CN215162821U - Adjustable cell model external irradiation device - Google Patents
Adjustable cell model external irradiation device Download PDFInfo
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- CN215162821U CN215162821U CN202121505289.4U CN202121505289U CN215162821U CN 215162821 U CN215162821 U CN 215162821U CN 202121505289 U CN202121505289 U CN 202121505289U CN 215162821 U CN215162821 U CN 215162821U
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Abstract
The utility model relates to a cell model radiation damage irradiation device, which provides an adjustable cell model external irradiation device, comprising a horizontally arranged bottom plate, a plurality of cover plates arranged above the bottom plate, a first through hole arranged on the cover plates, a plurality of baffle plates which are parallel and attached on the cover plates, and a driving device used for driving the baffle plates to rotate; the bottom plate is used for placing a culture dish; the first through hole is arranged right above the culture dish; the cover plate is used for shielding the culture dish; the baffle is provided with a second through hole, and one baffle is provided with a rotating shaft; the rotating shaft is rotatably connected with the cover plate; the diameter of the second through hole is smaller than that of the first through hole; the second through hole is matched with the first through hole. The utility model discloses an irradiation apparatus outside cell model with adjustable can effectively and conveniently adjust the radiation area of cell in the culture dish.
Description
Technical Field
The utility model relates to a cell model radiation damage irradiation apparatus's technical field particularly, relates to a cell model outer irradiation apparatus with adjustable.
Background
Tumor radiotherapy is a local treatment for tumors using radiation. The radiation includes alpha, beta and gamma rays generated by radioactive isotopes, and x-rays, electron beams, proton beams and other particle beams generated by various x-ray therapeutic machines or accelerators. About 70% of cancer patients require radiation therapy in the course of cancer treatment, and about 40% of cancers can be cured by radiation therapy. The role and position of radiotherapy in tumor treatment are increasingly prominent, and the radiotherapy has become one of the main means for treating malignant tumors.
In clinical studies, the response of human cells to radiation and the feasible methods for dealing with radiation, drugs, etc. are often studied by studying the changes of cells in vitro after irradiation and the influence of different drugs on the irradiated cells. For a specific research process, sometimes radiation is required to irradiate a part of cells in a culture dish, and an irradiation hole is usually formed on a cover plate, but the aperture of the irradiation hole is not convenient to adjust. When the influence of irradiation of different areas on cells needs to be studied, the cover plate is usually directly replaced, and batch irradiation is tedious.
In conclusion, the device capable of conveniently adjusting the cell irradiation area in the culture dish is designed to improve the working efficiency to a certain extent.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide an adjustable cell model shines device outward, it can effectively and conveniently adjust the radiation area of cell in the culture dish.
The embodiment of the utility model discloses a realize through following technical scheme: the adjustable cell model external irradiation device comprises a horizontally arranged bottom plate, a plurality of cover plates arranged above the bottom plate, a first through hole arranged on the cover plates, a plurality of baffle plates which are parallel and attached to the cover plates, and a driving device used for driving the baffle plates to rotate; the bottom plate is used for placing a culture dish; the first through hole is arranged right above the culture dish; the cover plate is used for shielding the culture dish; the baffle is provided with a second through hole, and one baffle is provided with a rotating shaft; the rotating shaft is rotatably connected with the cover plate; the diameter of the second through hole is smaller than that of the first through hole; the second through hole is matched with the first through hole.
Further, a baffle plate is provided with a plurality of second through holes, and the diameters of the second through holes are different from each other; the centers of the circles of the plurality of second through holes are all positioned on a circle with the rotating shaft as the center of the circle; the circle center of the first through hole is positioned on the circumference taking the rotating shaft as the circle center.
Furthermore, a support column which is vertically arranged is arranged in the center of the upper surface of the bottom plate; one corner of the lower surface of the cover plate is provided with an inserted rod which is obliquely arranged; a plurality of jacks which are obliquely arranged are arranged on the side wall of the supporting column; and the inserting rod is inserted into the inserting hole.
Furthermore, the cross sections of the inserted rod and the inserted hole are both polygonal; the inserted bar is matched with the insertion hole.
Further, the driving device comprises a driven gear arranged on the side wall of the baffle plate and a driving gear meshed with a plurality of pieces of the driven gear simultaneously.
