CN215611455U - Parallel reactor - Google Patents

Abstract

The utility model provides a parallel reactor which comprises a refrigerating unit, a heating unit, a stirring unit and an electric control unit, wherein the electric control unit is used for controlling the starting and the closing of the refrigerating unit, the heating unit and the stirring unit. The refrigeration unit is detachably connected to the heating unit, so that experimental operation is facilitated, and equipment is convenient to maintain and clean; the semiconductor refrigerator is arranged and matched with the cooling fan and the cooling fin to act together, so that accurate temperature control is realized; scald in the experimentation is avoided through setting up the shell in heating element periphery. The parallel reactor has the functions of high temperature control precision, small volume, large adaptive reactor capacity range and the like; can be widely used in the research work of various reactions.

Description

Parallel reactor

Technical Field

The utility model belongs to the field of reaction instruments such as chemistry and biological pharmacy, relates to a parallel reactor, and particularly relates to a stirring, heating and cooling integrated reactor with multiple test tubes for synchronous experiment and precise temperature control.

Background

The parallel heating stirrer for small-specification reaction (milligram level) is widely used in various scientific research units and research and development departments, and is almost one hand for organic chemistry laboratories. However, the existing heating stirrer mainly uses oil bath, and has the problems of being not beneficial to environmental maintenance of a laboratory, easy to overturn, easy to scald and the like; the condensing part is matched with the Schlenk tube in more ways of arranging the condensing tube in the reaction tube, and a plurality of reaction tubes need a corresponding number of return tubes, so that the experiment table is disordered, water resources are wasted, and water leakage is caused to cause water and electricity hidden troubles.

The parallel reactor is an instrument used in research, development, experiment and development, and can realize parallel synthesis reaction, thereby realizing the functions of simplifying experiment, high efficiency and accurate reaction. The parallel reaction instrument is internally provided with uniformly distributed mounting holes for mounting reaction tubes, and the reaction tubes are internally provided with medicines or chemical reactants to be reacted. The parallel test is to control the external environment to be consistent, and the research is carried out by observing the reaction condition in the reaction tube. The existing parallel reactor comprises a heating unit, a refrigerating unit, a gas circuit module and the like. The heating unit is used for heating, the refrigeration unit is used for cooling or condensing, and supporting devices such as supporting disks and supporting columns are adopted between the heating unit and the refrigeration unit.

The existing refrigeration unit comprises a cooling disc, wherein a plurality of middle holes for the reaction tubes to pass through are arranged in the cooling disc, and the middle holes are through holes with the same size. And a flow passage is arranged around the middle hole, and cold water or other liquid cold sources are introduced into the flow passage to cool the reaction tube in the middle hole. The flow channel is originally arranged as an annular groove concentric with the cooling disc, and the cooling speed of the structure is low. Patent CN107456942A discloses a parallel reactor, in which the side wall of its upper seat is provided with a flow channel, and the flow channel surrounds the adjacent cooling holes from the forward direction and the reverse direction respectively, and the curved flow channel has less cooling time and higher efficiency than the annular flow channel. However, in this way, the cooling rates of the same sides of the adjacent reaction tubes are not consistent, and in parallel experiments, the external conditions are kept consistent to ensure that the experiment results are accurate. The parallel reactor in the prior art is not provided with a temperature control system, and the reaction temperature can not be effectively controlled; without stirring, the cooling rate is slow or inconsistent. The different cooling speed and temperature can affect the result, and a scald-preventing parallel reactor which has good cooling effect and can ensure that the cooling temperature of all reaction tubes is consistent and the temperature can be accurately controlled is needed.

SUMMERY OF THE UTILITY MODEL

The utility model mainly aims to provide a parallel thermal reactor, which realizes synchronization and high efficiency of various chemical reactions, precisely controls the temperature in the chemical reaction process, prevents scalding and can observe the heating temperature and the cooling temperature in real time.

