CN215866708U - Immunochromatographic reagent card - Google Patents
Immunochromatographic reagent card Download PDFInfo
- Publication number
- CN215866708U CN215866708U CN202121418128.1U CN202121418128U CN215866708U CN 215866708 U CN215866708 U CN 215866708U CN 202121418128 U CN202121418128 U CN 202121418128U CN 215866708 U CN215866708 U CN 215866708U
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- Prior art keywords
- overpressure
- strip
- reagent card
- preventing
- upper cover
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- 239000003153 chemical reaction reagent Substances 0.000 title claims abstract description 35
- 238000003317 immunochromatography Methods 0.000 claims abstract description 15
- 238000004587 chromatography analysis Methods 0.000 claims abstract description 14
- 230000002265 prevention Effects 0.000 claims abstract 2
- 238000003825 pressing Methods 0.000 claims description 19
- 239000007788 liquid Substances 0.000 claims description 18
- 238000003860 storage Methods 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 238000010521 absorption reaction Methods 0.000 claims description 6
- 238000005070 sampling Methods 0.000 claims description 2
- 238000001514 detection method Methods 0.000 abstract description 12
- 238000000034 method Methods 0.000 abstract description 9
- 238000004519 manufacturing process Methods 0.000 abstract description 5
- 230000002159 abnormal effect Effects 0.000 abstract description 3
- 239000012528 membrane Substances 0.000 description 6
- 239000011550 stock solution Substances 0.000 description 3
- 210000002700 urine Anatomy 0.000 description 3
- 239000000020 Nitrocellulose Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 229920001220 nitrocellulos Polymers 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 238000010924 continuous production Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model discloses an immunochromatography reagent card which comprises an upper cover and a lower cover, wherein a chromatography detection unit is arranged between the upper cover and the lower cover and comprises a test strip placing area for placing test strips, and overpressure prevention structures which are positioned between the upper cover and the lower cover and used for preventing the test strips from being excessively compressed are respectively arranged at two sides of the test strip placing area at intervals. According to the immunochromatography reagent card, the overpressure-preventing structures are respectively arranged on the two sides of the test strip placing area, so that the test strip can be prevented from being excessively pressed in the production and assembly processes of the reagent card, the abnormal condition of the chromatographic state of the reagent in the detection process can be avoided, and the detection accuracy and reliability are improved.
Description
Technical Field
The utility model belongs to the technical field of immunochromatography, and particularly relates to an immunochromatography reagent card.
Background
The principle of immunochromatography (immunochromatography) is that a specific antibody is firstly fixed in a certain zone of a nitrocellulose membrane, after one end of the dried nitrocellulose membrane is immersed in a sample (urine or serum), the sample moves forwards along the membrane due to capillary action, when the sample moves to a region where the antibody is fixed, a corresponding antigen in the sample is specifically bound with the antibody, and the region can show a certain color if the region is stained by immune colloidal gold or immune enzyme, so that specific immunodiagnosis is realized.
The immunochromatography technology has the advantages of high detection speed, simple operation, low cost and the like, and becomes a common technical means in detection of food safety, medical treatment and the like. However, in the existing production and assembly process of immunochromatography reagent cards, the card pressing machine of the continuous production line easily causes the upper cover and the lower cover of the reagent card to be pressed too tightly, thereby causing the abnormal reagent chromatography state during detection.
Disclosure of Invention
In view of the above, the present invention provides an immunochromatography reagent card capable of preventing an upper cover and a lower cover from being pressed too tightly during a production assembly process.
In order to achieve the purpose, the utility model provides the following technical scheme:
the utility model provides an immunochromatography reagent card, includes upper cover and lower cover, be equipped with chromatography detecting element between upper cover and the lower cover, chromatography detecting element places the district including the test paper strip that is used for placing the test paper strip, the both sides that the test paper strip placed the district are equipped with the interval respectively and are located be used for preventing that the test paper strip is by excessive anti-pressure structure who compresses tightly between upper cover and the lower cover.
Furthermore, two sides of the test strip placing area are respectively provided with at least two overpressure-preventing structures at intervals.
Furthermore, the overpressure-preventing structure comprises an upper overpressure-preventing strip and a lower overpressure-preventing strip which are correspondingly arranged on the upper cover and the lower cover respectively, and the upper overpressure-preventing strip and the lower overpressure-preventing strip which belong to the same overpressure-preventing structure are staggered after the upper cover and the lower cover are covered.
Further, the overpressure-preventing structure comprises at least two upper overpressure-preventing strips which are parallel to each other and at least two lower overpressure-preventing strips which are parallel to each other.
Furthermore, the upper anti-pressing strip and the lower anti-pressing strip which belong to the same anti-pressing structure are perpendicular to each other.
Further, chromatography detecting element is including being located the stock solution pond of the feed liquor end in district is placed to the test paper strip, the stock solution pond sets up cover down, cover on with the stock solution pond corresponds and is equipped with the application of sample hole.