Furthermore, the driving device also comprises a driving shaft which is vertically arranged and is rotationally connected with the upper end of the supporting column; the driving gear is fixedly connected with the driving shaft.
Further, the driving device also comprises a knob arranged at the end part of one end of the driving shaft far away from the supporting column.
Furthermore, a plurality of limiting rings are fixedly arranged on the upper surface of the bottom plate, and one limiting ring is used for accommodating one culture dish.
Further, the cover plate and the baffle are made of lead materials.
Furthermore, the cover plate is provided with 4 pieces, and the 4 pieces of cover plate are arranged in a matrix.
The technical scheme of the utility model following beneficial effect has at least: the utility model discloses an adjustable cell model shines device outward, place the culture dish on the bottom plate, and make the culture dish be in under first through-hole, when using the ray of radiation source directly over the bottom plate to shine the cell in the culture dish, the apron can block the ray, make it only pass through first through-hole, and then only shine the part cell under the first through-hole, when the area is shone in needs reducing, can use drive arrangement rotating baffle, make the second through-hole on the baffle shelter from first through-hole, because the diameter of second through-hole is less than first through-hole, consequently just adjusted the area of shone. When need not shine the cell in the culture dish completely, make the baffle shelter from first through-hole completely can, when need shine the cell in the whole culture dish, directly with the apron take off can, can guarantee this moment that a plurality of culture dishes are in same height, receive the radiation of same condition. Therefore, the device is not only simple to operate, but also applicable to a plurality of scenes, simple to manufacture, and very high in cost and reliability.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention, and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
FIG. 1 is a schematic structural diagram of an adjustable external irradiation device for cell model according to an embodiment of the present invention;
FIG. 2 is a schematic structural diagram of a bottom plate portion of an adjustable cell model external irradiation device according to an embodiment of the present invention;
FIG. 3 is a schematic structural diagram of a baffle portion of an adjustable cell model external irradiation device according to an embodiment of the present invention;
fig. 4 is a schematic structural diagram of a cover plate portion of an adjustable cell model external irradiation device according to an embodiment of the present invention.
Icon: 10-bottom plate, 11-limiting ring, 12-supporting column, 13-jack, 14-driving rod, 15-driving gear, 16-knob, 20-cover plate, 21-first through hole, 22-inserted rod, 30-baffle, 31-second through hole, 32-driven gear, 33-rotating shaft and 40-culture dish.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention, as generally described and illustrated in the figures herein, may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the accompanying drawings, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.
In the description of the present invention, it should be noted that, if the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, or the orientation or positional relationship which is usually placed when the product of this application is used, the description is only for convenience of description and simplification, but the indication or suggestion that the device or element to be referred must have a specific orientation, be constructed in a specific orientation and be operated is not to be construed as limiting the present invention.
In the description of the present invention, it should be further noted that unless otherwise explicitly stated or limited, the terms "disposed," "mounted," "connected," and "connected" should be interpreted broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Examples
As shown in FIGS. 1-4, the adjustable cell model external irradiation device of the present embodiment comprises a horizontally disposed bottom plate 10, a plurality of cover plates 20 disposed above the bottom plate 10, a first through hole 21 formed in the cover plate 20, a plurality of parallel baffles 30 attached to the cover plate 20, and a driving device for driving the plurality of baffles 30 to rotate; the bottom plate 10 is used for placing a culture dish 40; a first through hole 21 is arranged right above a culture dish 40; the cover plate 20 is used for shielding the culture dish 40; the baffle 30 is provided with a second through hole 31, and a rotating shaft 33 is arranged on one baffle 30; a rotating shaft 33 is rotatably connected with a cover plate 20; the diameter of the second through hole 31 is smaller than the diameter of the first through hole 21; the second through hole 31 matches the first through hole 21. Specifically, the culture dish 40 is placed on the bottom plate 10, the culture dish 40 is located under the first through hole 21, when the radiation source irradiates cells in the culture dish 40 through the radiation above the bottom plate 10, the cover plate 20 can block the radiation, so that the radiation only passes through the first through hole 21 and further only irradiates partial cells under the first through hole 21, when the irradiation area needs to be reduced, the baffle plate 30 can be rotated by using the driving device, so that the second through hole 31 on the baffle plate 30 shields the first through hole 21, and the irradiation area is reduced because the diameter of the second through hole 31 is smaller than that of the first through hole 21. When the cells in the culture dish 40 need not to be irradiated completely, the baffle 30 can completely shield the first through hole 21, when the cells in the whole culture dish 40 need to be irradiated, the cover plate 20 can be directly taken down, and at the moment, the plurality of culture dishes 40 can be ensured to be at the same height and be irradiated under the same conditions. Therefore, the device is not only simple to operate, but also applicable to a plurality of scenes, simple to manufacture, and very high in cost and reliability.