In order to achieve the above object, according to one aspect of the present invention, the present invention provides a parallel reactor, including a refrigeration unit, a heating unit, a stirring unit and an electric control unit, wherein the electric control unit is used for controlling the refrigeration unit, the heating unit and the stirring unit to be started and shut down, the parallel reactor includes a base, the stirring unit and the electric control unit are installed inside the base, the heating unit is fixedly connected to the outside of the base and above the stirring unit, and the refrigeration unit is detachably connected to the heating unit.

Furthermore, the parallel reactor also comprises a plurality of support rods, slots corresponding to each other in the upper and lower positions are respectively arranged on the refrigerating unit and the heating unit, and the support rods are detachably inserted in the slots and used for connecting the refrigerating unit and the heating unit.

Further, the heating unit includes the heating plate, the nested a plurality of reaction tanks that have in heating plate top the top of each reaction tank refrigeration unit's corresponding position is equipped with the through-hole groove for the reaction tube that holds reaction medium arranges in heat and cool off in through-hole groove and the reaction tank, the cladding of the heating unit outside has the shell.

Further, the outside of the heating unit is coated with a high-melting-point polymer shell, and the high-melting-point polymer is PPE, PPS and the like.

Further, the heating plate is made of high heat conduction material, the high heat conduction material is aviation aluminum or ceramic, and the heat conduction coefficient of the high heat conduction material is larger than 100W/mK.

Further, the refrigeration unit comprises a semiconductor refrigerator, a radiating fin and a fan, wherein the semiconductor refrigerator is arranged on the periphery of each through hole groove and is used for condensing and refluxing the reaction medium in the reaction tube; the cooling fin is arranged above the refrigerating unit and used for conducting heat generated in the reaction of the reaction tube, and the fan is arranged below the cooling fin and used for further blowing the heat on the cooling fin to the ambient environment.

Further, the stirring unit comprises a motor and rubidium iron, one end of a transmission shaft of the motor is connected with the rubidium iron, and the rubidium iron is installed below the heating plate.

Furthermore, the electronic control unit comprises an electronic control board, a control knob and a display screen, the electronic control board is installed inside the base, and the control knob and the display screen are installed on the surface of the base. The heating temperature of the heating unit, the cooling temperature of the refrigerating unit and the stirring speed of the stirring unit are displayed through the display screen.

Furthermore, the support rod is of a hollow structure, a lead groove is formed in the support rod, and the refrigeration unit is electrically connected to the electric control unit through the lead groove.

Further, the support rod is arranged to be an adjustable screw. By adopting the technical scheme, the distance between the refrigerating unit and the heating unit can be adjusted by rotating the adjusting screw rod.

Furthermore, the reaction tanks are cylindrical hollow tanks and are enclosed into a circle to form an annular structure, and the semiconductor refrigerator and the fan of the refrigeration unit are arranged above the central part of the annular structure.

The technical scheme of the utility model has the following beneficial effects:

(1) the refrigeration unit is detachably connected to the heating unit, so that experimental operation is facilitated, and equipment is convenient to maintain and clean; (2) according to the parallel reactor, the stirring module is arranged, and after the stirring module is electrified, the stirring motor rotates to drive the rubidium iron to rotate, so that the magnetons in the reaction tube rotate, and the reaction speed of a reaction medium in the reaction tube is kept balanced and stable; (3) according to the parallel reactor, the semiconductor refrigeration device is arranged, so that accurate temperature control can be realized, the cooling fan and the cooling fins are matched to act together, condensation backflow of common solvents in a laboratory is effectively realized, the cooling effect of the obtained parallel reactor is good, and the cooling temperature of all reaction tubes can be guaranteed to be consistent; (4) the heating plate of the heating unit disclosed by the utility model is made of aviation aluminum, so that high-efficiency heat transfer and heat stability can be realized, and meanwhile, the high polymer shell is arranged on the periphery of the heating plate, so that an experimenter can be prevented from being scalded in the experiment process. (5) The parallel reactor has the functions of high temperature control precision, small volume, large adaptive reactor capacity range and the like; can be widely used in the research work of various reactions.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this application, illustrate embodiments of the utility model and, together with the description, serve to explain the utility model and not to limit the utility model. In the drawings:

fig. 1 shows a schematic cross-sectional structure of the parallel reactor according to the present invention.

