CN215866388U - Constant temperature fluorescence detection device for nucleic acid sample - Google Patents

Abstract

The utility model provides a constant-temperature fluorescence detection device for a nucleic acid sample, which relates to the technical field of sample detection and comprises a shell, an insulation can, a detection box, a heating assembly and a clamping assembly, wherein the top of the shell is rotatably connected with a cover through a hinge, the surface of the cover is provided with an observation window, the insulation can is fixedly arranged in the shell, water is arranged in the insulation can, the detection box is arranged in the insulation can, the front of the shell is fixedly provided with a control panel, the heating assembly is arranged between the shell and the detection box and used for heating the detection box, and the clamping assembly is arranged between the cover and the shell and used for clamping and fixing the cover. This kind of equipment uses through the cooperation of heater, first heat pipe and insulation can, can make the detection case thermally equivalent rise in temperature, uses through the cooperation of second heat pipe, hair-dryer, air intake and air outlet, advances the heat exchange to the insulation can to reach the cooling effect.

Description

Constant temperature fluorescence detection device for nucleic acid sample

Technical Field

The utility model relates to the technical field of sample detection, in particular to a constant-temperature fluorescence detection device for a nucleic acid sample.

Background

In the process of detecting and analyzing nucleic acid samples, operation is mostly carried out in a fluorescence detection mode, and in the actual operation, different temperature effects need to be ensured at different stages, and meanwhile, a constant temperature detection device needs to be used for changing the temperature within a certain temperature range.

But current check out test set generally all is that direct to detect the bottom of the case portion heats, heats inhomogeneous, and local intensification influences the detection data soon, and cools down then directly bloies with the hair-dryer to the detection case for the temperature of detection case descends soon, and temperature fluctuation is big, is unfavorable for the regulation and control to the temperature, causes the stability decline of sample itself.

SUMMERY OF THE UTILITY MODEL

The utility model aims to solve the defects in the background art and provides a constant-temperature fluorescence detection device for a nucleic acid sample.

In order to achieve the above object, the present invention provides the following technical solution, a constant temperature fluorescence detection apparatus for nucleic acid samples, comprising a housing, a heat-preserving box, a detection box, a heating component and a clamping component;

the top of the shell is rotatably connected with a cover through a hinge, the surface of the cover is provided with an observation window, the interior of the shell is fixedly provided with an insulation can, the interior of the insulation can is provided with a detection box, and the front of the shell is fixedly provided with a control panel;

a heating assembly is arranged between the shell and the detection box and used for heating the detection box;

and a clamping component is arranged between the cover and the shell and used for clamping and fixing the cover.

Further, heating element includes heater, first heat pipe and second heat pipe, the inside fixed mounting of shell has the heater, just heater and control panel electric connection, the first heat pipe of heater top fixedly connected with, first heat pipe one side fixedly connected with second heat pipe, the inside water that is provided with of insulation can.

Furthermore, the first heat conduction pipe penetrates through the heat insulation box and is located inside the heat insulation box, the first heat conduction pipe is wound outside the detection box from bottom to top, and the second heat conduction pipe is located outside the heat insulation box.

Further, the block subassembly is including inlaying the piece, inlaying groove, fixture block and draw-in groove, a plurality of pieces of inlaying of lid bottom fixedly connected with, a plurality of grooves of inlaying have been seted up at the shell top, inlay piece one side and seted up the adjustment tank, the inside fixture block that is provided with of adjustment tank, and the one end protrusion in the adjustment tank of fixture block, the draw-in groove has been seted up to the shell inside, just the draw-in groove switches on with inlaying the groove mutually.

Furthermore, the inside reset spring that is provided with of adjustment tank, just the one end that the adjustment tank was kept away from to reset spring is connected with the fixture block, the inside press block that is provided with of draw-in groove, press the equal fixedly connected with fixed block of upper and lower surface of press block, the shifting chute has all been seted up to draw-in groove inner wall top and bottom, just the inside spring post that is provided with of shifting chute, the one end of spring post is connected with the fixed block, the one end protrusion in the shell surface of the fixture block is kept away from to the press block.

Furthermore, a pressing plate is arranged at the bottom of the cover, and a compression spring is arranged between the pressing plate and the cover.

Further, the inside fixed mounting of shell has the hair-dryer, the air intake has been seted up to shell one side, the air outlet has been seted up to shell one side, hair-dryer and control panel electric connection.

Furthermore, a display screen is arranged on the surface of the control panel, a temperature sensor is fixedly mounted in the heat insulation box, and a signal output end of the temperature sensor is in signal connection with a signal receiving end of the display screen.

