CN215655227U - Dry and wet sample adding device for reagent - Google Patents

Dry and wet sample adding device for reagent Download PDF

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Publication number
CN215655227U
CN215655227U CN202121963714.4U CN202121963714U CN215655227U CN 215655227 U CN215655227 U CN 215655227U CN 202121963714 U CN202121963714 U CN 202121963714U CN 215655227 U CN215655227 U CN 215655227U
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China
Prior art keywords
dry
upper cover
tube
reagent
wet
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Active
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CN202121963714.4U
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Chinese (zh)
Inventor
秦月
周洪锐
魏华英
李昀地
刘钟泉
赵娜
张粲
李慧
王俊水
肖福磊
李轩
贺敬文
刘陈针玉
钱龙
李娜
孟佳
李洲
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Newscen Coast Bio Pharmaceutical Co ltd
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Newscen Coast Bio Pharmaceutical Co ltd
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Abstract

The utility model provides a sample adding device for dry and wet reagents, which comprises a tube body with openings at the upper end and the lower end, wherein the upper end and the lower end of the tube body are respectively detachably connected with an upper cover and a lower cover, a sleeve is fixed in the tube body, a solid reagent is dried in the upper cover, a liquid reagent is sealed in the sleeve, and a capillary tube for sampling is also fixed in the upper cover. Through this kind of tube-in-tube structure, realized the wet-dry separation of wet reagent futilely, make simultaneously wet-dry combine to become more simple and convenient, can directly drip appearance after reagent misce bene and detect, reduce the operating procedure, through the inside capillary of upper cover directly gather the sample, different reagent pipes can choose the capillary of different specifications for use according to the sample demand, whole reagent tube structure is reasonable, multiple functional, the cost is lower, can realize batch production.

Description

Dry and wet sample adding device for reagent
Technical Field
The utility model relates to the technical field of in-vitro diagnosis, in particular to a sample adding device for dry and wet reagents.
Background
POCT has the advantages of rapidness, sensitivity, accurate result and the like, according to the characteristics of different test methods, dry and wet reagents are sometimes required to be mixed and applied, the dry and wet reagents are required to be separated in a dry and wet manner during storage so as to avoid the dry and wet reagents from losing activity due to oxidation or other chemical reactions, and the dry and wet reagents are mixed during use, for example, a product SAA/CRP developed by the company needs to be separated in a dry and wet manner from a dry preparation and a diluent before sample adding and mixed in a dry and wet manner during sample adding, and a corresponding reagent tube capable of realizing the functions is lacked at present.
SUMMERY OF THE UTILITY MODEL
The utility model aims to overcome the defects in the prior art, and provides a sample adding device for dry and wet reagents, which can separate and store the dry and wet reagents before sample adding, can quickly mix the dry and wet reagents during sample adding, and is simple and easy to operate.
In order to achieve the purpose, the technical scheme of the utility model is that the sample adding device for the dry and wet reagents comprises a tube body with openings at the upper end and the lower end, an upper cover and a lower cover are detachably connected at the upper end of the tube body and the lower end of the tube body respectively, a sleeve is fixed in the tube body, a solid reagent is dried in the upper cover, and a liquid reagent is sealed in the sleeve.
Furthermore, a capillary tube for sampling is fixed in the upper cover.
Further, the pipe body is made of soft plastics, and an opening at the lower end of the pipe body is conical.
Adopt above-mentioned technical scheme can realize taking out the liquid reagent semi-quantitative in the body.
Further, the top of the sleeve is closed by a packaging film.
By adopting the technical scheme, the liquid reagent can be prevented from leaking before the dry and wet reagent sample adding device is used, and the sleeve can be quickly opened to quickly mix the liquid reagent and the solid reagent.
Furthermore, the capillary tube is fixed at the center of the upper cover through a support frame, the sleeve is internally tangent with the tube body, and the tube wall above the sleeve inclines towards the tube wall of the outer tube body to form a tapered tube opening.
By adopting the technical scheme, the volume of the solid reagent and the liquid reagent which flow into the sleeve after being mixed can be reduced, and the sample sucked by the capillary can be prevented from flowing into the sleeve.
Further, the upper cover and the lower cover are in threaded connection with the pipe body.
Furthermore, an interlayer is arranged at the bottom of the inner side of the lower cover, a drying agent is wrapped in the interlayer, and air in the interlayer is communicated with air in the pipe body.
By adopting the technical scheme, the solid reagent can be protected from being wetted.
Further, the upper cover and the lower cover are transparent.
By adopting the technical scheme, the dissolving condition of the solid reagent in the liquid reagent can be observed through the transparent upper cover, and the moisture condition of the sample adding device for the dry and wet reagent can be visually judged through the transparent lower cover.
Furthermore, the upper end of the sleeve extends out of the pipe body and keeps a certain distance with the top of the inner side of the upper cover.
By adopting the technical scheme, the packaged sleeve can be conveniently opened, a hand does not need to be stretched into the tube body, and the tube body is prevented from being polluted.
The sample adding device for the dry and wet reagent, which is obtained by the technical scheme, has the beneficial effects that:
the structure that the sleeve is arranged in the tube realizes the dry-wet separation before the sample adding of the dry-wet reagent, and makes the dry-wet combination more convenient in the sample adding process; a capillary tube for sampling is arranged in the upper cover at the same time, so that a sample can be directly sucked; the opening is arranged below the tube body, so that the sample can be directly dripped for detection after the reagents are uniformly mixed, the whole operation steps are reduced, the structure is reasonable, the functions are complete, the cost is low, and batch production can be realized.
Drawings
FIG. 1 is a schematic structural view of a sample adding device for dry and wet reagents according to the present invention.
FIG. 2 is an exploded view of the sample application device for dry and wet reagents according to the present invention.
Fig. 3 is a bottom view of the upper cover according to the present invention.
Fig. 4 is a top view of the tube of the present invention.
Fig. 5 is a schematic structural view of the bushing of the present invention.
In the figure, a tubular body 1; an upper cover 2; a lower cover 3; an interlayer 4; a sealing film 5; a sleeve 6; a capillary tube 7; a support frame 8.
Detailed Description
It should be noted that the embodiments and features of the embodiments may be combined with each other without conflict.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are used only for convenience in describing the present invention and for simplicity in description, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention. Furthermore, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first," "second," etc. may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless otherwise specified.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "disposed" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; the connection may be direct or indirect via an intermediate medium, and may be a communication between the two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art through specific situations.
The utility model provides a sample adding device for dry and wet reagents, which comprises a tube body 1 with openings at the upper end and the lower end, wherein the upper end of the tube body 1 and the lower end of the tube body 1 are respectively detachably connected with an upper cover 2 and a lower cover 3, a sleeve 6 is fixed in the tube body 1, a solid reagent is dried on the inner side of the upper cover 2, and a liquid reagent is sealed in the sleeve 6.
The following provides a further description of the present invention with reference to the drawings.
As shown in the figure, the sample adding device for the dry and wet reagents comprises a cylindrical tube body 1 with openings at the upper end and the lower end, wherein the tube body 1 is made of soft plastics, the opening at the lower end of the tube body 1 is conical, the upper end of the tube body 1 and the lower end of the tube body 1 are respectively in threaded connection with a transparent upper cover 2 and a transparent lower cover 3, threads are both positioned outside the tube body, the top of the inner side of the upper cover 2 is dried with a solid reagent, the bottom of the inner side of the lower cover 3 is provided with an interlayer 4, the interlayer 4 contains a drying agent, and air in the interlayer 4 is communicated with air in the tube body 1; a sleeve 6 with an opening at the upper end is fixed on the inner wall of the tube body 1, the tube wall above the sleeve 6 is inclined towards the tube wall direction of the tube body to form a conical tube opening, the upper end of the sleeve 6 extends out of the tube body 1 and keeps a certain distance with the top of the inner side of the upper cover 2, the sleeve 6 is internally tangent to the tube body 1, a liquid reagent is filled in the sleeve 6, and the opening of the sleeve 6 is sealed by a sealing film 5.
Observe the interior drier colour of lower cover 3 before the use and whether discolour to judge whether there is the possibility of weing the solid reagent of upper cover 2 inboard under the normal condition of the solid reagent in the reagent pipe, unscrew upper cover 2, tear off closing film 5, add the sample in the liquid reagent who holds in the sleeve pipe 6, screw up and invert on the desktop behind upper cover 2, wait to observe the solid reagent of upper cover 2 and the complete solution of liquid reagent after, rock the mixing, the upset the application of sample device for dry and wet reagent makes upper cover 2 up, unscrews lower cover 3, extrudes body 1, makes the mixed reagent in the body 1 extrude body 1 under the pressure effect and detect.
For convenient sample, the upper cover center still is fixed with the capillary 7 that is used for the sample, and upper cover 2 is stretched out to the lower extreme of capillary 7, its specification can be adjusted according to sample demand to capillary 7. Specifically, the capillary tube 7 is fixed at the center of the upper cover 2 through a support frame 8, one end of the support frame 8 is fixed at the top end of the inner side of the upper cover 2, the other end of the support frame 8 is fixed on the capillary tube 7, and the number of the support frames 8 is at least two; it should be noted here that, in order to avoid the capillary 7 from interfering with the sleeve 6, the diameter of the wall of the sleeve 6 is smaller than the radius of the inner wall of the tubular body 1.
Of course, the sleeve 6 may also be fixed at the central position of the tube body 1, and correspondingly, the capillary 7 is disposed at the position where the upper cover 2 is close to the inner wall of the upper cover, so long as it is ensured that the capillary 7 and the sleeve do not interfere with each other during the rotation of the upper cover 2, which should be considered to be within the protection scope of the present invention.
Example SAA/CRP reagent manufactured by this company is taken as an example, a solid reagent of 10. mu.L of a blocking agent is dried on the top of the inner side of an upper cover, a liquid reagent contained in a cannula is a diluent, and a capillary connected to the upper cover has a specification of 1.2 mm.
When the detection is carried out, whether the drying agent in the lower cover changes color or not is firstly observed to ensure that the blocking agent dry preparation is not deteriorated, the upper cover is unscrewed, the sealing film on the sleeve is torn off, 10 mu L of sample is absorbed by the capillary tube carried by the upper cover and then is added into 350 mu L of diluent in the sleeve, the upper cover is screwed down, the tube body is inverted on a table top, after the blocking agent dry preparation on the top of the inner side of the upper cover is dissolved, the upper cover is downwards and slightly swung to form two lower tube bodies, the tube bodies are shaken to enable the samples to be uniformly mixed, the tube bodies are overturned, the lower cover is unscrewed, the tube bodies are extruded, and the mixed reagent in the tube bodies is extruded under the action of pressure.
The technical solutions described above only represent the preferred technical solutions of the present invention, and some possible modifications to some parts of the technical solutions by those skilled in the art all represent the principles of the present invention, and fall within the protection scope of the present invention.

