CN215627960U

CN215627960U - Disposable virus sampling tube

Info

Publication number: CN215627960U
Application number: CN202123148545.1U
Authority: CN
Inventors: 郝少东; 郭敬舜; 林小靖; 曹健荣
Original assignee: Denogen Beijing Bio Sci&tech Co ltd
Current assignee: Denogen Beijing Bio Sci&tech Co ltd
Priority date: 2021-12-15
Filing date: 2021-12-15
Publication date: 2022-01-25
Anticipated expiration: 2031-12-15

Abstract

The utility model provides a disposable virus sampling tube, which comprises an upper tube body, a lower tube body and a tube cover; the upper tube body is detachably connected with the lower tube body, the upper tube body is provided with a first opening and a second opening, the lower tube body is provided with a third opening, the first opening of the upper tube body is provided with a tube cover, the second opening of the upper tube body is communicated with the third opening of the lower tube body, the inner wall of the upper tube body is provided with a separation part, a sampling swab is placed on the separation part, virus preservation liquid is stored in the lower tube body, and the virus preservation liquid can freely flow in the upper tube body and the lower tube body. The utility model has the advantages that: the structure is skillfully arranged, the swab head and the virus preservative fluid are separated in the same sampling tube space, and the production and manufacturing difficulty is low; realize the collection of virus preservative fluid to the virus through simple sampling pipe that reverses, when using automatic pipettor, only left the preservative fluid after extracting the virus after opening from the body middle part, the automation of being convenient for is moved the liquid, the automatic detection efficiency of improvement, has avoided the pollution of liquid-transfering gun.

Description

Disposable virus sampling tube

Technical Field

The utility model belongs to the technical field of biological sample collection, and particularly relates to a disposable virus sampling tube.

Background

The virus sampling tube is a commonly used disposable consumable material, and before various viruses (such as novel coronavirus, influenza a virus, influenza b virus, adenovirus, EB virus and the like) are detected, a sampled swab needs to be put into the virus sampling tube for transportation and storage.

Particularly, the new coronas are detected and sampled by a plurality of persons at present, namely a plurality of swab heads are stored in the same virus sampling tube. When liquid is taken from the virus sampling pipe, as the number of wiper heads in the same pipe is large, the amount of free flowing preservation liquid is small, a pipette tip is easy to prick the wiper head to block a tip hole, and local negative pressure is caused at the tip opening of the pipette when the liquid is sucked, so that the problem of mutual pollution is easily caused when the virus preservation liquid is flushed and sucked into the pipette barrel, and inconvenience is caused to liquid taking.

When manual liquid taking is adopted, virus preservation liquid can be manually taken from the clearance of the swab head, but when an automatic liquid moving work station such as an automatic cup separating machine and other instruments are adopted, the liquid clearance cannot be distinguished by the pipette head, and mixed liquid taking becomes a problem.

In the prior art, for a virus sampling tube for 5-10 persons to be mixed and collected, more virus preservation solution is added to solve the problem of automatic liquid taking of multi-swab mixed collection, but the virus is diluted by increasing the volume of the virus preservation solution, so that the concentration of the virus in the preservation solution is reduced, and virus detection is not facilitated. Or a plurality of special-shaped sampling tubes with tube heads and tube bodies communicated with each other are arranged, and the swab head and the virus preservation solution are respectively stored in different tube heads. However, the mode needs to pay attention to the use mode and the placement position for sampling, transportation and automatic pipetting, and is also inconvenient and not suitable for the automatic pipetting workstation to take liquid.

Disclosure of Invention

Aiming at the problems that a virus sampling tube in the prior art is inconvenient to be suitable for automatic liquid transfer operation, a liquid gun is polluted when liquid is taken, and the liquid taking efficiency is low, the utility model provides a disposable virus sampling tube, which is simple in structure manufacture and strong in practicability.