A baffle 30 in this embodiment is provided with a plurality of second through holes 31, and the diameters of the plurality of second through holes 31 are different from each other; the centers of the circles of the second through holes 31 are all positioned on the circumference taking the rotating shaft 33 as the center of the circle; the center of the first through hole 21 is located on a circle with the rotating shaft 33 as the center. Specifically, providing a plurality of second through holes 31 of different diameters makes it possible to adjust the irradiation area over a wider range. When in use, the baffle 30 is rotated by the driving device, so that the first through hole 21 is shielded by the second through holes 31 with different diameters.
A support column 12 which is vertically arranged is arranged in the center of the upper surface of the bottom plate 10 in the embodiment; an inserting rod 22 which is obliquely arranged is arranged at one corner of the lower surface of the cover plate 20; the side wall of the support column 12 is provided with a plurality of obliquely arranged jacks 13; an insert rod 22 is inserted into an insert hole 13. Specifically, when the cover plate 20 is mounted, the insertion rod 22 on the lower surface of the cover plate 20 is inserted into the insertion hole 13. The disassembly and the assembly are very convenient.
The cross sections of the insertion rod 22 and the insertion hole 13 in the embodiment are both polygonal; the insertion rod 22 is matched with the insertion hole 13. Specifically, the polygonal insertion rod 22 and the insertion hole 13 can prevent the insertion rod 22 from shaking after being inserted into the insertion hole 13, so that the cover plate 20 is fixed more stably.
The driving means in this embodiment includes a driven gear 32 provided on a side wall of the barrier 30, and a driving gear 15 engaged with a plurality of pieces of the driven gear 32 at the same time. The driving device also comprises a driving shaft which is vertically arranged and is rotationally connected with the upper end of the supporting column 12; the driving gear 15 is fixedly connected with the driving shaft. Specifically, the driving gear 15 can be rotated by rotating the driving shaft on the supporting column 12, and then the driven gears 32 are driven to rotate at the same time, so that the purpose of adjusting the irradiation areas of the culture dishes 40 at the same time is realized. In addition, when the irradiation area of each culture dish 40 needs to be adjusted individually, only the corresponding cover plate 20 needs to be removed, and then the driven gear 32 needs to be manually shifted.
The drive means in this embodiment further comprises a knob 16 at the end of the drive shaft remote from the support post 12.
In this embodiment, a plurality of retaining rings 11 are fixed on the upper surface of the bottom plate 10, and one retaining ring 11 is used to accommodate one culture dish 40. Specifically, the stop collar 11 can define the placement position of the culture dish 40, and can accurately place the culture dish 40 right below the first through hole 21 each time.
The cover plate 20 and the baffle 30 in this embodiment are made of lead material. Specifically, the lead material can effectively block radiation such as X-rays.
The cover plate 20 in this embodiment is provided with 4 pieces, and the 4 pieces of the cover plate 20 are arranged in a matrix. In particular, the size of the radiation source is limited to avoid too many culture dishes 40 causing different radiation to each culture dish 40, and too large an inclination angle of the culture dishes 40 to the radiation source causes the radiation area to be distorted. Only 4 culture dishes 40 and 4 cover plates 20 are therefore provided.
In summary, in the adjustable cell model external irradiation device of the embodiment, the culture dish 40 is placed on the bottom plate 10, and the culture dish 40 is located right below the first through hole 21, when the radiation source irradiates the cells in the culture dish 40 with the radiation right above the bottom plate 10, the cover plate 20 can block the radiation, so that the radiation only passes through the first through hole 21, and further only irradiates the partial cells right below the first through hole 21, when the irradiation area needs to be reduced, the driving device can be used to rotate the baffle plate 30, so that the second through hole 31 on the baffle plate 30 blocks the first through hole 21, and since the diameter of the second through hole 31 is smaller than that of the first through hole 21, the irradiation area is reduced. When the cells in the culture dish 40 need not to be irradiated completely, the baffle 30 can completely shield the first through hole 21, when the cells in the whole culture dish 40 need to be irradiated, the cover plate 20 can be directly taken down, and at the moment, the plurality of culture dishes 40 can be ensured to be at the same height and be irradiated under the same conditions. Therefore, the device is not only simple to operate, but also applicable to a plurality of scenes, simple to manufacture, and very high in cost and reliability.
