CN215404153U

CN215404153U - Cell harvesting adjustable bracket for cell culture bag

Info

Publication number: CN215404153U
Application number: CN202120087107.XU
Authority: CN
Inventors: 邱德辉; 谢翔峰
Original assignee: Fuzhou Carrier Biotechnology Co ltd
Current assignee: Fuzhou Carrier Biotechnology Co ltd
Priority date: 2021-01-13
Filing date: 2021-01-13
Publication date: 2022-01-04
Anticipated expiration: 2031-01-13

Abstract

The utility model provides a cell harvesting adjustable bracket for a cell culture bag, which comprises a supporting plate, a telescopic rod, a fixed rod and a base which are arranged from top to bottom in sequence, the supporting plate and two sides of the telescopic rod are obliquely provided with return springs, the upper end of the telescopic rod is hinged with the middle part below the supporting plate, the lower end of the telescopic rod is sleeved in the fixed rod, the fixed rod is provided with a plurality of clamping holes from top to bottom, the outer side of the telescopic rod is provided with a spring pin mechanism which is clamped in the clamping hole, the upper left side part of the supporting plate is provided with a slideway along the width direction of the supporting plate, a hook which can move along the slideway is arranged in the slideway, a conduit clamping block is arranged at the upper right side part of the supporting plate, a positioning groove for positioning the cell culture bag conduit is arranged in the middle of the conduit clamping block, a servo motor is arranged below the conduit clamping block, the servo motor output shaft is provided with a reel, and a pull wire is connected between the reel and the guide pipe clamping block. The utility model has reasonable design, simple structure and convenient use.

Description

Cell harvesting adjustable bracket for cell culture bag

Technical Field

The utility model relates to a cell harvesting adjustable bracket for a cell culture bag.

Background

In recent years, immunocytotherapy techniques have been rapidly developed, and have attracted attention as a means for treating tumors following surgery, radiotherapy, and chemotherapy. The immune cell treating technology includes collecting human peripheral blood, umbilical cord blood or placenta blood, separating to obtain immune cells, inducing culture in vitro to expand the immune cells greatly and enhance the target killing function, and returning the cells to patient to kill pathogen, cancer cell, mutant cell, etc. in blood and tissue. The problem of harvesting large numbers of expanded cells from culture bags before they are returned to the patient.

At the present stage, the cell harvesting mode is single, an experimenter holds the top end of the culture bag with the left hand, the right hand clamps the front part of the cell culture bag catheter 5cm away from the nozzle with hemostatic forceps, the culture bag is lifted up for pouring, and as the liquid pressure is gradually reduced, the position of holding the culture bag with the left hand is required to be continuously changed in the pouring process so as to lift the culture bag higher; therefore, great inconvenience is brought to the experimenter in the cell harvesting process; in addition, the liquid in the culture bag cannot be poured at one time, a next pouring gap needs to be waited, the catheter can be clamped by the hemostatic clamp to stand on the operating platform in the waiting process, and in the pouring process, in order to pour the liquid in the culture bag smoothly, the culture bag needs to be lifted, so that the fatigue of operators is easily caused, and the working efficiency is influenced; meanwhile, because the laboratory is in a low position, hands of a laboratory worker may pass through the upper part of the catheter port inadvertently, and the risk of pollution is caused.

SUMMERY OF THE UTILITY MODEL

The utility model improves the problems, namely the utility model aims to provide a cell harvesting adjustable bracket for a cell culture bag, which has a simple structure and is convenient to use.

The utility model is formed in such a way, which comprises a supporting plate, a telescopic rod, a fixed rod and a base which are arranged from top to bottom in sequence, the supporting plate and two sides of the telescopic rod are obliquely provided with return springs, the upper end of the telescopic rod is hinged with the middle part below the supporting plate, the lower end of the telescopic rod is sleeved in the fixed rod, the fixed rod is provided with a plurality of clamping holes from top to bottom, the outer side of the telescopic rod is provided with a spring pin mechanism which is clamped in the clamping hole, the upper left side part of the supporting plate is provided with a slideway along the width direction of the supporting plate, a hook which can move along the slideway is arranged in the slideway, a conduit clamping block is arranged at the upper right side part of the supporting plate, a positioning groove for positioning the cell culture bag conduit is arranged in the middle of the conduit clamping block, a servo motor is arranged below the conduit clamping block, the servo motor output shaft is provided with a reel, and a pull wire is connected between the reel and the guide pipe clamping block.

Further, the spring pin mechanism comprises a ball spring positioned at the side part of the telescopic rod and a ball positioned at the end part of the ball spring.

Furthermore, a storage battery is arranged in the base.

Furthermore, a sliding block in sliding fit with the sliding way is arranged below the hook.

Further, the width between two medial surfaces of constant head tank reduces from top to bottom in proper order.

Further, the guide pipe fixture block both sides are provided with the slide rail, the slide rail top is provided with the stopper, the width of stopper is greater than the slide rail, layer board right side portion is equipped with the groove of dodging that is used for dodging the guide pipe fixture block, dodge the groove both sides and be equipped with slide rail sliding fit's lift spout.

