CN215609875U

CN215609875U - Dedicated high efficiency filter ultrafiltration device of liposome medicine

Info

Publication number: CN215609875U
Application number: CN202120320314.5U
Authority: CN
Inventors: 李培鹏; 朱音; 毛菊红
Original assignee: Changzhou Kinyond Pharmaceutical Manufacturing Co ltd
Current assignee: Changzhou Kinyond Pharmaceutical Manufacturing Co ltd
Priority date: 2021-02-04
Filing date: 2021-02-04
Publication date: 2022-01-25
Anticipated expiration: 2031-02-04

Abstract

The utility model discloses a special efficient filtering and ultrafiltration device for liposome medicines, relates to the technical field of liposome medicines, and aims to solve the problem that the existing special efficient filtering and ultrafiltration device for liposome medicines is complex in structure and poor in filtering effect. Sealed flange cover is all installed at high-efficient filtration ultrafiltration device's both ends, the inside of sealed flange cover one side is provided with the stoste import, the internally mounted of stoste import has the inlet pipe, the inside of high-efficient filtration ultrafiltration device opposite side is provided with the concentrate export, the inside both sides in high-efficient filtration ultrafiltration device below all are provided with the ultrafiltrate export, the externally mounted of ultrafiltrate export has the governing valve, the inside intermediate position department of high-efficient filtration ultrafiltration device installs the high-efficient outer tube that filters, the inside intermediate position department of high-efficient filtration outer tube installs honeycomb ultrafiltration device structure.

Description

Dedicated high efficiency filter ultrafiltration device of liposome medicine

Technical Field

The utility model relates to the technical field of liposome medicines, in particular to a special efficient filtering and ultrafiltration device for liposome medicines.

Background

The liposome is prepared from lecithin, ceramide, etc., has bilayer structure identical to skin cell membrane structure, and has excellent moisture keeping effect on skin, especially the liposome coated with moisture keeping substances such as hyaluronic acid, polyglucoside, etc. is more excellent moisture keeping substance; liposomes are artificial membranes; the biological definition of the drug delivery to the inside of the cell by utilizing the characteristic that the liposome can be fused with the cell membrane: when amphiphilic molecules such as phospholipids and sphingolipids are dispersed in an aqueous phase, the hydrophobic tails of the molecules tend to cluster together, avoiding the aqueous phase, while the hydrophilic heads are exposed to the aqueous phase, forming closed vesicles with a bilayer structure, called liposomes; the high-efficiency ultrafiltration device is a device which is characterized in that an asymmetric head permeable membrane made of high polymer materials by a special process flows stock solution in or out of the membrane under the action of pressure, wherein high polymer substances and colloid particles are prevented from flowing on the membrane surface and are taken away by the stock solution which flows circularly to form concentrated solution, thereby achieving the purposes of separating, concentrating and purifying the substances.

However, the existing efficient filtering ultrafiltration device special for liposome medicines has a complex structure and a poor filtering effect; therefore, the existing requirements are not met, and a special efficient filtering ultrafiltration device for liposome medicines is provided for the people.

SUMMERY OF THE UTILITY MODEL

The utility model aims to provide a special efficient filtering and ultrafiltration device for liposome medicines, and aims to solve the problem that the existing special efficient filtering and ultrafiltration device for liposome medicines in the background technology is complex in structure and poor in filtering effect.

In order to achieve the purpose, the utility model provides the following technical scheme: the utility model provides a dedicated high efficiency filter ultrafiltration device of liposome medicine, includes the high efficiency filter ultrafiltration device, sealed flange cover is all installed at the both ends of high efficiency filter ultrafiltration device, the inside of sealed flange cover one side is provided with the stoste import, the internally mounted of stoste import has the inlet pipe, the inside of high efficiency filter ultrafiltration device opposite side is provided with the concentrate export, the inside both sides in high efficiency filter ultrafiltration device below all are provided with the ultrafiltrate export, the externally mounted of ultrafiltrate export has the governing valve, the inside intermediate position department of high efficiency filter ultrafiltration device installs the high efficiency and filters the outer tube, the inside intermediate position department of high efficiency filter outer tube installs honeycomb ultrafiltration device structure.

Preferably, the high-efficiency filtering ultrafiltration device is in sealing connection with a sealing flange cover, and a sealing gasket is arranged inside the sealing flange cover.

Preferably, the inside of high efficiency filtration ultrafiltration device is provided with the ultrafiltration room, the internally mounted of ultrafiltration room has the active carbon inner bag, active carbon inner bag and ultrafiltration room fixed connection.

