CN215403954U

CN215403954U - Novel purification device

Info

Publication number: CN215403954U
Application number: CN202120080889.4U
Authority: CN
Inventors: 侯杰; 王伟; 张薇; 程华
Original assignee: Nanjing Songtianshengke Biotechnology Co ltd
Current assignee: Nanjing Songtianshengke Biotechnology Co ltd
Priority date: 2021-01-13
Filing date: 2021-01-13
Publication date: 2022-01-04
Anticipated expiration: 2031-01-13

Abstract

The utility model discloses a novel purifying device, which comprises: the supporting assembly comprises two symmetrically arranged bases and supporting columns arranged on the bases; the clamping assembly comprises a positioning clamp arranged on the supporting column and a fixing clamp arranged on the positioning clamp; the bracket component comprises a liquid collecting frame clamped on the fixing clamp, connecting rods symmetrically arranged on two sides of the top of the liquid collecting frame and a gravity column bracket arranged on the top of the connecting rods, wherein a plurality of limiting holes are formed in the liquid collecting frame and the gravity column bracket respectively, and the limiting holes of the liquid collecting frame and the limiting holes of the gravity column bracket are in one-to-one correspondence; the purification assembly comprises a gravity column body and a liquid adding groove, wherein the gravity column body is arranged on a gravity column bracket and a liquid collecting frame, and the liquid adding groove is arranged at the top of the gravity column body; according to the utility model, the base comprises the base body and the embedded magnetic block at the bottom of the base body, so that the stability of the supporting component and the stability of the device are improved; the bottom of the gravity column body is conical, so that the precise drainage of liquid extraction during purification is facilitated.

Description

Novel purification device

Technical Field

The utility model relates to the technical field of protein purification, in particular to a novel purification device.

Background

The separation and purification of proteins is widely used in biochemical research applications and is an important operation technology. A typical eukaryotic cell may contain thousands of different proteins, some very abundant, some containing only a few copies. To study a protein, the protein must first be purified from other proteins and non-protein molecules. Generally, the laboratory purified protein is based on the principle of high cost performance, and a simple and labor-saving gravity column is preferred. The partner of the gravity column is generally a test tube clamp, the test tube clamp can only clamp one column, and a large amount of proteins cannot be purified due to low experimental efficiency, so that a novel purification device is provided.

SUMMERY OF THE UTILITY MODEL

The utility model aims to provide a novel purification device, which solves the problems in the background technology.

In order to achieve the purpose, the utility model provides the following technical scheme: a novel purification device comprising:

the supporting assembly comprises two symmetrically arranged bases and supporting columns arranged on the bases;

the clamping assembly comprises a positioning clamp arranged on the supporting column and a fixing clamp arranged on the positioning clamp;

the bracket component comprises a liquid collecting frame clamped on the fixing clamp, connecting rods symmetrically arranged on two sides of the top of the liquid collecting frame and a gravity column bracket arranged on the top of the connecting rods, wherein a plurality of limiting holes are formed in the liquid collecting frame and the gravity column bracket respectively, and the limiting holes of the liquid collecting frame and the limiting holes of the gravity column bracket are in one-to-one correspondence;

the purification component comprises a gravity column body arranged on a gravity column bracket and a liquid collecting frame and a liquid adding groove arranged at the top of the gravity column body.

Preferably, the base comprises a base body and a magnetic block embedded at the bottom of the base body.

Preferably, the positioning fixture comprises a fixing block fixedly mounted on the support column, a height positioning hole formed in the rear side of the fixing block, a horizontal positioning hole formed in the front side of the fixing block, and fixing bolts symmetrically screwed on the front side and the rear side of the fixing block.

Preferably, the support column is provided with scale marks.

Preferably, the supporting column is inserted into the height positioning hole, and the fixing block is inserted into the horizontal positioning hole.

Preferably, the bottom of the gravity column body is tapered.

