CN215328014U - Wrong appearance device is added in prevention - Google Patents
Wrong appearance device is added in prevention Download PDFInfo
- Publication number
- CN215328014U CN215328014U CN202120411708.1U CN202120411708U CN215328014U CN 215328014 U CN215328014 U CN 215328014U CN 202120411708 U CN202120411708 U CN 202120411708U CN 215328014 U CN215328014 U CN 215328014U
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- sample
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- plate
- card strip
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- 230000002265 prevention Effects 0.000 title claims abstract description 29
- 239000002184 metal Substances 0.000 claims abstract description 3
- 239000003086 colorant Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 abstract description 9
- 239000000443 aerosol Substances 0.000 abstract description 5
- 238000012864 cross contamination Methods 0.000 abstract description 5
- 238000001514 detection method Methods 0.000 abstract description 5
- 239000000523 sample Substances 0.000 description 63
- 238000002347 injection Methods 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- 239000011148 porous material Substances 0.000 description 5
- 208000015181 infectious disease Diseases 0.000 description 3
- 230000002458 infectious effect Effects 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- 241000711573 Coronaviridae Species 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 102000039446 nucleic acids Human genes 0.000 description 2
- 108020004707 nucleic acids Proteins 0.000 description 2
- 150000007523 nucleic acids Chemical class 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 208000003464 asthenopia Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 229920006351 engineering plastic Polymers 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 230000006920 protein precipitation Effects 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model provides a wrong sample adding prevention device which comprises a 96-hole plate, a wrong sample adding prevention thin plate and a plurality of clamping strips. The 96-well plate is provided with a plurality of sample application holes which are arranged in a plurality of rows. The anti-misplug sheet is provided with a plurality of hollow parts, and each hollow part corresponds to one row of sample adding holes. Each card strip detachably connect in prevent adding wrong appearance sheet metal, just each card strip covers corresponding one row of application of sample hole in the fretwork portion below that corresponds. In the application of sample in-process, because the existence of card strip for when carrying out the application of sample to a certain row of application of sample hole, the application of sample hole homoenergetic that other rows were arranged can be covered by the card strip that corresponds, and it plays the function that prevents the sample splash to a certain extent, thereby has reduced the cross contamination problem that leads to because of the existence of aerosol, has greatly improved the accuracy of experimental result from this. In addition, simple structure, convenient to use of this application, it can not additionally increase hospital and scientific research personnel's check-out time, has guaranteed detection efficiency from this.
Description
Technical Field
The utility model relates to the technical field of biological detection equipment, in particular to a wrong sample adding prevention device.
Background
A 96-well plate is a commonly used reaction vessel, and is widely used in clinical diagnosis, biological research, and the like in hospitals or scientific laboratories. By using the combined discharging gun, the high-flux automatic liquid operation instrument and software, the high-flux operation of biological samples such as protein precipitation, cell and human body fluid extraction, nucleic acid extraction and the like is realized, the sample processing efficiency is greatly improved, but because the automatic sample adding equipment is expensive, a part of hospitals or scientific research laboratories still adopt a manual sample adding method for operation.
In the former process of some special samples (such as infectious samples containing virus, etc.), the whole automatic operation can not be adopted to ensure the biological safety, and the detection of new coronavirus is the best example. When nucleic acid is extracted from a pharyngeal swab of a suspected novel coronavirus patient, the sample must be fully and uniformly mixed in a biological safety workbench in a vortex mode, and the sample is added into the holes of a 96-hole plate one by one in a manual sample adding mode so as to prevent the pollution of the virus to the environment. However, when the existing 96-well plate is used for sample loading, all sample loading holes are exposed in the environment, and when a sample is splashed, cross contamination between the sample loading holes is easily caused due to existence of aerosol, so that an experimental result is inaccurate.
SUMMERY OF THE UTILITY MODEL
In view of the problems in the background art, the present invention is directed to a missample prevention device, which has a function of preventing a sample from being sprayed, thereby reducing the problem of cross-contamination caused by the presence of aerosol, and greatly improving the accuracy of an experimental result.
In order to achieve the above object, the present invention provides a misloading prevention device for being disposed on a 96-well plate, wherein the 96-well plate is provided with a plurality of loading holes, and the plurality of loading holes are arranged in a plurality of rows. The wrong sample adding prevention device comprises a wrong sample adding prevention thin plate and a plurality of clamping strips. The anti-misplug sheet is provided with a plurality of hollow parts and is used for being matched with a 96-hole plate and enabling each hollow part to correspond to one row of sample adding holes. Each card strip detachably connect in prevent adding wrong appearance sheet metal, just each card strip covers corresponding one row of application of sample hole in the fretwork portion below that corresponds.
In the mis-proof device according to some embodiments, the mis-proof sheet includes an upper wall positioned above the 96-well plate and a side wall positioned outside the 96-well plate. The plurality of hollow parts are arranged on the upper wall and are arranged at intervals.