Further, the sampling hole is in a water drop shape.
Furthermore, the upper cover is provided with an observation window corresponding to the middle position of the test strip placement area.
Furthermore, the upper cover is provided with air holes, and the air holes are positioned at the water absorption end of the test strip placement area.
Furthermore, the volume of the liquid storage tank is 70-300 muL.
The utility model has the beneficial effects that:
according to the immunochromatography reagent card, the overpressure-preventing structures are respectively arranged on the two sides of the test strip placing area, so that the test strip can be prevented from being excessively pressed in the production and assembly processes of the reagent card, the abnormal condition of the chromatographic state of the reagent in the detection process can be avoided, and the detection accuracy and reliability are improved.
Drawings
In order to make the object, technical scheme and beneficial effect of the utility model more clear, the utility model provides the following drawings for explanation:
FIG. 1 is a schematic structural diagram of an immunochromatographic reagent card according to an embodiment of the present invention;
FIG. 2 is a schematic structural view of the upper cover;
fig. 3 is a schematic structural view of the lower cover.
Description of reference numerals:
1-covering the upper cover; 2-lower cover; 3-a test strip placement area; 4, mounting a waterproof strip; 5-pressing the lower waterproof strip; 6-a liquid storage tank; 7-a sample addition hole; 8-an observation window; 9-air holes.
Detailed Description
The present invention is further described with reference to the following drawings and specific examples so that those skilled in the art can better understand the present invention and can practice the present invention, but the examples are not intended to limit the present invention.
FIG. 1 is a schematic structural diagram of an embodiment of the immunochromatographic reagent card of the present invention. The immunochromatography reagent card of this embodiment, including upper cover 1 and lower cover 2, be equipped with the chromatography detecting element between upper cover 1 and the lower cover 2, the chromatography detecting element places district 3 including the test paper strip that is used for placing the test paper strip, and the both sides that the district 3 was placed to the test paper strip are equipped with the anti-overvoltage structure that is used for preventing that the test paper strip from being excessively compressed tightly that is located between upper cover 1 and the lower cover 2 at the interval respectively. Specifically, the both sides that district 3 was placed to the test paper strip are separated respectively and are equipped with two at least anti-overvoltage structure, and the test paper strip of this embodiment is placed the both sides that district 3 was placed to the test paper strip and is separated respectively and be equipped with two and prevent the overvoltage structure, and this embodiment lies in the test paper strip and places district 3 with two of preventing that overvoltage structure lies in the both ends that the observation window 8 respectively with one side, can ensure that whole test paper strip can not all not compressed tightly by excessively.
Further, the excessive pressure structure of preventing of this embodiment is including corresponding the last strip 4 of preventing that sets up on upper cover 1 and lower cover 2 respectively and preventing down strip 5, belongs to same on preventing excessive pressure structure and prevents that strip 4 prevents down strip 5 prevents to close back crisscross each other at upper cover 1 and lower cover 2 lid, utilizes the last strip 4 of preventing pressing of crisscross each other and prevents down the limiting displacement between the strip 5, can avoid the test paper strip to be compressed tightly excessively. Preferably, prevent that excessive pressure structure includes that the at least two that are parallel to each other prevent pressing strip 4 and the at least two that are parallel to each other prevent pressing strip 5 down, prevent that excessive pressure structure of this embodiment includes that the two that are parallel to each other prevent pressing strip 4 and the two that are parallel to each other prevent pressing strip 5 down, prevent pressing strip 4 and many down on many and prevent pressing the mutual crisscross network structure of formation between the strip 5, can play spacing excessive effect of compressing tightly of preventing better. This embodiment belongs to the same on preventing excessive pressure structure and prevents pressing 4 and prevent pressing 5 between mutually perpendicular, and is concrete, prevents pressing 4 and test paper strip on and places the length direction of district 3 parallel, prevents pressing 5 and test paper strip down and places the length direction of district 3 perpendicular, as shown in fig. 2 and fig. 3.
Further, the chromatography detecting element of this embodiment is including the liquid storage tank 6 that is located the feed liquor end that test paper strip placed district 3, and liquid storage tank 6 sets up on lower cover 2, and upper cover 1 is gone up and is equipped with application of sample hole 7 with liquid storage tank 6 correspondence, and application of sample hole 7 is used for dropwise add detection liquid sample in liquid storage tank 6, like serum/plasma, whole blood, excrement and urine diluent, urine etc. the application of sample hole 7 of this embodiment is the water droplet form. The upper cover 1 of this embodiment is equipped with observation window 8 with the middle part position correspondence of test paper strip placing area 3, is equipped with bleeder vent 9 on the upper cover 1, and bleeder vent 9 is located the water absorption end of test paper strip placing area 3, and observation window 8 is located between application of sample hole 7 and bleeder vent 9. The air holes 9 play a role in balancing the internal and external air pressures of the reagent card in the detection process, and the influence of the internal and external pressure imbalance on the chromatographic detection of the reagent is avoided. By arranging the air holes 9 at the water absorption end of the test strip placement area 3, the water absorption end can be used for drying quickly, so that the influence of liquid at the water absorption end on the reagent background caused by the backflow to the membrane surface (because the membrane surface is directly exposed in the air and dries quickly) is prevented, the reagent result observation time is prolonged, and the background influence is reduced.
