CN215218235U

CN215218235U - Paper scrap ware that punches before scraps of paper blood pretreatment

Info

Publication number: CN215218235U
Application number: CN202023259468.2U
Authority: CN
Inventors: 李松; 王煜; 刘洪娜; 潘文京
Original assignee: Nanjing Arix Biotechnology Co ltd
Current assignee: Nanjing Arix Biotechnology Co ltd
Priority date: 2020-12-29
Filing date: 2020-12-29
Publication date: 2021-12-17
Anticipated expiration: 2030-12-29

Abstract

The utility model provides a wastepaper shredder that punches before scraps of paper blood pretreatment, including handheld portion, conical barrel, ring, handheld portion is hollow structure, the fixed top that sets up at the conical barrel of handheld portion, the fixed bottom that sets up at the conical barrel of ring, the activity of inboard bottom of ring is provided with the blade, the utility model discloses whole body is stainless steel manufacturing, can be used for the disinfection of disinfecting at any time, for broken scraps of paper blood originally provides a novel wastepaper shredder that punches before scraps of paper blood pretreatment, overcomes the above-mentioned problem that exists among the prior art, and provides a simple structure ingenious, can be fully broken with scraps of paper blood, can directly change over to the novel portable wastepaper shredder that punches in the used centrifuging tube of follow-up experiment again.

Description

Paper scrap ware that punches before scraps of paper blood pretreatment

Technical Field

The utility model relates to the technical field of biology, especially, relate to a scraps of paper blood pretreatment paper shredder that punches.

Background

With the continuous improvement of the scientific and technical level and the increasing maturity of the fields of bioscience, clinical medicine, biomedical engineering and the like, the medical health problems which are always concerned by people are greatly improved. The individual information of the patient is acquired from the molecular level by using advanced diagnosis technology, and the information is used for disease prevention, diagnosis and treatment, so that accurate medical treatment is realized. The implementation of individualized medical treatment can greatly improve the health level of human beings, thereby becoming the direction of medical development of the new century.

Nucleic acids are an important component of all known life forms, and the changes experienced by the human body, whether normal physiological processes from birth to aging or pathophysiological processes, are the result of gene expression. Therefore, nucleic acid detection is of great importance for early diagnosis, treatment and prognosis of diseases. The isolation and purification of nucleic acids is the first step in molecular diagnostics, since normal physiological changes and pathological processes are caused by the expression of proteins encoded by mRNA, and mRNA plays an important role in nucleic acid extraction and detection. mRNA samples are not easily stored and need to be stored and transported in a low temperature environment prior to processing. When blood sampling is performed through veins, a detected person needs to go to a designated medical institution, and operation is performed through a specially trained blood sampling person. If the tested person has infectious disease even in low temperature environment with virus carried in blood, the above complicated steps will increase the testing cost.

Therefore, researchers have proposed an alternative method for venous Blood detection, the Dry Blood Spot (DBS) method, also known as the paper strip method. The dry blood spot method is a minimally invasive blood sampling method, and only a small amount of blood at the root of a capillary vessel or finger is collected and dripped on a special paper sheet, and then the special paper sheet and a drying agent are put into a sealing bag together for storage, so that the obtained dry paper sheet blood is a sample to be detected. Blood components are adsorbed on the paper sheet, so that the paper sheet can be stored at normal temperature for a long time, nucleic acid cannot be degraded, the stability is good, and the risk of blood infection in the detection process is reduced. The method can finish the storage and transportation of blood at normal temperature only by using paper sheets, drying agents and sealing bags, and is particularly suitable for areas with poor medical resources. A great deal of literature research shows that DBS has better preservation effect on DNA and RNA, and is widely used for biological detection, such as disease screening.

As a trace nucleic acid sample, a paper blood sample is broken and immersed in a solution, RNA is dissolved from the paper, and then a subsequent extraction experiment is carried out. At present, when a paper sample is broken in a laboratory, the paper sample is directly cut off along the edge by using scissors and then broken, or a paper blood round point is cut off by using a puncher and then broken. Both of the two methods for breaking the paper blood are complicated and inconvenient to store after breaking, greatly increase the possibility of pollution and are not suitable for large-scale and automatic treatment. The invention provides a punching cutter, which solves some defects of the traditional paper scrap crushing, but still does not bring convenience and no pollution to the utmost, so that the invention specially discloses a punching paper scrap crusher for paper scrap blood pretreatment, which can push the cut and crushed paper scrap blood into a subsequently used 1.5ml centrifugal tube in one step and directly be used for treating downstream samples.

SUMMERY OF THE UTILITY MODEL

The utility model aims at solving the shortcoming that exists among the prior art, and the one that proposes can dismantle, can wash, can carry out the broken, avoided the scraps of paper blood pretreatment of sample pollution that processing tool brought in the past to punch the paper shredder according to the required broken size of scraps of paper blood.

In order to achieve the above purpose, the utility model adopts the following technical scheme:

the design is a paper shredder for paper scrap blood pretreatment, and comprises a handheld part, a conical barrel and a circular ring, wherein the handheld part is of a hollow structure, the handheld part is fixedly arranged at the top of the conical barrel, the circular ring is fixedly arranged at the bottom of the conical barrel, and a blade is movably arranged at the bottom of the inner side of the circular ring.

Preferably, the blade is of a net structure, and the edge of the blade is in threaded connection with the circular ring.