The utility model provides a constant-temperature fluorescence detection device for a nucleic acid sample, which has the following beneficial effects:

1. the utility model has the advantages of, when needs heat up the detection case, through control panel, heater, first heat pipe and water for the detection case is heated evenly intensification at the uniform velocity, and when first heat pipe stopped the intensification heating, also can heat the detection case through water and keep warm, makes the detection case be in under homothermal state, avoids the local intensification of detection case to lead to sample detection data to appear the deviation too fast.

2. Secondly, when needs cool down the insulation can, through control panel, hair-dryer, second heat pipe, air intake and air outlet for gaseous second heat pipe carries out the heat exchange, and then makes the temperature of first heat pipe descend and absorb the inside heat of insulation can, makes the inside temperature of insulation can descend, makes the inside air cycle that forms of shell 1 simultaneously, and even heat dissipation is stably cooled down.

Drawings

Fig. 1 is a schematic view of the overall structure of the present invention.

Fig. 2 is a sectional view of the overall structure of the present invention.

Fig. 3 is a schematic view of a first heat conducting tube structure according to the present invention.

Fig. 4 is a schematic diagram of a pressing plate structure according to the present invention.

Fig. 5 is an enlarged view of the utility model at a in fig. 2.

In FIGS. 1-5: 1. a housing; 101. a cover; 102. an observation window; 103. a compression spring; 104. a pressing plate; 105. a control panel; 2. embedding a block; 201. embedding the groove; 202. a return spring; 203. a clamping block; 204. a card slot; 205. a pressing block; 206. a fixed block; 207. a spring post; 3. a heater; 301. a first heat conductive pipe; 302. a second heat conductive pipe; 4. a heat preservation box; 401. a temperature sensor; 5. a detection box; 6. a blower; 601. an air inlet; 602. and (7) air outlet.

Detailed Description

Example (b):

referring to figures 1-5 of the drawings,

the constant-temperature fluorescence detection device for the nucleic acid sample provided by the embodiment comprises a shell 1, an insulation box 4, a detection box 5, a heating assembly and a clamping assembly;

the top of the shell 1 is rotatably connected with a cover 101 through a hinge, the surface of the cover 101 is provided with an observation window 102, the heat preservation box 4 is fixedly arranged inside the shell 1, the detection box 5 is arranged inside the heat preservation box 4, and the front of the shell 1 is fixedly provided with a control panel 105;

a heating component is arranged between the shell 1 and the detection box 5 and is used for heating the detection box 5;

a clamping component is arranged between the cover 101 and the housing 1 for clamping and fixing the cover 101.

The observation window 102 is made of organic glass, the organic glass has good light transmittance and impact resistance, the detection condition of the sample can be checked through the observation window 102 when the sample is detected, and the organic glass cannot be broken into fragments after being punctured by the fragments, so that surrounding workers can be prevented from being injured;

for the observation window 102, the tempered glass with better impact resistance should be selected, and then the organic glass with poorer impact resistance is selected, but the tempered glass is usually thicker, the light transmittance is only about 88%, the organic glass is not only light and thin, but also the light transmittance can reach about 92%, so the organic glass is more suitable for manufacturing the observation window 102 relative to the tempered glass.

Further, the heating assembly comprises a heater 3, a first heat pipe 301 and a second heat pipe 302, the heater 3 is fixedly installed inside the housing 1, the heater 3 is electrically connected with the control panel 105, the top of the heater 3 is fixedly connected with the first heat pipe 301, one side of the first heat pipe 301 is fixedly connected with the second heat pipe 302, water is arranged inside the heat preservation box 4, when the temperature of the detection box 5 needs to be raised, the heater 3 is started through the control panel 105, the heater 3 further raises the temperature of the first heat pipe 301 for heating, the first heat pipe 301 raises the temperature of the water inside the heat preservation box 4 for heating, further, the detection box 5 is uniformly heated and uniformly at a constant temperature through the first heat pipe 301 and the water, when the first heat pipe 301 stops raising the temperature for heating, the detection box 5 can be heated and preserved through the water, and the detection box 5 is in a constant temperature state, the sample detection data deviation caused by the local temperature rise of the detection box 5 is avoided.

Further, the first heat pipe 301 penetrates the heat insulation box 4 and is located inside the heat insulation box 4, the first heat pipe 301 is wound outside the detection box 5 from bottom to top, and the second heat pipe 302 is located outside the heat insulation box 4, so that the first heat pipe 301 can uniformly heat the detection box 5.

