CN215839000U

CN215839000U - Mouse intestinal sensitivity experimental device

Info

Publication number: CN215839000U
Application number: CN202121836065.1U
Authority: CN
Inventors: 李建新; 林允
Original assignee: Wenzhou Peoples Hospital
Current assignee: Wenzhou Peoples Hospital
Priority date: 2021-08-06
Filing date: 2021-08-06
Publication date: 2022-02-18
Anticipated expiration: 2031-08-06

Abstract

The utility model discloses a rat intestinal sensitivity experiment device which adopts the technical scheme that the device comprises a mounting seat, wherein an inflator pump is mounted on the mounting seat, the front end of the inflator pump is connected with an inflation tube, and one end of the inflation tube is connected with an inflation ball. The utility model has the following beneficial effects: one end of the inflation tube and the uninflated inflation ball are inserted into the intestinal tract of the experimental mouse, the inflation tube inflates and expands the inflation ball, and then rectal dilatation experiments can be carried out on the mouse, so that the sensitivity of the intestinal tract of the mouse can be measured.

Description

Mouse intestinal sensitivity experimental device

Technical Field

The utility model relates to medical experimental equipment, in particular to a mouse intestinal sensitivity experimental device.

Background

The animal is a good experimental model which can simulate human behavior and physiological function. Visceral hypersensitivity is one of the important pathophysiological features of irritable bowel syndrome. In basic research, animals are commonly used to establish a model for irritable bowel syndrome. Only by detecting the intestinal sensitivity of the animal, whether the animal model is successfully made can be judged, and the effectiveness of the model is verified. The rodent intestinal sensitivity is tested by performing rectal dilation test and scoring by evaluating abdominal contractile reflex behavior to determine the animal intestinal sensitivity.

SUMMERY OF THE UTILITY MODEL

Aiming at the defects in the prior art, the utility model aims to provide a rat intestinal sensitivity experiment device, and the test equipment can be used for carrying out rectal distension experiments on rats to determine the rat intestinal sensitivity.

In order to achieve the purpose, the utility model provides the following technical scheme: a mouse intestinal sensitivity experiment device comprises a mounting seat, wherein an inflator pump is mounted on the mounting seat, the front end of the inflator pump is connected with an inflation tube, and one end of the inflation tube is connected with an inflation ball.

The utility model is further configured to: still sliding connection has the piston in the gas cylinder to be provided with the scale on the barrel body, the piston is connected with the pole of aerifing, is provided with the push pedal on the pole of aerifing.

The utility model is further configured to: the face, facing the inflator, of the push plate is fixedly connected with a limiting rod, a sliding sleeve is arranged in front of the limiting rod, the sliding sleeve is sleeved on the inflator and is in sliding connection with the inflator, a positioning hole is formed in the sliding sleeve, a fastening screw is connected with the positioning hole in a threaded mode, and one end of the fastening screw penetrates through the positioning hole and is abutted to the inflator.

The utility model is further configured to: the inflator pump is detachably connected to the mounting seat.

The utility model is further configured to: install electric telescopic handle on the mount pad, electric telescopic handle's one end can be dismantled and connect on the push pedal.

The utility model is further configured to: the tube body of the inflation tube close to the inflation ball is also provided with a sensor for monitoring the intestinal tract and the viscera, and the sensor is electrically connected with the monitor

The utility model is further configured to: the inflation tube is provided with a three-way reversing valve, the three-way reversing valve is provided with an exhaust hole and an electric commutator, the monitor is provided with a control center, and the control center is electrically connected with the electric commutator.

In conclusion, the utility model has the following beneficial effects: one end of the inflation tube and the uninflated inflation ball are inserted into the intestinal tract of the experimental mouse, the inflation tube inflates and expands the inflation ball, and then rectal dilatation experiments can be carried out on the mouse, so that the sensitivity of the intestinal tract of the mouse can be measured.

Drawings

FIG. 1 is a schematic view of the connection structure of a murine intestinal sensitivity testing device;

fig. 2 is a schematic view of a connection structure of the gas filling pipe.

Detailed Description

The present invention will be described in further detail with reference to the accompanying drawings and examples. In which like parts are designated by like reference numerals. It should be noted that the terms "front," "back," "left," "right," "upper" and "lower" used in the following description refer to directions in the drawings, and the terms "bottom" and "top," "inner" and "outer" refer to directions toward and away from, respectively, the geometric center of a particular component.

Referring to fig. 1-2, a rat intestinal sensitivity experiment device comprises a mounting seat 1, wherein an inflator 2 is mounted on the mounting seat 1, the front end of the inflator 2 is connected with an inflation tube 3, and one end of the inflation tube 3 is connected with an inflation ball 4.

Through the scheme, one end of the inflation tube 3 and the uninflated inflation ball 4 are inserted into the intestinal tract of the experimental mouse, the inflation tube 3 inflates and expands the inflation ball 4 through the inflation cylinder 2, and then rectal dilatation experiments can be performed on the mouse, so that the sensitivity of the intestinal tract of the mouse can be measured.

