CN215078602U

CN215078602U - Blood suction device

Info

Publication number: CN215078602U
Application number: CN202121480969.5U
Authority: CN
Inventors: 鲍伟胜; 鲍岳洋; 王春雷
Original assignee: Anhui Beiming Biotechnology Co ltd
Current assignee: Anhui Beiming Biotechnology Co ltd
Priority date: 2021-06-29
Filing date: 2021-06-29
Publication date: 2021-12-10
Anticipated expiration: 2031-06-29

Abstract

The utility model relates to a blood suction device, which comprises a core rod and a core rod bracket, wherein the external structure of the core rod is a three-cylinder body which comprises an upper section, a middle section and a lower section with different diameters and is integrated; the inner center of the core rod is provided with an aperture along the axial direction, and the needle head can penetrate through the core rod through the aperture; the diameter of the middle section cylinder outside the core rod is the largest, and the diameter of the lower end cylinder is the smallest; the inner part of the mandrel support is a columnar structure with a hollow structure, the hollow structure in the mandrel support is matched with the outer structure of the mandrel, namely the inner part of the mandrel support comprises an upper section, a middle section and a lower section which are consistent with the outer structure of the mandrel and are three integrated cylindrical cavities; the core rod is placed in a cavity in the core rod support. The utility model can make the blood collecting tube be very convenient and fast to be inserted and taken down when the blood passes through the blood circulation tumor cell capturing device; meanwhile, the needle head can penetrate into the blood collecting tube without obstacle; possible blockage of the needle is eliminated in the blood suction process; the dredging treatment of the blood circulation pipeline is convenient.

Description

Blood suction device

Technical Field

The utility model relates to a blood suction means technical field, concretely relates to blood suction means.

Background

Ctc (circulating Tumor cells) refers to Tumor cells that enter the blood circulation. Some CTCs may escape from immune recognition or drug therapy, find a suitable microenvironment in vivo, form "seeds" for plant growth in distant tissues, organs or primary tissues, cause metastasis or recurrence of tumors. CTC detection is one method of determining mobile cancer cells in the blood. Detection of CTCs allows identification of very early stage microscopic cancers that cannot be visualized by imaging, early clinical tumor discovery, and very early stage cancer metastasis or recurrence.

There are two methods currently available for the detection of CTCs. One is an antigen-antibody approach based on the expression of specific antigens on the surface of tumor cells, such as the first CellSearch technique and instrument approved by FDA in the united states. Another is ISET technique based on cell shape and size, which is based on the characteristic that tumor cells are bigger than normal blood cells, and the tumor cells in the blood are left on the membrane of the chip by means of hemofiltration.

The ISET technology involves three major steps, namely blood suction, filtration and blood outflow. The aspiration of blood is a very critical step. At present, the conventional method is to deeply insert the needle into the blood collection tube to suck blood by using negative pressure, and the design of the needle device is relatively complex. On one hand, the needle device is provided with an opening, so that the liquid level in the blood collection tube keeps pressure balance with the outside; on the other hand, the blood collection tube is tightly combined with the blood collection tube. This is a design inconvenience for blood handling.

Specifically, the prior art has the following problems:

closely combine blood collecting tube and syringe needle connecting device: a rubber cover is used, and a hole is punched in the middle of the rubber cover, or other structures are adopted to ensure that the tube is tightly combined with the needle connecting device to prevent the blood collecting tube from falling off. In order to balance the pressure difference between the inside and outside of the blood collecting tube, the needle device must have an outlet which is communicated with the outside and is easily covered by tight combination to block the pressure difference between the inside and outside of the blood collecting tube, thereby influencing the blood suction.

The blood collecting tube is inconvenient to insert and take down, and due to the tight combination of the blood collecting tube and the needle connecting device, certain force is needed, so that the needle is easy to be partially stressed and bent in the treatment process, the circulation of blood is influenced, and the complete absorption of the blood in the blood collecting tube is influenced finally;

the connection and the fixation of the prior device, once the circulation in the blood circulation pipeline has problems, the visual field is not exposed greatly, so that the device is not easy to process.

SUMMERY OF THE UTILITY MODEL

The utility model provides a pair of blood suction means can solve above-mentioned technical problem.