Fig. 2 shows a schematic exploded view of the parallel reactor according to the present invention.

Wherein the figures include the following reference numerals:

01 is a parallel reactor; 02 is a base; 10 is a heating unit; 20 is a refrigeration unit; 30 is a support rod; 50 is a stirring unit; 11 is a reaction tank; 12 is a heating plate; 13 is a heating plate shell; 21 is a semiconductor refrigerator; 22 is a heat sink; 23 is a heat radiation fan; 24 is a through hole groove (for placing a reaction tube); 25 is a reaction tube; 26 is a slot; 27 is magneton; 41 is an electric control board; 42 is a display screen; 51 is a stirring motor; 52 is rubidium iron.

Detailed Description

It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present invention will be described in detail below with reference to the embodiments with reference to the attached drawings.

It should be noted that the following detailed description is exemplary and is intended to provide further explanation of the disclosure. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs.

Spatially relative terms, such as "above … …," "above … …," "above … …," "above," and the like, may be used herein for ease of description to describe one device or feature's spatial relationship to another device or feature as illustrated in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if a device in the figures is turned over, devices described as "above" or "on" other devices or configurations would then be oriented "below" or "under" the other devices or configurations. Thus, the exemplary term "above … …" can include both an orientation of "above … …" and "below … …". The device may be otherwise variously oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.

As analyzed in the background of the present application, the parallel reactor in the prior art has a problem that a parallel heating stirrer for small-scale reaction (milligram level) is widely used in various research and development departments, and particularly, in an organic chemistry laboratory, almost one hand is needed. However, the existing heating stirrer mainly uses oil bath, and has the problems of being not beneficial to environmental maintenance of a laboratory, easy to overturn, easy to scald and the like; the condensing part is matched with the Schlenk tube in more ways of arranging the condensing tube in the reaction tube, and a plurality of reaction tubes need a corresponding number of return tubes, so that the experiment table is disordered, water resources are wasted, and water leakage is caused to cause water and electricity hidden troubles. The parallel reactor in the prior art is not provided with a temperature control system, and the reaction temperature can not be effectively controlled; without stirring, the cooling rate is slow or inconsistent. In order to solve the above problems, the present application provides a parallel reactor.

As described herein, the parallel reactor is an instrument used in research, development, and experiment, and can implement parallel synthesis reaction, thereby implementing the functions of simplifying experiment, high efficiency, and precise reaction. The parallel reaction instrument is internally provided with uniformly distributed mounting holes for mounting reaction tubes, and the reaction tubes are internally provided with medicines or chemical reactants to be reacted. The parallel test is to control the external environment to be consistent, and the research is carried out by observing the reaction condition in the reaction tube.

In order to achieve the above object, according to one aspect of the present invention, a parallel reactor is provided, which in an exemplary embodiment of the present application, comprises a refrigeration unit, a heating unit, a stirring unit and an electric control unit, wherein the electric control unit is used for controlling the refrigeration unit, the heating unit and the stirring unit to be started and shut down, the parallel reactor comprises a base, the stirring unit and the electric control unit are installed inside the base, the heating unit is fixedly connected to the outer side of the base and above the stirring unit, and the refrigeration unit is detachably connected to the heating unit.

In a specific embodiment, the parallel reactor further comprises a plurality of support rods, slots corresponding to each other in the upper and lower positions are respectively formed in the refrigeration unit and the heating unit, and the support rods are detachably inserted into the slots and used for connecting the refrigeration unit and the heating unit.

In a concrete implementation mode, the heating unit includes the heating plate, the nested a plurality of reaction tanks that have in heating plate top the top of each reaction tank refrigeration unit's corresponding position is equipped with the through-hole groove for the reaction tube that holds reaction medium arranges in heat and cool off in through-hole groove and the reaction tank, the cladding of the heating unit outside has the shell.

