CN215390024U

CN215390024U - Centrifugal separation device for extracting animal plasma protein

Info

Publication number: CN215390024U
Application number: CN202121647705.4U
Authority: CN
Inventors: 王园园; 张懿; 陈晨; 牛晓娟; 祁喆
Original assignee: Zhongyuan Mukang Wuhan Testing Technology Service Co ltd
Current assignee: Zhongyuan Mukang Wuhan Testing Technology Service Co ltd
Priority date: 2021-07-19
Filing date: 2021-07-19
Publication date: 2022-01-04
Anticipated expiration: 2031-07-19

Abstract

The utility model discloses a centrifugal separation device for extracting animal plasma protein, which comprises a centrifugal bin body, wherein a protective fixing mechanism is movably arranged at the top of the centrifugal bin body, a heating reaction mechanism is arranged in the centrifugal bin body, a centrifugal driving mechanism with one end penetrating through and extending into the heating reaction mechanism is fixedly arranged on the inner bottom wall of the centrifugal bin body, the top of the centrifugal driving mechanism is sleeved with a fixing mechanism, and a loading mechanism with one end pipe extending to the bottom of the fixing mechanism is movably arranged at the top of the fixing mechanism. This centrifugal separation device that animal plasma protein drawed, through fixed establishment and protection fixed establishment's setting, fixed establishment can prevent that loading mechanism from taking place the displacement of small-amplitude in fixed establishment is inside, and protection fixed establishment makes loading mechanism can not rock from top to bottom, so, has improved loading mechanism's stability, just can not make the incomplete phenomenon of separation take place just can not influence animal plasma protein and draw the purity.

Description

Centrifugal separation device for extracting animal plasma protein

Technical Field

The utility model relates to the technical field of animal plasma protein extraction, in particular to a centrifugal separation device for extracting animal plasma protein.

Background

The plasma protein refers to a protein part in plasma, the plasma protein is a general term of various proteins, the plasma protein can be divided into several components such as albumin, globulin and fibrinogen, and in modern biological science research, the plasma protein of animals is generally extracted for research to analyze pathology, medicament development and the like.

At present, most of the existing centrifugal separation devices for extracting animal plasma proteins place test tubes directly into the devices for centrifugation, for example, patent with application number CN202011521555.2 discloses a plasma collection device using centrifugal separation method, which is characterized in that a fixed shaft is connected with a locking column in a penetrating way, the outer side of each locking column is fixedly connected with a centrifugal separation storage box, a separation tube body is placed on the inner side of a storage groove of the centrifugal separation storage box, and the centrifugal separation is performed on plasma in the separation tube body by controlling the rotating speed of a rotating disc for centrifugal separation through a computer.

However, the direct placement method can lead to the situation that the test tube cannot be well fixed in the centrifugal separation process, the incomplete separation phenomenon can occur, the working quality is reduced, and the purity of the animal plasma protein extraction is affected.

SUMMERY OF THE UTILITY MODEL

The utility model provides a centrifugal separation device for extracting animal plasma protein, aiming at the technical problems in the prior art, and solving the problem of unstable fixation of the existing centrifugal separation device.

The technical scheme for solving the technical problems is as follows:

the centrifugal separation device for extracting the animal plasma protein comprises a centrifugal bin body, wherein a protective fixing mechanism is movably mounted at the top of the centrifugal bin body, a heating reaction mechanism is arranged in the centrifugal bin body, a centrifugal driving mechanism with one end penetrating through and extending into the heating reaction mechanism is fixedly mounted on the inner bottom wall of the centrifugal bin body, the top of the centrifugal driving mechanism is sleeved with the fixing mechanism, and a loading mechanism with one end pipe extending to the bottom of the fixing mechanism is movably mounted at the top of the fixing mechanism;

the fixing mechanism comprises a positioning sleeve, a placing disc, a perforation, a pressure spring and a fixing clamp plate, wherein the positioning sleeve is fixedly arranged outside the positioning sleeve and is used for placing the disc, the top of the placing disc is provided with a perforation, one end of the perforation runs through the perforation and extends to the bottom of the placing disc, the pressure spring is fixedly arranged on the left side and the right side of the inner wall of the perforation, and the fixing clamp plate is fixedly arranged on one side, opposite to the pressure spring.

Further, the centrifugal bin body comprises a protective shell, a placing hole, a refrigerating inner machine and a heat dissipation outer machine, the placing hole is formed in the top of the protective shell, one end of the placing hole penetrates through the protective shell and extends into the protective shell, the refrigerating inner machine is fixedly mounted on the right side of the inner wall of the protective shell, and the heat dissipation outer machine is fixedly mounted on the right side of the protective shell.

