CN215855052U - Small-size liquid filling machine of high accuracy and filling equipment - Google Patents

Small-size liquid filling machine of high accuracy and filling equipment Download PDF

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Publication number
CN215855052U
CN215855052U CN202122086915.7U CN202122086915U CN215855052U CN 215855052 U CN215855052 U CN 215855052U CN 202122086915 U CN202122086915 U CN 202122086915U CN 215855052 U CN215855052 U CN 215855052U
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precision
pipettor
chuck
filling
filling machine
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CN202122086915.7U
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黄挺
张恒
秦叶鹏
同炳桓
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Xi'an Biolab Biotechnology Co ltd
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Xi'an Biolab Biotechnology Co ltd
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Abstract

The embodiment of the utility model provides a high-precision small filling machine and filling equipment, and relates to the technical field of medical instruments. The high-precision small filling machine provided by the embodiment of the utility model comprises a rack, a liquid transfer device and a high-precision plunger pump. The rack is provided with a placing area for placing the reaction cups and a storing area for storing the reagent to be filled. The high-precision plunger pump is connected with the liquid transfer device, so that the liquid transfer device is driven to suck and discharge liquid through the high-precision plunger pump. Pipettor and frame swing joint to make the pipettor place the region and deposit the switching position between the region, when the pipettor is located and deposits regional position department, the pipettor imbibition under the effect of high accuracy plunger pump, when the pipettor is located and places regional position department, the pipettor is in reagent filling to the reaction cup under the effect of high accuracy plunger pump, so realize the high accuracy filling to little volume reagent through high accuracy plunger pump and pipettor, the filling is effectual, the precision is high.

