CN215739214U - Spring ring for photothermal treatment of hemangioma and vascular malformation - Google Patents
Spring ring for photothermal treatment of hemangioma and vascular malformation Download PDFInfo
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- CN215739214U CN215739214U CN202121939314.XU CN202121939314U CN215739214U CN 215739214 U CN215739214 U CN 215739214U CN 202121939314 U CN202121939314 U CN 202121939314U CN 215739214 U CN215739214 U CN 215739214U
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Abstract
The utility model discloses a spring ring for photothermal treatment of hemangioma and vascular malformation, which comprises a spring ring body and a connecting mechanism, wherein the connecting mechanism is arranged outside the spring ring body, the connecting mechanism comprises a conveying catheter, and the left end of the spring ring body penetrates through the conveying catheter and extends to the interior of the conveying catheter to be contacted with the inner wall of the conveying catheter. According to the utility model, through the mutual matching of the base layer, the photo-thermal nano material coating and the conveying conduit, after the spring ring body is implanted into an aneurysm or a malformed blood vessel, the photo-thermal nano material of the surface coating can generate a heat effect under the irradiation of in-vitro near infrared light, vascular endothelial cells are damaged, local thrombosis is promoted in a controllable manner, and the blood flow in the diseased blood vessel is interrupted, so that the aneurysm and the malformed blood vessel in any shape can be completely blocked.
Description
Technical Field
The utility model relates to the technical field of hemangioma and angiopathy, in particular to a spring ring for photothermal treatment of hemangioma and vascular malformation.
Background
Hemangiomas and vascular malformations are the most common congenital vascular dysplasias with disease rates as high as 2%. The most common hair-growing parts comprise facial parts, four limbs, trunk parts, internal organs, brains and the like, which have adverse effects on the anatomical structure, physiological function and appearance of a human body and bring great mental stress and even psychological disorder to patients. As the lesion progresses, hemangiomas and vascular malformations can lead to complications such as rupture, ulceration, infection, heart failure, and the like. The existing treatment methods are divided into two main categories of surgical open operation and interventional therapy. Because of the advantages of small wound, fast recovery, less complications and the like, interventional therapy is the most promising treatment mode at present, including sclerosing agent injection, laser treatment, spring coil embolization and the like. For aneurysms located in terminal and branch arteries and well-defined vascular malformations of the inflow and/or outflow tract, coil embolization is the most effective treatment. The principle of spring ring embolism is to use metal embolus to mechanically occlude the lumen of the diseased artery and induce secondary thrombosis to completely close the lumen, thereby achieving the purpose of treating hemangioma and vascular malformation.
In order to accelerate the closure of the lumen of the target vessel, the current improvement mode aiming at the coil is mainly to carry out procoagulant drug coating, and the drug-coated coil mainly has the following problems: 1. the drug coating process is complex, the preparation process and the procoagulant drug cost are high, and great economic burden is brought to patients; 2. the prior art is difficult to carry out controllable release on the coating medicine; 3. under the condition that the blood vessel cavity is not completely closed, the procoagulant drug flows to a non-target lesion part along with blood, so that thrombosis is caused, and harm is caused to a patient. Therefore, the improved spring ring which is easy to prepare, controllable in curative effect and capable of targeting the diseased blood vessels has a good clinical application prospect.
SUMMERY OF THE UTILITY MODEL
The present invention aims to provide a spring coil for photothermal treatment of hemangiomas and vascular malformations that solves the problems set forth in the background above.
In order to achieve the purpose, the utility model provides the following technical scheme: the spring ring for photothermal treatment of hemangioma and vascular malformation comprises a spring ring body and a connecting mechanism, wherein the connecting mechanism is arranged outside the spring ring body;
the connecting mechanism comprises a conveying conduit, and the left end of the spring ring body penetrates through the conveying conduit and extends to the interior of the spring ring body to be contacted with the inner wall of the conveying conduit.
The spring coil body includes basic unit and light and heat nano-material coating, light and heat nano-material coating sets up the surface at the basic unit.
Preferably, the photo-thermal nano-material coating is prepared from a nano-iron compound, and the nano-iron compound is ferroferric sulfide.
Preferably, the spring coil body has a length in the range of 1cm to 50 cm.
Preferably, the cross-sectional shape of the spring coil body can be circular, semicircular, rounded rectangle and rounded triangle or a combination of different shapes.
