CN215310357U - Strong acid cation filler SPE post convenient to elute - Google Patents
Strong acid cation filler SPE post convenient to elute Download PDFInfo
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- CN215310357U CN215310357U CN202021789478.4U CN202021789478U CN215310357U CN 215310357 U CN215310357 U CN 215310357U CN 202021789478 U CN202021789478 U CN 202021789478U CN 215310357 U CN215310357 U CN 215310357U
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Abstract
The utility model relates to the technical field of chemical experimental devices, in particular to a strong acid cation filler SPE column convenient to elute, wherein an elution tube is arranged at the bottom end of the column body and is provided with external threads, the elution tube is in threaded connection with an installation cap, the top end of the column body is provided with internal threads, and the top end of the column body is in threaded connection with a connection cap; the mounting cap comprises a first threaded pipe, the first threaded pipe is matched with the elution pipe, the first threaded pipe is fixedly connected with a first rubber sleeve, the tail end of the first rubber sleeve is fixedly connected with a positioning ring, the outer end of the first rubber sleeve is sleeved with a clamping ring, the connecting cap comprises a second threaded pipe, the second threaded pipe is in threaded connection with the cylinder body, the second threaded pipe is fixedly connected with a second rubber sleeve, the second rubber sleeve is fixedly connected with an outer pipe, and the outer pipe is sleeved with the cylinder body; the utility model has the advantages of convenient operation, flexible use, strong adaptability and convenient disassembly, can be adjusted according to the use condition and is more suitable for the use requirement.
Description
Technical Field
The utility model relates to the technical field of chemical experimental devices, in particular to a strong-acid cation filler SPE column convenient to elute.
Background
In the quantitative analysis of harmful components in complex matrix samples such as food, environment, biological samples and the like, the matrix has a large influence on the quantitative result, and usually needs purification treatment to reduce the interference of the matrix. Purifying the sample by a solid phase extraction column;
the solid phase extraction is a sample pretreatment technology developed in the late stage of the seventy-eight years of the 19 th century, can be combined with a liquid phase chromatography technology, a gas phase chromatography technology, a mass spectrum technology and other technologies, can reduce sample matrix interference, improves detection sensitivity, and is widely applied to separation, purification and enrichment of samples in the fields of environment, pharmacy, clinical medicine, food and the like.
The SPE technology is a physical extraction process including a liquid phase and a solid phase, and mainly separates a component to be detected from an interfering component by the acting force between a bonding functional group on a solid adsorbent and a target analyte, thereby achieving the purpose of separating and enriching a sample. The conventional method is to make the liquid sample solution pass through the adsorbent to retain the substance to be detected, wash out the impurities by selecting a solvent with proper strength, and then rapidly elute the substance to be detected by using a small amount of solvent, thereby achieving the purpose of rapid separation, purification and concentration.
The existing solid-phase extraction column has poor sealing effect when pressurizing, vacuumizing or centrifuging, needs to be equipped with a device for vacuumizing, has poor adaptability with the existing vacuum pump, cannot be adjusted according to the connecting position of the existing vacuum pump connecting pipe and the liquid storage device, and is inconvenient to use.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide the SPE column which is convenient to operate, strong in adaptability, good in sealing performance, convenient to disassemble and assemble and convenient to elute and is a strong-acid cation filler.
In order to achieve the purpose, the utility model provides the following technical scheme: a strong acid cation filler SPE column convenient for elution is provided, wherein an elution pipe is arranged at the bottom end of the column body, an external thread is arranged on the elution pipe, an installation cap is connected with the elution pipe through a thread, an internal thread is arranged at the top end of the column body, and a connection cap is connected with the top end of the column body through a thread;
the installation cap includes first screwed pipe, first screwed pipe with elution pipe looks adaptation, the first rubber sleeve of first screwed pipe fixedly connected with, first rubber sleeve tail end fixedly connected with holding ring, the snap ring has been cup jointed to first rubber sleeve outer end.
Further, the elution pipe is provided with a pressure valve and a pressure gauge.
Further, the connecting cap comprises a second threaded pipe, the second threaded pipe is in threaded connection with the cylinder, a second rubber sleeve is fixedly connected with the second threaded pipe, an outer pipe is fixedly connected with the second rubber sleeve, and the outer pipe is sleeved with the cylinder.
Furthermore, the outer end of the connecting cap is detachably connected with a cover body.
Furthermore, the snap ring includes first snap ring and second snap ring, the second snap ring with first snap ring activity cup joints.
Furthermore, the first snap ring is provided with an elastic sheet, and a through hole with a trapezoidal cross section is formed in the second snap ring.
Furthermore, the positioning ring is formed by combining two metal semi-rings.