Preferably, the inner diameter of the hand-held part is the same as the outer diameter of the mouth of the suction bulb.

Preferably, the blade has a 3 × 3 or 4 × 4 gauge.

Preferably, the handheld part, the circular ring and the conical barrel are of an integrally formed structure.

Preferably, the hand-held part, the circular ring and the conical barrel are made of stainless steel.

Preferably, the inner diameter of the lower part of the circular ring is the same as the size of the inner diameter of the opening of a centrifugal tube of 1.5 ml.

The utility model provides a pair of scraps of paper ware that punches before blood pretreatment, beneficial effect lies in: the utility model aims to automatically extract trace mRNA, provide a novel scraps of paper blood pretreatment paper shredder that punches for broken scraps of paper blood specimen, overcome the above-mentioned problem that exists among the prior art, and provide a simple structure ingenious, simple structure, convenient and fast's such novel scraps of paper blood pretreatment paper shredder.

1. The utility model discloses can carry out the breakage according to the required broken size of scraps of paper blood.

2. The broken paper scraps can be directly blown into a 1.5ml centrifugal tube used in a subsequent experiment, the operation of transferring the paper scraps into the tube is omitted, and the sample pollution caused by the conventional processing tool is avoided.

3. Can be disassembled and cleaned. Such novel scraps of paper blood pretreatment paper shredder that punches has overcome a great deal of not enough that exists in the former experimentation, simple structure, convenient and fast, labour saving and time saving and the pollution problem in the preliminary treatment of experiment that has significantly reduced.

Drawings

Fig. 1 is a schematic structural diagram of the present invention;

fig. 2 is a schematic view of a blade structure according to the present invention;

fig. 3 is a diagram of the cutting effect provided by the present invention.

In the figure: the hand-held part 1, the conical barrel 2, the circular ring 3 and the blade 4.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.

Referring to fig. 1-3, the utility model provides a punching shredder for the pretreatment of paper scrap blood, which comprises a hand-held part 1, a conical barrel 2, a circular ring 3 and a hand-held part 1, ring 3 is the integrated into one piece structure with conical barrel 2, handheld portion 1, ring 3 makes for the stainless steel with conical barrel 2, convenient production, it maintains to be convenient for wash, handheld portion 1 is hollow structure, 1 fixed top that sets up at conical barrel 2 of handheld portion, the internal diameter of handheld portion 1 is the same with the external diameter size of auris suction bulb nib portion, be convenient for blow in the centrifuging tube with the scraps of paper after the cutting, ring 3 is fixed to be set up in conical barrel 2's bottom, ring 3's inboard bottom activity is provided with blade 4, blade 4's specification is 3 x 3 or 4 x 4, blade 4 is network structure, blade 4's edge and ring 3 threaded connection, ring 3's lower part internal diameter is the same with 1.5 ml's centrifuging tube opening internal diameter size.

The working process is as follows: A3X 3-sized blade is arranged on a hollow handle, and the punching paper shredder is wiped clean by alcohol. A clean cutting map was prepared, and the sheet of blood was placed thereon, pressed against the sheet of blood with a punch shredder, and the sheet of blood was broken into 9 pieces and adhered to a net-like blade. A1.5 ml centrifuge tube is aligned with the lower opening of the paper shredder, an ear-sucking ball is aligned with the upper opening of the hollow handle for blowing, and the paper sheets in the grid are blown into the centrifuge tube.

A4 x 4-sized blade is mounted on a hollow handle, and the hole-punching paper shredder is wiped clean with alcohol. A clean cutting map was prepared, and the sheet of blood was placed thereon, pressed against the sheet of blood with a punch shredder, and broken into 16 pieces and adhered to a net-like blade. A1.5 ml centrifuge tube is aligned with the lower opening of the paper shredder, an ear-sucking ball is aligned with the upper opening of the hollow handle for blowing, and the paper sheets in the grid are blown into the centrifuge tube.

The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.

Claims

1. The utility model provides a scraps of paper blood pretreatment shredder that punches, includes handheld portion (1), conical barrel (2), ring (3), its characterized in that: the handheld part (1) is of a hollow structure, the handheld part (1) is fixedly arranged at the top of the conical barrel (2), the circular ring (3) is fixedly arranged at the bottom of the conical barrel (2), and the bottom of the inner side of the circular ring (3) is movably provided with the blade (4).

2. The punching shredder for the pretreatment of paper scraps and blood according to claim 1, wherein: the blade (4) is of a net structure, and the edge of the blade (4) is in threaded connection with the circular ring (3).

3. The punching shredder for the pretreatment of paper scraps and blood according to claim 1, wherein: the inner diameter of the handheld part (1) is the same as the outer diameter of the mouth part of the auricle.

4. The punching shredder for the pretreatment of paper scraps and blood according to claim 1, wherein: the blade (4) has a specification of 3 × 3 or 4 × 4.

5. The punching shredder for the pretreatment of paper scraps and blood according to claim 1, wherein: the handheld part (1), the circular ring (3) and the conical barrel (2) are of an integrally formed structure.

6. The punching shredder for the pretreatment of paper scraps and blood according to claim 1, wherein: the handheld part (1), the circular ring (3) and the conical barrel (2) are made of stainless steel.

7. The punching shredder for the pretreatment of paper scraps and blood according to claim 1, wherein: the inner diameter of the lower part of the circular ring (3) is the same as the size of the inner diameter of the opening of a centrifugal tube of 1.5 ml.