Description

Small-size liquid filling machine of high accuracy and filling equipment
Technical Field
The utility model relates to the technical field of medical appliances, in particular to a high-precision small filling machine and filling equipment.
Background
In the medical device industry, the filling of reagents is essential. At present, the filling of large doses of reagents is mostly carried out by manual filling, since the precision requirements are not very high.
However, for filling a small dosage of reagent in microliter level for precise laboratory machine detection, if the reagent is filled manually, the method has the disadvantages of large error, tedious operation, slow filling speed and the like, and if the filling precision is not high, the final detection result is inaccurate in the reagent using process.
SUMMERY OF THE UTILITY MODEL
Objects of the present invention include, for example, providing a high precision, compact filling machine and filling equipment that enables high precision filling of small doses of reagents.
Embodiments of the utility model may be implemented as follows:
the embodiment of the utility model provides a high-precision small filling machine, which is used for filling reaction cups and comprises: the rack is provided with a placing area for placing the reaction cup and a storing area for storing a reagent to be filled; a pipettor movably connected to the rack to switch positions of the pipettor between the placement area and the storage area; and the high-precision plunger pump is connected with the liquid transfer device and is used for driving the liquid transfer device to suck and discharge liquid.
Optionally, the rack includes a base and a chuck slidably disposed on the base, and the placement area and the storage area are disposed on the chuck; the pipettor is connected to the base to effect positional switching of the pipettor between the placement region and the storage region by movement of the chuck relative to the base.
Optionally, the chuck is provided with a clamping groove, the clamping groove is used for accommodating a reaction cup holder for placing the reaction cup, and an opening is arranged on the side surface of the clamping groove, so that the reaction cup holder can enter and exit the clamping groove.
Optionally, the rack further includes a reagent cup disposed at one side of the card slot along a sliding direction of the card chuck, and the reagent cup is used for storing a reagent to be filled so as to form the storage area at the reagent cup.
Optionally, the number of the pipettes is multiple, the number of the high-precision plunger pumps is multiple, and the pipettes and the high-precision plunger pumps are arranged in a one-to-one correspondence manner; the number of the reagent cups is multiple, and the pipettors and the reagent cups are arranged in a one-to-one correspondence mode.
Optionally, the opening is provided with a guide surface for guiding the reaction cup holder into the clamping groove.
Optionally, the rack further includes a frame body fixedly connected to the base, the high-precision small-sized filling machine further includes a working arm in up-and-down sliding fit with the frame body, and the pipettor is connected to the working arm so as to move up and down relative to the chuck under the driving of the working arm.
Optionally, the high-precision small-sized filling machine further comprises a driving structure, and the driving structure is connected with the chuck to drive the chuck to slide relative to the base.
Optionally, the driving structure includes a first driving motor and a belt transmission structure, and the belt transmission structure is in transmission connection with the first driving motor to operate under the driving of the first driving motor; the chuck is provided with a connecting plate, and the connecting plate is fixedly connected with a belt of the belt transmission structure.
The embodiment of the utility model also provides filling equipment. The filling equipment comprises the high-precision small filling machine.
The high-precision small filling machine and the filling equipment provided by the embodiment of the utility model have the beneficial effects that:
the embodiment of the utility model provides a high-precision small filling machine for filling reaction cups, which comprises a rack, a liquid transfer device and a high-precision plunger pump. The rack is provided with a placing area for placing the reaction cups and a storing area for storing the reagent to be filled. The high-precision plunger pump is connected with the liquid transfer device, so that the liquid transfer device is driven to suck and discharge liquid through the high-precision plunger pump. Pipettor and frame swing joint to make the pipettor place the region and deposit the switching position between the region, when the pipettor is located and deposits regional position department, the pipettor imbibition under the effect of high accuracy plunger pump, when the pipettor is located and places regional position department, the pipettor is in reagent filling to the reaction cup under the effect of high accuracy plunger pump, so realize the high accuracy filling to little volume reagent through high accuracy plunger pump and pipettor, the filling is effectual, the precision is high.
The embodiment of the utility model also provides filling equipment which comprises the high-precision small filling machine. Because this filling equipment includes foretell small-size liquid filling machine of high accuracy, consequently also have and to realize the high accuracy filling of little volume reagent, the filling is effectual, the high beneficial effect of precision.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
Fig. 1 is a schematic structural diagram of a filling apparatus provided in an embodiment of the present invention in a first view;
fig. 2 is a schematic structural diagram of a filling apparatus provided in an embodiment of the present invention in a second viewing angle.
Icon: 10-filling equipment; 100-high precision small filling machine; 110-a rack; 111-a base; 112-a slide rail; 113-a chuck; 114-a card slot; 115-reagent cup; 116-a frame body; 117-a guide rail; 118-a connecting plate; 121-a pipette; 122-high precision plunger pump; 123-a working arm; 124-a second drive motor; 125-a transmission member; 130-a drive structure; 131-a first drive motor; 132-a drive pulley; 133-a driven pulley; 134-a belt; 211-power switch; 212-a host; 21-reaction cup holder; 22-reaction cup.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the utility model, as claimed, but is merely representative of selected embodiments of the utility model. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.