Further, protection fixed establishment includes top cap, electric putter and positioning pressure plate, the top fixed mounting of top cap has one end to run through and extend to the inside electric putter of top cap, electric putter's output fixed mounting has positioning pressure plate.

Further, heating reaction mechanism includes diaphragm, heating plate and reaction storehouse, the inside of protective housing and the below fixed mounting that is located the refrigeration interior machine have the diaphragm, the top fixed mounting of diaphragm has the heating plate, the top fixed mounting of heating plate has one end and protective housing fixed connection's reaction storehouse.

Further, centrifugal drive mechanism includes centrifugal motor and drive rotor, centrifugal motor's output fixed mounting has one end to run through diaphragm, heating plate and reaction storehouse and extend to the inside drive rotor in reaction storehouse.

Further, loading mechanism includes stopper and separation test tube, place the top of dish and place the stopper that is located the perforation top, the bottom fixed mounting of stopper has one end to run through the perforation and extend to the separation test tube that places dish below and one end and solid fixed splint and contact.

Furthermore, the positioning pressing plate is matched with the placing disc, and the fixing mechanism is made of stainless steel.

Further, the reaction bin is located outside the placing hole, and the outer wall of the transverse plate is matched with the inner wall of the protective shell.

Furthermore, the refrigerating inner machine is matched with the heat dissipation outer machine, and pillars are fixedly mounted at four corners of the bottom of the protective shell.

Compared with the prior art, the technical scheme of the application has the following beneficial technical effects:

1. this centrifugal separation device that animal plasma protein drawed, through fixed establishment and protection fixed establishment's setting, fixed establishment can prevent that loading mechanism from taking place the displacement of small-amplitude in fixed establishment is inside, and protection fixed establishment makes loading mechanism can not rock from top to bottom, so, has improved loading mechanism's stability, thereby just can not make the incomplete phenomenon of separation take place to lead to the operating mass to reduce, just can not influence animal plasma protein and draw the purity yet.

2. This centrifugal separation device that animal plasma protein drawed through the setting of heating plate, refrigeration interior machine and the outer machine of heat dissipation, makes loading mechanism's centrifugal temperature can freely be adjusted, also can save the animal plasma protein and place after the loading mechanism centrifugation is accomplished, can not make it rotten because of the high temperature, made things convenient for the user to use.

Drawings

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is an enlarged view taken at A of FIG. 1 in accordance with the present invention;

FIG. 3 is an enlarged view of the utility model at B of FIG. 1;

FIG. 4 is a top view of the securing mechanism of the present invention;

fig. 5 is a front view of the present invention.

In the drawings, the components represented by the respective reference numerals are listed below:

1 centrifugal cabin body, 101 protective shell, 102 placing hole, 103 refrigeration inner machine, 104 heat dissipation outer machine, 2 protection fixing mechanism, 201 top cover, 202 electric push rod, 203 positioning pressing plate, 3 heating reaction mechanism, 301 horizontal plate, 302 heating plate, 303 reaction cabin, 4 centrifugal driving mechanism, 401 centrifugal motor, 402 driving rotor, 5 fixing mechanism, 501 positioning sleeve, 502 placing plate, 503 perforation, 504 pressure spring, 505 fixing clamping plate, 6 loading mechanism, 601 limiting block, 602 separation test tube.

Detailed Description

The principles and features of this invention are described below in conjunction with the following drawings, which are set forth by way of illustration only and are not intended to limit the scope of the utility model.

Referring to fig. 1-5, the centrifugal separation device for extracting animal plasma protein in this embodiment includes a centrifugal chamber 1, a heating reaction mechanism 3 is disposed inside the centrifugal chamber 1, a centrifugal driving mechanism 4 having one end penetrating through and extending into the heating reaction mechanism 3 is fixedly installed on an inner bottom wall of the centrifugal chamber 1, a fixing mechanism 5 is sleeved on a top of the centrifugal driving mechanism 4, and a loading mechanism 6 having an end pipe and extending to a bottom of the fixing mechanism 5 is movably installed on a top of the fixing mechanism 5.

Wherein, fixed establishment 5 includes position sleeve 501, place dish 502, perforation 503, compression spring 504 and solid fixed splint 505, the outside fixed mounting of position sleeve 501 places dish 502, place the top of dish 502 and offer one end and run through and extend to the perforation 503 of placing the dish 502 bottom, the equal fixed mounting in the inner wall left and right sides of perforation 503 has compression spring 504, the relative one side fixed mounting of compression spring 504 has solid fixed splint 505, through placing loading mechanism 6 into perforation 503, make inside compression spring 504 drive solid fixed splint 505 and fix loading mechanism 6, prevented that loading mechanism 6 from taking place the displacement of small amplitude, will install the fixed establishment 5 and the mutual installation of centrifugal drive mechanism 4 of loading mechanism 6, then open protection fixed establishment 2 and place dish 502 support with separation test tube 602, make loading mechanism 6 can not rock from top to bottom.

