CN215462480U - Filter equipment is used in hyaluronic acid production - Google Patents

Filter equipment is used in hyaluronic acid production Download PDF

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Publication number
CN215462480U
CN215462480U CN202121302844.3U CN202121302844U CN215462480U CN 215462480 U CN215462480 U CN 215462480U CN 202121302844 U CN202121302844 U CN 202121302844U CN 215462480 U CN215462480 U CN 215462480U
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filter
pivot
box
hyaluronic acid
filtering
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CN202121302844.3U
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宫雪超
穆丹丹
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Heilongjiang Meimei Medical Technology Co ltd
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Hainan Keyimei Technology Co ltd
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Abstract

The utility model discloses a filtering device for hyaluronic acid production, and relates to the technical field of hyaluronic acid production. Including the rose box, the both sides inner wall symmetry on rose box upper portion has set firmly the backup pad, and be provided with the cartridge filter in two backup pads, the below of cartridge filter is provided with the filtration lamina membranacea, and top one side of filtering the lamina membranacea is provided with the trapped liquid export, be provided with the pivot between cartridge filter and the filtration lamina membranacea, and the bilateral symmetry of pivot is provided with a plurality of puddlers, the puddler is kept away from one side of pivot and is connected with curved scraper blade, and the scraper blade keep away from the outside protrusion of a side surface of pivot and with the bottom surface of cartridge filter, the last surface slip butt of filtration lamina membranacea, the pivot, puddler and scraper blade inside are hollow structure and communicate each other, one side of rose box sets up drive pivot pivoted motor, the opposite side of rose box is provided with the air-blower that communicates with the pivot. The utility model overcomes the defects of the prior art, accelerates the filtering speed, prevents blockage and improves the effect.

