CN215136069U - Photoacoustic power therapeutic instrument - Google Patents

Photoacoustic power therapeutic instrument Download PDF

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Publication number
CN215136069U
CN215136069U CN202120135125.0U CN202120135125U CN215136069U CN 215136069 U CN215136069 U CN 215136069U CN 202120135125 U CN202120135125 U CN 202120135125U CN 215136069 U CN215136069 U CN 215136069U
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acousto
laser
optic
ultrasonic
photoacoustic
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CN202120135125.0U
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陈芸
郑婷婷
孙德胜
李萍
戚玉龙
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SHENZHEN PKU-HKUST MEDICAL CENTER
Peking University Shenzhen Hospital
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SHENZHEN PKU-HKUST MEDICAL CENTER
Peking University Shenzhen Hospital
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Abstract

The utility model belongs to the technical field of medical instrument, concretely relates to optoacoustic power therapeutic instrument. The utility model provides a photoacoustic power therapeutic instrument, includes quick-witted case, its characterized in that: the device also comprises an acousto-optic generating device and a control component; the acousto-optic generating device and the control component are both arranged in the case; the acousto-optic generating device is electrically connected to the control part; the acousto-optic generating device can emit laser or ultrasonic wave independently and can also emit the laser and the ultrasonic wave simultaneously. This application provides a portable equipment that can be used for shallow and deep tissue disease not to have the reputation synchronous treatment of creating simultaneously through combining together photodynamic technique and acoustic power technique, compares prior art, has that convenient operation is simple, the sensitizing agent quantity is few and treatment effect is guaranteed etc. technological effect.