In some preferred embodiments, the heating unit is externally coated with a shell of a high melting polymer, such as PPE, PPS, or the like.

In one embodiment, the heating plate is made of high thermal conductivity material, and the high thermal conductivity material is aviation aluminum or ceramic, so that efficient heat transfer and thermal stability are realized.

In one embodiment, the refrigeration unit comprises a semiconductor refrigerator, a heat sink and a fan, wherein the semiconductor refrigerator is arranged at the periphery of each through hole groove and is used for condensing and refluxing the reaction medium in the reaction tube; the cooling fin is arranged above the refrigerating unit and used for conducting heat generated in the reaction of the reaction tube, and the fan is arranged below the cooling fin and used for further blowing the heat on the cooling fin to the ambient environment.

The utility model realizes the refrigeration function by utilizing the semiconductor refrigerator, the output power of the semiconductor refrigerator can be controlled by current regulation, the accurate temperature control is realized, and the controllable temperature range of the device is wide between 0 and 15 ℃. By using the Peltier effect of semiconductor materials, when direct current passes through a galvanic couple formed by serially connecting an N-type semiconductor material and a P-type semiconductor material, energy transfer can be generated after the direct current is switched on in the circuit, and the current flows from an N-type element to a joint of a P-type element to absorb heat to form a cold end; the heat is released from the joint of the P-type element flowing to the N-type element to become a hot end, and the two ends of the couple can respectively absorb the heat and release the heat, thereby achieving the purpose of refrigeration. The refrigerating technology which generates negative thermal resistance is characterized by no moving parts and higher reliability.

In a specific embodiment, the stirring unit comprises a motor and rubidium iron, one end of a transmission shaft of the motor is connected with the rubidium iron, and the rubidium iron is installed below the heating plate. Preferably, after the motor is electrified, the stirring motor rotates to drive the rubidium and iron to rotate, so as to drive the magnetons in the reaction tube to rotate, and the reaction speed of the reaction medium in the reaction tube is kept balanced and stable. In addition, because the stirring motor does not cut the motion of the magnetic induction line in the working process, the induction consumption is overcome, and the purpose of energy conservation is achieved.

In a preferred embodiment, the heating unit and the refrigerating unit further comprise a temperature measuring probe and a constant temperature controller; the refrigeration unit also comprises a heat dissipation copper pipe, a heat dissipation aluminum block and the like; the refrigeration unit or the heating unit is connected with the constant temperature controller, and the constant temperature controller corrects the temperature according to the feedback detection information of the temperature measuring probe; the temperature measuring probe is electrically connected with the electric control unit through a lead.

In a specific embodiment, the electronic control unit includes an electronic control board, a control knob and a display screen, the electronic control board is installed inside the base, and the control knob and the display screen are installed on the surface of the base. The heating temperature of the heating unit, the cooling temperature of the refrigerating unit and the stirring speed of the stirring unit are displayed through the display screen.

In one embodiment, the rotation speed of the stirring motor can be adjusted by switching the control button, specifically, the circuit is turned on and off at a fixed frequency, and the rotation speed of the stirring motor is adjusted by adjusting the frequency of the power supply. In another specific embodiment, the operation state of the motor can be adjusted by adjusting the speed by an intelligent circuit, and the rotating speed of the stirring motor can be further adjusted.

In a specific embodiment, the support rod is a hollow structure, a lead groove is arranged inside the support rod, and the refrigeration unit is electrically connected to the electronic control unit through the lead groove.

In a preferred embodiment, the support bar is provided as an adjustable screw. By adopting the technical scheme, the distance between the refrigerating unit and the heating unit can be adjusted by rotating the adjusting screw rod, so that the device is suitable for reaction tubes with different heights. The adjusting screw rod preferably selects a telescopic assembly, and the refrigerating unit is stably close to or far away from the supporting rod by adjusting the telescopic assembly. If the reaction tube highly be higher than the bracing piece and the heating unit between the interval time, the refrigeration unit that upwards slides, the refrigeration unit is kept away from the bracing piece, increases the interval between refrigeration unit and the heating unit to the height of adaptation test tube.