Description

Filter equipment is used in hyaluronic acid production
Technical Field
The utility model relates to the technical field of hyaluronic acid production, in particular to a filtering device for hyaluronic acid production.
Background
Hyaluronic Acid (HA) is a linear high molecular mucopolysaccharide formed from repeating units of beta-D-glucuronic acid and N-acetamidoglucose via beta, 1-3 and beta, 1-4 glycosidic bonds, the number of disaccharide units is 300-. Since the first extraction of hyaluronic acid from animal eye vitreous body by Mayer in 30 s of the present century, the research on production and application of hyaluronic acid has been over 70 years. Hyaluronic acid has unique viscoelasticity and physiological functions, is a main component of extracellular matrix, has the effects of retaining water, lubricating, regulating osmotic pressure and the like, can protect normal cells from being invaded by cytotoxicity, free radicals and the like, and can influence cell proliferation, differentiation and the like. Therefore, the hyaluronic acid is widely used in the fields of anti-adhesion after orthopedics, ophthalmology, gynecology and surgery, plastic cosmetology, health food and the like.
In order to ensure the production quality of hyaluronic acid during the production process of hyaluronic acid, a filtration operation is required. But present filter equipment filter screen is in quiescent condition basically when filtering, and the filter speed is slower, and impurity easily adheres to on the filter screen difficult clean, causes the filter screen jam, influences the filter effect. To this end, we propose a filtration device for hyaluronic acid production.
SUMMERY OF THE UTILITY MODEL
Technical problem to be solved
Aiming at the defects that in the prior art, the filtering speed is low, impurities are easy to attach to a filter screen and are not easy to clean, the filter screen is blocked, and the filtering effect is influenced, the utility model provides a filtering device for producing hyaluronic acid.
(II) technical scheme
In order to achieve the purpose, the utility model is realized by the following technical scheme:
a filtering device for hyaluronic acid production comprises a filtering box, wherein a liquid inlet is formed in the top of the filtering box, a liquid outlet is formed in the bottom of the filtering box, supporting plates are symmetrically and fixedly arranged on the inner walls of two sides of the upper portion of the filtering box, filtering cylinders are arranged on the two supporting plates, a plurality of filtering holes are uniformly formed in the surfaces of the filtering cylinders, a filtering membrane plate is arranged below the filtering cylinders, a trapped liquid outlet is formed in one side above the filtering membrane plate, a rotating shaft rotatably connected with the filtering box is arranged between the filtering cylinders and the filtering membrane plate, a plurality of stirring rods are symmetrically arranged on two sides of the rotating shaft, one side, far away from the rotating shaft, of each stirring rod is connected with an arc-shaped scraping plate, the surface, far away from the rotating shaft, of each scraping plate protrudes outwards and is in sliding butt joint with the bottom surface of the filtering cylinders and the upper surface of the filtering membrane plate, and the rotating shaft, the stirring rods and the scraping plates are all of a hollow structure and are communicated with each other, one side of rose box sets up the motor, and the output shaft top fixedly connected with initiative bevel gear of motor, the one end of pivot is passed rose box one side lateral wall and is extended to the rose box outside and fixed cover and be equipped with driven bevel gear, initiative bevel gear is connected with driven bevel gear meshing, the opposite side of rose box sets up the air-blower, the other end of pivot is passed and is linked together through the intake pipe between the output of rose box opposite side lateral wall and air-blower, and rotates through sealed bearing between intake pipe and the pivot and be connected.
According to the preferable technical scheme, the inner top wall of the filter box is fixedly connected with two annular plates, an annular groove is formed between the two annular plates, the top end of the filter cartridge is inserted into the annular groove and is connected with the inner top wall of the filter box through a first spring, and the filter cartridge is in sliding connection with the annular groove.
According to the preferable technical scheme, sliding grooves are symmetrically formed in the inner walls of the two sides of the lower portion of the filter box, the two ends of the filter membrane plate are respectively inserted into the two sliding grooves, and the lower surface of the filter membrane plate is connected with the bottom walls of the sliding grooves through second springs.
In a preferable technical scheme, a ceramic membrane with the aperture of 500nm is arranged in the middle of the filtering membrane plate.