In the misplug prevention device according to some embodiments, the side wall is provided with a plurality of pairs of mounting parts, and two mounting parts in each pair of mounting parts are oppositely arranged and are used for mounting a corresponding clamping strip together.
In the mis-proof device according to some embodiments, both of the mounting portions of each of the pairs of mounting portions are through-hole structures.
In the mis-proof sampling device according to some embodiments, each of the mounting portions has a rectangular-shaped structure.
In the misloading prevention device according to some embodiments, each of the card strips is a fully transparent or translucent-like structure.
In the mis-proof sampling device according to some embodiments, the plurality of card strips are coated with different colors on the outer sides thereof, respectively.
The utility model has the following beneficial effects:
the application prevents the application of sample in-process that adds wrong appearance device, because the existence of card strip, make when carrying out the application of sample to a certain row of application of sample hole, the application of sample hole homoenergetic that other rows are arranged can be covered by the card strip that corresponds, it plays the function that prevents the sample splash to a certain extent, thereby reduced the cross contamination problem that leads to because of the existence of aerosol, thereby greatly improved the accuracy of experimental result, can also play certain guard action to operating personnel simultaneously in drawing the in-process to the application of sample application of infectious sample. In addition, the prevention of this application adds wrong appearance device simple structure, convenient to use, it can not additionally increase hospital and scientific research personnel's check-out time, has guaranteed detection efficiency from this.
Drawings
Fig. 1 is a schematic structural view of the misloading prevention device of the present invention disposed on a 96-well plate.
Fig. 2 is a schematic structural view of fig. 1 after one of the card strips is extracted.
Fig. 3 is an exploded view of the misloading prevention apparatus of the present invention.
Wherein the reference numerals are as follows:
1 side wall of wrong sample adding preventing thin plate 13
11 hollowed-out part 2 clamping strip
12 upper wall H96 pore plate
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are some embodiments of the present application, but not all embodiments.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs; the terminology used in the description of the application herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application; the terms "including" and "having," and any variations thereof, in the description and claims of this application and the description of the above figures are intended to cover non-exclusive inclusions.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.
The term "plurality" as used herein refers to more than two (including two), and also "multiple rows". The mis-proof apparatus according to the present application will be described in detail with reference to the accompanying drawings.
The wrong appearance device is added in prevention of this application is used for setting up on 96 orifice plate H to add the sample to a plurality of application of sample holes on 96 orifice plate H. Wherein, 96 orifice plate H is provided with a plurality of application wells, a plurality of application wells arrange into multirow.
Referring to fig. 1, the mispairing prevention apparatus of the present application includes a mispairing prevention sheet 1 and a plurality of clamping strips 2. The anti-misplug thin plate 1 is provided with a plurality of hollow parts 11, and each clamping strip 2 is detachably connected to the anti-misplug thin plate 1.
Before the application of sample to a plurality of application of sample holes on 96 orifice plate H, can directly install the prevention of this application with wrong appearance device on 96 orifice plate H, prevent adding wrong appearance thin plate 1 and 96 orifice plate H cooperation this moment and make each fretwork portion 11 corresponds a row of application of sample holes, and each card strip 2 covers a row of application of sample holes in the fretwork portion 11 below that corresponds. And because the installation between the wrong sample prevention device and the 96-well plate H is simple, the time cost is not increased.
The wrong sample adding prevention device is arranged behind the 96-pore plate H but before sample adding is carried out on a plurality of sample adding holes in the 96-pore plate H, and the plurality of clamping strips 2 respectively cover a row of corresponding sample adding holes in the 96-pore plate H, so that the environmental consistency in all the sample adding holes in the 96-pore plate H before sample adding can be ensured. When the device is used, a sample is firstly sucked by the sample injector, then the clamping strips 2 on each row are sequentially and completely extracted in a drawing mode, sample injection is carried out on the sample injection holes in the row one by one (or the clamping strips 2 on each row are subjected to sample injection while being drawn), and after all sample injection of the sample injection holes in the row is finished, the clamping strips 2 are inserted back into the corresponding hollow parts 11 on the anti-misloading thin plate 1. Thus, all rows of wells on the 96-well plate H were filled in sequence. And after the sample adding of all the sample adding holes on the 96-hole plate H is finished, the whole sample adding error prevention device is removed.
In-process to carrying out the application of sample to 96 orifice plate H, because the existence of card strip 2 for when carrying out the application of sample to a certain row of application of sample hole, the application of sample hole homoenergetic of other rows can be covered by card strip 2, it has the function that prevents the sample splash to a certain extent, thereby cross contamination problem that leads to has reduced because of the existence of aerosol, thereby greatly improved the accuracy of experimental result, can also play certain guard action to operating personnel in drawing the in-process to the application of sample of infectious sample simultaneously. In addition, the prevention of this application adds wrong appearance device simple structure, convenient to use, it can not additionally increase hospital and scientific research personnel's check-out time, has guaranteed detection efficiency from this.