In one embodiment, the reaction tanks are cylindrical hollow tanks and enclose a circle to form a ring structure, and the semiconductor refrigerator and the fan of the refrigeration unit are arranged above the central part of the ring structure.

In a specific embodiment, during testing, a reaction tube is placed in a reaction tank, a reaction medium and magnetons used for stirring are contained in the reaction tube, the lower part of the reaction tube is heated by a heating unit, a solvent is condensed and refluxed by a refrigerating unit above the reaction tube, the reaction medium in the reaction tube is stirred by a stirring unit, and a stirring motor of the stirring unit rotates to drive rubidium iron to rotate so as to drive the magnetons in the reaction tube to rotate and further stir the reaction medium in the reaction tube. The display screen displays basic information such as the temperatures of the heating unit and the refrigerating unit and the stirring speed of the stirring unit. The heating unit, the refrigerating unit and the stirring unit are electrically connected with the electric control unit through conducting wires, and the heating unit, the refrigerating unit and the stirring unit are controlled to be started and closed through the electric control unit.

The advantageous effects of the present application will be described below with reference to specific examples and comparative examples.

Example 1

A parallel reactor 01, as shown in fig. 1-2, wherein the parallel reactor 01 comprises a base 02, a heating unit 10, a refrigerating unit 20, a support rod 30, an electric control unit and a stirring unit 50. The heating unit 10 is fixedly connected to the outer side of the base 02 and above the stirring unit 50, the refrigerating unit 20 is detachably connected to the heating unit 10, and the stirring unit 50 and the electric control unit are installed inside the base 02.

The heating unit 10 comprises a heating plate 12, a plurality of reaction tanks 11 are nested above the heating plate 12, through-hole grooves 24 are arranged at corresponding positions of the refrigerating unit 20 above each reaction tank 11, and reaction tubes 25 for containing reaction media are arranged in the through-hole grooves 24 and the reaction tanks 11 for heating and cooling; the diameter of the notch of the reaction tank 11 is 22mL, and the reaction tank 11 is a cylindrical hollow tank and is enclosed into a circle to form an annular structure. The heating plate 12 is made of aviation aluminum, and the heating plate shell 13 is made of PPS.

The refrigeration unit 20 is located above the heating unit 10, the refrigeration unit 20 includes a semiconductor refrigerator 21, a heat sink 22 and a heat sink fan 23, the semiconductor refrigerator 21 and the heat sink fan 23 are disposed above the central portion of the ring structure, the semiconductor refrigerator 21 is mounted on the periphery of each through hole groove 24, the semiconductor refrigerator 21 cooperates with the heat sink fan 22 and the heat sink fan 23 to act together, the heat dissipation speed is increased, condensation and backflow of common solvents in a laboratory are effectively achieved, and temperature control in the reactor 01 is achieved. The refrigeration unit 20 and the heating unit 10 are respectively provided with a slot 26 corresponding to each other in the vertical position, and the support rod 30 is detachably inserted into the slot 26 to connect the refrigeration unit 20 and the heating unit 10.

In the experiment, a reaction tube 25(25 ml Schlenk tube) was placed in the reaction tank 11, the reaction tube 25 contained a reaction medium and magnetons 27 for stirring, and the stirring unit 50 included a stirring motor 51 and rubidium iron 52. After the power is supplied, the stirring motor 51 rotates to drive the rubidium iron 52 to rotate, and further drive the magnetons 27 in the reaction tube to rotate, so as to stir the reaction medium in the reaction tube 25. The heating unit 10, the refrigerating unit 20 and the stirring unit 50 are electrically connected to an electric control unit through wires, the electric control unit comprises an electric control board 41, a display screen 42 and a control knob, the electric control board 41 is installed inside the base 02, and the control knob and the display screen 42 are installed on the surface of the base 02. The heating unit 10, the refrigerating unit 20 and the stirring unit 50 are controlled to be turned on and off by the electronic control unit. The display screen 42 is 5 inches in size, displays basic information such as the temperature of the heating unit 10 and the refrigerating unit 20 and the stirring speed of the stirring unit 50, and is arranged on one side surface of the parallel reactor 01.

Example 2

Embodiment 2 is different from embodiment 1 in that an adjusting screw is provided between the refrigerating unit and the support rod of embodiment 2.

Example 3

Example 3 differs from example 1 in that the heating disk shell of example 3 is PPE.

Comparative example 1

Comparative example 1 differs from example 1 in that the heating plate was not provided with a polymer shell on the periphery and the resulting parallel reactor was extremely vulnerable to scalding during the experiment.

Comparative example 2

Comparative example 2 differs from example 1 in that the heating disk material used a thermocouple heating disk, which is less thermally stable than the aircraft aluminum material of example 1.

Comparative example 3

Comparative example 3 differs from example 1 in that the refrigeration unit employs condensation of added condensed water. The resulting parallel reactor is extremely inconvenient to use and the reaction temperature is not controllable.

Comparative example 4

The difference between comparative example 4 and example 1 is that the refrigeration unit of comparative example 4 is fixedly connected to the heating unit, and the reaction tube of the resulting parallel reactor is not easy to handle, take and place, is not easy to maintain and clean, and is easy to scrap the whole reactor due to the failure of the refrigeration unit.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (9)

1. The utility model provides a parallel reactor, includes refrigeration unit, heating unit, stirring unit and electrical unit, electrical unit is used for control refrigeration unit, heating unit, stirring unit's start-up and closing, its characterized in that, includes the base, stirring unit and electrical unit install in inside the base, heating unit fixed connection in the base outside reaches stirring unit top, refrigeration unit detachable connect in heating unit.

2. The parallel reactor of claim 1, further comprising a plurality of support rods, wherein the cooling unit and the heating unit are respectively provided with slots corresponding to each other in the vertical direction, and the support rods are detachably inserted into the slots for connecting the cooling unit and the heating unit.

3. The parallel reactor of claim 1, wherein the heating unit comprises a heating plate, a plurality of reaction tanks are nested above the heating plate, through-hole grooves are arranged at corresponding positions of the refrigerating unit above each reaction tank, reaction tubes for containing reaction media are arranged in the through-hole grooves and the reaction tanks for heating and cooling, and the outer side of the heating unit is coated with a polymer shell.

4. The parallel reactor of claim 3, wherein the heating plate is made of a highly thermally conductive material, which is aircraft aluminum or ceramic.

5. The parallel reactor according to claim 3, wherein the refrigerating unit comprises a semiconductor refrigerator, a heat sink and a fan, the semiconductor refrigerator being installed at the periphery of each of the through-hole slots for condensing and refluxing the reaction medium in the reaction tube; the cooling fin is arranged above the refrigerating unit and used for conducting heat generated in the reaction of the reaction tube, and the fan is arranged below the cooling fin and used for further blowing the heat on the cooling fin to the ambient environment.

6. The parallel reactor of claim 3, wherein the stirring unit comprises a motor and rubidium iron, one end of a transmission shaft of the motor is connected with the rubidium iron, and the rubidium iron is arranged below the heating plate.

7. The parallel reactor of claim 3, wherein the electronic control unit comprises an electronic control board, a control knob and a display screen, the electronic control unit is installed inside the base, and the control knob and the display screen are installed on the surface of the base.

8. The parallel reactor according to claim 2, wherein the support rod is a hollow structure, a lead groove is arranged inside the support rod, and the refrigeration unit is electrically connected to the electric control unit through the lead groove.

9. The parallel reactor according to claim 5, wherein a plurality of said reaction tanks are cylindrical hollow tanks and define a ring-shaped structure, and a semiconductor refrigerator and a fan of said refrigeration unit are disposed above a central portion of said ring-shaped structure.

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