According to the preferable technical scheme, a plurality of through holes are formed in the supporting plate in a penetrating mode.
According to the preferable technical scheme, a plurality of air outlet holes are uniformly formed in the surface of one side, far away from the rotating shaft, of the scraper.
(III) advantageous effects
The embodiment of the utility model provides a filtering device for hyaluronic acid production. The method has the following beneficial effects:
1. according to the utility model, the raw material liquid is preliminarily filtered through the filter cartridge, large-particle impurities are removed, solid-liquid separation is realized, and protein can be effectively removed and hyaluronic acid is intercepted through the arrangement of the ceramic membrane, so that the purposes of separation, concentration, purification, impurity removal, sterilization and the like are achieved.
2. According to the utility model, the motor, the driving bevel gear and the driven bevel gear are arranged to drive the rotating shaft to rotate, so that the stirring rod and the scraper are driven to rotate, the raw material liquid which is preliminarily filtered is mixed and stirred, meanwhile, in the rotating process of the scraper, one side surface of the scraper, which is far away from the rotating shaft, protrudes outwards and is in sliding butt joint with the bottom surface of the filter cartridge and the upper surface of the filter membrane plate, the filter cartridge vibrates up and down through the deformation of the first spring, the filter membrane plate vibrates up and down through the deformation of the second spring, the filtering speed is accelerated, and the filtering effect is improved.
3. According to the utility model, clean air is blown into the rotating shaft through the air blower, flows into the scraper through the stirring rod and is sprayed out through the air outlet hole, so that airflow impact is carried out on the filter cartridge and the filter membrane plate, the attachment of impurities is reduced, the blockage is avoided, the vibration effect of the filter cartridge and the filter membrane plate is further improved, and the filtering speed is accelerated.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
FIG. 1 is a schematic front sectional view of the present invention;
FIG. 2 is an enlarged view of portion A of FIG. 1;
FIG. 3 is an enlarged view of portion B of FIG. 1 according to the present invention;
FIG. 4 is a schematic view of the structure of the scraper and the air outlet of the present invention.
In the figure: the device comprises a filter box 1, a liquid inlet 2, a liquid outlet 3, a support plate 4, a filter cartridge 5, a filter hole 6, a filter membrane plate 7, a trapped liquid outlet 8, a rotating shaft 9, a stirring rod 10, a scraping plate 11, a motor 12, a driving bevel gear 13, a driven bevel gear 14, a blower 15, an air inlet pipe 16, a sealing bearing 17, an annular plate 18, an annular groove 19, a first spring 20, a chute 21, a second spring 22, a through hole 23, an air outlet hole 24 and a ceramic membrane 25.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to the attached drawings 1-4, a filtering device for hyaluronic acid production comprises a filtering box 1, wherein a liquid inlet 2 is arranged at the top of the filtering box 1, a liquid outlet 3 is arranged at the bottom of the filtering box 1, supporting plates 4 are symmetrically and fixedly arranged on the inner walls of two sides of the upper part of the filtering box 1, filter cartridges 5 are arranged on the two supporting plates 4, a plurality of filtering holes 6 are uniformly formed in the surfaces of the filter cartridges 5, a filtering membrane plate 7 is arranged below the filter cartridges 5, a liquid intercepting outlet 8 is arranged on one side above the filtering membrane plate 7, a rotating shaft 9 rotatably connected with the filtering box 1 is arranged between the filter cartridges 5 and the filtering membrane plate 7, a plurality of stirring rods 10 are symmetrically arranged on two sides of the rotating shaft 9, one side of each stirring rod 10, which is far away from the rotating shaft 9, is connected with an arc-shaped scraping plate 11, and one side surface of each scraping plate 11, which is far away from the rotating shaft 9, protrudes outwards and is connected with the bottom surface of each filtering cartridge 5, Filter the upper surface of lamina membranacea 7 and slide the butt, pivot 9, puddler 10 and scraper blade 11 are inside to be hollow structure and communicate each other, one side of rose box 1 sets up motor 12, and the output shaft top fixedly connected with drive bevel gear 13 of motor 12, the one end of pivot 9 is passed 1 lateral wall of rose box and is extended to the rose box 1 outside and fixed cover and be equipped with driven bevel gear 14, drive bevel gear 13 is connected with driven bevel gear 14 meshing, the opposite