Description

Photoacoustic power therapeutic instrument
Technical Field
The application belongs to the technical field of medical equipment, concretely relates to optoacoustic power therapeutic instrument.
Background
The lasers currently used in photodynamic therapy (PDT) provide light at only one or a few wavelengths and are limited in their functionality due to the limited penetration of the laser light, which is only used to treat superficial lesions. The sonodynamic therapy apparatus for sonodynamic therapy (SDT) can penetrate deep tissues by activating a sensitizer with ultrasonic waves, making up for the deficiency of PDT.
SUMMERY OF THE UTILITY MODEL
In view of this, the present application provides a photoacoustic power therapeutic apparatus to solve the technical problems in the prior art.
The solution adopted by the application to solve the technical problem is as follows:
the utility model provides a photoacoustic power therapeutic instrument, includes quick-witted case, its characterized in that: the device also comprises an acousto-optic generating device and a control component; the acousto-optic generating device and the control component are both arranged in the case; the acousto-optic generating device is electrically connected to the control part; the acousto-optic generating device can emit laser or ultrasonic wave independently and can also emit the laser and the ultrasonic wave simultaneously.
Preferably, the acousto-optic generating device comprises a laser generator, an acousto-optic modulator, an ultrasonic oscillation circuit and an ultrasonic transducer; the laser generator and the ultrasonic oscillation circuit are electrically connected to the control component, the laser generator is used for emitting laser, the acousto-optic modulator is used for adjusting the laser emitted by the laser generator, the ultrasonic oscillation circuit is used for generating ultrasonic oscillation, and the ultrasonic transducer is used for converting the ultrasonic oscillation generated by the ultrasonic oscillation circuit into ultrasonic waves.
Preferably, the acousto-optic generating device comprises a laser generator, an acousto-optic transmission tunnel and an acousto-optic synchronous component; the laser generator is used for emitting laser, the acousto-optic synchronous component is used for forming an annular array laser source and generating ultrasonic waves through the cooperation of the acousto-optic transmission tunnel, and the acousto-optic transmission tunnel is used for transmitting the laser and the ultrasonic waves generated by the acousto-optic synchronous component.
Preferably, the cross section of the acousto-optic transmission tunnel has a perfect circular structure; the acousto-optic synchronous component comprises a cylindrical part and a conical part, and annular grating arrays which are mutually communicated are arranged in the cylindrical part and the conical part; the acousto-optic synchronous component is arranged in the acousto-optic transmission tunnel and is mutually overlapped with the axis of the acousto-optic transmission tunnel, and the conical part of the acousto-optic synchronous component faces the incident end of the laser.
Preferably, the laser generator is a laser diode.
Preferably, the acousto-optic generating device further comprises a laser beam expander, and the laser beam expander is arranged between the laser generator and the acousto-optic synchronous component and used for adjusting the radiation form of the laser beam.
Preferably, the acousto-optic generating device further comprises an acousto-optic modulator for adjusting the intensity and frequency of the concentric ring-shaped laser source formed by the ring-shaped grating array.
Preferably, the acousto-optic generation device can emit one or more of 193-337nm ultraviolet light, 488nm blue light, 514nm green light, 633nm red light, 1064nm near-infrared light and 570-650nm dimmable light.
Preferably, the ultrasonic frequency generated by the acousto-optic generating device is 100kHz to 2 MHz.
Preferably, the photoacoustic dynamic therapy apparatus further comprises a laser intensity adjusting component, a laser frequency adjusting component, an ultrasonic intensity adjusting component and an ultrasonic frequency adjusting component; the laser intensity adjusting component, the laser frequency adjusting component, the ultrasonic intensity adjusting component and the ultrasonic frequency adjusting component are all arranged in and/or on the case; the laser intensity adjusting component, the laser frequency adjusting component, the ultrasonic intensity adjusting component and the ultrasonic frequency adjusting component are all electrically connected to the control component.
Preferably, the photoacoustic dynamic therapy apparatus further comprises a laser display and an ultrasonic display; the laser display and the ultrasonic display are both arranged in and/or on the case; the laser display and the ultrasonic display are both electrically connected to the control part.
Preferably, the photoacoustic dynamic therapy apparatus further comprises a laser waveguide device and an ultrasonic waveguide device; the laser waveguide device and the ultrasonic waveguide device are both arranged in and/or on the case; the laser waveguide device and the ultrasonic waveguide device are both electrically connected to the acousto-optic generating device.
Preferably, the photoacoustic powertreatment apparatus further comprises a photoacoustic wave guide device for transmitting laser and/or ultrasound waves.
The beneficial technical effects are as follows:
1. the present application provides a portable device that can be used for noninvasive treatment of superficial and deep tissue diseases simultaneously by combining photoacoustic power technology. Compared with the prior art, the method has the technical effects of convenient and simple operation, small dosage of the sensitizing agent, guaranteed treatment effect and the like.