Furthermore, a buffer spring is arranged between the slide rail and the inner bottom of the lifting slide groove.

Furthermore, a pair of fixing plates is arranged below the middle of the supporting plate, the upper end of the telescopic rod is located between the two fixing plates, and a rotating pin which penetrates through the fixing plates and the telescopic rod in sequence is arranged outside the fixing plates.

Compared with the prior art, the utility model has the following beneficial effects: this device simple structure, reasonable in design can adjust the whole height of layer board through telescopic link and dead lever, moves down through the pulling pipe fixture block of acting as go-between by servo motor to the pulling layer board is to one side slope, conveniently emptys the inside liquid of cell culture bag, and the operation is swift, is favorable to the operator operation, improves work efficiency.

Drawings

FIG. 1 is a schematic structural diagram of an embodiment of the present invention;

FIG. 2 is a schematic view of a conduit block according to an embodiment of the present invention;

FIG. 3 is an enlarged view of a portion of FIG. 1 at A;

FIG. 4 is a schematic view of a spring pin mechanism according to an embodiment of the present invention;

FIG. 5 is a top view of a pallet according to an embodiment of the present invention;

FIG. 6 is a partial enlarged view of the position of the supporting plate and the fixing plate according to the embodiment of the present invention.

In the figure: 1-pallet, 110-slide, 120-avoidance groove, 130-lifting slide groove, 2-telescopic rod, 3-fixed rod, 31-clamping hole, 4-base, 5-return spring, 6-spring pin mechanism, 61-ball spring, 62-ball, 7-hook, 8-conduit clamping block, 81-positioning groove, 82-rubber layer, 9-servo motor, 10-reel, 11-pull wire, 12-storage battery, 13-slide, 14-slide rail, 15-stopper, 16-buffer spring, 17-fixed plate, 18-rotation pin.

Detailed Description

The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.

Example (b): as shown in FIGS. 1 to 6, in the present embodiment, an adjustable support for harvesting cells for a cell culture bag is provided, which comprises a support plate 1, a telescopic rod 2, a fixing rod 3 and a base 4, which are sequentially arranged from top to bottom, wherein the support plate and two sides of the telescopic rod are obliquely provided with a return spring 5, the upper end of the telescopic rod is hinged with the middle part below the support plate, the lower end of the telescopic rod is sleeved in the fixing rod, the fixing rod is provided with a plurality of clamping holes 31 from top to bottom, the outer side of the telescopic rod is provided with a spring pin mechanism 6 for clamping into the clamping holes, the upper left side part of the support plate is provided with a slide way 110 along the width direction of the support plate, a hook 7 capable of moving along the slide way is arranged in the slide way, the upper right side part of the support plate is provided with a catheter clamp block 8, the middle part of the catheter clamp block is provided with a positioning groove 81 for positioning a cell culture bag catheter, and a servo motor 9 is arranged below the catheter clamp block, the output shaft of the servo motor is provided with a reel 10, and a pull wire 11 is connected between the reel and the guide pipe clamping block.

The hook can be made of stainless steel; the slidable hook can be adapted to fixing holes designed by cell culture bags of different specifications.

The spring pin mechanism 6 comprises a ball spring 61 positioned at the side part of the telescopic rod and a ball 62 positioned at the end part of the ball spring; when the height of the supporting plate needs to be adjusted, the ball is pressed, the ball spring is compressed, and the telescopic rod is moved; when the ball is adjusted to a proper position, the ball is clamped into the clamping hole again under the action of the elastic force of the ball spring; the ball can be replaced by a pin shaft, and the end part of the pin shaft is semicircular.

In the present embodiment, a battery 12 is provided in the base.

In this embodiment, a sliding block 13 slidably engaged with the sliding way may be disposed below the hook.

In this embodiment, the width between the two inner side surfaces of the positioning groove is sequentially reduced from top to bottom; rubber layers 82 can be further arranged on two inner side surfaces of the positioning groove and used for increasing the contact friction force between the cell culture bag conduit and the positioning groove and preventing the cell culture bag conduit from falling off.

In this embodiment, the guide pipe clamping block is provided with slide rails 14 on both sides, a limiting block 15 is arranged above the slide rails, the width of the limiting block is greater than that of the slide rails, the right side portion of the supporting plate is provided with an avoiding groove 120 for avoiding the guide pipe clamping block, and the two sides of the avoiding groove are provided with lifting slide grooves 130 in sliding fit with the slide rails.

In this embodiment, a buffer spring 16 is provided between the slide rail and the inner bottom of the lifting chute for stability enhancement.

In this embodiment, in order to make layer board one side take place to empty, conveniently empty the work, layer board middle part below is equipped with a pair of fixed plate 17, and the telescopic link upper end is located between two fixed plates, and the fixed plate outside is equipped with the rotating pin 18 that runs through fixed plate and telescopic link in proper order.