side of rose box 1 sets up air-blower 15, the other end of pivot 9 passes and is linked together through intake pipe 16 between the output of 1 opposite side lateral wall of rose box and air-blower 15, and rotates through sealed bearing 17 between intake pipe 16 and the pivot 9 and be connected. Carry out the prefilter to raw materials liquid through setting up of cartridge filter 5, get rid of large granule impurity, realize solid-liquid separation, can effectually get rid of the albumen through setting up of filtering lamina membranacea 7, hold back hyaluronic acid, through motor 12, drive pivot 9 rotations are driven in drive bevel gear 13 and driven bevel gear 14's setting, thereby drive puddler 10 and scraper blade 11 rotation, make cartridge filter 5 and filtering lamina membranacea 7 shake from top to bottom, accelerate filter speed, set up through air-blower 15 and carry out the air current impact to cartridge filter 5 and filtering lamina membranacea 7, it adheres to reduce impurity, avoid taking place the jam, further improve cartridge filter 5 and filtering lamina membranacea 7's vibrations effect simultaneously, accelerate filter speed.
In order to facilitate the up-and-down vibration of the filter cartridge 5, the inner top wall of the filter box 1 is fixedly connected with two annular plates 18, an annular groove 19 is formed between the two annular plates 18, the top end of the filter cartridge 5 is inserted into the annular groove 19 and is connected with the inner top wall of the filter box 1 through a first spring 20, and the filter cartridge 5 is slidably connected with the annular groove 19. The filter cartridge 5 is limited by the annular groove 19, so that the filter cartridge 5 is prevented from deviating, and the filter cartridge 5 slides up and down in the annular groove 19 to vibrate due to the deformation of the first spring 20.
In order to facilitate the up-and-down vibration of the filtering membrane plate 7, sliding grooves 21 are symmetrically formed in the inner walls of the two sides of the lower portion of the filtering box 1, the two ends of the filtering membrane plate 7 are respectively inserted into the two sliding grooves 21, and the lower surface of the filtering membrane plate 7 is connected with the bottom wall of the sliding grooves 21 through a second spring 22. Set up through spout 21 and carry on spacingly to filtering diaphragm 7, prevent its slippage, make cartridge filter 5 slide up and down in spout 21 and shake through the deformation of second spring 22.
In order to improve the filtering effect, a ceramic membrane 25 with a pore size of 500nm is arranged in the middle of the filtering membrane plate 7. The ceramic membrane 25 can effectively remove protein and intercept hyaluronic acid, thereby achieving the purposes of separation, concentration, purification, impurity removal, sterilization and the like.
In order to facilitate the liquid to pass through, a plurality of through holes 23 are formed in the support plate 4. The setting of backup pad 4 plays the supporting role to cartridge filter 5, is convenient for through the setting of through-hole 23 on the raw materials liquid of prefiltering falls to filtering membrane board 7 through backup pad 4.
In order to avoid blockage, a plurality of air outlet holes 24 are uniformly formed in the surface of one side of the scraper 11, which is far away from the rotating shaft 9. Set up through venthole 24 and carry out the air current to cartridge filter 5 and filter diaphragm 7 and strike, reduce impurity and adhere to, improve the filter effect.
The working principle is that when in use, raw material liquid is guided into a filter cartridge 5 of a filter box 1 from a liquid inlet 2 for preliminary filtering, a motor 12 is started to drive a driving bevel gear 13 to rotate, and further drive a driven bevel gear 14 and a rotating shaft 9 to rotate, a stirring rod 10 and a scraper 11 rotate along with the rotation, the raw material liquid after preliminary filtering is mixed and stirred, meanwhile, in the rotating process of the scraper 11, one side surface of the scraper 11, which is far away from the rotating shaft 9, protrudes outwards and is in sliding butt joint with the bottom surface of the filter cartridge 5 and the upper surface of a filter membrane plate 7, so that the filter cartridge 5 and the filter membrane plate 7 vibrate up and down, an air blower 15 is started, air flow impact is carried out on the filter cartridge 5 and the filter membrane plate 7 through an air outlet hole 24, the blockage is avoided, the vibration effect of the filter cartridge 5 and the filter membrane plate 7 is further improved, the filtering speed is accelerated, and the raw material liquid after preliminary filtering can be effectively removed of protein through a ceramic membrane 25, the waste liquid flows out from the liquid outlet 3, and the intercepted hyaluronic acid flows out from the intercepted liquid outlet 8.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.