In this embodiment, the centrifugal cabin body 1 includes the protective housing 101, place hole 102, the outer machine 104 of refrigeration indoor unit 103 and heat dissipation, one end has been seted up at the top of protective housing 101 and has been run through and extend to the inside hole 102 of placing of protective housing 101, the inner wall right side fixed mounting of protective housing 101 has the refrigeration indoor unit 103, the right side fixed mounting of protective housing 101 has the outer machine 104 that dispels the heat, the setting up of refrigeration indoor unit 103 and the outer machine 104 that dispels the heat can make the 6 temperatures of loading mechanism by quick cooling, let centrifugal temperature can freely adjust, make loading mechanism 6 store the animal plasma protein after the centrifugation is accomplished and place.

In order to avoid the up-and-down shaking of the loading mechanism during centrifugation, the protection fixing mechanism 2 is further arranged in the centrifugal loading mechanism, the protection fixing mechanism comprises a top cover 201, an electric push rod 202 and a positioning pressing plate 203, the electric push rod 202 with one end penetrating and extending into the top cover 201 is fixedly installed at the top of the top cover 201, the positioning pressing plate 203 is fixedly installed at the output end of the electric push rod 202, the limiting block 601 and the placing disc 502 are abutted through the positioning pressing plate 203, and the up-and-down shaking of the loading mechanism 6 during centrifugation is avoided.

Heating reaction mechanism 3 includes diaphragm 301, heating plate 302 and reaction bin 303, and the below fixed mounting that the inside of protective housing 101 just is located refrigeration indoor unit 103 has diaphragm 301, and the top fixed mounting of diaphragm 301 has heating plate 302, and the top fixed mounting of heating plate 302 has one end and protective housing 101 fixed connection's reaction bin 303, and the setting up of heating plate 302 makes loading mechanism 6 can be by free heating, need not use extra equipment, reduces user working strength.

The centrifugal driving mechanism 4 comprises a centrifugal motor 401 and a driving rotor 402, wherein the output end of the centrifugal motor 401 is fixedly provided with the driving rotor 402, one end of which penetrates through the transverse plate 301, the heating plate 302 and the reaction bin 303 and extends into the reaction bin 303.

Loading mechanism 6 includes stopper 601 and separation test tube 602, places the stopper 601 that is located perforation 503 top at the top of placing dish 502, and the bottom fixed mounting of stopper 601 has one end to run through perforation 503 and extend to the separation test tube 602 that places dish 502 below and one end and fixed splint 505 contact, and the setting of stopper 601 has avoided separation test tube 602 to fall from perforation 503 when centrifuging.

Specifically, when the utility model is used, the positioning pressing plate 203 and the placing disc 502 need to be set in a form matched with each other, the fixing mechanism 5 is made of stainless steel, and the fixing mechanism 5 is made of stainless steel, so that the utility model has the capabilities of resisting corrosion and pressure and can be used for a long time.

In this embodiment, the reaction chamber 303 is located outside the placing hole 102, and the outer wall of the horizontal plate 301 is matched with the inner wall of the protective shell 101.

In addition, in order to quickly cool the centrifugal separation device and avoid the influence of the internal temperature on the blood product after centrifugal separation, the centrifugal separation device is provided with the refrigerating inner machine 103 matched with the heat dissipation outer machine 104, the four corners of the bottom of the protective shell 101 are fixedly provided with the supporting columns, the refrigerating inner machine 103 continuously guides out the internal high temperature and transmits the internal high temperature to the heat dissipation outer machine 104, and the heat dissipation outer machine 104 dissipates the temperature, so that the quick cooling of the interior of the reaction bin 303 is realized.

When animal plasma protein needs to be centrifugally extracted, the fixing mechanism 5 is taken down, the positioning sleeve 501 is separated from the driving rotor 402, the loading mechanism 6 is placed into the through hole 503, the internal pressure spring 504 drives the fixing clamping plate 505 to fix the loading mechanism 6, and the small-amplitude displacement of the loading mechanism 6 is prevented, at the moment, the fixing mechanism 5 provided with the loading mechanism 6 is mutually installed with the driving rotor 402, then the electric push rod 202 is opened to drive the positioning pressing plate 203 to abut against the limiting block 601 on the separation test tube 602 with the placing plate 502, so that the loading mechanism 6 cannot shake up and down, the stability of the loading mechanism 6 is improved, the phenomenon of incomplete separation cannot occur, the working quality is reduced, and the extraction purity of the animal plasma protein cannot be influenced.

Then, make loading mechanism 6 can be by free heating through the temperature of adjustment heating plate 302, the setting of rethread refrigeration inner unit 103 and the outer machine 104 of heat dissipation can make loading mechanism 6 temperature by rapid cooling, lets centrifugal temperature can freely be adjusted, so, avoided the messenger to heat the cooling to loading mechanism 6 before the experiment, reduce user working strength, also can make loading mechanism 6 store the placement to animal plasma protein after the centrifugation is accomplished, can not make it rotten because of the high temperature.

The present invention is not limited to the above preferred embodiments, and any modifications, equivalent replacements, improvements, etc. within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. The centrifugal separation device for extracting the animal plasma protein is characterized by comprising a centrifugal cabin body (1), wherein a heating reaction mechanism (3) is arranged inside the centrifugal cabin body (1), a centrifugal driving mechanism (4) with one end penetrating through and extending into the heating reaction mechanism (3) is fixedly arranged on the inner bottom wall of the centrifugal cabin body (1), a fixing mechanism (5) is sleeved at the top of the centrifugal driving mechanism (4), and a loading mechanism (6) with one end pipe extending to the bottom of the fixing mechanism (5) is movably arranged at the top of the fixing mechanism (5);

fixed establishment (5) include position sleeve (501), place dish (502), perforation (503), compression spring (504) and solid fixed splint (505), the outside fixed mounting of position sleeve (501) has and places dish (502), the top of placing dish (502) is seted up one end and is run through and extend to the perforation (503) of placing dish (502) bottom, the equal fixed mounting in inner wall left and right sides of perforation (503) has compression spring (504), one side fixed mounting that compression spring (504) is relative has solid fixed splint (505).

2. The centrifugal separation device for animal plasma protein extraction according to claim 1, wherein the centrifugal bin body (1) comprises a protective shell (101), a placing hole (102), a refrigerating inner machine (103) and a heat dissipation outer machine (104), the placing hole (102) with one end penetrating through and extending into the protective shell (101) is formed in the top of the protective shell (101), the refrigerating inner machine (103) is fixedly installed on the right side of the inner wall of the protective shell (101), and the heat dissipation outer machine (104) is fixedly installed on the right side of the protective shell (101).

3. The centrifugal separation device for animal plasma protein extraction according to claim 1, wherein a protective fixing mechanism (2) is movably mounted at the top of the centrifugal cabin body (1), the protective fixing mechanism (2) comprises a top cover (201), an electric push rod (202) and a positioning pressure plate (203), the electric push rod (202) with one end penetrating through and extending into the top cover (201) is fixedly mounted at the top of the top cover (201), and the positioning pressure plate (203) is fixedly mounted at the output end of the electric push rod (202).

4. The centrifugal separation device for animal plasma protein extraction according to claim 2, wherein the heating reaction mechanism (3) comprises a transverse plate (301), a heating plate (302) and a reaction chamber (303), the transverse plate (301) is fixedly installed inside the protective casing (101) and below the refrigerating inner machine (103), the heating plate (302) is fixedly installed at the top of the transverse plate (301), and the reaction chamber (303) with one end fixedly connected with the protective casing (101) is fixedly installed at the top of the heating plate (302).

5. The centrifugal separation device for extracting the animal plasma protein according to claim 4, wherein the centrifugal driving mechanism (4) comprises a centrifugal motor (401) and a driving rotor (402), and the output end of the centrifugal motor (401) is fixedly provided with the driving rotor (402) with one end penetrating through the transverse plate (301), the heating plate (302) and the reaction chamber (303) and extending to the inside of the reaction chamber (303).

6. The centrifugal separation device for animal plasma protein extraction according to claim 1, wherein the loading mechanism (6) comprises a stopper (601) and a separation tube (602), the stopper (601) is placed on the top of the placing tray (502) and positioned above the perforation (503), and the bottom of the stopper (601) is fixedly provided with the separation tube (602) which has one end penetrating through the perforation (503) and extending to the lower part of the placing tray (502) and one end contacting with the fixed clamping plate (505).

7. The centrifugal separation device for animal plasma protein extraction according to claim 3, wherein the positioning pressure plate (203) is adapted to the placing tray (502), and the fixing mechanism (5) is stainless steel.

8. The centrifugal separation device for animal plasma protein extraction according to claim 4, characterized in that the reaction chamber (303) is located outside the placing hole (102), and the outer wall of the horizontal plate (301) is matched with the inner wall of the protective shell (101).

9. The centrifugal separation device for extracting animal plasma protein according to claim 2, characterized in that the refrigerating inner machine (103) and the heat radiating outer machine (104) are matched, and pillars are fixedly arranged at four corners of the bottom of the protective shell (101).