In the description of the present invention, it should be noted that if the terms "upper", "lower", "inside", "outside", etc. are used for indicating the orientation or positional relationship based on the orientation or positional relationship shown in the drawings or the orientation or positional relationship which is usually placed when the utility model is used, it is only for convenience of describing the present invention and simplifying the description, but it is not necessary to indicate or imply that the device or element referred to must have a specific orientation, be constructed in a specific orientation and be operated, and thus, it should not be construed as limiting the present invention.
Furthermore, the appearances of the terms "first," "second," and the like, if any, are used solely to distinguish one from another and are not to be construed as indicating or implying relative importance.
It should be noted that the features of the embodiments of the present invention may be combined with each other without conflict.
Fig. 1 is a schematic structural diagram of a filling apparatus 10 according to the present embodiment in a first viewing angle. Referring to fig. 1, the present embodiment provides a high-precision small-sized filling machine 100, and accordingly, a filling apparatus 10 is provided.
The filling apparatus 10 includes a high-precision small-sized filling machine 100, and the filling apparatus 10 further includes a host 212, wherein a power supply and an MCU (micro controller Unit) are provided in the host 212, and the host 212 is electrically connected to the high-precision small-sized filling machine 100, so as to supply power to and control each electrical appliance in the high-precision small-sized filling machine 100.
The high precision, small form factor filler 100 includes a rack 110, a pipette 121, and a high precision plunger pump 122. The rack 110 has a placement area for placing the cuvette 22 and a storage area for storing reagents to be filled. The high-precision plunger pump 122 is connected to the pipette 121, and the pipette 121 is driven to aspirate and discharge liquid by the high-precision plunger pump 122. The pipettor 121 is movably connected to the frame 110, so that the pipettor 121 is switched between the placement area and the storage area, when the pipettor 121 is located at the storage area, the pipettor 121 sucks liquid under the action of the high-precision plunger pump 122, and when the pipettor 121 is located at the placement area, the pipettor 121 fills the reagent into the reaction cup 22 under the action of the high-precision plunger pump 122.
The pipettor 121 is a tool that moves liquid from an original container to another container in a range of two, which enables high precision transfer of any volume of reagent in the range of 5ul to 500 ul.
The high-precision mini-filler 100 provided in this embodiment is further described below:
fig. 2 is a schematic structural diagram of the filling apparatus 10 provided in this embodiment in a second viewing angle. Referring to fig. 1 and fig. 2, in the present embodiment, the frame 110 includes a base 111 and a chuck 113 slidably disposed on the base 111, and the placing area and the storing area are both disposed on the chuck 113. The pipetter 121 is connected to the base 111 to enable the pipetter 121 to switch the position of the pipetter 121 between the placement area and the storage area by movement of the chuck 113 relative to the base 111.
Specifically, the base 111 is provided with a slide rail 112, and the bottom of the chuck 113 is provided with a slide groove (not shown) slidably engaged with the slide rail 112, so as to realize the sliding of the chuck 113 relative to the base 111.
It should be noted that, in the present embodiment, the chuck 113 is configured to be slidably engaged with the base 111, so that the pipette 121 is switched between the placement area and the corresponding position of the storage area by sliding the chuck 113 relative to the base 111 (as shown in fig. 1, the pipette 121 approximately corresponds to the position of the storage area), it can be understood that, in other embodiments, the chuck 113 may be configured to be fixedly connected with the base 111, and the pipette 121 may be configured to be horizontally slidable relative to the base 111, so that the position of the pipette 121 is switched between the placement area and the storage area.
Further, the high-precision small-sized filling machine 100 further includes a driving mechanism 130, and the driving mechanism 130 is connected to the chuck 113 to drive the chuck 113 to slide relative to the base 111. Specifically, the driving structure 130 includes a first driving motor 131 and a belt 134 transmission structure, and the belt 134 transmission structure includes a belt 134, a driving pulley 132 and a driven pulley 133.
The driving pulley 132 is connected to the first driving motor 131, the driving pulley 132 and the driven pulley 133 are disposed on the base 111 at intervals along the sliding direction of the chuck 113, and the belt 134 is simultaneously sleeved on the driving pulley 132 and the driven pulley 133, so that the driving pulley 132 drives the belt 134 and the driven pulley 133 to rotate under the driving of the first driving motor 131, and the portion of the belt 134 between the driving pulley 132 and the driven pulley 133 translates relative to the base 111. The chuck 113 is provided with a connecting plate 118 at one side, and the connecting plate 118 is fixedly connected with the belt 134, so as to slide relative to the base 111 under the driving of the belt 134.
It should be noted that the specific structure of the driving mechanism 130 is not limited herein, and it should be understood that in other embodiments, components such as an air cylinder, an oil cylinder, etc. may be used to drive the chuck 113 to slide according to requirements.
In this embodiment, the chuck 113 has a slot 114, and the slot 114 is used to accommodate the reaction cup holder 21 for placing the reaction cup 22, so the area where the slot 114 is located can be regarded as the placing area of the rack 110, and the side surface of the slot 114 has an opening through which the reaction cup holder 21 can enter and exit the slot 114. Specifically, the chuck 113 is substantially square, the engaging groove 114 is formed by recessing the upper top surface of the chuck 113 downward, and along the sliding direction of the chuck 113, one side of the engaging groove 114 is a storage area, and the other side of the engaging groove 114 forms an opening, so that the reaction cup holder 21 enters and exits the engaging groove 114 from the opening along the sliding direction of the chuck 113.