2. In the embodiment of the application, the laser generator, the acousto-optic transmission tunnel and the acousto-optic synchronous component are used as the acousto-optic generating device, so that the acousto-optic synchronous device not only can be used for noninvasive acousto-optic synchronous treatment of superficial and deep tissue diseases, but also has the technical effects of uniform energy distribution, good acousto-optic signal synchronization performance, simplicity in operation, convenience in use and the like. Meanwhile, the annular laser source is used as a laser source for acousto-optic synchronous treatment, and the technical effects of high energy efficiency, small side effect on a human body, higher safety performance and the like are achieved.
The technical solutions and technical effects of the present application will be described in detail below with reference to the drawings and the detailed description of the present application.
Drawings
FIG. 1: the structure of the first preferred embodiment is schematically shown;
FIG. 2: the structure of the second preferred embodiment is schematically shown;
FIG. 3: the structure schematic diagram of the acousto-optic generating device;
FIG. 4: the front projection of the acousto-optic synchronous component;
FIG. 5: a side perspective view of the acousto-optic synchronizing member;
and (3) identification and explanation:
10-acousto-optic generation device, 20-laser intensity adjusting component, 30-laser frequency adjusting component, 40-ultrasonic intensity adjusting component, 50-ultrasonic frequency adjusting component, 60-laser display, 70-ultrasonic display, 80-laser waveguide device, 90-ultrasonic waveguide device and 100-photoacoustic waveguide device;
110-laser generator, 120-acousto-optic transmission tunnel, 130-acousto-optic synchronous component;
1310-cylindrical portion, 1320-conical portion, 1330-annular grating array.
Detailed Description
First preferred embodiment
Referring to fig. 1, a photoacoustic power therapeutic apparatus includes a case, in which an acousto-optic generating device 10, a laser intensity adjusting part 20, a laser frequency adjusting part 30, an ultrasonic intensity adjusting part 40, an ultrasonic frequency adjusting part 50, a laser display 60, an ultrasonic display 70, a laser waveguide device 80, an ultrasonic waveguide device 90 and a control part are disposed; the laser intensity adjusting component 20, the laser frequency adjusting component 30, the ultrasonic intensity adjusting component 40, the ultrasonic frequency adjusting component 50, the laser display 60 and the ultrasonic display 70 are all arranged in and/or on the case and are electrically connected to the control component; the laser waveguide device 80 and the ultrasonic waveguide device 90 are both connected to the acousto-optic generating device 10 for receiving and transmitting laser light and/or ultrasonic waves emitted by the acousto-optic generating device 10.
The acousto-optic generating device 10 comprises a laser generator, an acousto-optic modulator, an ultrasonic oscillation circuit and an ultrasonic transducer; the laser generator and the ultrasonic oscillation circuit are electrically connected to the control component. The laser generator is used for emitting laser, the acousto-optic modulator is used for adjusting the laser emitted by the laser generator, the ultrasonic oscillation circuit is used for generating ultrasonic oscillation, and the ultrasonic transducer is used for converting the ultrasonic oscillation generated by the ultrasonic oscillation circuit into ultrasonic waves.
The laser waveguide device 80 and the ultrasonic waveguide device 90 are used for receiving and transmitting laser emitted by the laser generator and ultrasonic waves generated by the ultrasonic transducer, respectively. Various waveguide devices or components known in the art may be used as the laser waveguide device and the ultrasonic waveguide device of the present application, and a flexible waveguide device or component is preferably used.
The laser generator may be any of a variety of prior art laser emitting components or components such as a laser or laser diode, etc. The acousto-optic modulator, the ultrasonic oscillating circuit and the ultrasonic transducer may be any one of the prior art corresponding components or parts having the same or similar functions. The control component may be a control circuit board, a control chip or a microcomputer such as an industrial personal computer or the like.
The acousto-optic generating device 10 is electrically connected to the control component, and the acousto-optic generating device 10 can emit laser or ultrasonic wave independently and can also emit the laser and the ultrasonic wave simultaneously. Preferably, the acousto-optic generating device 10 can emit any one or more of 193-337nm ultraviolet light, 488nm blue light, 514nm green light, 633nm red light, 1064nm near-infrared light and 570-650nm dimmable light, and the frequency of the ultrasonic waves generated by the acousto-optic generating device 10 is 100kHz to 2 MHz.
Description of the mode: 1. the system comprises a photodynamic therapy (PDT) mode, a laser generator and an acousto-optic modulator in an activated state, and an ultrasonic oscillation circuit and an ultrasonic transducer in a deactivated state. The laser intensity and frequency can be adjusted to appropriate levels by the laser intensity adjusting unit 20 and the laser frequency adjusting unit 30, and the adjusted laser beam is guided to the affected part by the laser waveguide device 80. 2. And (3) the sound power treatment (SDT), the laser generator and the sound light modulator are in a closed state, and the ultrasonic oscillation circuit and the ultrasonic transducer are in an activated state. The intensity and frequency of the ultrasonic waves can be adjusted to appropriate levels by the ultrasonic intensity adjusting unit 40 and the ultrasonic frequency adjusting unit 50, and the adjusted ultrasonic waves are transmitted to the affected part by the ultrasonic waveguide device 90. 3. In the photoacoustic power combined treatment mode, the laser generator, the acousto-optic modulator, the ultrasonic oscillation circuit and the ultrasonic transducer are all in a starting state. The laser and the ultrasonic wave can be transmitted to the affected part sequentially or simultaneously through the laser waveguide device 80 and the ultrasonic waveguide device 90, and the intensity of the laser and the ultrasonic wave can be adjusted through the laser intensity adjusting part 20, the laser frequency adjusting part 30, the ultrasonic intensity adjusting part 40 and the ultrasonic frequency adjusting part 50. According to clinical comparison, the curative effect of the photoacoustic-dynamic combined synchronous treatment mode is superior to that of the photodynamic treatment (PDT) mode and the photodynamic treatment (SDT) mode, and that of the photoacoustic-dynamic combined asynchronous treatment mode.