Preferably, the fiber ultrafiltration membrane is installed outside the honeycomb ultrafiltration device structure, the supporting block is installed outside the fiber ultrafiltration membrane, the supporting block is provided with a plurality of, and a plurality of supporting block distributes in proper order.

Preferably, an inner activated carbon filter membrane is mounted outside the supporting block, a filter element is mounted outside the inner activated carbon filter membrane, and an ultrafiltration membrane is mounted outside the filter element.

Preferably, the inside of high efficiency filter outer tube is provided with the filtration pore, the filtration pore is provided with a plurality of, and a plurality of filtration pore distributes in proper order, the internally mounted of ultrafiltrate export has the filter screen.

Compared with the prior art, the utility model has the beneficial effects that:

1. according to the utility model, the sealing flange cover, the sealing gasket, the activated carbon liner and the high-efficiency filtering outer pipe are arranged, so that the connection sealing effect is good through the connection of the sealing flange covers when the high-efficiency filtering device is used, the inside of the high-efficiency filtering outer pipe is convenient to assemble and disassemble for cleaning, the sealing performance of the joint is ensured by the sealing gasket, the activated carbon liner has the function of adsorbing toxic impurities in stock solution, the practicability is strong, the high-efficiency filtering outer pipe supports the whole filtering structure, the protection performance is strong, and the whole stability is high;

2. according to the utility model, the honeycomb ultrafiltration device structure, the fiber ultrafiltration membrane, the filter element and the inner activated carbon filter membrane are arranged, when the device is used, the honeycomb ultrafiltration device structure is used for filtering the stock solution, the outer fiber ultrafiltration membrane can effectively remove particles, colloid, bacteria, heat sources and organic matters in the stock solution, solute molecules with the size larger than the membrane pore size are intercepted into concentrated solution by the membrane, the subsequent discharge and the treatment are convenient, the filter element and the inner activated carbon filter membrane further filter the filtered stock solution, the efficient filtering effect is ensured, and the stability is high.

Drawings

FIG. 1 is a perspective view of the present invention;

FIG. 2 is a cross-sectional view of the present invention;

fig. 3 is a schematic structural diagram of the high-efficiency filtering outer pipe of the utility model.

In the figure: 1. a high-efficiency filtering ultrafiltration device; 2. sealing the flange cover; 3. a sealing gasket; 4. a stock solution inlet; 5. a feed pipe; 6. a concentrated solution outlet; 7. an ultrafiltrate outlet; 8. adjusting a valve; 9. an ultrafiltration chamber; 10. an outer tube is efficiently filtered; 11. filtering holes; 12. a filter screen; 13. an active carbon liner; 14. ultrafiltration membranes; 15. a filter element; 16. an inner activated carbon filter membrane; 17. a support block; 18. a honeycomb ultrafiltration device structure; 19. a fibrous ultrafiltration membrane.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.

Referring to fig. 1-3, an embodiment of the present invention is shown: the utility model provides a dedicated high efficiency filter ultrafiltration device of liposome medicine, including high efficiency filter ultrafiltration device 1, sealed flange cover 2 is all installed at high efficiency filter ultrafiltration device 1's both ends, the inside of 2 one sides of sealed flange cover is provided with stoste import 4, the internally mounted of stoste import 4 has inlet pipe 5, the inside of 1 opposite side of high efficiency filter ultrafiltration device is provided with concentrate export 6, the inside both sides in 1 below of high efficiency filter ultrafiltration device all are provided with ultrafiltrate export 7, the externally mounted of ultrafiltrate export 7 has governing valve 8, the operation of being convenient for, high efficiency filter ultrafiltration device 1 inside intermediate position department installs high efficiency filter outer tube 10, honeycomb ultrafiltration device structure 18 is installed to the inside intermediate position department of high efficiency filter outer tube 10, the filter effect is good.

Further, the high-efficiency filtering ultrafiltration device 1 is connected with the sealing flange cover 2 in a sealing way, and the sealing flange cover 2 is internally provided with a sealing gasket 3, so that the sealing performance is good.

Further, the inside of the high-efficiency filtering ultrafiltration device 1 is provided with an ultrafiltration chamber 9, the inside of the ultrafiltration chamber 9 is provided with an activated carbon liner 13, and the activated carbon liner 13 is fixedly connected with the ultrafiltration chamber 9 and is reliably connected.

Further, the outside of honeycomb ultrafiltration device structure 18 is installed fibre milipore filter 19, and the outside of fibre milipore filter 19 is installed supporting shoe 17, and supporting shoe 17 is provided with a plurality of, and a plurality of supporting shoe 17 distributes in proper order, and the supporting effect is good.