Further, the cylinder includes upper cylinder and lower cylinder, upper cylinder with lower cylinder threaded connection, lower cylinder is equipped with the arris, lower cylinder has the packing board through arris swing joint, the packing board is strong acid cation packing board.
Furthermore, the filler plate comprises an upper sieve plate, a lower sieve plate and a filler positioned between the upper sieve plate and the lower sieve plate.
Further, the elution pipe is arranged at the bottom end of the packing plate.
Further, the cylinder is equipped with the liquid outlet, the diameter of liquid outlet is less than the cylinder.
Furthermore, the upper end of the column body is provided with an opening.
Furthermore, the liquid outlet all is equipped with the head.
Compared with the prior art, the utility model has the beneficial effects that: the processing device capable of realizing bending of the small circular plate of the device plate is reasonable in structure and has the following advantages:
(1) the utility model can adapt to the connecting pipe of a common liquid storage device and a vacuum pump by arranging the connecting cap and the mounting cap, and can achieve better sealing effect, the positioning ring can facilitate the connection of the connecting pipe of the vacuum pump, and can achieve positioning effect, the clamping ring can enable the device to have better sealing effect, the first threaded pipe can stably connect the mounting cap to the elution pipe, and can randomly adjust the connecting position of the mounting cap on the elution pipe, and extend or shorten the extension length of the first rubber sleeve, thereby better adapting to the installation of the connecting pipe of the vacuum pump, and the first rubber sleeve has elasticity, can adapt to the connecting pipe of the vacuum pump with a diameter larger than that of the elution pipe 2 and the connecting pipe of the vacuum pump with a diameter smaller than that of the elution pipe to a certain extent, is more flexible to use, can increase the adapting range of a vacuum suction device, and the arrangement of the connecting cap can also adapt to the installation of the liquid storage device with a larger or thinner diameter, the second rubber sleeve can play a better sealing effect under the action of elastic deformation, so that the device can adapt to liquid storage devices with different interfaces.
(2) The device has the advantages of more flexible use, convenient operation and disassembly, convenient installation and placement, can be adjusted according to the use condition, and is more suitable for the use requirement.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic structural view of the disassembled mounting cap and the connecting cap of the present invention;
FIG. 3 is a schematic structural diagram of a snap ring of the present invention;
FIG. 4 is a schematic structural diagram II of the snap ring of the present invention; .
FIG. 5 is a schematic structural diagram III of a snap ring according to the present invention.
In the figure: the device comprises a column body-1, an elution tube-2, an installation cap-3, a connecting cap-4, a first threaded tube-5, a first rubber sleeve-6, a positioning ring-7, a snap ring-8, a second threaded tube-9, a second rubber sleeve-10, an outer tube-11, a cover body-12, a first snap ring-13, a second snap ring-14, a spring sheet-15, a through hole-16, an upper column body-17, a packing plate-18, a liquid outlet-19 and a lower column body-20.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-4, a strong acid cation filler SPE column convenient for elution comprises a column body 1, wherein the column body 1 is provided with a liquid outlet 19, the diameter of the liquid outlet 19 is smaller than that of the column body 1, the bottom end of the column body 1 is provided with an elution pipe 2, the elution pipe 2 can be connected with a vacuum pump, a solid phase extraction process is completed under the action of vacuum pressure, and the effects of sample separation, enrichment and extraction are achieved;
the mounting cap 3 comprises a first threaded pipe 5, the first threaded pipe 5 is matched with the elution pipe 2, the first threaded pipe 5 is fixedly connected with a first rubber sleeve 6, the tail end of the first rubber sleeve 6 is fixedly connected with a positioning ring 7, the positioning ring 7 is formed by combining two metal semi-rings, the outer end of the first rubber sleeve 6 is sleeved with a clamping ring 8, the positioning ring 7 is arranged to prevent the edge of the first rubber sleeve 6 from turning or deforming when the first rubber sleeve 6 is connected with a vacuum pump connecting pipe to influence the connection process, the positioning ring 7 is arranged to facilitate the connection of the vacuum pump connecting pipe and the first rubber sleeve 6, the positioning effect can be effectively achieved, the first rubber sleeve 6 can be tightly connected with the vacuum pump connecting pipe through the clamping ring 8, so that the mounting cap has a good sealing effect, the first threaded pipe 5 can stably connect the first rubber sleeve 6 to the elution pipe 2, and the connection position of the mounting cap 3 on the elution pipe 2 can be adjusted at will, thereby extension or shorten the extension length of first rubber sleeve 6 to adapt to the installation of vacuum pump connecting pipe better, and first rubber sleeve 6 has elasticity, can adapt to the diameter to a certain extent and be greater than the 2 internal diameters of elution pipe, but the internal diameter is less than the vacuum pump connecting pipe of 2 external diameters of elution pipe, can cup joint first rubber sleeve 6 and install in vacuum pump connecting pipe outer end, uses comparatively in a flexible way, can increase vacuum suction device's accommodation.