In the embodiment, in operation, the cell culture bag is placed on the supporting plate, the hook is moved to a proper position of the supporting plate, the fixing hole of the cell culture bag is fixed on the hook, and the conduit of the cell culture bag is clamped in the positioning groove; the servo motor drives the reel to rotate forwards, the stay wire is utilized to move the conduit clamping block downwards along the lifting chute, the buffer spring in the conduit clamping block is extruded and contracted, when the conduit clamping block moves downwards for a certain position, the limiting block on the conduit clamping block is contacted with the surface of the supporting plate, one side of the supporting plate is driven to incline downwards, and the cell dumping work is started; when the overturning is stopped or finished, the servo motor rotates reversely, the two return springs return, the buffer spring returns, the supporting plate returns and the catheter clamping block returns; the positioning groove is higher than the supporting plate, so that the lifting of the conduit of the cell culture bag is facilitated, and the leakage is avoided; when the container is dumped again, the servo motor is restarted.

Any embodiment disclosed herein above is meant to disclose, unless otherwise indicated, all numerical ranges disclosed as being preferred, and any person skilled in the art would understand that: the preferred ranges are merely those values which are obvious or representative of the technical effect which can be achieved. Since the numerical values are too numerous to be exhaustive, some of the numerical values are disclosed in the present invention to illustrate the technical solutions of the present invention, and the above-mentioned numerical values should not be construed as limiting the scope of the present invention.

Meanwhile, if the utility model as described above discloses or relates to parts or structural members fixedly connected to each other, the fixedly connected parts can be understood as follows, unless otherwise stated: a detachable fixed connection (for example using bolts or screws) is also understood as: non-detachable fixed connections (e.g. riveting, welding), but of course, fixed connections to each other may also be replaced by one-piece structures (e.g. manufactured integrally using a casting process) (unless it is obviously impossible to use an integral forming process).

In addition, terms used in any technical solutions disclosed in the present invention to indicate positional relationships or shapes include approximate, similar or approximate states or shapes unless otherwise stated.

Any part provided by the utility model can be assembled by a plurality of independent components or can be manufactured by an integral forming process.

Finally, it should be noted that the above examples are only used to illustrate the technical solutions of the present invention and not to limit the same; although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art will understand that: modifications to the specific embodiments of the utility model or equivalent substitutions for parts of the technical features may be made; without departing from the spirit of the present invention, it is intended to cover all aspects of the utility model as defined by the appended claims.

Claims

1. A cell harvesting adjustable bracket for a cell culture bag is characterized by comprising a supporting plate, a telescopic rod, a fixed rod and a base which are arranged from top to bottom in sequence, the supporting plate and two sides of the telescopic rod are obliquely provided with return springs, the upper end of the telescopic rod is hinged with the middle part below the supporting plate, the lower end of the telescopic rod is sleeved in the fixed rod, the fixed rod is provided with a plurality of clamping holes from top to bottom, the outer side of the telescopic rod is provided with a spring pin mechanism which is clamped in the clamping hole, the upper left side part of the supporting plate is provided with a slideway along the width direction of the supporting plate, a hook which can move along the slideway is arranged in the slideway, a conduit clamping block is arranged at the upper right side part of the supporting plate, a positioning groove for positioning the cell culture bag conduit is arranged in the middle of the conduit clamping block, a servo motor is arranged below the conduit clamping block, the servo motor output shaft is provided with a reel, and a pull wire is connected between the reel and the guide pipe clamping block.

2. The adjustable cell-harvesting support for cell culture bags according to claim 1, wherein the spring-pin mechanism comprises a ball spring at the side of the telescoping rod and a ball at the end of the ball spring.

3. The adjustable cell-harvesting support for cell culture bags according to claim 1, wherein a battery is provided in the base.

4. The adjustable cell-harvesting support for cell culture bags according to claim 1, wherein a slider slidably engaged with the slide is provided under the hook.

5. The adjustable cell-harvesting support for cell culture bags according to claim 1, wherein the width between the two inner sides of the positioning groove decreases from top to bottom.

6. The adjustable cell harvesting bracket for the cell culture bag according to claim 1, wherein slide rails are arranged on two sides of the conduit clamp block, a limiting block is arranged above the slide rails, the width of the limiting block is larger than that of the slide rails, an avoiding groove for avoiding the conduit clamp block is arranged on the right side portion of the supporting plate, and lifting slide grooves which are in sliding fit with the slide rails are arranged on two sides of the avoiding groove.

7. The adjustable cell-harvesting bracket for a cell culture bag according to claim 6, wherein a buffer spring is provided between the slide rail and the inner bottom of the elevating chute.

8. The adjustable cell harvesting bracket for a cell culture bag according to claim 1, wherein a pair of fixing plates are arranged below the middle part of the supporting plate, the upper end of the telescopic rod is positioned between the two fixing plates, and a rotating pin sequentially penetrating through the fixing plates and the telescopic rod is arranged outside the fixing plates.