The reaction cup holder 21 is substantially square and is adapted to the slot 114, and a handle is disposed at one end of the reaction cup holder 21, and when the reaction cup holder 21 is received in the slot 114, the handle extends out of the slot 114 from the opening, so that the handle can be held to operate the reaction cup holder 21. The upper end of the reaction cup holder 21 is provided with a plurality of holes for accommodating the reaction cups 22, in the embodiment, twenty-four holes are formed in the reaction cup holder 21, so that twenty-four reaction cups 22 can be placed at a time, and the twenty-four reaction cups 22 can be filled.
Further, the opening of the slot 114 is provided with a guide surface for guiding the reaction cup holder 21 into the slot 114. Specifically, the opposite sides of the side opening of the card slot 114 have guide surfaces, respectively, and the distance between the two guide surfaces decreases in the direction into the card slot 114, in other words, the opening can also be regarded as a space defined by the two guide surfaces. Optionally, the guide surface is a ramp.
Further, the rack 110 further comprises reagent cups 115 arranged at one side of the card slots 114 in the sliding direction of the cartridges 113, the reagent cups 115 being used for storing reagents to be filled to form a storage area at the reagent cups 115. Specifically, the chuck 113 is provided with a mounting hole for receiving the reagent cup 115, and the mounting hole is located on a side of the card slot 114 away from the side opening.
Further, the number of the reagent cups 115 is plural, the number of the pipettors 121 is also plural, and the plural pipettors 121 are provided in one-to-one correspondence with the plural reagent cups 115. Correspondingly, the number of the high-precision plunger pumps 122 is also multiple, and the multiple high-precision plunger pumps 122 and the multiple pipettors 121 are arranged in a one-to-one correspondence manner, so that the liquid sucking and discharging operation requirements of the multiple pipettors 121 are met. Specifically, the number of reagent cups 115 is two, two reagent cups 115 are disposed in the width direction of the cartridge 113, and accordingly, the number of pipettes 121 is also two. Accordingly, the number of the high-precision plunger pumps 122 is also set to be plural. Twenty-four holes for accommodating the reaction cups 22 on the reaction cup holder 21 are arranged in two rows, so that each pipette 121 is arranged corresponding to one row of reaction cups 22, and the filling operation of one row of reaction cups 22 is completed. It will be appreciated that in other embodiments, the number of pipettes 121, as well as the reagent cups 115 and high precision plunger pumps 122, may be set as desired.
Referring to fig. 1 and fig. 2, in the present embodiment, the rack 110 further includes a frame body 116 fixedly connected to the base 111, the high-precision small-sized filling machine 100 further includes a working arm 123 vertically sliding-fitted to the frame body 116, and the pipette 121 is connected to the working arm 123, so as to slide vertically relative to the chuck 113 under the driving of the working arm 123. Specifically, the frame body 116 and the sliding rail 112 are distributed on both sides of the belt 134, and the lower end of the frame body 116 is fixedly connected to the base 111. A guide rail 117 is provided at the upper end of the frame body 116, one end of the working arm 123 is slidably engaged with the guide rail 117, and the other end of the working arm 123 extends outward to fix the pipette 121, and at this time, the pipette 121 is located at the upper side of the sliding path of the chuck 113.
The high-precision small-sized filling machine 100 further includes a second driving motor 124 and a transmission member 125, the second driving motor 124 is connected to the transmission member 125, and the upper end of the transmission member 125 is connected to the working arm 123, so that the transmission member 125 drives the working arm 123 to slide up and down relative to the frame 116.
According to the high-precision small-sized filling machine 100 provided by the embodiment, the working principle of the high-precision small-sized filling machine 100 is as follows:
empty reaction cups 22 are first placed in the holes of the reaction cup holder 21 in sequence, then the reaction cup holder 21 is snapped into the chuck 113 by holding the handle, and the reagent to be filled is added to the reagent cup 115, in exchange for a clean pipette 121. Then, the high-precision small-sized filling machine 100 is turned on by the power switch 211, and the suction amount of the pipette 121 is set according to the capacity of the cuvette 22.
Then, a filling process is started under the control of the host 212, in this process, the chuck 113 slides along the slide rail 112 in a forward direction (from right to left in the view angle shown in fig. 2) under the action of the driving structure 130 until the position of the pipette 121 corresponds to the reagent cup 115, then the second driving motor 124 drives the pipette 121 to move down for reagent suction, the pipette 121 moves up after suction, and then the driving structure 130 drives the chuck 113 to slide in a reverse direction (from left to right in the view angle shown in fig. 2) until the pipette 121 corresponds to one row of reaction cups 22, and fills the reaction cups 22, and after this filling is completed, the above process is repeated until all the reaction cups 22 on the chuck 113 are completely filled.
The high-precision small filling machine 100 provided by the embodiment at least has the following advantages:
the high-precision small filling machine 100 provided by the embodiment of the utility model can quickly and efficiently fill a plurality of reaction cups with reagents of any volume within the range of 5-500ul, and has the advantages of small volume, simple operation, high automation degree, high filling speed and the like.
The present embodiment also provides a filling apparatus 10 comprising the high precision mini-filler 100 described above. Since the filling apparatus 10 includes the high-precision small-sized filling machine 100 described above, there are also all the advantageous effects of the high-precision small-sized filling machine 100.
The above description is only for the specific embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.