Claims (6)

1. The utility model provides a filter equipment is used in hyaluronic acid production, includes rose box (1), the top of rose box (1) is provided with inlet (2), the bottom of rose box (1) is provided with liquid outlet (3), its characterized in that: the filter box is characterized in that supporting plates (4) are fixedly arranged on the inner walls of two sides of the upper portion of the filter box (1) symmetrically, filter cartridges (5) are arranged on the two supporting plates (4), a plurality of filter holes (6) are uniformly formed in the surfaces of the filter cartridges (5), a filter membrane plate (7) is arranged below the filter cartridges (5), a trapped liquid outlet (8) is formed in one side above the filter membrane plate (7), a rotating shaft (9) rotatably connected with the filter box (1) is arranged between the filter cartridges (5) and the filter membrane plate (7), a plurality of stirring rods (10) are symmetrically arranged on two sides of the rotating shaft (9), one side, far away from the rotating shaft (9), of each stirring rod (10) is connected with an arc-shaped scraper (11), one side surface, far away from the rotating shaft (9), of each scraper (11) protrudes outwards and is in sliding butt joint with the bottom surface of each filter cartridge (5) and the upper surface of each filter membrane plate (7), the utility model discloses a filter box, including pivot (9), puddler (10) and scraper blade (11), one side of rose box (1) sets up motor (12), and the output shaft top fixedly connected with initiative bevel gear (13) of motor (12), the one end of pivot (9) is passed filter box (1) one side lateral wall and is extended to the outside of rose box (1) and fixed cover and is equipped with driven bevel gear (14), initiative bevel gear (13) and driven bevel gear (14) meshing are connected, the opposite side of rose box (1) sets up air-blower (15), the other end of pivot (9) is passed and is linked together through intake pipe (16) between the output of filter box (1) opposite side lateral wall and air-blower (15), and rotates through sealed bearing (17) between intake pipe (16) and pivot (9) and is connected.
2. The filtration device for hyaluronic acid production according to claim 1, wherein: the utility model discloses a filter box, including rose box, filter cartridge, filter box's (1) interior roof fixedly connected with two annular plates (18), and be formed with between two annular plates (18) annular groove (19), the top of filter cartridge (5) insert in annular groove (19) and be connected through first spring (20) between the interior roof of filter box (1), filter cartridge (5) and annular groove (19) sliding connection.
3. The filtration device for hyaluronic acid production according to claim 1, wherein: sliding grooves (21) are symmetrically formed in the inner walls of the two sides of the lower portion of the filtering box (1), two ends of the filtering membrane plate (7) are inserted into the two sliding grooves (21) respectively, and the lower surface of the filtering membrane plate (7) is connected with the bottom wall of the sliding grooves (21) through a second spring (22).
4. The filtration device for hyaluronic acid production according to claim 1, wherein: the middle of the filtering membrane plate (7) is provided with a ceramic membrane (25) with the aperture of 500 nm.
5. The filtration device for hyaluronic acid production according to claim 1, wherein: a plurality of through holes (23) are arranged on the supporting plate (4) in a penetrating way.
6. The filtration device for hyaluronic acid production according to claim 1, wherein: and a plurality of air outlet holes (24) are uniformly formed in the surface of one side of the scraper (11) far away from the rotating shaft (9).
CN202121302844.3U 2021-06-11 2021-06-11 Filter equipment is used in hyaluronic acid production Active CN215462480U (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114534495A (en) * 2022-03-15 2022-05-27 湖州森诺氟材料科技有限公司 Filter membrane for medicine separation and filter device thereof
CN114748936A (en) * 2022-04-01 2022-07-15 上海格氏流体设备科技有限公司 Liquid separation filter equipment for bio-pharmaceuticals
CN114917641A (en) * 2022-05-18 2022-08-19 黄河科技学院 Solid-liquid separation equipment is used in sodium carboxymethylcellulose production
CN117225058A (en) * 2023-11-16 2023-12-15 广东康福星科技有限公司 Centrifugal intelligent self-cleaning water purifier and application method thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114534495A (en) * 2022-03-15 2022-05-27 湖州森诺氟材料科技有限公司 Filter membrane for medicine separation and filter device thereof
CN114748936A (en) * 2022-04-01 2022-07-15 上海格氏流体设备科技有限公司 Liquid separation filter equipment for bio-pharmaceuticals
CN114748936B (en) * 2022-04-01 2023-09-26 上海格氏流体设备科技有限公司 Liquid separation filter equipment for bio-pharmaceuticals
CN114917641A (en) * 2022-05-18 2022-08-19 黄河科技学院 Solid-liquid separation equipment is used in sodium carboxymethylcellulose production
CN114917641B (en) * 2022-05-18 2023-10-24 黄河科技学院 Solid-liquid separation device is used in sodium carboxymethyl cellulose production
CN117225058A (en) * 2023-11-16 2023-12-15 广东康福星科技有限公司 Centrifugal intelligent self-cleaning water purifier and application method thereof
CN117225058B (en) * 2023-11-16 2024-02-27 广东康福星科技有限公司 Centrifugal intelligent self-cleaning water purifier and application method thereof

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Address after: Room B510-2, Building 19, Innovation and Entrepreneurship Plaza, Science and Technology Innovation City, Harbin High tech Industrial Development Zone, Harbin City, Heilongjiang Province, 150023 (No. 399 Chuangxin Road)

Patentee after: Heilongjiang Meimei Medical Technology Co.,Ltd.

Country or region after: China

Address before: 570100 903-25, incubation building, Jiangdong e-commerce Industrial Park, No. 86, Qiongshan Avenue, Jiangdong new area, Haikou City, Hainan Province

Patentee before: Hainan keyimei Technology Co.,Ltd.

Country or region before: China