The connecting cap 4 comprises a second threaded pipe 9, the second threaded pipe 9 is in threaded connection with the cylinder 1, a second rubber sleeve 10 is fixedly connected with the second threaded pipe 9, an outer pipe 11 is fixedly connected with the second rubber sleeve 10, the outer pipe 11 is sleeved with the cylinder 1, the outer end of the connecting cap 4 is detachably connected with a cover body 12, the second rubber sleeve 10 can play a role in sealing and can play a good role in the extraction process, the outer pipe 11 is made of rigid or brittle materials such as glass and has poor deformation capability, the upper end of the second rubber sleeve 10 can be sleeved on the cylinder 1 all the time due to the arrangement of the outer pipe 11, the second rubber sleeve 10 can be prevented from being restored to a vertical state, the second rubber sleeve 10 is kept to turn outwards, the outer pipe 11 can slide outside the cylinder 1, when the cover body 12 or the liquid storage device is installed to enable the second rubber sleeve 10 to extrude seriously, the outer pipe 11 can slide downwards, when second rubber sleeve 10 did not receive the extrusion, outer tube 11 can upwards slide slightly, is convenient for connect cap 4 and lid 12 or the thick stock solution device's of diameter installation, and second rubber sleeve 10 can play better sealed effect under elastic deformation's effect, makes the stock solution device of device adaptation different interfaces.
The snap ring 8 comprises a first snap ring 13 and a second snap ring 14, the second snap ring 14 is movably sleeved with the first snap ring 13, the first snap ring 13 is provided with an elastic sheet 15, a through hole 16 with a trapezoidal cross section is arranged in the second snap ring 14, the length of the through hole 16 is half of that of the elastic sheet 15, when the second snap ring 14 moves towards the first snap ring 13, the elastic sheet 15 of the first snap ring 13 can be gradually folded under the action of the through hole 16, when the second snap ring 14 is sleeved to the middle position of the elastic sheet 15, the elastic sheet 15 can be folded to the minimum diameter of the through hole 16 under the elastic action, when the second snap ring 14 is sleeved to the innermost end of the elastic sheet 15, under the action of the through hole 16, the elastic sheet 15 can be continuously folded towards the axle centers of the first snap ring 13 and the second snap ring 14, so that the outermost end of the elastic sheet 15 can be folded to the minimum, thereby pressing the first rubber sleeve 6 to deform, when the diameter of the vacuum pump connecting pipe is smaller than that of the first rubber sleeve 6, under the action of the clamping ring 8, the first rubber sleeve 6 can be tightly attached to a vacuum pump connecting pipe, so that the first rubber sleeve 6 and the vacuum pump connecting pipe are sealed;
if the diameter of the vacuum pump connecting pipe is larger than that of the first rubber sleeve 6, the clamping ring 8 can be detached, and the vacuum pump connecting pipe is more convenient to be connected with the first rubber sleeve 6.
The column body 1 comprises an upper column body 17 and a lower column body 20, the upper column body 17 is in threaded connection with the lower column body 20, the lower column body 20 is provided with edges, the lower column body 20 is movably connected with a packing plate 18 through the edges, the packing plate 18 is a strong acid cation packing plate, a filter screen 17 is arranged and can filter impurities in reaction liquid, the strong acid cation packing plate is a widely used cation packing, hydrogen in acid is cationized to generate coulomb force with sample liquid so as to adsorb target compounds in the sample liquid, the packing plate 18 can be eluted by a solvent after extraction, impurities in the packing plate 18 are removed, so that the packing plate 18 can be reused, the upper column body 17 and the lower column body 20 are separated so as to facilitate the replacement of the packing plate 18, when the activity of the packing plate 18 is insufficient and needs to be replaced, the upper column body 17 can be detached, the filler plate 18 is taken out to be treated and regenerated in the modes of solution soaking and the like, so that the energy is saved and the environment is protected.
The elution pipe 2 is arranged at the bottom end of the packing plate 18, so that the speed of sample liquid or eluent and the like flowing through the packing plate 18 can be increased, and the extraction and enrichment rate can be increased.