In order to achieve the purpose, the technical scheme provided by the utility model is as follows: a disposable virus sampling tube comprises an upper tube body, a lower tube body and a tube cover; the upper tube body is detachably connected with the lower tube body, the upper tube body is provided with a first opening and a second opening, the lower tube body is provided with a third opening, the first opening of the upper tube body is provided with a tube cover, the second opening of the upper tube body is communicated with the third opening of the lower tube body, the inner wall of the upper tube body is provided with a separation part, a sampling swab is placed on the separation part, virus preservation liquid is stored in the lower tube body, and the virus preservation liquid can freely flow in the upper tube body and the lower tube body.

Furthermore, the partition part is a sheet-shaped liquid-permeable fence, the liquid-permeable fence is fixedly connected with the inner wall of the upper tube body, and the clearance of the liquid-permeable fence allows virus preservation liquid to freely flow between the upper tube body and the lower tube body.

Optionally, the partition is a diaphragm made of non-woven fabric and fixedly connected to the inner wall of the upper tube, and the non-woven fabric gap allows the virus preservation solution to freely flow between the upper tube and the lower tube, so that the virus preservation solution can be roughly filtered.

Furthermore, the partition part is fixedly arranged on the inner wall of the upper pipe body through PES or TPU hot melt adhesive.

Furthermore, the first opening of the upper pipe body is provided with a first connecting part which is detachably connected with the pipe cover, the connecting part is an external thread arranged on the outer surface, and an internal thread matched with the external thread is arranged in the pipe cover.

Optionally, first connecting portion are one or more annular archs that the internal surface set up, and the tube cap is for even the lid with the integrative setting of the first opening part of last body, even is provided with circular stopper in the lid, and circular stopper can insert to first connecting portion in with annular protruding interference fit, through the plug realize the first opening part of last body be connected with dismantling of tube cap.

Furthermore, a second connecting portion is arranged at a second opening of the upper pipe body, the second connecting portion is an external thread arranged on the outer surface, a joint portion is arranged at a third opening of the lower pipe body, and the joint portion is an internal thread matched with the second connecting portion.

Optionally, the second connecting portion is one or more annular protrusions arranged on the inner surface, the engaging portion is an annular protrusion arranged on the outer wall, and the two annular protrusions are in interference fit.

Optionally, the detachable connection position of the upper pipe body and the lower pipe body is coated with sealing grease or a sealing film is wound on the outer wall.

Furthermore, the partition part is arranged at a position close to the second opening of the upper pipe body.

The utility model has the advantages that: the structure is skillfully arranged, the swab head and the virus preservation solution are separated in the same sampling tube space, and the production and manufacturing difficulty is lower. Realize the collection of virus preservative fluid to the virus through simple sampling pipe that reverses, when using automatic pipettor, open the back from the body middle part, only left the preservative fluid after extracting the virus, the automation of being convenient for is moved the liquid, and the automatic detection efficiency of improvement has avoided the pollution of liquid-moving rifle simultaneously.

Drawings

FIG. 1 is a schematic view of the overall structure of a disposable virus sampling tube;

FIG. 2 is a longitudinal half sectional view of a single use virus sampling tube;

FIG. 3 is an exploded view of a disposable virus sampling tube;

fig. 4 is a perspective sectional view of the upper tube body.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

The utility model aims at the problem that the storage of swab heads and the storage of viruses cause difficult liquid taking, and the main inventive concept is as follows: the virus sampling tube is designed into an upper section and a lower section, the upper section is used for storing the swab head, the lower section is used for storing the virus preservation solution, the upper tube body and the lower tube body are detachably connected, and the virus preservation solution can freely flow in the upper tube body and the lower tube body.

Specifically, as shown in fig. 1 and 2, the virus sampling tube includes: the pipe comprises an upper pipe body 1, a lower pipe body 2 and a pipe cover 3, wherein the upper pipe body 1 and the lower pipe body 2 are detachably connected, the upper pipe body 1 is provided with a first opening and a second opening, and the lower pipe body 2 is provided with a third opening; the tube cover 3 is provided with a first opening of the upper tube body 1, a partition part 11 is arranged in the upper tube body 1, the swab head is placed on the partition part 11 to prevent the swab from sliding into the virus preservation solution, and a second opening of the upper tube body 1 is communicated with a third opening of the lower tube body 2.

