CN215140009U - Low-cost digital micro-fluidic system - Google Patents
Low-cost digital micro-fluidic system Download PDFInfo
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- CN215140009U CN215140009U CN202120373565.XU CN202120373565U CN215140009U CN 215140009 U CN215140009 U CN 215140009U CN 202120373565 U CN202120373565 U CN 202120373565U CN 215140009 U CN215140009 U CN 215140009U
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Abstract
A low-cost digital microfluidic system comprises a computer, a microcontroller, a relay module, a bread board, a driving circuit module and a digital microfluidic chip; the signal output end of the computer is connected with the signal input end of the microcontroller; the I/O port of the microcontroller is electrically connected with the I/O port of the relay module; the driving circuit module is electrically connected with the controlled end of the relay module through the bread board; the digital microfluidic chip is electrically connected with the controlled end of the relay module; the digital microfluidic chip comprises a substrate, an electrode, a dielectric hydrophobic layer and an adhesive; the substrate is made of a polyester film; the electrode is made of conductive carbon ink; the adhesive is made of acrylic resin; the dielectric hydrophobic layer is made of a BOPP film. The utility model discloses reduce manufacturing cost, improved the use convenience.
Description
Technical Field
The utility model relates to a digital micro-fluidic system, especially a low-cost and handy digital micro-fluidic system belong to micro-fluidic technical field.
Background
Microfluidics refers to the science and technology involved in systems that process or manipulate tiny fluids using microchannels, an emerging interdiscipline that involves chemistry, fluid physics, microelectronics, new materials, biology, and biomedical engineering; the micro-fluidic has unique fluid properties in a micro-scale environment, and micro-machining and micro-operation which cannot be completed by some conventional methods can be realized by the micro-fluidic through the unique fluid phenomena, so that the micro-fluidic has huge development potential and wide application prospect in biomedical research; the digital microfluidic chip is a novel microfluidic branch, metal electrodes are generally processed by adopting methods such as photoetching, sputtering and the like in the process of manufacturing the digital microfluidic chip, substances such as polytetrafluoroethylene, parylene and the like are processed on the surfaces of the electrodes to serve as dielectric layers by a vapor deposition method, Teflon is processed on the surfaces of the dielectric layers to serve as hydrophobic layers by the vapor deposition method, and equipment and materials adopted in the processing processes are extremely expensive, so that the manufacturing cost of the digital microfluidic chip is extremely high; moreover, the movement of the liquid drop in the digital microfluidic chip needs a high-voltage power supply device formed by connecting a function signal generator and a high-voltage amplifier to provide a driving voltage signal for the high-voltage power supply device, and the power supply device has high cost and large volume and is not beneficial to large-scale use of the digital microfluidic chip; therefore, a digital microfluidic system with low cost and simple structure is needed, so as to reduce the production cost.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to overcome prior art's not enough, provide a low-cost digital micro-fluidic system, it not only can reduce digital micro-fluidic system's manufacturing cost, can also simplify its structure.
The problem is solved through following technical scheme:
a low-cost digital microfluidic system comprises a computer, a microcontroller, a relay module, a bread board, a driving circuit module and a digital microfluidic chip; the signal output end of the computer is connected with the signal input end of the microcontroller; the I/O port of the microcontroller is electrically connected with the I/O port of the relay module; the driving circuit module is electrically connected with the controlled end of the relay module through the bread board; the digital microfluidic chip is electrically connected with the controlled end of the relay module; the digital microfluidic chip comprises a substrate, an electrode, a dielectric hydrophobic layer and an adhesive; an electrode is arranged on the upper end face of the base body; the upper end face of the electrode is provided with an adhesive, and the part of the upper end face of the substrate, which is not covered by the electrode, is also provided with the adhesive; a dielectric hydrophobic layer is arranged at the upper end of the adhesive; the substrate is made of a polyester film; the electrode is made of conductive carbon ink; the adhesive is made of acrylic resin; the dielectric hydrophobic layer is made of a BOPP film.
In the low-cost digital microfluidic system, the microcontroller is a 51-singlechip minimum system.
In the low-cost digital microfluidic system, the driving circuit module comprises a battery, a triode, a resistor and a transformer; the positive electrode of the battery is connected with the collector of the triode; the negative electrode of the battery is connected with the emitting electrode of the triode through the first primary coil of the transformer; the base of the triode is connected with one end of a second primary coil of the transformer through a resistor, and the other end of the second primary coil of the transformer is connected with the anode of the battery; and the first primary coil of the transformer and the second primary coil of the transformer are in magnetic coupling connection with the secondary coil of the transformer.
