storehouse corresponds at least one isolation tank.

Has the advantages that: the cell smear device can simultaneously prepare sample smears containing more than two samples for observation by arranging more than two film making bins on the film making bin base, thereby improving the film making efficiency. In addition, the arrangement of the isolation grooves can isolate the samples and prevent the samples from interfering with each other.

Further, the isolation grooves are arranged at intervals in the length direction of the slide glass.

Has the advantages that: the arrangement utilizes the structural characteristics of the glass slide, and the layout is more reasonable.

Further, the isolation groove is a circular groove.

Has the advantages that: the isolation groove is simple in structure and convenient to process.

Furthermore, the sheet making bins correspond to the isolation grooves one by one.

Has the advantages that: the slide glass is simpler in structure and convenient to process due to the one-to-one correspondence of the slide making bins and the isolation grooves.

Further, the notch shape of the isolation groove is the same as the shape of the flaking bin opening.

Has the advantages that: the shape of the notch of the isolation groove is the same as that of the mouth of the flaking bin, and the butt joint of the two mouths is facilitated.

Further, the film making bin is multiple.

Has the advantages that: the film-making efficiency of sample smear can be improved more in the setting up of a plurality of film-making storehouses.

Furthermore, the slide making base is provided with an installation groove for installing the slide.

Has the advantages that: the glass slide is installed through the installation groove, and the operation is simple and rapid.

Furthermore, the mounting groove is a sliding groove, the sliding groove is provided with a glass slide loading opening for the slide to slide in along the extending direction of the slide, and the groove wall of the sliding groove, which is opposite to the glass slide loading opening, is used for being matched with the slide in a stopping way after the slide slides in place.

Has the advantages that: the mounting groove is simple in structure and convenient to process.

Further, a sealing ring is arranged at the bottom of the slide making bin, and when the slide making bin is in sealing fit with the glass slide, the sealing ring is positioned on the periphery of the notch of the isolation groove.

Has the advantages that: the sealing effect between the bottom of the slide making bin and the glass slide is enhanced by the arrangement of the sealing ring.

Furthermore, a clamping block is arranged on the slide making bin, a clamping groove clamped with the clamping block is arranged on the base of the slide making bin, adaptive wedge surfaces are arranged on the clamping block and the clamping groove, the clamping block and the clamping groove are wedged tightly by rotating the slide making bin, and the slide making bin moves towards the slide glass so as to be in sealing fit with the slide glass.

Has the advantages that: the fixing mode of the slide making bin is wedged tightly by the fixture block and the clamping groove, the operation is simple, the pressing effect of the slide making bin on the slide glass is better due to the fixing mode, and the sealing effect of the bottom of the slide making bin and the slide glass is better.

Drawings

FIG. 1 is a schematic diagram showing the structure of a first embodiment of the cell smear device of the present invention;

FIG. 2 is a schematic structural diagram of a first embodiment of the cell smear device of the present invention;

fig. 3 is a sectional view taken along the line a of fig. 2.

In the figure: 1. a tablet making bin base; 2. a glass slide; 3. a tablet making bin; 4. a filter cup; 5. an isolation trench; 6. a fixed block; 7. a bin body; 8. an annular flange; 9. a clamping block; 10. and (5) sealing rings.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the detailed description and specific examples, while indicating the preferred embodiment of the utility model, are intended for purposes of illustration only and are not intended to limit the scope of the utility model. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.

Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the utility model, as claimed, but is merely representative of selected embodiments of the utility model. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present invention without making any creative effort, shall fall within the protection scope of the present invention.

It is noted that relational terms such as "first" and "second," and the like, may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.

The features and properties of the present invention are described in further detail below with reference to examples.

The first embodiment of the cell smear device of the present invention:

as shown in fig. 1, 2 and 3, the cell smear device includes a slide making chamber base 1, a slide glass 2 on the slide making chamber base 1, and a slide making chamber 3 fixed on the slide making chamber base 1 and pressing the slide glass 2.