In order to achieve the above purpose, the utility model adopts the following technical scheme:

a blood suction device comprises a core rod and a core rod bracket, wherein the external structure of the core rod is three cylinders which comprise an upper section, a middle section and a lower section with different diameters and are integrated;

the inner center of the core rod is provided with an aperture along the axial direction, and the needle head can penetrate through the core rod through the aperture;

the diameter of the middle section cylinder outside the core rod is the largest, and the diameter of the lower end cylinder is the smallest;

the inner part of the mandrel support is a columnar structure with a hollow structure, the hollow structure in the mandrel support is matched with the outer structure of the mandrel, namely the inner part of the mandrel support comprises an upper section, a middle section and a lower section which are consistent with the outer structure of the mandrel and are three integrated cylindrical cavities;

the core rod is placed in a cavity in the core rod support.

The outer structure of the core rod support is a cylindrical structure which comprises an upper section and a lower section which have different diameters and are integrated, and the outer diameter of the lower section cylinder of the core rod support is larger than that of the upper section cylinder;

the outer part of the upper section of the cylinder of the mandrel support is provided with a thread structure matched with the outer nut.

Furthermore, the top caliber of the outer nut, namely the diameter of the inlet of the outer nut, is larger than or equal to the outer diameter of the upper section cylinder of the mandrel, and the diameter of the inlet of the outer nut is smaller than the outer diameter of the middle section cylinder of the mandrel.

The core rod support is characterized by further comprising a fixing frame, wherein the fixing frame is of a flat plate structure, and at least one core rod support inserting hole is formed in the fixing frame;

the diameter of the insertion opening of the core rod support is larger than or equal to the outer diameter of the lower section cylinder of the core rod support, and the diameter of the insertion opening of the core rod support is smaller than the outer diameter of the outer nut.

Furthermore, a groove is arranged on the inner wall of the lower section cylindrical cavity of the mandrel support, and a sealing ring is arranged in the groove.

According to the technical scheme, the core rod of the utility model adopts different sections of cylinders with different diameters, the diameter of the lower section of cylinder is smaller than that of the blood collecting tube, so that the balance of the pressure inside and outside the blood collecting tube is maintained, and the blood is absorbed under negative pressure; the diameter of the middle cylinder is larger than the caliber of the blood collecting tube, so that the blood collecting tube is prevented from continuously rising in the inserting process, and the needle is prevented from touching the bottom of the blood collecting tube; the upper thread design of the mandrel holder, which becomes engaged with the external nut, thus fixing the structure as a whole; the design of the lower groove fixes the blood collecting tube by the extrusion of the sealing ring; the aperture of the lower part is slightly larger than the diameter of the lower cylinder of the core rod, so that the blood collecting tube can be conveniently inserted.

The utility model discloses whole design concept is very ingenious, utilizes polytetrafluoroethylene's light material, and the extrusion through space between sealing washer and the cylinder is used for reaching the purpose of fixed blood collecting pipe. The operation is very convenient; the whole operation process has almost no damage to the needle head, can not cause the bending of the needle head-blood flow pipeline, and can not influence the blood suction; the visual field exposure between the blood transport tubing to which the upper portion of the needle is connected is relatively large. Once the pipeline is blocked due to factors such as blood coagulation and the like, the plastic pipeline is convenient to dredge. The polytetrafluoroethylene is adopted, so that the hardness, heat resistance and cold resistance are better.

Generally speaking, the utility model discloses a blood suction device's beneficial effect as follows:

1. the blood collecting tube can be conveniently and rapidly inserted and taken down when blood passes through the blood circulation tumor cell capturing device;

2. meanwhile, the needle head can penetrate into the blood collecting tube without obstacle;

3. possible blockage of the needle is eliminated in the blood suction process; the dredging treatment of the blood circulation pipeline is convenient.

Drawings

Fig. 1 is a schematic structural diagram of the present invention;

FIG. 2 is a schematic view of the core rod structure of the present invention;

FIG. 3 is a schematic view of the core rod support structure of the present invention;

FIG. 4 is a schematic structural view of the outer nut of the present invention;

fig. 5 is a schematic view of the fixing frame of the present invention.

1. A core rod; 2. a needle inlet; 3. the lower end of the core rod; 4. a needle outlet; 5. a mandrel holder; 6. a mandrel inlet; 7. a core rod support thread structure; 8. a core rod support sealing ring; 9. a mandrel outlet; 10. an outer nut; 11. an outer nut inlet; 12. an outer nut outlet; 13. the joint of the mandrel bracket and the outer nut; 14. a needle head; 15. a blood collection tube; 16. a fixed mount; 17. the core rod support is inserted into the opening.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention.

As shown in FIG. 1, the blood sucking device of the present embodiment is composed of three parts: the core rod 1, the core rod support 5 and the external nut 10 are made of polytetrafluoroethylene or similar materials, the core rod 1, the core rod support 5 and the external nut 10 are independent bodies, and each part is integrally formed.

Namely, the external structure of the core rod 1 is three cylinders which comprise an upper section, a middle section and a lower section with different diameters and are integrated;

the inner center of the core rod 1 is provided with an aperture along the axial direction, and the needle head 14 can penetrate through the core rod 1 through the aperture;

the diameter of the middle section cylinder outside the core rod 1 is the largest, and the diameter of the lower end cylinder is the smallest;

the inner part of the core rod support 5 is a columnar structure with a hollow structure, the hollow structure in the core rod support 5 is matched with the outer structure of the core rod 1, and the core rod 1 is placed in the core rod support 5;

the hollow structure inside the mandrel support 5 is matched with the external structure of the mandrel 1, and can be interpreted that the inside of the mandrel support 5 is provided with three cylindrical cavities which are consistent with the outside of the mandrel 1, comprise an upper section, a middle section and a lower section and are integrated, so that after the mandrel 1 is placed in the mandrel support 5, the mandrel 1 can be clamped at the position due to the limitation of the lowest section cavity inside the mandrel support 5 because the diameter of the lower section is smaller than the interrupted cavity diameter, and the effect of supporting and fixing the mandrel 1 is achieved;

specifically, the outer structure of the mandrel holder 5 is a cylindrical structure which comprises an upper section and a lower section which have different diameters and are integrated, and the outer diameter of the lower section of the cylinder of the mandrel holder 5 is larger than that of the upper section of the cylinder; the outer part of the upper section of the cylinder of the mandrel support 5 is provided with a thread structure matched with the outer nut 10. The reason for setting the lower part and the upper part of the outer diameter of the mandrel support 5 is to further limit the outer nut 10, so that the outer nut 10 is more firm after being screwed up.

The top caliber of the outer nut 10, namely the diameter of the outer nut inlet 11 is larger than or equal to the outer diameter of the upper section cylinder of the mandrel 1, and the diameter of the outer nut inlet 11 is smaller than the outer diameter of the middle section cylinder of the mandrel 1, and the arrangement is that the upper section cylinder structure of the mandrel 1 can penetrate through the outer nut 10 to be exposed, the middle section cylinder structure of the mandrel 1 can not penetrate through, the limiting effect on the mandrel 1 is achieved, and the mandrel 1 is fixed more stably;

the core rod support is characterized by further comprising a fixing frame 16, wherein the fixing frame 16 is of a flat plate structure, and at least one core rod support inserting hole 17 is formed in the fixing frame 16; the diameter of the plug holder insertion opening 17 is equal to or larger than the outer diameter of the lower cylinder of the plug holder 5, and the diameter of the plug holder insertion opening 17 is smaller than the outer diameter of the outer nut 10. The holder 16 is used for placing the mandrel bar 5, and a plurality of mandrel bar insertion ports 17 may be provided as necessary.

The following are further detailed below:

the structure of the core rod 1 is shown in the figure; the core rod 1 is composed of an upper section, a middle section and a lower section which have different diameters. The core rod 1 has a central bore diameter corresponding to the outer diameter of the needle 14. The needle 14 extends through the core rod through the aperture.

Upper section cylinder of core rod 1: and the core rod is matched with the outer nut to play a role in fixing the core rod.

Middle section cylinder of core rod 1: its diameter is the largest. The diameter of the blood collecting tube is obviously larger than the caliber of the blood collecting tube, and when the blood collecting tube is inserted, the lower end of the middle section cylinder plays a role in preventing further advancing.

Lower section cylinder of core rod 1: its diameter is minimal. The diameter of the lower section of the core rod 1 is smaller than the caliber of the blood collecting tube 15, after the blood collecting tube 15 is inserted, the lower end 3 of the core rod extends into the blood vessel collection, the lower end can move up and down freely and is communicated with the outside, so that the pressure of the liquid level of the blood in the blood vessel is ensured to be consistent with the outside, and the blood can be sucked through the negative pressure at the tail end of the needle head.

The blood collection tube 15 is inserted from the end of the core rod 1 until the intersection of the lower and middle section cylinders of the core rod. The diameter of the middle cylinder is far larger than the caliber of the blood collecting tube, so that the blood collecting tube is prevented from going upwards. However, the blood collection tube is fixed by the sealing ring of the core rod support.

A core rod support 5: mainly comprises an upper threaded cylinder and a lower cylinder.