The volume of the liquid storage tank 6 of the embodiment is 70-300 μ L, in the immunochromatography detection process, when the sample adding amount of the liquid sample is less, the chromatography is incomplete or the direct chromatography fails, when the sample adding amount of the liquid sample is excessive, the liquid sample overflows sample adding holes or forms a sample washing, and overflows the membrane surface of the observation area, so that the result interpretation is affected. In the embodiment, the volume of the liquid storage tank 6 is compatible with 70-300 muL, and the compatible volume range is larger.
The immunochromatography reagent card of this embodiment, through respectively placing the both sides in the district at the test paper strip and setting up respectively and prevent excessive pressure structure, so, in reagent card production assembling process, can avoid the test paper strip to be compressed tightly excessively to can avoid detecting the unusual condition of time measuring reagent chromatography state, improve and detect accuracy and reliability.
The above-mentioned embodiments are merely preferred embodiments for fully illustrating the present invention, and the scope of the present invention is not limited thereto. The equivalent substitution or change made by the technical personnel in the technical field on the basis of the utility model is all within the protection scope of the utility model. The protection scope of the utility model is subject to the claims.
Claims (10)
1. The utility model provides an immunochromatography reagent card, includes upper cover (1) and lower cover (2), be equipped with chromatography detecting element between upper cover (1) and lower cover (2), chromatography detecting element places district (3), its characterized in that including the test paper strip that is used for placing the test paper strip: and two sides of the test strip placing area (3) are respectively provided with an overpressure prevention structure at intervals between the upper cover (1) and the lower cover (2) for preventing the test strip from being excessively compressed.
2. The immunochromatographic reagent card of claim 1, wherein: the two sides of the test strip placing area (3) are respectively provided with at least two overpressure-preventing structures at intervals.
3. The immunochromatographic reagent card according to claim 1 or 2, wherein: the overpressure-preventing structure comprises an upper overpressure-preventing strip (4) and a lower overpressure-preventing strip (5) which are correspondingly arranged on the upper cover (1) and the lower cover (2) respectively, and the upper overpressure-preventing strip (4) and the lower overpressure-preventing strip (5) belong to the same overpressure-preventing structure and are staggered with each other after the upper cover (1) and the lower cover (2) are covered.
4. The immunochromatographic reagent card of claim 3, wherein: the overpressure-proof structure comprises at least two upper overpressure-proof strips (4) which are parallel to each other and at least two lower overpressure-proof strips (5) which are parallel to each other.
5. The immunochromatographic reagent card of claim 3, wherein: the upper anti-pressing strip (4) and the lower anti-pressing strip (5) belonging to the same anti-pressing structure are vertical to each other.
6. The immunochromatographic reagent card of claim 1, wherein: the chromatography detecting unit comprises a liquid storage tank (6) which is located at the liquid inlet end of the test strip placing area (3), the liquid storage tank (6) is arranged on the lower cover (2), and a sample adding hole (7) is correspondingly arranged on the upper cover (1) and the liquid storage tank (6).
7. The immunochromatographic reagent card of claim 6, wherein: the sampling hole (7) is in a water drop shape.
8. The immunochromatographic reagent card of claim 6, wherein: and an observation window (8) is correspondingly arranged on the upper cover (1) and in the middle of the test strip placement area (3).
9. The immunochromatographic reagent card of claim 8, wherein: the upper cover (1) is provided with air holes (9), and the air holes (9) are located at the water absorption end of the test strip placement area (3).
10. The immunochromatographic reagent card according to any one of claims 6 to 9, wherein: the volume of the liquid storage tank (6) is 70-300 muL.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121418128.1U CN215866708U (en) | 2021-06-24 | 2021-06-24 | Immunochromatographic reagent card |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121418128.1U CN215866708U (en) | 2021-06-24 | 2021-06-24 | Immunochromatographic reagent card |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215866708U true CN215866708U (en) | 2022-02-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202121418128.1U Active CN215866708U (en) | 2021-06-24 | 2021-06-24 | Immunochromatographic reagent card |
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| Country | Link |
|---|---|
| CN (1) | CN215866708U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023179215A1 (en) * | 2022-03-24 | 2023-09-28 | 艾康生物技术(杭州)有限公司 | Immunoassay device |
-
2021
- 2021-06-24 CN CN202121418128.1U patent/CN215866708U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023179215A1 (en) * | 2022-03-24 | 2023-09-28 | 艾康生物技术(杭州)有限公司 | Immunoassay device |
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