Further, the clamping assembly comprises an insert block 2, an insert groove 201, a clamping block 203 and a clamping groove 204, the bottom of the cover 101 is fixedly connected with a plurality of insert blocks 2, the top of the housing 1 is provided with a plurality of insert grooves 201, one side of the insert block 2 is provided with an adjusting groove, the clamping block 203 is arranged in the adjusting groove, one end of the clamping block 203 protrudes out of the adjusting groove, the clamping groove 204 is arranged in the housing 1, the clamping groove 204 is communicated with the insert groove 201, when the cover 101 needs to be closed, the cover 101 is closed through hinge rotation, the insert block 2 is just inserted into the insert groove 201 at the moment, the clamping block 203 is extruded by the insert groove 201 and is collected into the adjusting groove, the reset spring 202 is extruded by the clamping block 203 to generate elastic deformation to generate elastic force, when the cover 101 is completely closed, the adjusting groove is opposite to the clamping groove 204, so that the clamping block 203 rebounds under the elastic force of the reset spring 202 and is inserted into the clamping groove 204, so that the cover 101 is snap-coupled to the housing 1 via the latch 203 and the latch groove 204.

Further, a return spring 202 is arranged in the adjusting groove, one end of the return spring 202, which is far away from the adjusting groove, is connected with a clamping block 203, a pressing block 205 is arranged in the clamping groove 204, the upper surface and the lower surface of the pressing block 205 are fixedly connected with fixed blocks 206, the top and the bottom of the inner wall of the clamping groove 204 are respectively provided with a moving groove, one side of the fixed block 206 is fixedly connected with a spring post 207, one end of the spring post 207, which is far away from the fixed block 206, is connected with the inner wall of the moving groove, one end of the pressing block 205, which is far away from the clamping block 203, protrudes out of the outer surface of the shell 1, when the cover 101 needs to be opened, the pressing block 205 is pressed to move towards the clamping block 203 and push the clamping block 203 out of the clamping groove 204, at the moment, the pressing block 205 drives the fixed block 206 to move, the spring post 207 is pressed to generate elastic deformation, so that the clamping block 203 is separated from the clamping groove 204, and then the cover 101 is opened through hinge rotation, the pressing block 205 is then released, causing the pressing block 205 and the fixed block 206 to spring back to their original positions under the spring force of the spring post 207.

Furthermore, a plurality of compression springs 103 are arranged at the bottom of the cover 101, a pressing plate 104 is fixedly connected to one end, away from the cover 101, of each compression spring 103, the pressing plate 104 is tightly attached to the top of the detection box 5, and when the cover 101 is closed, the detection box 5 is pressed inside the insulation box 4 through the pressing plate 104 and the compression springs 103, so that a pressing and fixing effect is achieved on the detection box 5.

Further, the inside fixed mounting of shell 1 has hair-dryer 6, air intake 601 has been seted up to shell 1 one side, air outlet 602 has been seted up to shell 1 one side, hair-dryer 6 and control panel 105 electric connection, when needs cool down insulation can 4, start hair-dryer 6 through control panel 105, make hair-dryer 6 blow near gas to second heat pipe 302, make gas carry out the heat exchange to second heat pipe 302, and then make the temperature of first heat pipe 301 descend, and absorb the inside heat of insulation can 4, make the inside temperature of insulation can 4 descend, near the production negative pressure of hair-dryer 6 simultaneously, inhale inside shell 1 with external gas through air intake 601, and discharge the gas after will absorbing the heat through air outlet 602, form an air cycle.

Further, control panel 105 surface is provided with the display screen, the inside fixed mounting of insulation can 4 has temperature-sensing ware 401, and temperature-sensing ware 401's signal output part and the signal receiving terminal signal connection of display screen, the signal output part through temperature-sensing ware 401 sends the signal receiving terminal of display screen with the inside real-time temperature data of insulation can 4, and show temperature data through the display screen, so that the staff regulates and control the inside temperature of insulation can 4, guarantee the inside sample detection environment and the temperature of detection case 5.