Claims (10)

1. A high accuracy small-size liquid filling machine for filling reaction cup, its characterized in that, high accuracy small-size liquid filling machine includes:
the rack is provided with a placing area for placing the reaction cup and a storing area for storing a reagent to be filled;
a pipettor movably connected to the rack to switch positions of the pipettor between the placement area and the storage area; and
and the high-precision plunger pump is connected with the liquid transfer device and is used for driving the liquid transfer device to suck and discharge liquid.
2. A high precision, small form factor filler as set forth in claim 1 wherein said frame includes a base and a chuck slidably disposed on said base, said placement area and said storage area being disposed on said chuck; the pipettor is connected to the base to effect positional switching of the pipettor between the placement region and the storage region by movement of the chuck relative to the base.
3. A high precision small size filling machine as claimed in claim 2, wherein said chuck has a slot for receiving a reaction cup holder for placing said reaction cup, and the side of said slot is provided with an opening for said reaction cup holder to enter and exit said slot.
4. A high precision small size filling machine as defined in claim 3, characterized in that said rack further comprises reagent cups arranged at one side of said card slots in the sliding direction of said cartridge, said reagent cups being adapted to store reagents to be filled to form said storage areas at said reagent cups.
5. A high-precision small filling machine as claimed in claim 4, wherein the number of said pipettes is plural, the number of said high-precision plunger pumps is plural, and a plurality of said pipettes and a plurality of said high-precision plunger pumps are arranged in one-to-one correspondence; the number of the reagent cups is multiple, and the pipettors and the reagent cups are arranged in a one-to-one correspondence mode.
6. A high precision mini-filler as in claim 3 wherein the opening is provided with guide surfaces for guiding the reaction cup holder into the card slot.
7. A high precision mini-filler as in claim 2 wherein the frame further comprises a frame fixedly attached to the base, the high precision mini-filler further comprising a work arm slidably engaged with the frame up and down, the pipette being attached to the work arm for movement up and down relative to the chuck upon actuation of the work arm.
8. A high precision, small form factor filler as recited in claim 2, further comprising a drive mechanism coupled to the chuck for sliding the chuck relative to the base.
9. A high precision small size filling machine as defined in claim 8 wherein said drive structure includes a first drive motor and a belt drive structure drivingly connected to said first drive motor for operation under the drive of said first drive motor; the chuck is provided with a connecting plate, and the connecting plate is fixedly connected with a belt of the belt transmission structure.
10. A filling plant, characterized in that it comprises a high-precision mini-filler according to any of claims 1 to 9.
CN202122086915.7U 2021-08-31 2021-08-31 Small-size liquid filling machine of high accuracy and filling equipment Active CN215855052U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202122086915.7U CN215855052U (en) 2021-08-31 2021-08-31 Small-size liquid filling machine of high accuracy and filling equipment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202122086915.7U CN215855052U (en) 2021-08-31 2021-08-31 Small-size liquid filling machine of high accuracy and filling equipment

Publications (1)

Publication Number Publication Date
CN215855052U true CN215855052U (en) 2022-02-18

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202122086915.7U Active CN215855052U (en) 2021-08-31 2021-08-31 Small-size liquid filling machine of high accuracy and filling equipment

Country Status (1)

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CN (1) CN215855052U (en)

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