Claims (9)

1. The utility model provides a do wet application of sample device for reagent which characterized in that, includes upper and lower both ends open-ended body, and body upper end and body lower extreme can be dismantled respectively and be connected with upper cover and lower cover, and the body internal fixation has the sleeve pipe, the dry solid reagent that has in the upper cover, the encapsulation has liquid reagent in the sleeve pipe.
2. The sample adding device for dry and wet reagents according to claim 1, wherein a capillary for sampling is further fixed in the upper cover.
3. The sample adding device for dry and wet reagents according to claim 1, wherein the tube is made of soft plastic, and the lower opening of the tube is conical.
4. The sample loading device for dry and wet reagents according to claim 1, wherein the top of the sleeve is closed by a packaging film.
5. The sample adding device for dry and wet reagents according to claim 2, wherein the capillary is fixed at the center of the upper cover through a support frame, the sleeve is internally tangent to the tube body, and the tube wall above the sleeve is inclined towards the tube wall of the outer tube body to form a conical tube opening.
6. The sample adding device for dry and wet reagents according to claim 1, wherein the upper cover and the lower cover are in threaded connection with the tube body.
7. The sample adding device for the dry and wet reagents according to claim 1, wherein an interlayer is arranged at the bottom of the inner side of the lower cover, a drying agent is wrapped in the interlayer, and air in the interlayer is communicated with air in the tube body.
8. The sample loading device for dry and wet reagents according to claim 1, wherein the upper cover and the lower cover are transparent.
9. The sample adding device for dry and wet reagents according to claim 1, wherein the upper end of the sleeve extends out of the tube body and is kept at a certain distance from the top of the inner side of the upper cover.
CN202121963714.4U 2021-08-20 2021-08-20 Dry and wet sample adding device for reagent Active CN215655227U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202121963714.4U CN215655227U (en) 2021-08-20 2021-08-20 Dry and wet sample adding device for reagent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202121963714.4U CN215655227U (en) 2021-08-20 2021-08-20 Dry and wet sample adding device for reagent

Publications (1)

Publication Number Publication Date
CN215655227U true CN215655227U (en) 2022-01-28

Family

ID=79954214

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202121963714.4U Active CN215655227U (en) 2021-08-20 2021-08-20 Dry and wet sample adding device for reagent

Country Status (1)

Country Link
CN (1) CN215655227U (en)

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