Compared with the prior art, the utility model has the following beneficial effects: the arrangement of the base comprising the base body and the embedded magnetic block at the bottom of the base body is beneficial to increasing the stability of the supporting component and further increasing the stability of the device; the arrangement of the scale marks on the supporting columns is favorable for accurately adjusting the height of the positioning clamp, so that the effect of maintaining the support assembly and the purification assembly to be horizontal is achieved; the supporting columns are inserted into the height positioning holes, and the fixing blocks are inserted into the horizontal positioning holes, so that the fixing and position adjusting of the clamping assembly are facilitated; the bottom of the gravity column body is conical, so that the precise drainage of liquid extraction during purification is facilitated.

Drawings

Other features, objects and advantages of the utility model will become more apparent upon reading of the detailed description of non-limiting embodiments with reference to the following drawings:

FIG. 1 is an installation view of the present invention;

FIG. 2 is a block diagram of the clamping assembly of the present invention;

fig. 3 is a view showing the construction of the bracket assembly of the present invention.

In the figure: 100. the device comprises a supporting component, 110, a base, 111, a base body, 112, a magnetic block, 120, a supporting column, 200, a clamping component, 210, a positioning clamp, 211, a fixing block, 212, a height positioning hole, 213, a horizontal positioning hole, 214, a fixing bolt, 220, a fixing clamp, 300, a bracket component, 310, a liquid receiving frame, 320, a connecting rod, 330, a gravity column bracket, 400, a purifying component, 410, a gravity column body, 420 and a liquid adding groove.

Detailed Description

In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the utility model easy to understand, the utility model is further described with the specific embodiments.

The utility model provides a novel purification device which can simultaneously purify multiple groups and greatly increase the test efficiency.

Fig. 1 to 3 are schematic structural views illustrating an embodiment of a novel purification apparatus according to the present invention, and referring to fig. 1 to 3, a main body of the novel purification apparatus includes a support assembly 100, a holding assembly 200, a support assembly 300, and a purification assembly 400.

The supporting assembly 100 is used for supporting the clamping assembly 200, the bracket assembly 300 and the purifying assembly 400, specifically, the supporting assembly 100 comprises two bases 110 symmetrically arranged and supporting columns 120 installed on the bases 110, when in use, the bases 110 with larger mass and diameter support the supporting columns 120, so as to keep the stability of the supporting columns 120, further maintain the stability of the clamping assembly 200 installed on the supporting columns 120, and ensure the stable work of the bracket assembly 300 and the purifying assembly 400;

the clamping assembly 200 is used for fixing the bracket assembly 300 and adjusting the height of the bracket assembly 300, specifically, the clamping assembly 200 comprises a positioning clamp 210 mounted on the supporting column 120 and a fixing clamp 220 mounted on the positioning clamp 210, when in use, the fixing clamp 220 of the clamping assembly 200 is fixed with the supporting frame, then the fixing clamp 220 is fixed on the positioning clamp 210, then the positioning clamp 210 is fixed on the supporting column 120, and when the position needs to be adjusted, only the height of the positioning clamp 210 on the supporting column 120 needs to be adjusted;

the bracket assembly 300 is used for realizing simultaneous work of multiple groups of purification assemblies 400 to increase purification efficiency, specifically, the bracket assembly 300 comprises a liquid collecting frame 310 clamped on the fixing clamp 220, connecting rods 320 symmetrically installed on two sides of the top of the liquid collecting frame 310 and a gravity column bracket 330 installed on the top of the connecting rods 320, multiple limiting holes are formed in the liquid collecting frame 310 and the gravity column bracket 330, the limiting holes of the liquid collecting frame 310 and the gravity column bracket 330 are in one-to-one correspondence, and when the purification assembly is used, the multiple groups of purification assemblies 400 are sequentially inserted into the limiting holes of the liquid collecting frame 310 from the limiting holes in the gravity column bracket 330;

the purification assembly 400 is used for purifying protein, and specifically, the purification assembly 400 comprises a gravity column body 410 arranged on the gravity column support 330 and the liquid collecting frame 310 and a liquid adding groove 420 arranged at the top of the gravity column body 410, when in use, a stock solution to be purified is added into the liquid adding groove 420, and under the influence of gravity, the stock solution enters the gravity column body 410 and is purified under the influence of gravity.