As shown in FIG. 3, the upper tube 1 is a hollow circular tube having two openings, and has a length of 47.5mm and an inner diameter of 16 mm. The first opening of the upper tube body 1 is provided with a first connecting part 12, and the first connecting part 12 is detachably connected with the tube cover 3.

First connecting portion 12 is the external screw thread that the surface set up, can mutually support with the inboard internal thread of tube cap 3, realizes going up the first opening part of body 1 and being connected dismantled of tube cap 3. Or first connecting portion 12 is the cyclic annular arch of one or more that the internal surface set up, and tube cap 3 is for covering even with the integrative lid that sets up of the first opening of body 1 down, even covers to be provided with the circular stopper that can insert to first connecting portion 12, with cyclic annular protruding interference fit, realizes going up the first opening part of body 1 and being connected dismantled of tube cap 3 through the form of plug.

The second opening of the lower pipe body 2 is provided with a second connecting part 13, the second connecting part 13 is an external thread arranged on the outer surface and can be matched with an internal thread on the inner side of the third opening of the lower pipe body 2, and the detachable connection between the first opening of the lower pipe body 1 and the lower pipe body 3 is realized. Or the second connecting part 13 is also an annular bulge arranged on the inner surface, and can be in interference fit with the inserting part at the third opening of the lower pipe body 2, and the detachable connection between the first opening of the lower pipe body 1 and the lower pipe body 3 is realized in a plugging mode.

The lower tube body 2 is a semi-closed hollow tube body with only one opening, the whole length is 47.5mm, and in order to be beneficial to the concentration of virus preservation solution in the lower tube body, the lower tube body can be set to be in a form that the inner diameter of the upper part is slightly thick and the inner diameter of the bottom part is slightly thin, and the inner diameter of the bottom part is 15.3 mm. The third opening of the lower tube body 2 is provided with a joint portion 21, and the joint portion 21 can be matched with the second connecting portion 13 of the upper tube body 1. The engagement portion 21 may take the form of an internal thread or may take the form of a spigot portion; if the form of the inserting part is adopted, an annular bulge part is arranged outside the third opening part to increase the outer diameter of the third opening part of the lower pipe body 2, and the annular bulge part is matched with the annular bulge part of the second connecting part 13 to realize the detachable connection of the lower pipe body 2 and the upper pipe body 1.

The bottom of the lower tube body 2 adopts a composite bottom in the prior art, the inner bottom is a pointed bottom protruding downwards, the outer bottom is a hollow cylindrical bottom, and the composite bottom is convenient for a liquid-transferring gun to take liquid from the tube bottom, is also favorable for centrifugation and uniform mixing and is placed in an automatic liquid-transferring machine.

The cap 3 is disposed according to the arrangement of the first connection portion 12 on the upper tube 1, and can be engaged with the upper tube 1 by using the existing internal thread or cap connection.

As shown in FIG. 4, the partition part 11 is a circular sheet-like liquid-permeable barrier having a diameter equal to the inner diameter of the upper pipe 11, and the liquid-permeable barrier is fixedly connected to the inner wall of the upper pipe 11 and is disposed near the second connecting part 13 to leave a space sufficient for storing the wiper head. The gap between the liquid-permeable fences allows the virus-retaining fluid to flow freely between the upper and lower tubular bodies while preventing the swab head from falling into the lower tubular body 2.

Or the partition part 11 is a diaphragm made of non-woven fabric, and is adhered to the inner wall of the upper pipe body 11 through hot melt adhesive such as PES (polyether sulfone), TPU (thermoplastic polyurethane) and the like, gaps of the non-woven fabric can allow the virus preservation solution to freely flow between the upper pipe body and the lower pipe body, large-particle dust or cotton swarf on the swab head can be prevented from falling into the lower pipe body 2, the coarse filtration of the virus preservation solution is realized while the contents on the swab head are extracted, and the automatic liquid transfer device is facilitated to take the solution.

The size of the whole virus sampling tube is preferably 10mL, and the amount of the virus preservation solution is about 2 mL.

