CN215678341U

CN215678341U - Medicine dissolution instrument for analyzing medicine dissolution rate

Info

Publication number: CN215678341U
Application number: CN202121754922.3U
Authority: CN
Inventors: 沈载宽
Original assignee: Ponuo Tianjin Innovative Medicine Research Co ltd
Current assignee: Ponuo Tianjin Innovative Medicine Research Co ltd
Priority date: 2021-07-30
Filing date: 2021-07-30
Publication date: 2022-01-28
Anticipated expiration: 2031-07-30

Abstract

The utility model provides a drug dissolution instrument for drug dissolution analysis, and relates to the technical field of drug dissolution instruments. According to the utility model, the cleaning device is additionally arranged, the controller controls the water pump and the driving part, the recovery barrel recovers the cleaned waste liquid and the detected waste liquid, so that the detection personnel can conveniently treat the waste liquid, the driving part controls the cleaning turntable to move into the dissolution bottle to be cleaned, the water pump conveys the cleaning liquid in the cleaning barrel into the cleaning turntable, the cleaning turntable rotates and sprays the cleaning liquid, the cleaned waste liquid is pumped away through the water pumping pipe after the cleaning is finished, the dissolution bottle does not need to be manually taken down by the detection personnel for manual cleaning, the workload of the detection personnel is reduced, and meanwhile, the damage to the dissolution bottle is avoided.

Description

Medicine dissolution instrument for analyzing medicine dissolution rate

Technical Field

The utility model relates to the technical field of a drug dissolution instrument, in particular to a drug dissolution instrument for analyzing drug dissolution.

Background

The dissolution instrument is an instrument for drug dissolution experiments, and the drug dissolution instrument is a precision control system formed by a single-chip microcomputer and the like to perform centralized control on each part; the apparatus has the advantages of high automation degree, high control precision, high sensitivity, small error, low noise and convenient operation, and the drug dissolution experiment is used for evaluating the bioequivalence and bioavailability of the drug and is also an important index for evaluating the quality of the drug before clinical use.

In the prior art, for example, Chinese patent numbers are: 201821807120.2A highly effective drug dissolution instrument comprises a machine head and a machine base, wherein the machine head is fixed above the machine set through a hydraulic cylinder in a lifting way, a water bath box is arranged in the machine base, and dissolution cups are arranged in the water bath box in a matrix manner; the machine head is also provided with two-region synchronous speed regulating mechanisms, each two-region synchronous speed regulating mechanism comprises an upper supporting plate arranged in the machine head, and two synchronous speed regulating assemblies are arranged on the upper supporting plate; every synchronous speed regulation subassembly all includes six rabbling mechanisms, and every rabbling mechanism corresponds one and dissolves out the cup setting, and every rabbling mechanism all includes the fixing base, and bayonet setting (mixing) shaft on the fixing base, the top of fixing base are equipped with the synchronizing shaft, are equipped with first synchronous pulley on the synchronizing shaft. The utility model can respectively determine the rotating speed in different areas, and the rotating speed of each area can be independently set, thereby improving the working efficiency and reducing the experimental error; meanwhile, the dosing mechanism is improved, and the accuracy of the experiment is further improved.

However, after the drug dissolution instrument detects the drug dissolution instrument, the stirring cup needs to be sequentially taken out of the waste liquid in the pouring process, the stirring cup needs to be cleaned after the waste liquid is poured, the stirring cup can be carelessly broken in the cleaning process, inconvenience is brought to detection personnel, and in the cleaning process, the treatment of the waste liquid also needs to be improved. Therefore, a drug dissolution instrument for drug dissolution analysis is proposed to solve the above problems.

SUMMERY OF THE UTILITY MODEL

The utility model aims to solve the problems that in the prior art, a stirring cup needs to be cleaned manually after waste liquid is poured, the stirring cup can be broken carelessly in the cleaning process, and the waste liquid is inconvenient to treat in the cleaning process.

In order to achieve the purpose, the utility model adopts the following technical scheme: the utility model provides an appearance is dissolved out to medicine for medicine degree of dissolution analysis, includes belt cleaning device and dissolves out the appearance device, belt cleaning device's bottom and the bottom fixed connection who dissolves out the appearance device, it includes water bath, dissolves out bottle and control to dissolve out the appearance device, belt cleaning device is including wasing bucket, recycling bin and washing carousel, the one side of wasing the bucket is provided with the controller with the top of one side fixed connection what the thing recycling bin was not done to the one side of recycling bin, the top fixedly connected with water pump of controller, the top of water pump is provided with drive assembly, the one end swing joint that water pump was kept away from to drive assembly has the actuating lever, wash the carousel setting in drive assembly's bottom.

Preferably, the bottom movable mounting of actuating lever has the movable rod, the bottom of movable rod and the top fixed mounting who washs the carousel, the bottom of wasing the carousel is provided with the drinking-water pipe.

Preferably, the rear end fixedly connected with frame of water bath, the bottom fixedly connected with supporting seat of frame, the top one end of supporting seat and the bottom fixed connection who washs the bucket, it sets up the top at the water bath.

