CN215464499U

CN215464499U - Biological sampler of pharmacokinetics

Info

Publication number: CN215464499U
Application number: CN202121537630.4U
Authority: CN
Inventors: 姚鲁帅; 胡芝芝; 徐俊珂
Original assignee: Wuxi Zenzer Accurate Medical Laboratories Co ltd
Current assignee: Wuxi Zenzer Accurate Medical Laboratories Co ltd
Priority date: 2021-07-07
Filing date: 2021-07-07
Publication date: 2022-01-11
Anticipated expiration: 2031-07-07

Abstract

The utility model discloses a biological sampler of pharmacokinetics, belonging to the related technical field of medical equipment, the technical proposal is that the biological sampler comprises a support frame, two electric push rods push two sliding blocks to drive a support plate to move downwards, further drive the sampler and a fixed plate to move downwards until the lower end surface of the sampler enters the inside of a reagent bottle, then a motor can drive two lead screws to rotate in opposite directions, two sliding blocks drive two moving rods to move in opposite directions, further drive two clamping pieces to move, until the two clamping pieces are contacted with the outer wall of the sampler, further fix the sampler, avoid shaking in the sampling process, then manually lift or press the two pull rods upwards to contact the lower end surfaces of the two pull rods with the lower end surface of a piston, further pull the fixed plate upwards to drive the two pull rods to move upwards, and then the piston can be driven to rise in the sampler, and the effect of stable sampling of the sampler can be further completed.

Description

Biological sampler of pharmacokinetics

Technical Field

The utility model relates to the technical field related to medical equipment, in particular to a pharmacokinetic biological sampler.

Background

Pharmacokinetics, abbreviated as pharmacokinetics, is mainly used to study the dynamic changes of the body in the treatment of drugs, including the processes of absorption, distribution, biochemical conversion and excretion of drugs in the body, especially the rule of change of blood concentration with time, and the metabolism of drugs related to the age, sex, individual difference and genetic factors of people.

However, most of the existing pharmacokinetic biological samplers sample biological reagents through manual operation, but the reagent bottles and the samplers need to be held simultaneously during operation, and large pulling force needs to be applied synchronously to extract the samplers.

SUMMERY OF THE UTILITY MODEL

The utility model provides a pharmacokinetic biological sampler, and aims to solve the problem that the sampling stability of a sampler is difficult to ensure when a biological reagent is sampled.

The utility model is realized in such a way, the biological sampler of pharmacokinetics comprises two support frames, a moving groove is arranged at the opposite end of the two support frames, electric push rods are arranged on the upper end surfaces of the inner parts of the two moving grooves, sliding blocks are fixedly connected with the output ends of the two electric push rods, a support plate is arranged between the two support frames, the left side and the right side of the support plate are respectively and fixedly connected with the two sliding blocks, a through hole is arranged in the middle of the upper end surface of the support plate in a penetrating way, a sampler is arranged in the through hole, two through grooves are arranged on the lower end surface of the support plate, motors are arranged in the two through grooves, the output ends of the two motors are respectively and fixedly connected with a lead screw, the outer walls of the two lead screws are respectively and slidably connected with a sliding block, and the lower end surfaces of the two sliding blocks are respectively and fixedly connected with a moving rod, two the equal fixedly connected with holder of the relative one end of carriage release lever, two the relative one end of holder respectively with the outer wall contact of sampler, the internally mounted of sampler has the piston, the up end of piston extends to the top of sampler, the top of backup pad is provided with the fixed plate, the preceding terminal surface of fixed plate has two pull rods, two through loose axle swing joint the other end of pull rod and the lower terminal surface contact of piston, the below of backup pad is provided with places the board, place the up end middle part of board and seted up the standing groove, the standing groove is located the sampler under.

In order to realize the effect of stable sampling, the pharmacokinetic biological sampler of the utility model is preferably characterized in that the left side and the right side of the fixing plate are fixedly connected with connecting rods, the upper end surface of the supporting plate is fixedly connected with two fixing pieces, the two fixing pieces are respectively positioned on the left side and the right side of the sampler, and elastic ropes are fixedly connected between the lower end surfaces of the two connecting rods and the two fixing pieces.

In order to stably place the sampler in the through hole, the pharmacokinetic biological sampler of the utility model is preferably characterized in that the opposite ends of the two through grooves are fixedly connected with springs, the ends, close to each other, of the two springs are fixedly connected with extrusion plates, and the other ends of the two extrusion plates are abutted against the outer wall of the sampler.

In order to improve the practicability of the device, the pharmacokinetic biological sampler of the utility model is preferably characterized in that the inner wall of the placing groove is fixedly connected with an elastic ring, a reagent bottle is placed in the placing groove, and the outer wall of the reagent bottle is contacted with the elastic ring.