In the low-cost digital microfluidic system, the type of the triode is NECD 822P; the resistance value of the resistor is 1K omega; the battery is a rechargeable lithium battery with the voltage of 3.7V, and the output voltage of the secondary coil of the transformer is 120V alternating current.
In the low-cost digital microfluidic system, the controlled end of the relay module is connected with the electrode through the alligator clamp lead.
The utility model simplifies the drive circuit module, and no expensive equipment such as a function signal generator and a high-voltage amplifier is needed to provide drive voltage for the liquid drop movement, thereby greatly reducing the power cost, increasing the convenience of the use of the digital micro-fluidic system, and avoiding the inconvenience caused by the heavy power supply which is difficult to move in the past; the digital microfluidic chip can be manufactured without expensive equipment and materials, so that the processing cost of the digital microfluidic system is reduced.
Drawings
FIG. 1 is a schematic structural view of the present invention;
fig. 2 is a schematic structural diagram of the digital microfluidic chip of the present invention;
fig. 3 is a schematic structural diagram of the driving circuit module of the present invention;
fig. 4 is a schematic diagram of the structure of the liquid drop moving sequence of the present invention.
The list of labels in the figure is: 1. the system comprises a microcontroller, 2, a relay module, 3, a bread board, 4, a driving circuit module, 4-1, a battery, 4-2, a triode, 4-3, a resistor, 4-4, a transformer, 5, a digital microfluidic chip, 5-1, a substrate, 5-2, an electrode, 5-3, a dielectric hydrophobic layer and 5-4, an adhesive.
Detailed Description
Referring to fig. 1, 2, 3 and 4, the present invention includes a computer, a microcontroller 1, a relay module 2, a bread board 3, a driving circuit module 4 and a digital microfluidic chip 5; the signal output end of the computer is connected with the signal input end of the microcontroller 1; the I/O port of the microcontroller 1 is electrically connected with the I/O port of the relay module 2; the driving circuit module 4 is electrically connected with the controlled end of the relay module 2 through the bread board 3; and the digital micro-fluidic chip 5 is electrically connected with the controlled end of the relay module 2.
The digital microfluidic chip 5 comprises a substrate 5-1, an electrode 5-2, a dielectric hydrophobic layer 5-3 and an adhesive 5-4; an electrode 5-2 is arranged on the upper end face of the substrate 5-1; the upper end face of the electrode 5-2 is provided with an adhesive 5-4, and the part of the upper end face of the substrate 5-1 which is not covered by the electrode 5-2 is also provided with the adhesive 5-4; a dielectric hydrophobic layer 5-3 is arranged at the upper end of the adhesive 5-4; the substrate 5-1 is made of a polyester film; the electrode 5-2 is made of conductive carbon ink; the adhesive 5-4 is made of acrylic resin; the dielectric hydrophobic layer 5-3 is made of a BOPP film; the electrode 5-2 is formed by processing conductive carbon ink on the substrate 5-1 by a screen printing technology; the adhesive 5-4 serves to bond the substrate 5-1 and the dielectric hydrophobic layer 5-3 together, thereby preventing air bubbles from being generated therebetween to affect the movement of the droplets.
The microcontroller 1 is a 51-singlechip minimum system.
The driving circuit module 4 comprises a battery 4-1, a triode 4-2, a resistor 4-3 and a transformer 4-4; the positive electrode of the battery 4-1 is connected with the collector electrode of the triode 4-2; the negative electrode of the battery 4-1 is connected with the emitting electrode of the triode 4-2 through a first primary coil of the transformer 4-4; the base electrode of the triode 4-2 is connected with one end of a second primary coil of the transformer 4-4 through the resistor 4-3, and the other end of the second primary coil of the transformer 4-4 is connected with the positive electrode of the battery 4-1; the first primary coil of the transformer 4-4 and the second primary coil of the transformer 4-4 are in magnetic coupling connection with the secondary coil of the transformer 4-4; the type of the triode 4-2 is NECD 822P; the resistance value of the resistor 4-3 is 1K omega; the battery 4-1 is a rechargeable lithium battery with the voltage of 3.7V, and the output voltage of the secondary coil of the transformer 4-4 is 120V alternating current.
The controlled end of the relay module 2 is connected with the electrode 5-2 through an alligator clip lead.
This neotype digital micro-fluidic chip 5 has adopted a motion time sequence control liquid drop that has middle transition time sequence to move on the plane, merge and move on the curved surface, promptly when the liquid drop is about to move to next group's electrode, make two sets of electrodes all circular telegrams earlier, then, make first group's electrode outage again and make second group's electrode still keep the on-state, thereby make the liquid drop move on second group's electrode, this kind of motion time sequence can make the liquid drop continuous motion on the plane, and can prevent that the liquid drop landing from to the bottom of curved surface when moving on the curved surface, thereby guarantee the liquid drop continuous motion on the curved surface, the reliability of experiment has been improved.
