CN215276992U - Experimental device for exosome - Google Patents

Abstract

The utility model relates to the field of biotechnology, in particular to an experimental device for exosome, which comprises a main body, wherein an oscillating seat is movably arranged on the main body, a sliding table is slidably arranged on the oscillating seat, a socket and a chute are arranged on the sliding table, a spring is fixedly arranged in the chute, a positioning block is fixedly connected on the spring, a chute is arranged on the positioning block, a pressing piece is movably arranged on the sliding table, a hanging lug is inserted in the socket, a clamping groove is arranged on the hanging lug, an assembly fixture is fixedly arranged on the hanging lug, and a cushion layer is fixedly arranged on the assembly fixture; through the installation basis of slip table as fixture on the vibration seat, and anchor clamps are components of a whole that can function independently assembled structure, are provided with multiple model, have different curvatures, and the assembly jig of different models is provided with the same hangers, carries out the chooseing for use of assembly jig according to the size of container, and the effectual container of avoiding when causing the oscillation because of unmatching of anchor clamps and container is impaired.

Description

Experimental device for exosome

Technical Field

The utility model relates to the field of biotechnology, specifically be an experimental apparatus for exosome.

Background

Exosomes refer to small membrane vesicles (30-150nm) containing complex RNA and proteins, which today refer to disc-like vesicles 40-100nm in diameter, are secreted by all cultured cell types, and are naturally present in body fluids, including blood, saliva, urine, cerebrospinal fluid, and milk.

In the process of exosome separation extraction and cultivation, detection, often need to vibrate exosome and culture solution and mix, now mostly adorn exosome in the container to use oscillation device to carry out automatic oscillation, but the container anchor clamps that use on present oscillation experimental apparatus are mostly single model number general type, and the range of application is limited, and when the cylinder type container of fixed different external diameters, still leave the gap easily, cause the uneven production of container atress to break. In view of this, we propose an experimental apparatus for exosomes.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide an experimental apparatus for exosome to solve the problem that proposes in the above-mentioned background art.

In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides an experimental apparatus for exosome, includes the main part, movable mounting has the vibration seat in the main part, and slidable mounting has the slip table on the vibration seat, be provided with socket and spout on the slip table, and fixed mounting has the spring in the spout, fixedly connected with locating piece on the spring, and be provided with the chute on the locating piece, movable mounting has the casting die on the slip table, and has pegged graft in the socket, be provided with the draw-in groove on the hangers, and fixed mounting has assembly jig on the hangers, last fixed mounting of assembly jig has the bed course.

Preferably, the main part is oscillator base structure, and the vibration seat is connected at the upper surface of main part, is connected with the drive structure in the vibration seat, the slip table sets up the upper surface at the vibration seat, and the slip table passes through the vice drive of lead screw.

Preferably, the socket is vertical to be set up on the slip table, and spout and socket intercommunication, locating piece slidable mounting is in the spout, and the chute setting is at the upper surface of locating piece, the casting die is installed in the spacing groove at spout top, and the bottom of casting die is arranged in the chute.

Preferably, the clamping grooves are formed in the side faces of the hanging lugs, the assembling fixtures are arc-shaped plates and are provided with 4-8 types of different curvatures, the same hanging lugs are arranged on the assembling fixtures of different types, and the cushion layers are bonded on the surfaces of the assembling fixtures.

Compared with the prior art, the beneficial effects of the utility model are that:

1. the main body is used for installing and driving the oscillating seat, the sliding table is used as an installing base of the clamping mechanism on the oscillating seat, the clamp installed on the sliding table is of a split assembly type structure and is provided with multiple types and different curvatures, the assembling clamps of different types are provided with the same hanging lugs, the fixing with the sliding table can be rapidly completed, before the use, the assembling clamps are selected according to the size of the container, the sliding table type oscillating clamp is suitable for containers of different specifications, and the damage of the container during oscillation caused by the fact that the clamp is not matched with the container is effectively avoided;

2. the utility model provides an assembly jig adopts hangers and slip table to install fast to when needs carry out the change of different model assembly jig, through pushing down the casting die, make the locating piece return and contract in the spout, break away from with the hangers, can extract the hangers, with the dismantlement of accomplishing prototype number assembly jig, it is very convenient to use.

Drawings

Fig. 1 is a front view of the structure of the present invention;

fig. 2 is an enlarged schematic view of the area a in fig. 1.

In the figure: the vibration table comprises a main body 1, a vibration seat 2, a sliding table 3, a socket 4, a sliding groove 5, a spring 6, a positioning block 7, a chute 8, a pressing piece 9, a hanging lug 10, a clamping groove 11, an assembly fixture 12 and a cushion layer 13.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1 to 2, the present invention provides a technical solution: the utility model provides an experimental apparatus for exosome, including main part 1, movable mounting has vibration seat 2 in the main part 1, and slidable mounting has slip table 3 on vibration seat 2, be provided with socket 4 and spout 5 on the slip table 3, and fixed mounting has spring 6 in the spout 5, fixedly connected with locating piece 7 on the spring 6, and be provided with chute 8 on the locating piece 7, movable mounting has casting die 9 on the slip table 3, and the grafting has hangers 10 in the socket 4, be provided with draw-in groove 11 on the hangers 10, and fixed mounting has assembly jig 12 on the hangers 10, fixed mounting has bed course 13 on the assembly jig 12.