When the cover 101 is required to be opened, the pressing block 205 is pressed to move the pressing block 205 towards the latch 203 and push the latch 203 out of the slot 204, at the moment, the pressing block 205 drives the fixing block 206 to move, the spring post 207 is pressed to generate elastic deformation to generate elastic force, the latch 203 is separated from the slot 204, then the cover 101 is opened through hinge rotation, then the pressing block 205 is loosened, the pressing block 205 and the fixing block 206 rebound to the original position under the action of the elastic force of the spring post 207, then a sample is placed in the detection box 5, then the cover 101 is closed through hinge rotation, at the moment, the embedding block 2 is just inserted into the embedding slot 201, at the same time, the latch 203 is extruded by the embedding slot 201 and is collected into the adjusting slot, at the moment, the reset spring 202 is pressed by the latch 203 to generate elastic deformation to generate elastic force, when the cover 101 is completely closed, the adjusting groove is opposite to the clamping groove 204, so that the clamping block 203 rebounds under the action of the elastic force of the return spring 202 and is inserted into the clamping groove 204, the cover 101 is connected with the shell 1 in a clamping manner through the clamping block 203 and the clamping groove 204, meanwhile, the detection box 5 is pressed inside the insulation box 4 through the pressing plate 104 and the compression spring 103, a pressing and fixing effect is achieved on the detection box 5, then when the detection box 5 needs to be heated, the heater 3 is started through the control panel 105, the heater 3 heats the first heat conduction pipe 301, the first heat conduction pipe 301 heats water inside the insulation box 4, the detection box 5 is heated uniformly through the first heat conduction pipe 301 and at a constant speed, and when the first heat conduction pipe 301 stops heating, the detection box 5 can be heated and insulated through the water, so that the detection box 5 is in a constant temperature state, avoid detection case 5 local intensification to lead to the sample to detect data to appear the deviation too fast, when needs cool down insulation can 4, start hair-dryer 6 through control panel 105, make hair-dryer 6 blow near gas to second heat pipe 302, make gas carry out the heat exchange to second heat pipe 302, and then make the temperature of first heat pipe 301 descend, and absorb the inside heat of insulation can 4, make the inside temperature of insulation can 4 descend, near hair-dryer 6 produces the negative pressure simultaneously, inhale inside the shell 1 with external gas through air intake 601, and discharge the gas after will absorbing the heat through air outlet 602, form an air cycle, can be fixed to the constant temperature and the block of lid 101 of guarantee detection ring border through above structure.

Claims (8)

1. A constant-temperature fluorescence detection device for a nucleic acid sample is characterized by comprising a shell, an insulation box, a detection box, a heating assembly and a clamping assembly;

the top of the shell is rotatably connected with a cover through a hinge, the surface of the cover is provided with an observation window, the interior of the shell is fixedly provided with an insulation can, the interior of the insulation can is provided with a detection box, and the front of the shell is fixedly provided with a control panel;

a heating assembly is arranged between the shell and the detection box and used for heating the detection box;

and a clamping component is arranged between the cover and the shell and used for clamping and fixing the cover.

2. The constant-temperature fluorescence detection device for the nucleic acid sample according to claim 1, wherein the heating assembly comprises a heater, a first heat conduction pipe and a second heat conduction pipe, the heater is fixedly installed inside the housing and electrically connected with the control panel, the first heat conduction pipe is fixedly connected to the top of the heater, the second heat conduction pipe is fixedly connected to one side of the first heat conduction pipe, and water is arranged inside the heat preservation box.

3. The apparatus according to claim 2, wherein the first heat pipe penetrates the thermal container and is disposed inside the thermal container, the first heat pipe is wound from bottom to top around the exterior of the thermal container, and the second heat pipe is disposed outside the thermal container.

4. The constant-temperature fluorescence detection device for the nucleic acid sample according to claim 1, wherein the clamping assembly comprises a plurality of insert blocks, insert grooves, clamping blocks and clamping grooves, the bottom of the cover is fixedly connected with the plurality of insert blocks, the top of the housing is provided with a plurality of insert grooves, one side of each insert block is provided with an adjusting groove, each adjusting groove is internally provided with a clamping block, one end of each clamping block protrudes out of each adjusting groove, each clamping groove is formed in the housing, and the clamping grooves are communicated with the insert grooves.

5. The constant-temperature fluorescence detection device for nucleic acid samples according to claim 4, wherein a return spring is disposed inside the adjustment groove, one end of the return spring away from the adjustment groove is connected to the fixture block, a pressing block is disposed inside the clamping groove, fixed blocks are fixedly connected to the upper and lower surfaces of the pressing block, moving grooves are formed in the top and bottom of the inner wall of the clamping groove, a spring post is disposed inside the moving grooves, one end of the spring post is connected to the fixed block, and one end of the pressing block away from the fixture block protrudes out of the outer surface of the housing.

6. The isothermal fluorescence detection device for nucleic acid samples according to claim 1, wherein a pressing plate is provided at the bottom of the cap, and a compression spring is provided between the pressing plate and the cap.

7. The constant-temperature fluorescence detection device for nucleic acid samples according to claim 1, wherein a blower is fixedly installed inside the housing, an air inlet is formed in one side of the housing, an air outlet is formed in one side of the housing, and the blower is electrically connected with the control panel.

8. The isothermal fluorescence detection device for nucleic acid samples according to claim 1, wherein a display screen is disposed on the surface of the control panel, a temperature sensor is fixedly installed inside the incubator, and a signal output end of the temperature sensor is in signal connection with a signal receiving end of the display screen.

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