In order to stably hold the sampler, it is preferable that the two holding members and the two pressing plates are of an arc-shaped structure.

In order to achieve the effect of convenient and rapid sampling, the biological sampler of pharmacokinetics of the present invention is preferably configured such that the outer wall of the fixing plate is perforated with a pull groove.

In order to facilitate the movement of the device, it is preferable that the pharmacokinetic biological sampler of the present invention is provided with universal wheels on the lower end surfaces of both the two supports.

Compared with the prior art, the utility model has the beneficial effects that:

1. the pharmacokinetic biological sampler comprises a reagent bottle arranged in a placing groove, an electric push rod is started to push two sliding blocks to move downwards in a moving groove, so that the two sliding blocks drive a supporting plate to move downwards, and further drive a sampler and a fixing plate to move downwards until the lower end surface of the sampler enters the reagent bottle, two motors can be started to drive two lead screws to rotate in opposite directions, so that the two sliding blocks drive the two moving rods to move in opposite directions on the outer wall of the lead screw respectively, and further drive two clamping pieces to move in opposite directions until the two clamping pieces are in contact with the outer wall of the sampler, and further the sampler can be fixed, and the phenomenon that the sampler is shaken in the sampling process to influence the sampling effect is avoided, and the problem of manual fixing is avoided, and then the two pull rods are lifted upwards or pressed downwards manually, the lower end faces of the two pull rods are in contact with the lower end face of the piston under the action of the movable shaft, the pull groove is held by a hand, the fixed plate is pulled upwards, the fixed plate drives the two pull rods to move upwards, the piston can be driven to ascend in the sampler through the pull rods, and meanwhile the two elastic ropes can assist the fixed plate to ascend, so that the effect of stable sampling of the sampler can be achieved, the problem of manual operation is avoided, and the practicability of the device is improved;

to sum up, this kind of pharmacokinetics's biological sampler has realized that can carry out the centre gripping to the sampler stably, has guaranteed the effect of sampler at the in-process stable sample of sample, can make the pull rod drive the piston in the sampler simultaneously and rise, can be fast convenient carry out the sample operation to the practicality of device has been improved.

Drawings

FIG. 1 is a general block diagram of a pharmacokinetic biosampler of the utility model;

FIG. 2 is a cross-sectional view of a support plate of the present invention;

fig. 3 is a cross-sectional view of the standing board of the present invention.

In the figure, 1, a support frame; 101. a moving groove; 102. an electric push rod; 2. a support plate; 201. a slider; 202. a through hole; 2021. a pressing plate; 2022. a spring; 203. a through groove; 204. a motor; 205. a screw rod; 206. a slider; 207. a travel bar; 208. a clamping member; 3. a sampler; 301. a piston; 4. placing the plate; 401. a placement groove; 402. a reagent bottle; 5. a fixing plate; 501. groove drawing; 502. a pull rod; 503. a connecting rod; 504. an elastic cord; 505. a fixing member; 6. a universal wheel.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the utility model and are not intended to limit the utility model.

In the description of the present invention, it is to be understood that the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships illustrated in the drawings, and are used merely for convenience in describing the present invention and for simplicity in description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed in a particular orientation, and be operated, and thus, are not to be construed as limiting the present invention. Further, in the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.

Referring to fig. 1-3, the present invention provides a technical solution: a biological sampler of pharmacokinetics comprises two support frames 1, moving grooves 101 are respectively arranged at the opposite ends of the two support frames 1, electric push rods 102 are respectively arranged on the upper end surfaces inside the two moving grooves 101, sliding blocks 201 are respectively and fixedly connected with the output ends of the two electric push rods 102, a support plate 2 is arranged between the two support frames 1, the left side and the right side of the support plate 2 are respectively and fixedly connected with the two sliding blocks 201, a through hole 202 is arranged in the middle of the upper end surface of the support plate 2 in a penetrating way, a sampler 3 is arranged inside the through hole 202, two through grooves 203 are arranged on the lower end surface of the support plate 2, motors 204 are respectively arranged inside the two through grooves 203, lead screws 205 are respectively and fixedly connected with the output ends of the two motors 204, sliding blocks 206 are respectively and slidably connected with the outer walls of the two lead screws 205, moving rods 207 are respectively and fixedly connected with the lower end surfaces of the two sliding blocks 206, clamping pieces 208 are respectively and fixedly connected with the opposite ends of the two moving rods 207, two relative one ends of holder 208 respectively with sampler 3's outer wall contact, sampler 3's internally mounted has piston 301, the up end of piston 301 extends to sampler 3's top, the top of backup pad 2 is provided with fixed plate 5, the preceding terminal surface of fixed plate 5 has two pull rods 502 through loose axle swing joint, the other end of two pull rods 502 and piston 301's lower terminal surface contact, backup pad 2's below is provided with places board 4, place the up end middle part of board 4 and seted up standing groove 401, standing groove 401 is located sampler 3 under.