The above is only a preferred embodiment of the present invention, and is not intended to limit the present invention, and various modifications and changes will occur to those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. An adjustable cell model external irradiation device, characterized in that: the device comprises a horizontally arranged bottom plate, a plurality of cover plates arranged above the bottom plate, a first through hole formed in the cover plates, a plurality of baffle plates which are parallel to each other and are attached to the cover plates, and a driving device used for driving the baffle plates to rotate; the bottom plate is used for placing a culture dish; the first through hole is arranged right above the culture dish; the cover plate is used for shielding the culture dish;
the baffle is provided with a second through hole, and one baffle is provided with a rotating shaft; the rotating shaft is rotatably connected with the cover plate; the diameter of the second through hole is smaller than that of the first through hole; the second through hole is matched with the first through hole.
2. The adjustable extra-cellular model illumination device of claim 1, wherein: a plurality of second through holes are formed in the baffle plate, and the diameters of the second through holes are different from each other; the centers of the circles of the plurality of second through holes are all positioned on a circle with the rotating shaft as the center of the circle; the circle center of the first through hole is positioned on the circumference taking the rotating shaft as the circle center.
3. The adjustable extra-cellular model illumination device of claim 1, wherein: a support pillar which is vertically arranged is arranged in the center of the upper surface of the bottom plate; one corner of the lower surface of the cover plate is provided with an inserted rod which is obliquely arranged; a plurality of jacks which are obliquely arranged are arranged on the side wall of the supporting column; and the inserting rod is inserted into the inserting hole.
4. The adjustable extra-cellular model illumination device of claim 3, wherein: the cross sections of the inserted rod and the jack are polygonal; the inserted bar is matched with the insertion hole.
5. The adjustable extra-cellular model illumination device of claim 3, wherein: the driving device comprises driven gears arranged on the side wall of the baffle plate and driving gears meshed with a plurality of driven gears simultaneously.
6. The adjustable extra-cellular model illumination device of claim 5, wherein: the driving device also comprises a driving shaft which is vertically arranged and is rotationally connected with the upper end of the supporting column; the driving gear is fixedly connected with the driving shaft.
7. The adjustable extra-cellular model illumination device of claim 6, wherein: the driving device further comprises a knob arranged at the end part of one end, far away from the supporting column, of the driving shaft.
8. The adjustable extra-cellular model illumination device of claim 1, wherein: the upper surface of the bottom plate is fixedly provided with a plurality of limiting rings, and one limiting ring is used for accommodating one culture dish.
9. The adjustable extracellular matrix irradiation device of any one of claims 1-8, wherein: the cover plate and the baffle are made of lead materials.
10. The adjustable extra-cellular model illumination device of claim 9, wherein: the cover plate is provided with 4 pieces, and the 4 pieces of cover plate are arranged in a matrix.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121505289.4U CN215162821U (en) | 2021-07-01 | 2021-07-01 | Adjustable cell model external irradiation device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121505289.4U CN215162821U (en) | 2021-07-01 | 2021-07-01 | Adjustable cell model external irradiation device |
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| CN215162821U true CN215162821U (en) | 2021-12-14 |
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| CN202121505289.4U Active CN215162821U (en) | 2021-07-01 | 2021-07-01 | Adjustable cell model external irradiation device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117551549A (en) * | 2024-01-12 | 2024-02-13 | 中国人民解放军总医院海南医院 | Seawater nuclear radiation tumor cell canceration period measurement equipment and method |
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2021
- 2021-07-01 CN CN202121505289.4U patent/CN215162821U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117551549A (en) * | 2024-01-12 | 2024-02-13 | 中国人民解放军总医院海南医院 | Seawater nuclear radiation tumor cell canceration period measurement equipment and method |
| CN117551549B (en) * | 2024-01-12 | 2024-04-05 | 中国人民解放军总医院海南医院 | Seawater nuclear radiation tumor cell canceration period measurement equipment and method |
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