The application provides a portable acousto-optic power device which can be used for noninvasive treatment of superficial and deep tissue diseases simultaneously by combining an acousto-optic power technology. Compared with the prior art, the method has the technical effects of convenient and simple operation, small dosage of the sensitizing agent, guaranteed treatment effect and the like.
Second preferred embodiment
Referring to fig. 2, the present embodiment discloses another photoacoustic powered therapeutic apparatus, which includes a housing, an acousto-optic generator 10, a laser display 60, a photoacoustic wave guide device 100 and a control component. The functions and connections of the cabinet, the acousto-optic generator 10, the laser display 60 and the control unit are the same as those of the first preferred embodiment. Reference may be made to the implementation by those skilled in the art.
The acousto-optic generation device 10 in the present embodiment includes a laser generator 110, an acousto-optic transmission tunnel 120, and an acousto-optic synchronization part 130; the laser generator 110 is used for emitting laser, the acousto-optic synchronization component 130 is used for forming an annular array laser source and generating ultrasonic waves through cooperation of the acousto-optic transmission tunnel 120, and the acousto-optic transmission tunnel 120 is used for transmitting the laser and the ultrasonic waves generated by the acousto-optic synchronization component 130 and transmitting the acousto-optic energy to the photoacoustic waveguide 100. The photoacoustic wave guide device 100 is used to guide photoacoustic energy to a region of a patient.
The cross section of the acousto-optic transmission tunnel 120 has a perfect circular structure; the acousto-optic synchronization component 130 comprises a cylindrical part 1310 and a conical part 1320, wherein annular grating arrays 1330 which are mutually communicated are arranged inside the cylindrical part 1310 and the conical part 1320; the acousto-optic synchronizing member 130 is disposed in the acousto-optic transmission tunnel 120 and coincides with the axis of the acousto-optic transmission tunnel 120, and the conical portion 1320 of the acousto-optic synchronizing member 130 faces the incident end of the laser light.
The laser generator may be any of a variety of prior art laser emitting components or components such as a laser or laser diode, etc. Preferably, the laser generator 110 can emit any one or more of 193-337nm ultraviolet light, 488nm blue light, 514nm green light, 633nm red light, 1064nm near-infrared light and 570-650nm dimmable light. The frequency of the ultrasonic waves generated by the acousto-optic synchronizing section 130 and the acousto-optic transmission tunnel 120 is between 100kHz and 2 MHz.
The acousto-optic transmission tunnel 120 may be any waveguide component or assembly known in the art that is capable of conducting both laser light and ultrasound, preferably a metallic material such as aluminum. The photoacoustic waveguide device 100 may be any of a variety of waveguide devices or components known in the art, preferably a flexible waveguide device or component.
Description of the principle: the laser beam emitted from the laser generator is irradiated onto the acousto-optic synchronization element 130, a portion of which is reflected by the conical reflection surface of the conical portion 1320 onto the inner surface of the acousto-optic transmission tunnel 120 to form an annular laser spot, and another portion of which forms a concentric annular laser source as shown by the arrow direction portion in fig. 2 through the annular grating array 1330. The inner surface of the acousto-optic transmission tunnel 120 generates longitudinal waves, transverse waves and surface waves under the action of the annular laser spot, and the longitudinal waves, the transverse waves and the surface waves are coupled into ultrasonic guided waves in the conduction process. The ultrasonic guided wave and the annular laser source are conducted to the affected part through the photoacoustic wave guide device 100 to realize acousto-optic synchronous treatment.
The photoacoustic power therapeutic apparatus provided by the embodiment can be used for noninvasive acousto-optic synchronous treatment of superficial and deep tissue diseases, and has the technical effects of uniform energy distribution, good photoacoustic signal synchronization performance, simplicity in operation, convenience in use and the like. Meanwhile, the annular laser source is adopted as the laser source for acousto-optic synchronous treatment in the embodiment, and the technical effects of high energy efficiency, small side effect on a human body, higher safety performance and the like are achieved.
In another modified embodiment of this embodiment, the acousto-optic generating device 10 further includes a laser beam expander, which is disposed between the laser generator 110 and the acousto-optic synchronizing component 130, and is used for adjusting the radiation pattern of the laser beam.
In another variation of this embodiment, the acousto-optic generator 10 further includes an acousto-optic modulator for adjusting the intensity and frequency of the concentric ring laser source formed by the ring grating array 1330.
While the technical solutions and technical effects of the present application have been described in detail with reference to the drawings and specific embodiments of the present application, it should be noted that the specific embodiments disclosed in the specification are only preferred embodiments of the present application, and other embodiments may be developed by those skilled in the art based on the specific embodiments; any simple modifications and equivalents which do not depart from the innovative concepts of the present application are intended to be included within the scope of the present patent.

