CN215856011U

CN215856011U - Cell disruption device with good stability

Info

Publication number: CN215856011U
Application number: CN202121591353.5U
Authority: CN
Inventors: �田润; 宋乐元
Original assignee: Chengdu Zen Bioscience Co ltd
Current assignee: Chengdu Zen Bioscience Co ltd
Priority date: 2021-07-14
Filing date: 2021-07-14
Publication date: 2022-02-18
Anticipated expiration: 2031-07-14

Abstract

The utility model discloses a cell disruption device with good stability, and relates to the technical field of cell disruption. The cell breaking device comprises a plurality of breaking tanks which are distributed in a straight line, breaking mechanisms for breaking cells are arranged in the breaking tanks, shaking mechanisms for enabling the breaking tanks to move in a reciprocating mode are arranged at the bottoms of the breaking tanks, and stabilizing mechanisms for guiding and limiting the shaking mechanisms are arranged on the outer side surfaces, opposite to the breaking tanks, of the breaking tanks corresponding to the positions of two ends of the straight line. The cell crushing efficiency can be improved through the breaking mechanism and the shaking mechanism, the shaking mechanism is simple in structure, low in cost and low in operation difficulty, the device can be more stable by utilizing the stabilizing mechanism, and the stability of the crushing tank in reciprocating movement along with the shaking mechanism is improved, so that the cell crushing is facilitated.

Description

Cell disruption device with good stability

Technical Field

The utility model belongs to the technical field of cell disruption, and particularly relates to a cell disruption device with good stability.

Background

The cell disruption technology is a technology for destroying cell membranes and cell walls by using external force to release target product components from cell contents, when a certain protein is disrupted, separated and purified, the protein is firstly released from tissues or cells and is kept in an original natural state without losing activity, so that the tissues and the cells are disrupted by adopting a proper method, the cell disruption difficulty is different for different organisms or tissues of different parts of the same organism, the use method is different, for example, the cell membranes of animal organs are fragile and easy to disrupt, and plants and microorganisms have firmer cell walls consisting of cellulose and hemicellulose.

The existing cell disruption device has certain defects: the crushing efficiency of current cell disruption device to the cell is often more general, and partial device is taken and is utilized agitating unit to carry out the breakage to the cell and remove the measure that improves crushing effect to agitating unit repeatedly again, and its structure is comparatively complicated and stability is relatively poor when doing so to bring certain inconvenience for the breakage of cell.

In order to solve the problems, the utility model provides a cell disruption device with good stability.

SUMMERY OF THE UTILITY MODEL

The utility model aims to provide a cell crushing device with good stability, which solves the problems that the existing cell crushing device has general crushing efficiency, and partial devices adopt measures of crushing cells by using a stirring device and then repeatedly moving the stirring device to improve the crushing effect, so that the structure is complex and the stability is poor.

In order to solve the technical problems, the utility model is realized by the following technical scheme:

the utility model relates to a cell crushing device with good stability, which comprises a plurality of crushing tanks which are distributed linearly, wherein breaking mechanisms for breaking cells are arranged in the crushing tanks, shaking mechanisms for enabling the crushing tanks to move in a reciprocating manner are arranged at the bottoms of the crushing tanks, and stabilizing mechanisms for guiding and limiting the shaking mechanisms are arranged on the opposite outer side surfaces of the crushing tanks corresponding to the positions of two ends of the straight line.

Further, the breaking mechanism comprises: rotate the motor, the dwang, helical blade, connecting rod and broken ball, the top surface fixed mounting of broken jar has the rotation motor, the output that rotates the motor runs through broken jar's top surface and fixedly connected with dwang through the shaft coupling, many evenly distributed's of dwang top-down fixedly connected with connecting rod, still the welding has helical blade on the dwang, be provided with a plurality of broken balls in the broken jar, it drives dwang and helical blade and connecting rod to rotate motor drive, make the cell rotate and collide with broken ball, reach broken effect.

Further, the shaking mechanism includes: carry the thing board, the spout, the cylinder, movable block and mounting panel, broken jar's bottom is provided with carries the thing board, broken jar fixed connection is at the top surface of movable block, carry the top surface of thing board and seted up the spout, and movable block and spout sliding connection, carry the equal fixedly connected with mounting panel of the front and back both sides face of thing board, the top surface fixed mounting of mounting panel has the cylinder, the output of cylinder run through carry the lateral wall of thing board and with the side fixed connection of movable block, the cylinder drives movable block and broken jar reciprocating motion in the spout, and then make this device better to the crushing effect of cell.