The main body 1 is an oscillator base structure, the oscillation base 2 is connected to the upper surface of the main body 1 and is connected with a driving structure in the oscillation base 2, the sliding table 3 is arranged on the upper surface of the oscillation base 2, the sliding table 3 is driven through a screw rod pair, the main body 1 is used for installing and driving the oscillation base 2, and the sliding table 3 is used as an installing base of a clamping mechanism on the oscillation base 2 to clamp and fix an exosome container;

the socket 4 is vertically arranged on the sliding table 3, the sliding groove 5 is communicated with the socket 4, the positioning block 7 is slidably arranged in the sliding groove 5, the chute 8 is arranged on the upper surface of the positioning block 7, the pressing piece 9 is arranged in a limiting groove at the top of the sliding groove 5, the bottom end of the pressing piece 9 is positioned in the chute 8, the socket 4 forms a connecting structure on the sliding table 3, the sliding groove 5 is provided with a fixing structure on the side surface thereof, the positioning block 7 can be popped out of the sliding groove 5 through the elastic force of the spring 6 acting on the positioning block 7, the positioning block 7 is matched with the clamping groove 11 to fix the hanging lug 10, and the pressing piece 9 is pressed downwards, so that the bottom of the pressing piece 9 pushes the positioning block 7 along the chute 8, the positioning block 7 retracts into the sliding groove 5 and is separated from the hanging lug 10;

the clamp groove 11 is arranged on the side face of the hanging lug 10, the assembling clamp 12 is an arc-shaped plate and is provided with 4-8 types and has different curvatures, the assembling clamps 12 of different types are provided with the same hanging lug 10, the cushion layer 13 is bonded on the surface of the assembling clamp 12, before the exosome container is fixed, the assembling clamp 12 can be selected according to the size of the container and is connected through the hanging lug 10, the assembling clamp 12 is installed on the sliding table 3, and the cushion layer 13 can enable the assembling clamp 12 to have a flexible clamping face so as to prevent the container from being damaged;

the working principle is as follows: firstly, the oscillating base 2 is installed and driven through the main body 1, the sliding table 3 is used as an installation base of a clamping mechanism on the oscillating base 2 to clamp and fix an exosome container, before the exosome container is fixed, an assembling clamp 12 can be selected according to the size of the container and is connected through a hanging lug 10, the hanging lug 10 is inserted into a socket 4 and acts on the positioning block 7 through the elastic force of a spring 6, the positioning block 7 can be popped out from the sliding groove 5 and is matched with a clamping groove 11 to fix the hanging lug 10, the assembling clamp 12 is quickly installed on the sliding table 3, the cushion layer 13 can enable the assembling clamp 12 to have a flexible clamping surface to prevent the container from being damaged, when the assembling clamps 12 of different models need to be replaced, the pressing piece 9 is pressed downwards, so that the bottom of the pressing piece 9 pushes the positioning block 7 along the sliding groove 8, so that the positioning block 7 is retracted in the sliding groove 5 and separated from the hanging lug 10, and the hanging lug 10 can be pulled out, thereby completing the disassembly of the original model number assembling clamp 12 and replacing the original model number assembling clamp 12 with a new assembling clamp 12 with a matched model number.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (4)

1. An experimental device for exosomes, comprising a main body (1), characterized in that: movable mounting has vibration seat (2) in main part (1), and slidable mounting has slip table (3) on vibration seat (2), be provided with socket (4) and spout (5) on slip table (3), and fixed mounting has spring (6) in spout (5), fixedly connected with locating piece (7) on spring (6), and be provided with chute (8) on locating piece (7), movable mounting has casting die (9) on slip table (3), and has pegged graft in socket (4), be provided with draw-in groove (11) on hangers (10), and fixed mounting has assembly jig (12) on hangers (10), fixed mounting has bed course (13) on assembly jig (12).

2. An experimental apparatus for exosomes according to claim 1, characterized in that: main part (1) is oscillator base structure, and vibrates the upper surface of seat (2) and connect in main part (1), is connected with the drive structure in vibration seat (2), slip table (3) set up the upper surface at vibration seat (2), and slip table (3) pass through the vice drive of lead screw.

3. An experimental apparatus for exosomes according to claim 1, characterized in that: socket (4) vertical setting is on slip table (3), and spout (5) and socket (4) intercommunication, locating piece (7) slidable mounting is in spout (5), and chute (8) set up the upper surface at locating piece (7), casting die (9) are installed in the spacing groove at spout (5) top, and the bottom of casting die (9) is located chute (8).

4. An experimental apparatus for exosomes according to claim 1, characterized in that: the clamping grooves (11) are formed in the side faces of the hanging lugs (10), the assembling fixtures (12) are arc-shaped plates and are provided with 4-8 types of models and have different curvatures, the assembling fixtures (12) of the different models are provided with the same hanging lugs (10), and the cushion layers (13) are bonded on the surfaces of the assembling fixtures (12).

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