Furthermore, an inner activated carbon filter membrane 16 is arranged outside the supporting block 17, a filter element 15 is arranged outside the inner activated carbon filter membrane 16, and an ultrafiltration membrane 14 is arranged outside the filter element 15, so that the filtering property is strong.

Further, the inside of high efficiency filter outer tube 10 is provided with filtration pore 11, and filtration pore 11 is provided with a plurality of, and a plurality of filtration pore 11 distributes in proper order, and the internally mounted of ultrafiltrate export 7 has filter screen 12, and performance is perfect.

The working principle is as follows: when in use, the charging barrel is connected through the feeding pipe 5, the stock solution is discharged into the efficient filtering ultrafiltration device 1 through the stock solution inlet 4 through the feeding pipe 5, larger raw material substances are filtered through the honeycomb ultrafiltration device structure 18, particles, colloid, bacteria, heat sources and organic matters in the stock solution can be effectively removed through the external fiber ultrafiltration membrane 19, solute molecules with the size larger than the membrane pore diameter are intercepted into concentrated solution through a membrane, the concentrated solution is conveniently discharged through the concentrated solution outlet 6 for treatment, the supporting block 17 has high supporting stability, the filter element 15 and the internal active carbon filter membrane 16 sequentially filter particle impurities in the stock solution, the efficient filtering effect is ensured, the practicability is strong, the filtered stock solution is further filtered through the ultrafiltration membrane 14 and then discharged into the ultrafiltration chamber 9 through the filter pores 11 in the efficient filtering outer tube 10, and the active carbon inner container 13 can adsorb peculiar smell and toxic impurities in the stock solution, the protectiveness is strong, adjusts governing valve 8 at last for ultrafiltrate passes through filter screen 12 and filters the back at last and discharges through ultrafiltrate export 7, connects through sealed blind flange 2, and 3 leakproofness of seal ring are good, the loading and unloading of being convenient for.

It will be evident to those skilled in the art that the utility model is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the utility model being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Claims

1. The utility model provides a dedicated high efficiency filtration ultrafiltration device of liposome medicine, includes high efficiency filtration ultrafiltration device (1), its characterized in that: sealed flange cover (2) are all installed at the both ends of high efficiency filtration ultrafiltration device (1), the inside of sealed flange cover (2) one side is provided with stoste import (4), the internally mounted of stoste import (4) has inlet pipe (5), the inside of high efficiency filtration ultrafiltration device (1) opposite side is provided with concentrate export (6), the inside both sides in high efficiency filtration ultrafiltration device (1) below all are provided with ultrafiltrate export (7), the externally mounted of ultrafiltrate export (7) has governing valve (8), high efficiency filtration ultrafiltration device (1) inside intermediate position department installs high efficiency filtration outer tube (10), honeycomb ultrafiltration device structure (18) are installed to the inside intermediate position department of high efficiency filtration outer tube (10).

2. The high-efficiency filtering and ultra-filtering device special for the liposome medicine as claimed in claim 1, wherein: the efficient filtering ultrafiltration device (1) is in sealing connection with the sealing flange cover (2), and a sealing gasket (3) is arranged inside the sealing flange cover (2).

3. The high-efficiency filtering and ultra-filtering device special for the liposome medicine as claimed in claim 1, wherein: the inside of high efficiency filter ultrafiltration device (1) is provided with ultrafiltration room (9), the internally mounted of ultrafiltration room (9) has active carbon inner bag (13), active carbon inner bag (13) and ultrafiltration room (9) fixed connection.

4. The high-efficiency filtering and ultra-filtering device special for the liposome medicine as claimed in claim 1, wherein: the honeycomb ultrafiltration device is characterized in that a fiber ultrafiltration membrane (19) is arranged outside the honeycomb ultrafiltration device structure (18), a supporting block (17) is arranged outside the fiber ultrafiltration membrane (19), the supporting block (17) is provided with a plurality of supporting blocks (17), and the supporting blocks (17) are distributed in sequence.

5. The high-efficiency filtering and ultrafiltration device special for the liposome medicine as claimed in claim 4, wherein: the externally mounted of supporting shoe (17) has interior active carbon filter membrane (16), the externally mounted of interior active carbon filter membrane (16) has filter core (15), the externally mounted of filter core (15) has milipore filter (14).

6. The high-efficiency filtering and ultra-filtering device special for the liposome medicine as claimed in claim 1, wherein: the inside of high efficiency filter outer tube (10) is provided with filtration pore (11), filtration pore (11) are provided with a plurality of, and a plurality of filtration pore (11) distribute in proper order, the internally mounted of ultrafiltrate export (7) has filter screen (12).