The slide making bin base 1 is integrally a cuboid, a mounting groove is formed in the slide making bin base 1, the slide glass 2 is placed in the mounting groove, in the embodiment, the mounting groove is a sliding groove, the sliding groove is provided with a slide glass loading opening into which the slide glass 2 slides along the extending direction of the slide glass 2, and the wall of the sliding groove, which is opposite to the slide glass loading opening, is used for being matched with the slide glass 2 in a blocking manner after the slide glass 2 slides in place. Be provided with buckle structure on the film-making storehouse base 1, buckle structure is used for solid film-making storehouse 3, and buckle structure includes two fixed

blocks

6, and 6 symmetrical arrangement of two fixed blocks all are equipped with the draw-in groove in the both sides of film-making storehouse base 1 in two fixed block 6 relative one sides, and two draw-in grooves extend along the length direction of film-making storehouse base 1, and the draw-in groove is the arc wall, and the relative tank bottom surface of two arc walls is the same circle.

As shown in fig. 2 and 3, there are three film making bins 3, which correspond to the fastening structures one by one and are fixed on the film making bin base 1 through the fastening structures, and the three film making bins 3 are arranged at intervals along the length direction of the film making bin base 1. The flaking storehouse 3 includes the storehouse body 7 of both ends open-ended cylinder, and the upper end opening of storehouse body 7 supplies the sample solution entering of taking the cell, and the lower extreme opening is for supplying the flaking storehouse mouth that the sample solution of taking the cell flows out. The internal portion of storehouse 7 is provided with filter cup 4, and filter cup 4 is big-end-up's both ends open-ended cylindric structure, and filter cup 4's upper end is equipped with annular flange 8, and the lower terminal surface of annular flange 8 is pressed at the up end of the storehouse body 7 so that filter cup 4 hangs in film making storehouse 3, and the opening part of the lower extreme of filter cup 4 is equipped with the filter screen. Be equipped with on the outer peripheral face of the lower part of film making storehouse 3 with two fixture blocks 9 of draw-in groove cooperation chucking, on two fixture block 9 symmetries set up the outer peripheral face of film making storehouse 3, especially, be equipped with the wedge surface of adaptation on fixture block 9 and the draw-in groove, the concrete expression does: in two draw-in grooves of buckle structure, highly according to its extending direction step-down setting between the upper and lower cell wall of a draw-in groove, the altitude variation between the upper and lower cell wall of another draw-in groove is opposite, correspondingly, highly along the setting of the gradual step-down of the circumference of film-making storehouse 3 between the upper and lower bottom surface of fixture block 9, make fixture block 9 and draw-in groove wedge tight through rotatory film-making storehouse 3. In addition, the bottom of the flaking bin 3 is provided with a sealing ring 10.

When using this device, install mounting groove with slide glass 2 earlier, later with the bottom surface and the 2 butts of slide glass of film-making storehouse 3, rotate film-making storehouse 3, make the fixture block 9 card of film-making storehouse 3 go into the draw-in groove, receive the extrusion at the in-process sealing washer 10 that rotates film-making storehouse 3, film-making storehouse 3 can receive the ascending reaction force of sealing washer 10 and make fixture block 9 and draw-in groove closely laminate, and then make film-making storehouse 3 fix on film-making storehouse base 1, at this moment, the sealing washer 10 of film-making storehouse 3 bottom hugs closely on slide glass 2, it is sealed to realize between the contact surface of film-making storehouse 3 and slide glass 2.

More specifically, the surface of slide 2 is equipped with isolation groove 5, and isolation groove 5 has three and with film-making storehouse 3 one-to-one. In the present embodiment, the isolation groove 5 is a circular groove, and particularly, when the flaking chamber 3 is fixed on the flaking chamber base 1, the sealing ring 10 at the bottom of the flaking chamber 3 is positioned at the periphery of the notch of the isolation groove 5.

When the cell smear device is used for manufacturing a sample smear, the sample density separating medium is poured into the smear making bin 3 until the liquid level is flush with the filter screen, the sample solution with cells is dripped into the sample density separating medium after the sample solution is filtered by the filter screen, and the supernatant is poured out after standing, settling and separating to obtain the sample smear. In this embodiment, a smear of samples containing three samples can be prepared simultaneously, and the three samples do not interfere with each other due to the provision of the isolation groove 5.