As a modified specific implementation mode, a piston 21 is further connected in the inflator 2 in a sliding manner, a graduated scale is arranged on the inflator body, an inflation rod 22 is connected to the piston 21, and a push plate 23 is arranged on the inflation rod 22.

Through the scheme, the inflator pump 2 is made of transparent materials, and the air inflow is controlled through the cooperation of the graduated scale and the piston 21, so that the corresponding air inflow is accurately pushed.

As a modified specific embodiment, a limiting rod 24 is fixedly connected to a face of the push plate 23 facing the inflator 2, a sliding sleeve 6 is disposed in front of the limiting rod 24, the sliding sleeve 6 is sleeved on the inflator 2 to be slidably connected with the inflator 2, and is provided with a positioning hole 61, the positioning hole 61 is in threaded connection with a fastening screw 62, and one end of the fastening screw 62 passes through the positioning hole 61 to abut against the inflator 2.

Through above-mentioned scheme, remove sliding sleeve 6 according to the scale, rotate fastening screw 62, it is fixed with sliding sleeve 6, when admitting air, promote push pedal 23, gag lever post 24 pushes up on sliding sleeve 6 to the propulsive piston 21 position of accurate control, with the air input that the accurate estimation is gone into, with the inflation size and the atmospheric pressure of estimation balloon 34, many times or gradient experiment, and then the cooperation monitoring data obtains more accurate experimental result.

As a modified embodiment, the inflator 2 is detachably connected to the mounting base 1.

By the above scheme, the air cylinder 32 can be detachably replaced to raise the upper limit of the air intake amount and the upper limit of the air intake speed.

As a modified specific embodiment, the mounting seat 1 is provided with an electric telescopic rod 12, and one end of the electric telescopic rod 12 is detachably connected to the push plate 23.

Through the scheme, the electric telescopic rod 12 accurately controls the feeding air quantity, and the accuracy of an experiment is ensured.

As a modified specific embodiment, a sensor 5 for monitoring the intestinal tract and the internal organs is further arranged on the tube body of the inflation tube 3 close to the inflation ball 4, and the sensor 5 is electrically connected with a monitor 11.

By the scheme, the monitor 11 reads the intestinal tract and viscera data monitored by the sensor 5.

As a modified specific embodiment, a three-way reversing valve 31 is installed on the inflation tube 3, an exhaust hole 32 and an electric commutator 33 are arranged on the three-way reversing valve 31, a control center 13 is arranged on the monitor 11, and the control center 13 is electrically connected with the electric commutator 33.

Through the scheme, the control center 13 controls the electric commutator 33 to adjust the three-way reversing valve 31 so as to realize sealing, air inlet and air outlet, and the use is convenient.

The above description is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiments, and all technical solutions belonging to the idea of the present invention belong to the protection scope of the present invention. It should be noted that modifications and embellishments within the scope of the utility model may occur to those skilled in the art without departing from the principle of the utility model, and are considered to be within the scope of the utility model.

Claims

1. A mouse intestinal sensitivity experimental device is characterized in that: the inflatable air-filled inflator comprises a mounting seat (1), an inflator (2) is mounted on the mounting seat (1), an inflation tube (3) is connected to the front end of the inflator (2), and an inflation ball (4) is connected to one end of the inflation tube (3).

2. The murine intestinal sensitivity test device of claim 1, wherein: still sliding connection has piston (21) in inflator pump (2) to be provided with the scale on the barrel, piston (21) are connected with and inflate pole (22), be provided with push pedal (23) on inflating pole (22).

3. The murine intestinal sensitivity test device of claim 2, wherein: fixedly connected with gag lever post (24) on push pedal (23) face towards inflator pump (2), the place ahead of gag lever post (24) is provided with sliding sleeve (6), sliding sleeve (6) cover is established on inflator pump (2) to with inflator pump (2) sliding connection, and be provided with locating hole (61), locating hole (61) threaded connection has fastening screw (62), locating hole (61) are passed to the one end of fastening screw (62) for the butt is on inflator pump (2).

4. The murine intestinal sensitivity test device of claim 3, wherein: the inflator pump (2) is detachably connected to the mounting seat (1).

5. The murine intestinal sensitivity test device of claim 4, wherein: install electric telescopic handle (12) on mount pad (1), the connection can be dismantled on push pedal (23) to the one end of electric telescopic handle (12).

6. The murine intestinal sensitivity test device of claim 1, wherein: the inflatable tube (3) is close to the tube body of the inflatable ball (4) and is further provided with a sensor (5) used for monitoring the intestinal tract and the viscera, and the sensor (5) is electrically connected with a monitor (11).

7. The murine intestinal sensitivity test device of claim 6, wherein: install three-way switching-over valve (31) on gas tube (3), be provided with exhaust hole (32) and electric commutator (33) on three-way switching-over valve (31), be provided with control center (13) on watch-dog (11), control center (13) are connected with electric commutator (33) electricity.