Preferably, one side of the machine base, which is far away from the cleaning device, is provided with a connecting wire, and the top of the connecting wire is provided with a switch.

Preferably, the top of one side of the base, which is far away from the cleaning device, is fixedly connected with a guide pipe, the top end of the guide pipe is fixedly connected with the rear end of the control piece, the bottom of the control piece is fixedly connected with a support column, and the bottom of the support column is fixedly connected with the top of the base.

Preferably, a plurality of stirring rods are uniformly arranged at the top end of the control piece, the number of the stirring rods is five, and an operation plate is arranged at the front end of the control piece.

Preferably, the top end of the water bath box is provided with a plurality of dissolving-out bottles, the number of the dissolving-out bottles is five, and the dissolving-out bottles are arranged at the bottom of the stirring rod.

Compared with the prior art, the utility model has the advantages and positive effects that,

1. according to the utility model, the cleaning device is additionally arranged, the controller controls the water pump and the driving part, the controller controls the water pumping pipe at the bottom of the cleaning turntable to pump the waste liquid dissolved out of the bottle into the recovery barrel, and the recovery barrel recovers the cleaned waste liquid and the detected waste liquid, so that the detection personnel can conveniently treat the waste liquid, and the problem that the waste liquid is not easy to treat after the detection is finished is solved.

2. According to the utility model, the cleaning turntable is arranged, the driving part controls the cleaning turntable to move into the dissolution bottle to be cleaned, the water pump conveys the cleaning liquid in the cleaning barrel into the cleaning turntable, the cleaning turntable starts to rotate under the control of the driving part and sprays the cleaning liquid, the outer wall of the cleaning turntable cleans the inner wall of the dissolution bottle, and the cleaned waste liquid is pumped away through the water pumping pipe after the cleaning is finished.

Drawings

FIG. 1 is a schematic perspective view of a drug dissolution apparatus for drug dissolution analysis according to the present invention;

FIG. 2 is a partial cross-sectional view of a drug dissolution apparatus for drug dissolution analysis in accordance with the present invention;

FIG. 3 is a schematic structural diagram of a cleaning apparatus of a drug dissolution apparatus for drug dissolution analysis according to the present invention;

fig. 4 is a schematic view of the bottom view of the cleaning device of the drug dissolution apparatus for drug dissolution analysis according to the present invention.

Illustration of the drawings: 1. a cleaning device; 2. a dissolution apparatus; 11. a washing barrel; 12. a recycling bin; 13. a controller; 14. a water pump; 15. a drive member; 16. a drive rod; 17. a movable rod; 18. cleaning the turntable; 19. a water pumping pipe; 21. a stirring rod; 22. a control member; 23. an operation panel; 24. a conduit; 25. a supporting seat; 26. a switch; 27. a connecting wire; 28. a water bath tank; 29. a support pillar; 30. a machine base; 31. and (4) dissolving out of the bottle.

Detailed Description

In order that the above objects, features and advantages of the present invention can be more clearly understood, the present invention will be further described with reference to the accompanying drawings and examples. It should be noted that the embodiments and features of the embodiments of the present application may be combined with each other without conflict.

In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention, however, the present invention may be practiced in other ways than those specifically described herein, and thus the present invention is not limited to the specific embodiments of the present disclosure.

Embodiment 1, as shown in fig. 1 to 4, the present invention provides a drug dissolution apparatus for drug dissolution analysis, including a cleaning device 1 and a dissolution apparatus device 2, wherein a bottom of the cleaning device 1 is fixedly connected to a bottom end of the dissolution apparatus device 2, and the dissolution apparatus device 2 includes a water bath box 28, a dissolution bottle 31 and a control member 22.

The specific arrangement and operation of the cleaning apparatus 1 and the dissolution apparatus 2 will be described below.

As shown in fig. 3 and 4, the cleaning device 1 includes a cleaning barrel 11, a recycling barrel 12 and a cleaning turntable 18, a controller 13 is arranged on one side of the cleaning barrel 11 and one side of the recycling barrel 12, a water pump 14 is fixedly connected to the top of the controller 13, a driving part 15 is arranged on the top end of the water pump 14, one end of the driving part 15, which is far away from the water pump 14, is movably connected with a driving rod 16, the cleaning turntable 18 is arranged at the bottom end of the driving part 15, a movable rod 17 is movably arranged at the bottom end of the driving rod 16, the bottom of the movable rod 17 and the top of the cleaning turntable 18 are fixedly arranged, and a water pumping pipe 19 is arranged at the bottom of the cleaning turntable 18.