The working principle is as follows: when in use, a worker connects the vacuum pump connecting pipe with the mounting cap 3, the first rubber sleeve 6 is sleeved on the vacuum pump connecting pipe by moving the positioning ring 7, if the diameter of the vacuum pump connecting pipe is slightly larger than the diameter of the elution pipe 2, because the first rubber sleeve 6 has elasticity, the vacuum pump connecting pipe can support the first rubber sleeve 6 to enable the first rubber sleeve 6 to deform, so that the vacuum pump can be installed, if the diameter of the vacuum pump connecting pipe is slightly smaller than that of the elution pipe 2, the second snap ring 14 can move towards the first snap ring 13, the elastic sheet 15 of the first snap ring 13 can be gradually folded under the action of the through hole 16, so that the elastic sheet of the first clamping block 13 is applied with downward acting force and is plugged into the gap between the first rubber sleeve 6 and the through hole 16, thereby pressing the first rubber sleeve 6 to deform and tightly attach to the vacuum pump connecting pipe, and sealing the first rubber sleeve 6 and the vacuum pump connecting pipe; then, a worker connects the liquid storage device with the connecting cap 4, if the connecting position of the liquid storage device is thin, the liquid storage device can be directly inserted into the opening of the connecting cap 4, if the connecting position of the liquid storage device is thick, the second rubber sleeve 10 can be inserted into the connecting position of the liquid storage device, the second rubber sleeve 10 can play a good sealing effect under the action of elastic deformation, and the device can adapt to liquid storage devices with different interfaces;
if the size of the connecting pipe of the liquid storage device and the vacuum pump is matched with that of the column body 1, the connecting cap 4 and the mounting cap 3 are disassembled, and then the connecting device can be connected according to the connecting method of the existing device.
It will be evident to those skilled in the art that the utility model is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the utility model being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Claims (9)
1. A strong acid cation filler SPE column convenient for elution comprises a column body (1) and is characterized in that: the bottom end of the column body (1) is provided with an elution pipe (2), the elution pipe (2) is provided with an external thread, the elution pipe (2) is in threaded connection with a mounting cap (3), the top end of the column body (1) is provided with an internal thread, and the top end of the column body (1) is in threaded connection with a connecting cap (4);
installation cap (3) include first screwed pipe (5), first screwed pipe (5) with elution pipe (2) looks adaptation, first screwed pipe (5) first rubber sleeve of fixedly connected with (6), first rubber sleeve (6) tail end fixedly connected with holding ring (7), snap ring (8) have been cup jointed to first rubber sleeve (6) outer end.
2. A strongly acidic cation packed SPE column convenient for elution as claimed in claim 1 wherein: the connecting cap (4) comprises a second threaded pipe (9), the second threaded pipe (9) is in threaded connection with the cylinder (1), a second rubber sleeve (10) is fixedly connected with the second threaded pipe (9), an outer pipe (11) is fixedly connected with the second rubber sleeve (10), and the outer pipe (11) is sleeved with the cylinder (1).
3. A strongly acidic cation packed SPE column convenient for elution as claimed in claim 2 wherein: the outer end of the connecting cap (4) is detachably connected with a cover body (12).
4. A strongly acidic cation packed SPE column convenient for elution as claimed in claim 1 wherein: the snap ring (8) comprises a first snap ring (13) and a second snap ring (14), and the second snap ring (14) is movably sleeved with the first snap ring (13).
5. A conveniently eluted SPE column packed with a strongly acidic cation according to claim 4, wherein: the first snap ring (13) is provided with an elastic sheet (15), and a through hole (16) with a trapezoidal cross section is arranged in the second snap ring (14).
6. A strongly acidic cation packed SPE column convenient for elution as claimed in claim 1 wherein: the positioning ring (7) is formed by combining two metal semi-rings.
7. A strongly acidic cation packed SPE column convenient for elution as claimed in claim 1 wherein: the column body (1) comprises an upper column body (17) and a lower column body (20), the upper column body (17) is in threaded connection with the lower column body (20), the lower column body (20) is provided with edges, the lower column body (20) is movably connected with packing plates (18) through the edges, and the packing plates (18) are strong-acid cation packing plates.
8. A conveniently eluted SPE column packed with a strongly acidic cation according to claim 7, wherein: the elution pipe (2) is arranged at the bottom end of the packing plate (18).
9. A strongly acidic cation packed SPE column convenient for elution as claimed in claim 1 wherein: the cylinder (1) is equipped with liquid outlet (19), the diameter of liquid outlet (19) is less than cylinder (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021789478.4U CN215310357U (en) | 2020-08-25 | 2020-08-25 | Strong acid cation filler SPE post convenient to elute |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021789478.4U CN215310357U (en) | 2020-08-25 | 2020-08-25 | Strong acid cation filler SPE post convenient to elute |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215310357U true CN215310357U (en) | 2021-12-28 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202021789478.4U Active CN215310357U (en) | 2020-08-25 | 2020-08-25 | Strong acid cation filler SPE post convenient to elute |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN215310357U (en) |
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2020
- 2020-08-25 CN CN202021789478.4U patent/CN215310357U/en active Active
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