In some embodiments, the anti-misloading sheet 1 includes an upper wall 12 and a side wall 13. The upper wall 12 is located above the 96-well plate H, the side wall 13 is located outside the 96-well plate H, and the plurality of hollow parts 11 are disposed on the upper wall 12 and arranged at intervals on the upper wall 12. At this moment, the upper wall 12 of the anti-misplugging sample thin plate 1 and the side wall 13 form a containing cavity together, the anti-misplugging sample thin plate 1 is sleeved on and limited on the 96-hole plate H through the containing cavity (namely, at least part of the 96-hole plate H is limited in the containing cavity), so that the anti-misplugging sample thin plate 1 and the 96-hole plate H can be tightly buckled together, the connection stability between the anti-misplugging sample thin plate 1 and the 96-hole plate H in the sample adding process is ensured, the problem of misplugging samples caused by shaking is further ensured, and the accuracy of an experimental result is further improved.
In some embodiments, the side wall 13 of the anti-aliasing thin plate 1 is provided with a plurality of pairs of mounting parts 14, two mounting parts 14 of each pair of mounting parts 14 are oppositely arranged and are mounted together to correspond to one card strip 2, so that the card strip 2 can be drawn out or inserted back into the corresponding pair of mounting parts 14.
In some embodiments, each mounting portion 14 may be formed as a rectangular-shaped structure.
In some embodiments, two installation parts 14 of each pair of installation parts 14 on the anti-misloading thin plate 1 are through-hole structures, and each clamping strip 2 can be arbitrarily drawn at two sides in the length direction.
In some embodiments, in order to facilitate viewing of the wells in the 96-well plate H to prevent misloading, each strip 2 is preferably a fully transparent or translucent structure.
In some embodiments, each card strip 2 may be of a plate-like construction and made of plastic. Further, each card strip 2 is made of engineering plastic (abbreviated as PV in english).
In some embodiments, in order to reduce the mismatching problem caused by the visual fatigue, the outer sides of the plurality of card strips 2 are respectively coated with different colors. In the application of sample in-process, can arrange the application of sample gradually based on the colour difference in proper order to avoid the condition of repeated application of sample, improved the accuracy of application of sample efficiency and experimental result from this.
Claims (7)
1. A misplug prevention device is arranged on a 96-hole plate (H), the 96-hole plate (H) is provided with a plurality of sample adding holes, and the sample adding holes are arranged in a plurality of rows, and the misplug prevention device is characterized by comprising a misplug prevention thin plate (1) and a plurality of clamping strips (2);
the anti-misloading sample thin plate (1) is provided with a plurality of hollowed-out parts (11), and the anti-misloading sample thin plate (1) is used for being matched with a 96-hole plate (H) and enabling each hollowed-out part (11) to correspond to a row of sample loading holes;
each card strip (2) detachably connect in prevent adding wrong appearance sheet metal (1), just each card strip (2) covers corresponding one row of application of sample hole in the fretwork portion (11) below that corresponds.
2. The mis-proof loading device as claimed in claim 1,
the misplug-preventing thin plate (1) comprises an upper wall (12) and a side wall (13), wherein the upper wall (12) is positioned above the 96-well plate (H), and the side wall (13) is positioned outside the 96-well plate;
the plurality of hollow parts (11) are arranged on the upper wall and are arranged at intervals.
3. The mispairing prevention device according to claim 2, wherein the side wall (13) is provided with a plurality of pairs of mounting portions (14), and two mounting portions (14) of each pair of mounting portions (14) are oppositely arranged and together mount a corresponding one of the clamping strips (2).
4. The mis-proof device as recited in claim 3, wherein both of the mounting portions (14) of each pair of mounting portions (14) are through-hole structures.
5. A misloading prevention device according to claim 3, wherein each mounting portion (14) is of a rectangular configuration.
6. The mispairing prevention device of claim 1, wherein each card strip (2) is of a fully transparent or translucent structure.
7. The mispairing prevention device according to claim 1, wherein the plurality of card strips (2) are respectively coated with different colors.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120411708.1U CN215328014U (en) | 2021-02-25 | 2021-02-25 | Wrong appearance device is added in prevention |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120411708.1U CN215328014U (en) | 2021-02-25 | 2021-02-25 | Wrong appearance device is added in prevention |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215328014U true CN215328014U (en) | 2021-12-28 |
Family
ID=79581901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202120411708.1U Expired - Fee Related CN215328014U (en) | 2021-02-25 | 2021-02-25 | Wrong appearance device is added in prevention |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN215328014U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112111369A (en) * | 2020-08-26 | 2020-12-22 | 右江民族医学院附属医院 | Anti-pollution shielding platform for extracting blood DNA by detecting genes of thalassemia |
-
2021
- 2021-02-25 CN CN202120411708.1U patent/CN215328014U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112111369A (en) * | 2020-08-26 | 2020-12-22 | 右江民族医学院附属医院 | Anti-pollution shielding platform for extracting blood DNA by detecting genes of thalassemia |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20211228 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |