CN215130818U

CN215130818U - Big mouse and small mouse stomach filling needle

Info

Publication number: CN215130818U
Application number: CN202120307966.5U
Authority: CN
Inventors: 张璞; 韩海燕; 张帆; 曹汐; 李莎; 杨柳
Original assignee: Chongqing Institute for Food and Drug Control
Current assignee: Chongqing Institute for Food and Drug Control
Priority date: 2021-02-02
Filing date: 2021-02-02
Publication date: 2021-12-14
Anticipated expiration: 2031-02-02

Abstract

The utility model discloses a safe nontoxic and big mouse gavage needle that can disinfect repeatedly and use, including pintle, needle stalk and the syringe needle that connects gradually, pintle, needle stalk and syringe needle are hollow structure, and communicate in proper order, the needle stalk includes that outer pipe and cover establish the inlayer pipe in outer pipe, outer pipe and inlayer pipe are the polyethylene pipe. The utility model discloses the needle stalk part of gavage needle comprises double-deck polyethylene pipe, and the safe nontoxic and use of disinfecting repeatedly of polyethylene material is compared with traditional gavage needle, long service life and the risk that does not have metal coating and drops.

Description

Big mouse and small mouse stomach filling needle

Technical Field

The utility model relates to a big mouse gavage test device especially relates to a big mouse gavage needle.

Background

Oral administration is the safest, convenient and economical mode of administration for a drug, and therefore most drugs are preferably administered orally during formulation development. In the preclinical test of new drugs, oral gavage of experimental animals is a mode of simulating oral administration of human drugs, the method is simple and convenient to operate, the administration dosage is accurate, solution or suspension can be infused, repeated administration can be achieved, and the method is suitable for various experimental animals such as mice and rats.

Most of the existing gastric perfusion needles are made of stainless steel materials, and the following problems exist in the use process: firstly, the material is rigid and can not deform, and the airway or the esophagus is easy to hurt during operation, so that the experimental animal is gradually thinned, even the internal organs of the mouse are injured, the mouse is dead, and the experiment fails; secondly, the depth of the needle insertion is difficult to master, and the depth of the needle insertion is difficult to find for beginners; thirdly, the metal coating is easy to fall off after multiple disinfection or long-term use, and the service life is limited.

Therefore, those skilled in the art are working on developing a safe, nontoxic, and repeatedly sterilizable mouse and rat gavage needle.

SUMMERY OF THE UTILITY MODEL

In view of the above-mentioned defects of the prior art, the technical problem to be solved by the present invention is to provide a safe, nontoxic and reusable gavage needle for rats and mice.

In order to achieve the purpose, the utility model provides a big mouse stomach filling needle, including the pintle, needle stalk and the syringe needle that connect gradually, pintle, needle stalk and syringe needle are hollow structure, and communicate in proper order, the needle stalk includes that outer pipe and cover establish the inlayer pipe in outer pipe, outer pipe and inlayer pipe are the polyethylene pipe.

Preferably, a gap is arranged between the outer layer pipe and the inner layer pipe, and a steel wire is arranged in the gap.

Preferably, the steel wire is spirally wound on the inner-layer pipe.

Preferably, the outer peripheral surface of the outer layer pipe is provided with a plurality of scale indication points.

Preferably, the distance between two adjacent scale indication points is 0.5 cm.

Preferably, the front end of the needle head is provided with a liquid outlet hole, and the aperture of the liquid outlet hole is smaller than the inner diameter of the inner-layer tube.

Preferably, the needle head is integrally arranged on the needle stem.

Preferably, the needle head is a polyethylene tube with a single-layer structure.

Preferably, the pintle is a stainless steel tube.

Preferably, the pintle and the needle stem are bonded by epoxy resin glue.

The utility model has the advantages that: the utility model discloses the needle stalk part of gavage needle comprises double-deck polyethylene pipe, and the safe nontoxic and use of disinfecting repeatedly of polyethylene material is compared with traditional gavage needle, long service life and the risk that does not have metal coating and drops.

Drawings

Fig. 1 is a schematic structural view of a rat and a mouse gastric lavage needle in an embodiment of the invention.

Fig. 2 is a schematic sectional view of the gavage needle for rats and mice according to an embodiment of the present invention.

Fig. 3 is an enlarged schematic view of a portion P in fig. 2.

Detailed Description

The present invention will be further described with reference to the accompanying drawings and examples, wherein it is noted that, in the description of the invention, the terms "upper", "lower", "left", "right", "inner", "outer", etc. indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular manner, and therefore should not be construed as limiting the present invention. The terms "first," "second," "third," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

As shown in fig. 1-3, a rat and mouse stomach irrigation needle comprises a pintle 10, a needle stalk 20 and a needle head 30 which are connected in sequence, wherein the pintle 10, the needle stalk 20 and the needle head 30 are all hollow structures and are communicated in sequence, the needle stalk 20 comprises an outer layer tube 21 and an inner layer tube 22 sleeved in the outer layer tube 21, and the outer layer tube 21 and the inner layer tube 22 are both polyethylene tubes.

A gap 23 is provided between the outer layer tube 21 and the inner layer tube 22, and a steel wire 24 is provided in the gap 23.

The needle stem part of the gastric perfusion needle consists of a double-layer polyethylene tube with a thin steel wire, and the polyethylene material is safe, non-toxic and capable of being repeatedly sterilized and used, and compared with the traditional gastric perfusion needle, the gastric perfusion needle is long in service life and free of risk of falling of a metal coating.

The steel wire 24 is spirally wound around the inner tube 22. The double-layer tube contains the spirally wound steel wire, so that the plasticity of the needle stalk is increased, the advantages of the traditional straight head and elbow gastric perfusion needle are integrated, the needle can be bent along with the shape of the esophagus when in use, and the compliance is good.

The outer peripheral surface of the outer layer tube 21 is provided with a plurality of scale indication points 25.

The distance between two adjacent scale indication points 25 is 0.5 cm.

The scale indication points on the surface of the outer layer tube are convenient for the experimenter to directly and accurately observe the needle insertion depth, and the problem of inaccurate needle insertion position caused by insufficient experience of the beginner gastric lavage experimenter is solved; when the traditional gastric perfusion needle is used for testing, different types of gastric perfusion needles are generally selected according to the age of a mouse, the replacement is frequently needed in the test, the test speed is influenced, after the scale indication points are arranged, the needle can be inserted according to the empirical value of the distance from the oral cavity to the stomach of the test mouse, and the mouse only needs one type of gastric perfusion needle, so that the operation of needle replacement is avoided.

The front end of the needle 30 is provided with a liquid outlet hole 31, and the aperture of the liquid outlet hole 31 is smaller than the inner diameter of the inner layer tube 22.

The needle 30 is integrally provided on the needle stem 20.

The needle 30 is a polyethylene tube of single-layer structure. The needle head is designed to be made of soft plastic materials, so that the esophagus of the animal can be protected from being stabbed.

The pintle 10 is a stainless steel tube.

In this embodiment, the pintle 10 and the needle stem 20 are bonded by epoxy glue. The length of the needle is 0.5cm, and the aperture of the liquid outlet hole 31 is 0.2mm smaller than the inner diameter of the inner tube 22.

The foregoing has described in detail preferred embodiments of the present invention. It should be understood that numerous modifications and variations can be devised by those skilled in the art in light of the teachings of the present invention without undue experimentation. Therefore, the technical solutions that can be obtained by a person skilled in the art through logic analysis, reasoning or limited experiments based on the prior art according to the concepts of the present invention should be within the scope of protection defined by the claims.

Claims

1. A kind of big and small mouse stomach perfusion needle, its characteristic is: including pintle (10), needle stalk (20) and syringe needle (30) that connect gradually, pintle (10), needle stalk (20) and syringe needle (30) are hollow structure, and communicate in proper order, needle stalk (20) include outer pipe (21) and cover establish inlayer pipe (22) in outer pipe (21), outer pipe (21) and inlayer pipe (22) are the polyethylene pipe.

2. The rat and mouse gastric lavage needle as claimed in claim 1, which is characterized in that: a gap (23) is arranged between the outer layer pipe (21) and the inner layer pipe (22), and a steel wire (24) is arranged in the gap (23).

3. The rat and mouse gastric lavage needle as claimed in claim 2, which is characterized in that: the steel wire (24) is spirally wound on the inner layer pipe (22).

4. The rat and mouse gastric lavage needle as claimed in claim 1, 2 or 3, characterized in that: the outer peripheral surface of the outer layer pipe (21) is provided with a plurality of scale indication points (25).

5. The rat and mouse gastric lavage needle of claim 4, which is characterized in that: the distance between two adjacent scale indication points (25) is 0.5 cm.

6. The rat and mouse gastric lavage needle as claimed in claim 1, 2 or 3, characterized in that: the front end of syringe needle (30) is equipped with out liquid hole (31), the aperture that goes out liquid hole (31) is less than the internal diameter of inlayer pipe (22).

7. The rat and mouse gastric lavage needle as claimed in claim 1, 2 or 3, characterized in that: the needle head (30) is integrally arranged on the needle stem (20).

8. The rat and mouse gastric lavage needle as claimed in claim 1, 2 or 3, characterized in that: the needle (30) is a polyethylene tube with a single-layer structure.

9. The rat and mouse gastric lavage needle as claimed in claim 1, 2 or 3, characterized in that: the pintle (10) is a stainless steel tube.

10. The rat and mouse gastric lavage needle as claimed in claim 1, 2 or 3, characterized in that: the pintle (10) is bonded with the needle stem (20) through epoxy resin glue.