Claims (10)

1. The utility model provides a photoacoustic power therapeutic instrument, includes quick-witted case, its characterized in that: the device also comprises an acousto-optic generating device (10) and a control component; the acousto-optic generating device (10) and the control component are both arranged in the case;
the acousto-optic generating device (10) is electrically connected to the control part; the acousto-optic generating device (10) can emit laser or ultrasonic wave independently and can also emit the laser and the ultrasonic wave simultaneously.
2. The photoacoustic kinetic therapy instrument of claim 1, wherein:
the acousto-optic generating device (10) comprises a laser generator, an acousto-optic modulator, an ultrasonic oscillation circuit and an ultrasonic transducer;
the laser generator and the ultrasonic oscillation circuit are electrically connected to the control component, the laser generator is used for emitting laser, the acousto-optic modulator is used for adjusting the laser emitted by the laser generator, the ultrasonic oscillation circuit is used for generating ultrasonic oscillation, and the ultrasonic transducer is used for converting the ultrasonic oscillation generated by the ultrasonic oscillation circuit into ultrasonic waves.
3. The photoacoustic kinetic therapy instrument of claim 1, wherein:
the acousto-optic generation device (10) comprises a laser generator (110), an acousto-optic transmission tunnel (120) and an acousto-optic synchronization component (130); the laser generator (110) is used for emitting laser, the acousto-optic synchronous component (130) is used for forming an annular array laser source and generating ultrasonic waves through cooperation of the acousto-optic transmission tunnel (120), and the acousto-optic transmission tunnel (120) is used for transmitting the laser and the ultrasonic waves generated by the acousto-optic synchronous component (130).
4. The photoacoustic kinetic therapy instrument of claim 3, wherein:
the cross section of the acousto-optic transmission tunnel (120) has a perfect circular structure;
the acousto-optic synchronous component (130) comprises a cylindrical part (1310) and a conical part (1320), and annular grating arrays (1330) which are mutually communicated are arranged inside the cylindrical part (1310) and the conical part (1320);
the acousto-optic synchronous component (130) is arranged in the acousto-optic transmission tunnel (120), the axes of the acousto-optic synchronous component (130) and the acousto-optic transmission tunnel (120) are coincident with each other, and the conical part (1320) of the acousto-optic synchronous component (130) faces to the incident end of laser.
5. The photoacoustic kinetic therapy instrument of claim 3, wherein:
the acousto-optic generation device (10) further comprises a laser beam expander, and the laser beam expander is arranged between the laser generator (110) and the acousto-optic synchronous component (130) and used for adjusting the radiation form of the laser beam.
6. The photoacoustic kinetic therapy instrument of claim 4, wherein:
the acousto-optic generation device (10) further comprises an acousto-optic modulator for adjusting the intensity and frequency of the concentric ring-shaped laser source formed by the ring-shaped grating array (1330).
7. The photoacoustic kinetic therapy instrument of claim 1, wherein: the acousto-optic generating device (10) can emit one or more of 193-337nm ultraviolet light, 488nm blue light, 514nm green light, 633nm red light, 1064nm near-infrared light and 570-650nm dimmable light; the ultrasonic frequency generated by the acousto-optic generating device (10) is 100kHz to 2 MHz.
8. The photoacoustic kinetic therapy instrument of any one of claims 1 to 7, wherein: the photoacoustic power therapeutic apparatus further comprises a laser intensity adjusting component (20), a laser frequency adjusting component (30), an ultrasonic intensity adjusting component (40) and an ultrasonic frequency adjusting component (50);
the laser intensity adjusting component (20), the laser frequency adjusting component (30), the ultrasonic intensity adjusting component (40) and the ultrasonic frequency adjusting component (50) are arranged in and/or on the case;
the laser intensity adjusting component (20), the laser frequency adjusting component (30), the ultrasonic intensity adjusting component (40) and the ultrasonic frequency adjusting component (50) are all electrically connected to the control component.
9. The photoacoustic kinetic therapy instrument of any one of claims 1 to 7, wherein:
the photoacoustic power therapeutic apparatus also comprises a laser display (60), an ultrasonic display (70), a laser waveguide device (80) and an ultrasonic waveguide device (90);
the laser display (60), the ultrasonic display (70), the laser waveguide device (80) and the ultrasonic waveguide device (90) are all arranged in and/or on the case;
the laser display (60) and the ultrasonic display (70) are both electrically connected to the control component, and the laser waveguide device (80) and the ultrasonic waveguide device (90) are both electrically connected to the acousto-optic generating device (10).
10. The photoacoustic kinetic therapy instrument of any one of claims 1 to 7, wherein:
the photoacoustic power therapeutic apparatus also comprises a photoacoustic wave guide device (100); the photoacoustic wave guide device (100) is used for transmitting laser and/or ultrasonic waves.
CN202120135125.0U 2021-01-19 2021-01-19 Photoacoustic power therapeutic instrument Active CN215136069U (en)

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Application Number Priority Date Filing Date Title
CN202120135125.0U CN215136069U (en) 2021-01-19 2021-01-19 Photoacoustic power therapeutic instrument

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202120135125.0U CN215136069U (en) 2021-01-19 2021-01-19 Photoacoustic power therapeutic instrument

Publications (1)

Publication Number Publication Date
CN215136069U true CN215136069U (en) 2021-12-14

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