Compared with the prior art, the utility model has the following beneficial effects:
according to the utility model, through the mutual matching of the base layer, the photo-thermal nano material coating and the conveying conduit, after the spring ring body is implanted into an aneurysm or a malformed blood vessel, the photo-thermal nano material of the surface coating can generate a heat effect under the irradiation of in-vitro near infrared light, vascular endothelial cells are damaged, local thrombosis is promoted in a controllable manner, and the blood flow in the diseased blood vessel is interrupted, so that the aneurysm and the malformed blood vessel in any shape can be completely blocked.
Drawings
FIG. 1 is a structural cross-sectional view in elevation of the present invention;
FIG. 2 is a schematic perspective view of a spring coil body according to the present invention;
FIG. 3 is a structural cross-sectional view of a right side view of the spring coil body of the present invention;
FIG. 4 is a structural cross-sectional view in elevation of one therapeutic use of the present invention;
FIG. 5 is a cross-sectional view of an alternative embodiment of the utility model in elevation during therapeutic use.
In the figure: 1 a spring coil body, 11 base layers, 12 photo-thermal nano-material coatings, 2 a connecting mechanism and 21 a conveying conduit.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example one
Referring to fig. 1-5, a spring coil for photothermal treatment of hemangioma and vascular malformation, comprising a spring coil body 1 and a connection mechanism 2, wherein the connection mechanism 2 is disposed outside the spring coil body 1, the length of the spring coil body 1 ranges from 1cm to 50cm, the cross section of the spring coil body 1 can be circular, semicircular, rectangular with rounded corners, triangular with rounded corners or a combination of different shapes, so as to adapt to hemangioma with different neck and volume and vascular malformation with different diameters.
The connecting mechanism 2 comprises a conveying conduit 21, and the left end of the spring ring body 1 penetrates through the conveying conduit 21 and extends to the inner part to be contacted with the inner wall of the conveying conduit 21.
The spring ring body 1 comprises a base layer 11 and a photo-thermal nano-material coating 12, the photo-thermal nano-material coating 12 is arranged on the surface of the base layer 11, the base layer 11 can be made of nickel, titanium, platinum, stainless steel, rhodium, rhenium and palladium or made of alloy formed by the metals, the photo-thermal nano-material coating 12 is made of a nano-iron compound, and the nano-iron compound is ferroferric sulfide.
Example two
Referring to fig. 1-5, a spring coil for photothermal treatment of hemangioma and vascular malformation, comprising a spring coil body 1 and a connection mechanism 2, wherein the connection mechanism 2 is disposed outside the spring coil body 1, the length of the spring coil body 1 ranges from 1cm to 50cm, the cross section of the spring coil body 1 can be circular, semicircular, rectangular with rounded corners, triangular with rounded corners or a combination of different shapes, so as to adapt to hemangioma with different neck and volume and vascular malformation with different diameters.
The connecting mechanism 2 comprises a conveying conduit 21, and the left end of the spring ring body 1 penetrates through the conveying conduit 21 and extends to the inner part to be contacted with the inner wall of the conveying conduit 21.
The spring ring body 1 comprises a base layer 11 and a photo-thermal nano-material coating 12, the photo-thermal nano-material coating 12 is arranged on the surface of the base layer 11, the base layer 11 can be made of nickel, titanium, platinum, stainless steel, rhodium, rhenium and palladium or made of alloy consisting of the metals, the photo-thermal nano-material coating 12 is made of a nano-copper compound, and the nano-iron compound is copper sulfide.
EXAMPLE III
Referring to fig. 1-5, a spring coil for photothermal treatment of hemangioma and vascular malformation, comprising a spring coil body 1 and a connection mechanism 2, wherein the connection mechanism 2 is disposed outside the spring coil body 1, the length of the spring coil body 1 ranges from 1cm to 50cm, the cross section of the spring coil body 1 can be circular, semicircular, rectangular with rounded corners, triangular with rounded corners or a combination of different shapes, so as to adapt to hemangioma with different neck and volume and vascular malformation with different diameters.
The connecting mechanism 2 comprises a conveying conduit 21, and the left end of the spring ring body 1 penetrates through the conveying conduit 21 and extends to the inner part to be contacted with the inner wall of the conveying conduit 21.
The spring ring body 1 comprises a base layer 11 and a photo-thermal nano-material coating 12, the photo-thermal nano-material coating 12 is arranged on the surface of the base layer 11, the base layer 11 can be made of nickel, titanium, platinum, stainless steel, rhodium, rhenium and palladium or made of alloy consisting of the metals, the photo-thermal nano-material coating 12 is made of a nano-cobalt compound, and the nano-iron compound is cobalt sulfide.
Example four
Referring to fig. 1-5, a spring coil for photothermal treatment of hemangioma and vascular malformation, comprising a spring coil body 1 and a connection mechanism 2, wherein the connection mechanism 2 is disposed outside the spring coil body 1, the length of the spring coil body 1 ranges from 1cm to 50cm, the cross section of the spring coil body 1 can be circular, semicircular, rectangular with rounded corners, triangular with rounded corners or a combination of different shapes, so as to adapt to hemangioma with different neck and volume and vascular malformation with different diameters.
The connecting mechanism 2 comprises a conveying conduit 21, and the left end of the spring ring body 1 penetrates through the conveying conduit 21 and extends to the inner part to be contacted with the inner wall of the conveying conduit 21.
The spring ring body 1 comprises a base layer 11 and a photo-thermal nano-material coating 12, the photo-thermal nano-material coating 12 is arranged on the surface of the base layer 11, the base layer 11 can be made of nickel, titanium, platinum, stainless steel, rhodium, rhenium and palladium or made of alloy consisting of the metals, the photo-thermal nano-material coating 12 is made of nano-gold, and the nano-gold is gold sulfide.
EXAMPLE five
Referring to fig. 1-5, a spring coil for photothermal treatment of hemangioma and vascular malformation, comprising a spring coil body 1 and a connection mechanism 2, wherein the connection mechanism 2 is disposed outside the spring coil body 1, the length of the spring coil body 1 ranges from 1cm to 50cm, the cross section of the spring coil body 1 can be circular, semicircular, rectangular with rounded corners, triangular with rounded corners or a combination of different shapes, so as to adapt to hemangioma with different neck and volume and vascular malformation with different diameters.
The connecting mechanism 2 comprises a conveying conduit 21, and the left end of the spring ring body 1 penetrates through the conveying conduit 21 and extends to the inner part to be contacted with the inner wall of the conveying conduit 21.
The spring ring body 1 comprises a base layer 11 and a photo-thermal nano-material coating 12, the photo-thermal nano-material coating 12 is arranged on the surface of the base layer 11, the base layer 11 can be made of nickel, titanium, platinum, stainless steel, rhodium, rhenium and palladium or an alloy formed by the metals, the photo-thermal nano-material coating 12 is made of a nano-molybdenum compound, and the nano-molybdenum compound is molybdenum oxide.
EXAMPLE six
Referring to fig. 1-5, a spring coil for photothermal treatment of hemangioma and vascular malformation, comprising a spring coil body 1 and a connection mechanism 2, wherein the connection mechanism 2 is disposed outside the spring coil body 1, the length of the spring coil body 1 ranges from 1cm to 50cm, the cross section of the spring coil body 1 can be circular, semicircular, rectangular with rounded corners, triangular with rounded corners or a combination of different shapes, so as to adapt to hemangioma with different neck and volume and vascular malformation with different diameters.
The connecting mechanism 2 comprises a conveying conduit 21, and the left end of the spring ring body 1 penetrates through the conveying conduit 21 and extends to the inner part to be contacted with the inner wall of the conveying conduit 21.
The spring ring body 1 comprises a base layer 11 and a photo-thermal nano-material coating 12, wherein the photo-thermal nano-material coating 12 is arranged on the surface of the base layer 11, the base layer 11 can be made of nickel, titanium, platinum, stainless steel, rhodium, rhenium and palladium or an alloy formed by the metals, and the photo-thermal nano-material coating 12 is made of a nano-carbon compound.
EXAMPLE seven
Referring to fig. 1-5, a spring coil for photothermal treatment of hemangioma and vascular malformation, comprising a spring coil body 1 and a connection mechanism 2, wherein the connection mechanism 2 is disposed outside the spring coil body 1, the length of the spring coil body 1 ranges from 1cm to 50cm, the cross section of the spring coil body 1 can be circular, semicircular, rectangular with rounded corners, triangular with rounded corners or a combination of different shapes, so as to adapt to hemangioma with different neck and volume and vascular malformation with different diameters.
The connecting mechanism 2 comprises a conveying conduit 21, and the left end of the spring ring body 1 penetrates through the conveying conduit 21 and extends to the inner part to be contacted with the inner wall of the conveying conduit 21.