Further, the stabilizing mechanism includes: riser, guide bar and connecting block, the equal fixedly connected with riser of top surface of two mounting panels, fixedly connected with guide bar between the riser, the equal fixedly connected with connecting block of relative lateral surface of broken jar under the straight line both ends position corresponds, and the connecting block is run through by the guide bar to with guide bar sliding connection, stabilizing mean's effect can make broken jar reciprocating motion's in-process remain stable in the spout, thereby make this device more stable, and then be favorable to the breakage of cell.

Further, two slide bars of fixedly connected with in the spout, the slide bar run through the movable block and with movable block sliding connection, connecting rod fixedly connected with cross stirring piece, broken jar interior bottom surface fixedly connected with trickles the material platform, logical groove has been seted up to broken jar side, and it is connected with the turnover door to lead to the inslot through the hinge rotation, be provided with the keying structure between turnover door and the broken jar, the slide bar can improve the stability of movable block when removing in the spout, trickles the material platform and can make the ejection of compact of broken jar more convenient with the turnover door.

The utility model has the following beneficial effects:

the cell crushing efficiency can be improved through the breaking mechanism and the shaking mechanism, the shaking mechanism is simple in structure, low in cost and low in operation difficulty, the device can be more stable by utilizing the stabilizing mechanism, and the stability of the crushing tank in reciprocating movement along with the shaking mechanism is improved, so that the cell crushing is facilitated.

Of course, it is not necessary for any product in which the utility model is practiced to achieve all of the above-described advantages at the same time.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic structural view of a stabilizing mechanism according to the present invention;

FIG. 3 is an enlarged view taken at A in FIG. 1;

fig. 4 is a schematic view of the breaking mechanism of the present invention;

FIG. 5 is a schematic structural view of a cross stirring block according to the present invention.

In the drawings, the components represented by the respective reference numerals are listed below: 1. a crushing tank; 2. a loading plate; 3. mounting a plate; 4. a cylinder; 5. a vertical plate; 6. a guide bar; 7. connecting blocks; 8. rotating the motor; 9. a chute; 10. a slide bar; 11. rotating the rod; 12. a helical blade; 13. a cross-shaped stirring block; 14. a connecting rod; 15. crushing a ball; 16. turning over the door; 17. a material dripping table; 18. a movable block.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, it is to be understood that the terms "upper", "middle", "outer", "inner", and the like, indicate orientations or positional relationships, are used for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the referenced components or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.

Referring to fig. 1-5, the present invention is a cell disruption device with good stability, including a plurality of disruption tanks 1 distributed linearly, each of the plurality of disruption tanks 1 having a breaking mechanism for breaking cells, the breaking mechanism including: rotate motor 8, dwang 11, helical blade 12, connecting rod 14 and broken ball 15, the top surface fixed mounting of broken jar 1 has rotation motor 8, the output of rotating motor 8 passes through broken jar 1's top surface and fixedly connected with dwang 11 through the shaft coupling, many evenly distributed's of dwang 11 top-down fixedly connected with connecting rod 14, it has helical blade 12 still to weld on dwang 11, be provided with a plurality of broken balls 15 in broken jar 1, it drives dwang 11 and helical blade 12 and connecting rod 14 to rotate motor 8 drive, make the cell rotate and collide with broken ball 15, reach broken effect, broken jar 1's bottom is provided with the mechanism that rocks that is used for making broken jar 1 carry out reciprocating motion, it includes to rock the mechanism: carry thing board 2, spout 9, cylinder 4, movable block 18 and mounting panel 3, the bottom of broken jar 1 is provided with carries

thing board

2, 1 fixed connection of broken jar is at the top surface of movable block 18, carry the top surface of thing board 2 and seted up spout 9, and movable block 18 and spout 9 sliding connection, carry the equal fixedly connected with mounting panel 3 of the front and back both sides face of thing board 2, the top surface fixed mounting of mounting panel 3 has cylinder 4, the output of cylinder 4 run through carry thing board 2 the lateral wall and with the side fixed connection of movable block 18, cylinder 4 drives movable block 18 and broken jar 1 reciprocating motion in spout 9, and then make this device better to the crushing effect of cell, and the relative lateral surface of the broken jar 1 that sharp both ends position corresponds down all sets up useful spacing stabilizing mean that leads to rocking mechanism, stabilizing mean includes: riser 5, guide bar 6 and connecting block 7, the equal fixedly connected with riser 5 of the top surface of two mounting panels 3, fixedly connected with guide bar 6 between riser 5, the equal fixedly connected with connecting block 7 of relative lateral surface of broken jar 1 under the straight line both ends position corresponds, and connecting block 7 is run through by guide bar 6, and with 6 sliding connection of guide bar, stabilizing mean's effect can make broken jar 1 reciprocating motion's in spout 9 in-process remain stable, thereby make this device more stable, and then be favorable to the breakage of cell.

Two slide bars 10 of fixedly connected with in the spout 9, slide bar 10 run through movable block 18 and with 18 sliding connection of movable block, connecting rod 14 fixedly connected with cross stirring piece 13, broken jar 1's interior bottom surface fixedly connected with trickles material platform 17, logical groove has been seted up to broken jar 1's side, and it is connected with turnover door 16 to lead to the inslot through the hinge rotation, be provided with the keying structure between turnover door 16 and the broken jar 1, slide bar 10 can improve the stability of movable block 18 when removing in spout 9, it is more convenient to trickle the ejection of compact of 1 of broken jar that material platform 17 and turnover door 16 can make.

As shown in FIGS. 1 to 5, the rotating motor 8 is SF-J37 KW, and this embodiment is a method for using a cell disruption device with good stability: the frequency parameter of cylinder 4 has been adjusted in advance, cylinder 4 drives movable block 18 and broken jar 1 reciprocating motion in spout 9, the while drive rotates motor 8, it drives dwang 11 and helical blade 12 and connecting rod 14 rotation to rotate the drive of motor 8, make the cell rotate and collide with broken ball 15, stabilizing mean's effect can make broken jar 1 reciprocating motion's in spout 9 in-process remain stable, thereby make this device more stable, and then be favorable to the breakage of cell.

In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

The preferred embodiments of the utility model disclosed above are intended to be illustrative only. The preferred embodiments are not intended to be exhaustive or to limit the utility model to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the utility model and the practical application, to thereby enable others skilled in the art to best utilize the utility model. The utility model is limited only by the claims and their full scope and equivalents.

Claims

1. The utility model provides a good cell disruption device of stability, includes a plurality of straight line distribution's broken jar (1), its characterized in that: the cell breaking device is characterized in that breaking mechanisms used for breaking cells are arranged in the crushing tanks (1), shaking mechanisms used for enabling the crushing tanks (1) to move in a reciprocating mode are arranged at the bottoms of the crushing tanks (1), and stabilizing mechanisms used for guiding and limiting the shaking mechanisms are arranged on the opposite outer side surfaces of the crushing tanks (1) corresponding to the positions of the two ends of the straight line.

2. A stable cell disruption device according to claim 1, wherein said breaking mechanism comprises: rotate motor (8), dwang (11), helical blade (12), connecting rod (14) and broken ball (15), the top surface fixed mounting of broken jar (1) has rotation motor (8), the output of rotating motor (8) runs through the top surface and the fixedly connected with dwang (11) of broken jar (1) through the shaft coupling, many evenly distributed's of dwang (11) top-down fixedly connected with connecting rod (14), it has helical blade (12) still to weld on dwang (11), be provided with a plurality of broken balls (15) in broken jar (1).

3. The device for cell disruption with good stability according to claim 1, wherein said shaking mechanism comprises: carry thing board (2), spout (9), cylinder (4), movable block (18) and mounting panel (3), the bottom of broken jar (1) is provided with carries thing board (2), broken jar (1) fixed connection is at the top surface of movable block (18), spout (9) have been seted up to the top surface of carrying thing board (2), and movable block (18) and spout (9) sliding connection, carry the equal fixedly connected with mounting panel (3) of the front and back both sides face of thing board (2), the top surface fixed mounting of mounting panel (3) has cylinder (4), the output of cylinder (4) run through carry the lateral wall of thing board (2) and with the side fixed connection of movable block (18).

4. A stable cell disruptor as claimed in claim 3, wherein the stabilising means comprises: riser (5), guide bar (6) and connecting block (7), the equal fixedly connected with riser (5) of top surface of two mounting panels (3), fixedly connected with guide bar (6) between riser (5), the equal fixedly connected with connecting block (7) of relative lateral surface of broken jar (1) under the straight line both ends position corresponds, and connecting block (7) are run through by guide bar (6) to with guide bar (6) sliding connection.

5. The cell disruption device with good stability as claimed in claim 3, wherein two sliding rods (10) are fixedly connected in the sliding groove (9), and the sliding rods (10) penetrate through the movable block (18) and are connected with the movable block (18) in a sliding manner.

6. A stable cell disruption device according to claim 2, wherein said connecting rod (14) is fixedly connected with a cross stirring block (13).

7. The cell disruption device with good stability as claimed in claim 1, wherein a material dripping table (17) is fixedly connected to the inner bottom surface of the disruption tank (1), a through groove is formed in the side surface of the disruption tank (1), a turning door (16) is rotatably connected to the through groove through a hinge, and a lock structure is arranged between the turning door (16) and the disruption tank (1).