The whole cleaning device 1 achieves the effects that before detection, a detector needs to add enough cleaning fluid into the cleaning barrel 11 and pour the recovery fluid in the recovery barrel 12 to ensure enough recovery space in the recovery barrel 12, after the detection of the drug dissolution instrument is finished, the stirring rod 21 is taken out from the dissolution bottle 31 at the bottom, the controller 13 controls the water pump 14 and the driving component 15 at the top through operating the controller 13, the driving component 15 controls the driving rod 16 and the movable rod 17 to move forwards and downwards into the dissolution bottle 31 to be cleaned, water pipes are respectively connected between the top ends of the cleaning barrel 11 and the recovery barrel 12 and the water pump 14, the water pump 14 conveys the cleaning fluid in the cleaning barrel 11 into the cleaning turntable 18, the controller 13 controls the water pumping pipe 19 at the bottom of the cleaning turntable 18 to pump the waste fluid in the dissolution bottle 31 into the recovery barrel 12, and then the cleaning turntable 18 starts to rotate and discharge the cleaning fluid under the control of the driving component 15, wash after the completion rethread drinking-water pipe 19 take away abluent waste liquid can, do not need the manual taking off of measurement personnel to dissolve out bottle 31 and carry out manual washing, alleviateed measurement personnel's work load, avoid causing the damage of dissolving out bottle 31 simultaneously, recovery bucket 12 retrieves abluent waste liquid and the waste liquid that detects the completion, makes things convenient for measurement personnel to handle.

As shown in fig. 1 and 2, a base 30 is fixedly connected to the rear end of a water bath tank 28, a support 25 is fixedly connected to the bottom of the base 30, one end of the top of the support 25 is fixedly connected to the bottom of a cleaning barrel 11, a cleaning turntable 18 is arranged on the top of the water bath tank 28, a connecting line 27 is arranged on one side of the base 30 away from a cleaning device 1, a switch 26 is arranged on the top of the connecting line 27, a guide tube 24 is fixedly connected to the top of one side of the base 30 away from the cleaning device 1, the top end of the guide tube 24 is fixedly connected to the rear end of a control member 22, a support column 29 is fixedly connected to the bottom of the control member 22, the bottom of the support column 29 is fixedly connected to the top of the base 30, a plurality of stirring rods 21 are uniformly arranged on the top end of the control member 22, the number of the stirring rods 21 is five, an operation panel 23 is arranged at the front end of the control member 22, a plurality of dissolution bottles 31 are arranged at the top end of the water bath tank 28, the number of the dissolution bottles 31 is five, and the dissolution bottles 31 are provided at the bottom of the stirring bar 21.

The whole dissolution instrument device 2 achieves the effects that when detection is carried out, the connecting line 27 is electrified, the medicine to be detected is placed into the corresponding dissolution bottle 31, the stirring rod 21 is controlled through the operation panel 23 to stir the liquid in the dissolution bottle 31, five dissolution bottles 31 can be simultaneously stirred and detected, and the detection efficiency is accelerated.

The above description is only a preferred embodiment of the present invention, and not intended to limit the present invention in other forms, and any person skilled in the art may apply the above modifications or changes to the equivalent embodiments with equivalent changes, without departing from the technical spirit of the present invention, and any simple modification, equivalent change and change made to the above embodiments according to the technical spirit of the present invention still belong to the protection scope of the technical spirit of the present invention.

Claims

1. A medicine dissolution instrument for analyzing medicine dissolution rate comprises a cleaning device and a dissolution instrument device, and is characterized in that: the bottom of the cleaning device is fixedly connected with the bottom end of a dissolution instrument device, and the dissolution instrument device comprises a water bath tank, a dissolution bottle and a control piece;

the cleaning device comprises a cleaning barrel, a recycling barrel and a cleaning turntable, wherein a controller is arranged at the top of the yarn recycling barrel fixedly connected to one side of the cleaning barrel and one side of the recycling barrel, a water pump is fixedly connected to the top of the controller, a driving part is arranged at the top end of the water pump, a driving rod is movably connected to one end, far away from the water pump, of the driving part, and the cleaning turntable is arranged at the bottom end of the driving part.

2. The drug dissolution apparatus for drug dissolution analysis of claim 1, wherein: the bottom movable mounting of actuating lever has the movable rod, the bottom of movable rod and the top fixed mounting who washs the carousel, the bottom of wasing the carousel is provided with the drinking-water pipe.

3. The drug dissolution apparatus for drug dissolution analysis of claim 1, wherein: the rear end fixedly connected with frame of water bath, the bottom fixedly connected with supporting seat of frame, the top one end of supporting seat and the bottom fixed connection who washs the bucket, it sets up the top at the water bath to wash the carousel.

4. The drug dissolution apparatus for drug dissolution analysis of claim 3, wherein: one side of the machine base, which is far away from the cleaning device, is provided with a connecting wire, and the top of the connecting wire is provided with a switch.

5. The drug dissolution apparatus for drug dissolution analysis of claim 3, wherein: the cleaning device is characterized in that a guide pipe is fixedly connected to the top of one side, away from the cleaning device, of the machine base, the top end of the guide pipe is fixedly connected with the rear end of the control piece, a supporting column is fixedly connected to the bottom of the control piece, and the bottom of the supporting column is fixedly connected with the top of the machine base.

6. The drug dissolution apparatus for drug dissolution analysis of claim 1, wherein: the top of control piece evenly is provided with a plurality of puddler, the quantity of puddler is five, the front end of control piece is provided with the operation panel.

7. The drug dissolution apparatus for drug dissolution analysis of claim 1, wherein: the top of water bath is provided with a plurality of and dissolves out the bottle, dissolve out the bottle quantity and be five, dissolve out the bottle and set up in the bottom of puddler.