The method comprises the following specific operation steps: writing a program on a computer through Keil software, connecting the computer with the microcontroller 1, and inputting the program into a 51-chip of the microcontroller 1; 51, after receiving a code sent by a computer, the singlechip chip acquires a level signal and a time sequence of a corresponding target electrode according to a target electrode serial number contained in the code; the 51 single chip microcomputer converts the program control parameters into level signals and sends the level signals into the relay module 2 through the I/O port; and the relay module closes the relay corresponding to the target electrode according to the obtained level signal, the driving circuit module, the target electrode and the relay corresponding to the target electrode form a power-on loop at the moment, and the target electrode is powered on to induce the liquid drops to move.
Claims (5)
1. A low-cost digital microfluidic system, characterized in that: the system comprises a computer, a microcontroller (1), a relay module (2), a bread board (3), a driving circuit module (4) and a digital micro-fluidic chip (5); the signal output end of the computer is connected with the signal input end of the microcontroller (1); the I/O port of the microcontroller (1) is electrically connected with the I/O port of the relay module (2); the drive circuit module (4) is electrically connected with the controlled end of the relay module (2) through the bread board (3); the digital micro-fluidic chip (5) is electrically connected with the controlled end of the relay module (2); the digital microfluidic chip (5) comprises a substrate (5-1), an electrode (5-2), a dielectric hydrophobic layer (5-3) and an adhesive (5-4); an electrode (5-2) is arranged on the upper end face of the substrate (5-1); the upper end face of the electrode (5-2) is provided with an adhesive (5-4), and the part of the upper end face of the substrate (5-1) which is not covered by the electrode (5-2) is also provided with the adhesive (5-4); a dielectric hydrophobic layer (5-3) is arranged at the upper end of the adhesive (5-4); the substrate (5-1) is made of a polyester film; the electrode (5-2) is made of conductive carbon ink; the adhesive (5-4) is made of acrylic resin; the dielectric hydrophobic layer (5-3) is made of a BOPP film.
2. The low-cost digital microfluidic system according to claim 1, wherein: the microcontroller (1) is a 51-singlechip minimum system.
3. The low-cost digital microfluidic system according to claim 2, wherein: the driving circuit module (4) comprises a battery (4-1), a triode (4-2), a resistor (4-3) and a transformer (4-4); the positive electrode of the battery (4-1) is connected with the collector electrode of the triode (4-2); the cathode of the battery (4-1) is connected with the emitter of the triode (4-2) through a first primary coil of the transformer (4-4); the base of the triode (4-2) is connected with one end of a second primary coil of the transformer (4-4) through a resistor (4-3), and the other end of the second primary coil of the transformer (4-4) is connected with the anode of the battery (4-1); and the first primary coil of the transformer (4-4) and the second primary coil of the transformer (4-4) are in magnetic coupling connection with the secondary coil of the transformer (4-4).
4. The low-cost digital microfluidic system according to claim 3, wherein: the type of the triode (4-2) is NECD 822P; the resistance value of the resistor (4-3) is 1K omega; the battery (4-1) is a rechargeable lithium battery with the voltage of 3.7V, and the output voltage of the secondary coil of the transformer (4-4) is 120V alternating current.
5. The low-cost digital microfluidic system according to claim 4, wherein: the controlled end of the relay module (2) is connected with the electrode (5-2) through an alligator clip lead.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120373565.XU CN215140009U (en) | 2021-02-08 | 2021-02-08 | Low-cost digital micro-fluidic system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120373565.XU CN215140009U (en) | 2021-02-08 | 2021-02-08 | Low-cost digital micro-fluidic system |
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| Publication Number | Publication Date |
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| CN215140009U true CN215140009U (en) | 2021-12-14 |
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| CN202120373565.XU Expired - Fee Related CN215140009U (en) | 2021-02-08 | 2021-02-08 | Low-cost digital micro-fluidic system |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024032791A1 (en) * | 2022-08-12 | 2024-02-15 | 江苏液滴逻辑生物技术有限公司 | Thin film, digital microfluidic chip substrate and preparation method therefor |
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2021
- 2021-02-08 CN CN202120373565.XU patent/CN215140009U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024032791A1 (en) * | 2022-08-12 | 2024-02-15 | 江苏液滴逻辑生物技术有限公司 | Thin film, digital microfluidic chip substrate and preparation method therefor |
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Granted publication date: 20211214 |
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| CF01 | Termination of patent right due to non-payment of annual fee |