In this embodiment: the model of the motor 204 is YZR, the model of the electric push rod 102 is ANT, the reagent bottle 402 is placed in the placement groove 401, then the electric push rod 102 is started, the two electric push rods 102 push the two sliding blocks 201 to move downwards in the moving groove 101, so that the two sliding blocks 201 drive the supporting plate 2 to move downwards, and further drive the sampler 3 and the fixing plate 5 to move downwards until the lower end surface of the sampler 3 enters the inside of the reagent bottle 402, then the two motors 204 are started, so that the two motors 204 drive the two lead screws 205 to rotate in opposite directions, so that the two sliding blocks 206 drive the two moving rods 207 to move in opposite directions on the outer wall of the lead screw 205, and further drive the two clamping pieces 208 to move in opposite directions until the two clamping pieces 208 contact with the outer wall of the sampler 3, further fix the sampler 3, and avoid shaking in the sampling process and influence on the sampling effect, and avoided the manual problem of fixing of going on, lift up or push down two pull rods 502 manually immediately, make two pull rods 502 make the lower terminal surface of two pull rods 502 and the lower terminal surface contact of piston 301 under the effect of loose axle, hold kerve 501 again, upwards stimulate fixed plate 5, make fixed plate 5 drive two pull rods 502 rebound, and then accessible pull rod 502 drives piston 301 and rises in sampler 3, two stretch cord 504 can assist fixed plate 5 to rise simultaneously, and then can accomplish the effect that sampler 3 stabilizes the sample, and avoid manual operation's problem and then improved the practicality of device.

As a technical optimization scheme of the present invention, the left and right sides of the fixing plate 5 are both fixedly connected with the connecting rod 503, the upper end surface of the supporting plate 2 is fixedly connected with two fixing members 505, the two fixing members 505 are respectively located at the left and right sides of the sampler 3, and the elastic ropes 504 are both fixedly connected between the lower end surfaces of the two connecting rods 503 and the two fixing members 505.

In this embodiment: when the fixing plate 5 is pulled upwards, the fixing plate 5 can be lifted under the action of the elastic rope 504 in an auxiliary manner, the elastic rope 504 can be fixed through the fixing piece 505, and then the effect that the fixing plate 5 drives the piston 301 to stably lift is achieved, so that the effect of stable sampling is achieved.

As a technical optimization scheme of the present invention, the opposite ends of the two through slots 203 are both fixedly connected with springs 2022, the ends of the two springs 2022 close to each other are both fixedly connected with squeezing plates 2021, and the other ends of the two squeezing plates 2021 are both abutted to the outer wall of the sampler 3.

In this embodiment: the sampler 3 is manually inserted into the through hole 202, so that the outer wall of the sampler 3 extrudes the extrusion plates 2021 at the two sides, and the spring 2022 is compressed under the force until the sampler 3 completely passes through the through hole 202, and the two extrusion plates 2021 abut against the outer wall of the sampler 3, so that the sampler 3 can be stably placed in the through hole 202.

As a technical optimization scheme of the utility model, an elastic ring is fixedly connected to the inner wall of the placing groove 401, a reagent bottle 402 is placed in the placing groove 401, and the outer wall of the reagent bottle 402 is in contact with the elastic ring.

In this embodiment: reagent bottles 402 of different sizes can be placed and fixed through the elastic ring, and the practicability of the device is improved.

As a technical optimization scheme of the present invention, the two clamping members 208 and the two extrusion plates 2021 are both arc-shaped structures.

In this embodiment: by means of the two clamping members 208 and the two squeezing plates 2021, both are arc-shaped structures so as to be better matched with the sampler 3 and simultaneously stably clamp the sampler 3.

As a technical optimization scheme of the present invention, the outer wall of the fixing plate 5 is provided with a pull groove 501.

In this embodiment: through the pull groove 501, an operator can conveniently hold the pull groove 501 to pull the fixing plate 5, so that the fixing plate 5 drives the two pull rods 502 to move upwards, and further the piston 301 can be driven to move upwards, thereby realizing the effect of convenient and rapid sampling.

As a technical optimization scheme of the utility model, universal wheels 6 are arranged on the lower end surfaces of the two support frames 1.

In this embodiment: through universal wheel 6 so that place the device on the desk surface and remove, avoid inconvenient removal of taking.