The second embodiment of the cell smear device of the present invention is different from the first embodiment described above in that the isolation groove is a rectangular groove. In other embodiments, the isolation slots may also be triangular or other shapes.

The third embodiment of the cell smear device of the present invention is different from the first embodiment described above in that the number of the film making chambers is two. In other embodiments, the number of tableting bins may be four, five or more.

The fourth embodiment of the cell smear device of the present invention is different from the first embodiment described above in that the mounting groove of the slide making chamber is a rectangular groove.

The fifth embodiment of the cell smear machine of the present invention is different from the first embodiment described above in that the film making bins are not in one-to-one correspondence with the isolation slots, and the number of the isolation slots is greater than that of the film making bins.

In the sixth embodiment of the cell smear device of the present invention, the sealing ring is located in the groove of the isolation groove, which is different from the first embodiment described above.

The seventh embodiment of the cell smear machine of the present invention is different from the first embodiment described above in that the outer circumferential surface of the slide making chamber is provided with external threads, and the external threads are in threaded connection with the threads arranged on the fixture block on the slide making chamber base so as to fix the slide making chamber on the slide making chamber base.

The above description is only a preferred embodiment of the present invention, and not intended to limit the present invention, the scope of the present invention is defined by the appended claims, and all structural changes that can be made by using the contents of the description and the drawings of the present invention are intended to be embraced therein.

Claims

1. A cell smear machine comprising:

a tablet making bin base (1);

the cell-carrying sample solution filtering device comprises a film making bin (3) which is detachably fixed on a film making bin base (1), wherein a filter cup (4) is arranged in the film making bin (3), the filter cup (4) is used for filtering the cell-carrying sample solution, and a film making bin opening for the cell-carrying sample solution to pass through is formed in the bottom of the film making bin (3);

the glass slide (2) is arranged on the film making bin base (1) and is in sealing fit with the film making bin opening;

the cell-carrying slide glass is characterized in that the number of the slide glass making bins (3) is at least two, the slide glass (2) is provided with an isolation groove (5), the notch of the isolation groove (5) and the opening of the slide glass making bin are opposite to each other so that sample solution with cells can enter the isolation groove (5) from the slide glass making bin (3), and one slide glass making bin (3) corresponds to at least one isolation groove (5).

2. A cell smear device according to claim 1 wherein the isolation slots (5) are spaced apart along the length of the slide (2).

3. A cell smear device according to claim 1 or 2 wherein the isolation slot (5) is a circular groove.

4. The cell smear machine according to claim 1 or 2, wherein the film making bins (3) correspond to the isolation slots (5) one by one.

5. A cell smear device according to claim 4 wherein the isolation slot (5) has a notch shape identical to the shape of the smear compartment opening.

6. The cell smear machine according to claim 1 or 2, wherein the film making chamber (3) is provided in plurality.

7. The cell smear machine according to claim 1 or 2, wherein the slide making chamber base (1) is provided with a mounting groove for mounting the slide (2).

8. The cell smear device according to claim 7, wherein the mounting groove is a sliding groove, the sliding groove is provided with a slide glass loading opening for the slide glass (2) to slide in along the extending direction of the slide glass (2), and the groove wall of the sliding groove opposite to the slide glass loading opening is used for being matched with the slide glass (2) in a stopping way after the slide glass (2) slides in place.

9. The cell smear device according to claim 1 or 2, wherein the bottom of the slide making chamber (3) is provided with a sealing ring (10), and when the slide making chamber (3) is matched with the slide glass (2) in a sealing way, the sealing ring (10) is positioned at the periphery of the notch of the isolation groove (5).

10. The cell smear machine according to claim 1 or 2, wherein the slide making chamber (3) is provided with a fixture block (9), the slide making chamber base (1) is provided with a clamping groove clamped with the fixture block (9), wherein the fixture block (9) and the clamping groove are provided with adaptive wedge surfaces, the fixture block (9) and the clamping groove are wedged tightly by rotating the slide making chamber (3), and the slide making chamber (3) moves towards the slide glass (2) so that the slide making chamber (3) is in sealing fit with the slide glass (2).