The spring ring body 1 comprises a base layer 11 and a photo-thermal nano-material coating 12, wherein the photo-thermal nano-material coating 12 is arranged on the surface of the base layer 11, the base layer 11 can be made of nickel, titanium, platinum, stainless steel, rhodium, rhenium and palladium or an alloy formed by the metals, and the photo-thermal nano-material coating 12 is made of a nano-tungsten compound.
Experiments prove that the photothermal nano material coating 12 spring ring meets the application requirements, and the photothermal nano material coating 12 and the conveying conduit 21 are mutually matched, so that after the spring ring body 1 is implanted into an aneurysm or a malformed blood vessel, the photothermal nano material of the surface coating can generate heat effect under the irradiation of external near infrared light, vascular endothelial cells are damaged, the local thrombosis is controllably promoted, the blood flow in the diseased blood vessel is interrupted, the spring ring body 1 of the device can be completely blocked for the aneurysm and the malformed blood vessel in any shape, the clinical use number of the spring ring can be obviously reduced, the treatment cost of a patient is reduced, and great convenience is brought to the user.
The above embodiments fully prove that when the photothermal nanomaterial coating 12 spring ring of the present invention is used for embolization of hemangioma and malformed blood vessel, different spring rings of photothermal nanomaterial coating 12 can be selected according to the neck, volume, position and blood flow conditions of the diseased vessel, under the treatment of external infrared light, the complete occlusion of the diseased vessel cavity is promoted controllably, as shown in fig. 4, the delivery catheter 21 is located inside the vessel, the left side of the top of the vessel has hemangioma, as shown in fig. 5, the left side of the vessel has malformed inflow or outflow tract, the vessel is malformed, the spring ring body 1 enters the vessel through the delivery catheter 21, then reaches the diseased region and fills the hemangioma and malformed blood inflow or outflow tract, after these photothermal nanomaterial coating 12 spring rings are implanted in the hemangioma or malformed blood inflow or outflow tract, they are irradiated by near infrared light emitted by an external light source, the spring ring body 1 is implanted into hemangioma or vascular malformation for a period of time (1-2 months), the photo-thermal nano material coating 12 on the surface of the spring ring body 1 can be slowly and gradually degraded and discharged out of the body through liver and kidney circulation metabolism, fig. 4 is an aneurysm treatment process diagram, and fig. 5 is a vascular malformation treatment process diagram.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (4)
1. The utility model provides a spring coil for light and heat treatment hemangioma and vascular malformation, includes spring coil body (1) and coupling mechanism (2), its characterized in that: the connecting mechanism (2) is arranged outside the spring ring body (1);
the connecting mechanism (2) comprises a conveying guide pipe (21), and the left end of the spring ring body (1) penetrates through the conveying guide pipe (21) and extends to the inside of the spring ring body to be in contact with the inner wall of the conveying guide pipe (21);
spring coil body (1) is including basic unit (11) and light and heat nanometer material coating (12), light and heat nanometer material coating (12) set up the surface at basic unit (11).
2. A coil for photothermal treatment of hemangiomas and vascular malformations as claimed in claim 1, wherein: the photo-thermal nano material coating (12) is prepared from a nano iron compound, and the nano iron compound is ferroferric sulfide.
3. A coil for photothermal treatment of hemangiomas and vascular malformations as claimed in claim 2, wherein: the spring ring body (1) has a length ranging from 1cm to 50 cm.
4. A coil for photothermal treatment of hemangiomas and vascular malformations as claimed in claim 3, wherein: the cross section of the spring ring body (1) can be in a circular shape, a semicircular shape, a round corner rectangle, a round corner triangle or a combination of different shapes.
Priority Applications (1)
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CN202121939314.XU CN215739214U (en) | 2021-08-18 | 2021-08-18 | Spring ring for photothermal treatment of hemangioma and vascular malformation |
Applications Claiming Priority (1)
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CN202121939314.XU CN215739214U (en) | 2021-08-18 | 2021-08-18 | Spring ring for photothermal treatment of hemangioma and vascular malformation |
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CN215739214U true CN215739214U (en) | 2022-02-08 |
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CN202121939314.XU Active CN215739214U (en) | 2021-08-18 | 2021-08-18 | Spring ring for photothermal treatment of hemangioma and vascular malformation |
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2021
- 2021-08-18 CN CN202121939314.XU patent/CN215739214U/en active Active
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