The working principle is as follows: placing a reagent bottle 402 in a placing groove 401, then starting an electric push rod 102 to make the two electric push rods 102 push the two sliding blocks 201 to move downwards in a moving groove 101, making the two sliding blocks 201 drive a supporting plate 2 to move downwards, further driving a sampler 3 and a fixing plate 5 to move downwards until the lower end face of the sampler 3 enters the inside of the reagent bottle 402, then starting two motors 204 to make the two motors 204 drive two lead screws 205 to rotate in opposite directions, making the two sliding blocks 206 drive two moving rods 207 to move in opposite directions respectively on the outer wall of the lead screw 205, further driving two clamping pieces 208 to move in opposite directions until the two clamping pieces 208 are contacted with the outer wall of the sampler 3, further fixing the sampler 3, avoiding shaking in the sampling process, influencing the sampling effect and avoiding the problem of manual fixing, next, manually upwards lift or push down two pull rods 502, make two pull rods 502 make the lower terminal surface of two pull rods 502 and the lower terminal surface contact of piston 301 under the effect of loose axle, hold kerve 501 again, upwards stimulate fixed plate 5, make fixed plate 5 drive two pull rods 502 rebound, and then accessible pull rod 502 drives piston 301 and rises in sampler 3, two stretch cords 504 can assist fixed plate 5 to rise simultaneously, and then can accomplish the effect that sampler 3 stabilizes the sample, and avoid the problem of manual operation and then improved the practicality of device.

The present invention is not limited to the above preferred embodiments, and any modifications, equivalent substitutions and improvements made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A pharmacokinetic biosampler comprising two supports (1), characterized in that: the two opposite ends of the two support frames (1) are respectively provided with a moving groove (101), the upper end surfaces of the two moving grooves (101) are respectively provided with an electric push rod (102), the output ends of the two electric push rods (102) are respectively and fixedly connected with a sliding block (201), a support plate (2) is arranged between the two support frames (1), the left side and the right side of the support plate (2) are respectively and fixedly connected with the two sliding blocks (201), the middle part of the upper end surface of the support plate (2) is provided with a through hole (202) in a penetrating way, a sampler (3) is placed in the through hole (202), the lower end surface of the support plate (2) is provided with two through grooves (203), the two through grooves (203) are respectively internally provided with a motor (204), the output ends of the two motors (204) are respectively and fixedly connected with a screw rod (205), and the outer walls of the two screw rods (205) are respectively and slidably connected with a sliding block (206), the lower end surfaces of the two sliding blocks (206) are fixedly connected with moving rods (207), the opposite ends of the two moving rods (207) are fixedly connected with clamping pieces (208), the opposite ends of the two clamping pieces (208) are respectively contacted with the outer wall of the sampler (3), a piston (301) is arranged in the sampler (3), the upper end surface of the piston (301) extends to the upper part of the sampler (3), a fixed plate (5) is arranged above the supporting plate (2), the front end surface of the fixed plate (5) is movably connected with two pull rods (502) through a movable shaft, the other ends of the two pull rods (502) are contacted with the lower end surface of the piston (301), a placing plate (4) is arranged below the supporting plate (2), a placing groove (401) is formed in the middle of the upper end face of the placing plate (4), and the placing groove (401) is located under the sampler (3).

2. A pharmacokinetic biosampler according to claim 1, wherein: the equal fixedly connected with connecting rod (503) in the left and right sides of fixed plate (5), two mounting (505) of up end fixedly connected with of backup pad (2), two mounting (505) are located the left and right sides of sampler (3) respectively, two equal fixedly connected with stretch cord (504) between the lower terminal surface of connecting rod (503) and two mounting (505).

3. A pharmacokinetic biosampler according to claim 1, wherein: two equal fixedly connected with spring (2022) of the relative one end of logical groove (203), two equal fixedly connected with stripper plate (2021) of the one end that spring (2022) are close to each other, two the other end of stripper plate (2021) all with the outer wall butt of sampler (3).

4. A pharmacokinetic biosampler according to claim 1, wherein: the reagent bottle placing device is characterized in that an elastic ring is fixedly connected to the inner wall of the placing groove (401), a reagent bottle (402) is placed inside the placing groove (401), and the outer wall of the reagent bottle (402) is in contact with the elastic ring.

5. A pharmacokinetic biosampler according to claim 1, wherein: the two clamping pieces (208) and the two extrusion plates (2021) are both arc-shaped structures.

6. A pharmacokinetic biosampler according to claim 1, wherein: the outer wall of the fixing plate (5) is provided with a pull groove (501) in a penetrating way.

7. A pharmacokinetic biosampler according to claim 1, wherein: universal wheels (6) are installed on the lower end faces of the two support frames (1).