The base 110 includes a base body 111 and a magnetic block 112 embedded at the bottom of the base body 111, which is beneficial to increasing the stability of the supporting assembly 100 and further increasing the stability of the device; the positioning fixture 210 comprises a fixed block 211 fixedly arranged on the support column 120, a height positioning hole 212 arranged at the rear side of the fixed block 211, a horizontal positioning hole 213 arranged at the front side of the fixed block 211, and fixing bolts 214 symmetrically screwed on the front side and the rear side of the fixed block 211; the support column 120 is provided with scale marks, which is beneficial to accurately adjusting the height of the positioning fixture 210, so as to maintain the support assembly 300 and the purification assembly 400 to be horizontal; the supporting column 120 is inserted into the height positioning hole 212, and the fixing block 211 is inserted into the horizontal positioning hole 213, so that the fixing and position adjustment of the clamping assembly 200 are facilitated; the bottom of the gravity column body 410 is conical, which is beneficial to the precise drainage of the purified liquid.

The working principle is as follows: when the novel purifying device is used, the supporting component 100 is firstly placed on a metal test bed or a metal test table, the supporting component 100 is fixed under the influence of magnetic force, then the positioning clamp 210 is installed on the supporting component 100 and adjusted to a proper height, then the bracket component 300 is clamped and fixed on the positioning clamp 210, then the purifying component 400 is installed on the bracket component 300, then the collecting container is placed at the lower part of the purifying component 400, and the purifying component 400 is used for purifying.

While there have been shown and described what are at present considered the fundamental principles and essential features of the utility model and its advantages, it will be apparent to those skilled in the art that the utility model is not limited to the details of the foregoing exemplary embodiments, but is capable of other specific forms without departing from the spirit or essential characteristics thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the utility model being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims

1. A novel purification device, comprising:

the supporting assembly (100) comprises two symmetrically arranged bases (110) and supporting columns (120) arranged on the bases (110);

the clamping assembly (200) comprises a positioning clamp (210) arranged on the supporting column (120) and a fixing clamp (220) arranged on the positioning clamp (210);

the bracket component (300) comprises a liquid collecting frame (310) clamped on the fixing clamp (220), connecting rods (320) symmetrically installed on two sides of the top of the liquid collecting frame (310) and a gravity column bracket (330) installed on the top of the connecting rods (320), a plurality of limiting holes are formed in the liquid collecting frame (310) and the gravity column bracket (330), and the limiting holes of the liquid collecting frame (310) and the gravity column bracket (330) are in one-to-one correspondence;

the purification assembly (400) comprises a gravity column body (410) arranged on the gravity column bracket (330) and the liquid collecting frame (310) and a liquid adding groove (420) arranged at the top of the gravity column body (410).

2. The new purification device as claimed in claim 1, wherein the base (110) comprises a base body (111) and a magnetic block (112) embedded in the bottom of the base body (111).

3. The novel purification device as claimed in claim 1, wherein the positioning fixture (210) comprises a fixing block (211) fixedly mounted on the supporting column (120), a height positioning hole (212) formed at the rear side of the fixing block (211), a horizontal positioning hole (213) formed at the front side of the fixing block (211), and fixing bolts (214) symmetrically screwed at the front side and the rear side of the fixing block (211).

4. The new purification device as claimed in claim 1, wherein the support column (120) is provided with graduation marks.

5. A novel purification device as claimed in claim 3, wherein the support column (120) is inserted into the height positioning hole (212) and the fixing block (211) is inserted into the horizontal positioning hole (213).

6. The novel purification device as claimed in claim 1, wherein the bottom of the gravity column body (410) is tapered.