In order to ensure better sealing effect of the joint between the upper pipe body 1 and the lower pipe body 2 and prevent virus preservation solution from leaking when flowing in the upper pipe body 1 and the lower pipe body 2, sealing grease can be coated at the joint position or a circle of sealing film is wound outside to be arranged, but inconvenience is not caused when the upper pipe body and the lower pipe body are disassembled.

The use mode of sampling pipe does: after the tube cover 3 is opened, the swab rod after sampling is broken off, a plurality of swab heads enter the upper tube body 1 through the first opening and are placed on the partition part 11; after sampling, the tube cap 3 is covered, then the sampling tube is inverted, so that virus preservation solution preset in the lower tube body 2 flows into the upper tube body 1, and the contents such as virus, cells, RNA and the like on the swab head are fully extracted and eluted; when the liquid needs to be taken out for detection, the sampling tube is inverted once again, so that the virus preservation liquid flows into the lower tube body 2 again through the partition part 11, the upper tube body and the lower tube body are detached and separated from the joint between the upper tube body 1 and the lower tube body 2, and the liquid is taken out from the lower tube body 2.

The above description is only for the best mode of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are included in the scope of the present invention. Those skilled in the art will appreciate that the utility model may be practiced without these specific details.

Claims

1. A disposable virus sampling tube, characterized in that: comprises an upper pipe body, a lower pipe body and a pipe cover; the upper tube body is detachably connected with the lower tube body, the upper tube body is provided with a first opening and a second opening, the lower tube body is provided with a third opening, the first opening of the upper tube body is provided with a tube cover, the second opening of the upper tube body is communicated with the third opening of the lower tube body, the inner wall of the upper tube body is provided with a separation part, a sampling swab is placed on the separation part, virus preservation liquid is stored in the lower tube body, and the virus preservation liquid can freely flow in the upper tube body and the lower tube body.

2. The single use virus sampling tube of claim 1, wherein: the partition part is a sheet-shaped liquid-permeable fence, the liquid-permeable fence is fixedly connected with the inner wall of the upper tube body, and the clearance of the liquid-permeable fence allows virus preservation liquid to freely flow between the upper tube body and the lower tube body.

3. The single use virus sampling tube of claim 1, wherein: the partition part is a diaphragm made of non-woven fabrics and is fixedly connected to the inner wall of the upper tube body, and the non-woven fabrics gap allows the virus preservation solution to freely flow between the upper tube body and the lower tube body, so that the virus preservation solution can be roughly filtered.

4. A single use virus sampling tube according to claim 3, wherein: the partition part is fixedly arranged on the inner wall of the upper pipe body through PES or TPU hot melt adhesive.

5. The single use virus sampling tube of claim 1, wherein: the first opening part of the upper pipe body is provided with a first connecting part, the connecting part is an external thread arranged on the outer surface, and an internal thread matched with the external thread is arranged in the pipe cover.

6. The single use virus sampling tube of claim 5, wherein: first connecting portion are the cyclic annular arch of one or many that the internal surface set up, and the tube cap is for covering even with the integrative lid that sets up of the first opening of last body, even is provided with circular stopper in covering, and circular stopper can insert to first connecting portion in with cyclic annular protruding interference fit, through the first opening of plug realization last body be connected with dismantling of tube cap.

7. The single use virus sampling tube of claim 1, wherein: the second opening of the upper pipe body is provided with a second connecting part, the second connecting part is an external thread arranged on the outer surface, the third opening of the lower pipe body is provided with a joint part, and the joint part is an internal thread matched with the second connecting part.

8. The single use virus sampling tube of claim 7, wherein: the second connecting part is one or more annular bulges arranged on the inner surface, the joint part is an annular bulge arranged on the outer wall, and the two parts of the annular bulges are in interference fit.

9. The single use virus sampling tube of claim 1, wherein: the detachable connection position of the upper pipe body and the lower pipe body is coated with sealing grease or the outer wall is wound with a sealing film.

10. A single use virus sampling tube according to any one of claims 1 to 9 wherein: the partition part is arranged at a position close to the second opening of the upper pipe body.