The center of the cylinder is through, which facilitates the insertion of the core rod 1. The thread on the upper cylinder and the outer nut 10 form a screw-nut structure, which facilitates the fixation of the whole structure.

The lower end of the mandrel holder 5 has a through hole in the lower cylinder, the diameter of the hole being slightly larger than the diameter of the lower cylinder of the mandrel. When the core rod is inserted, a certain amount of clearance is reserved between the lower end column of the core rod and the through holes at the lower end of the core rod support around the lower end column of the core rod. This gap is where the blood collection tube is inserted.

The inner wall of the lower end cylindrical hole is provided with a groove which is a placing position of the sealing ring 8. The sealing ring 8 is used to fix the blood collection tube 15. After the blood collecting tube 15 is inserted, the extrusion effect of the sealing ring 8 in the groove at the position is utilized to reduce the gap between the outer wall of the blood collecting tube 15 and the cylindrical through hole at the lower end of the core rod bracket, thereby playing the role of fixing the blood collecting tube 15.

External nut

The external nut 10 is matched with the thread structure at the upper end of the mandrel support 5; there are two openings respectively. The diameter of the outer nut inlet 11 is slightly larger than that of the upper section cylinder of the core rod, but is smaller than that of the middle section cylinder of the core rod, so that the core rod is prevented from being ejected out when the blood collecting tube is inserted; the diameter of the outer nut outlet 12 is matched with the diameter of the upper end thread cylinder of the core rod support.

The blood inflow device can be fixed to a certain portion of the instrument by the external nut 10 being screwed to the corresponding mandrel holder and by the fixing frame 16.

The working process of the utility model is as follows:

1. an aluminum or steel mount 16 is fixed to the instrument somewhere to facilitate docking with the blood transport tubing;

2. the needle head passes through the core rod from the inlet of the core rod 1 to the outlet;

3. the core rod 1 is placed in the core rod bracket 5;

4. the upper section of the cylinder of the mandrel support 5 penetrates out of the lower inlet of the fixed frame 16; the diameter of the inlet of the fixed frame 16 is slightly smaller than the diameter of the lower section of the cylinder of the mandrel support, so that the mandrel support is clamped on the fixed frame;

5. an outer nut 10 is placed on the upper end of the mandrel holder 5, and the outer nut 10 is tightened until no further tightening is possible. The whole structure is fixed;

6. the blood collecting tube is inserted from the lower end of the core rod bracket 5 along the needle head, and the lower end of the core rod can enter the opening of the blood tube; continuing to insert the tube upwards until the open end of the tube abuts against the middle cylinder of the core rod and cannot continue to advance; meanwhile, the existence of the sealing ring 8 at the lower section of the core rod bracket plays a role of extrusion, so that the blood collecting tube is fixed;

7. the structure design can keep the liquid in the blood collecting tube communicated with the outside and the pressure balance while fixing the blood collecting tube; thus, the negative pressure applied to the tip of the needle can easily suck out the blood in the blood collection tube.

To sum up, the core rod of the utility model adopts different sections of cylinders with different diameters, and the diameter of the cylinder of the lower section is smaller than the caliber of the blood collecting tube, so as to maintain the balance of the internal and external pressure of the blood collecting tube and help the blood to be absorbed under negative pressure; the diameter of the middle cylinder is larger than the caliber of the blood collecting tube, so that the blood collecting tube is prevented from continuously rising in the inserting process, and the needle is prevented from touching the bottom of the blood collecting tube; the upper thread design of the mandrel holder, which becomes engaged with the external nut, thus fixing the structure as a whole; the design of the lower groove fixes the blood collecting tube by the extrusion of the sealing ring; the aperture of the lower part is slightly larger than the diameter of the lower cylinder of the core rod, so that the blood collecting tube can be conveniently inserted.

The above embodiments are only used to illustrate the technical solution of the present invention, and not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention in its corresponding aspects.

Claims

1. A blood suction device comprises a core rod (1) and a core rod bracket (5),

the external structure of the core rod (1) is three cylinders which comprise an upper section, a middle section and a lower section with different diameters and are integrated;

the inner center of the core rod (1) is provided with an aperture along the axial direction, and the needle head (14) can penetrate through the core rod (1) through the aperture;

the diameter of a middle section cylinder outside the core rod (1) is the largest, and the diameter of a lower end cylinder is the smallest;

the inner part of the mandrel support (5) is of a columnar structure with a hollow structure, the hollow structure in the mandrel support (5) is matched with the outer structure of the mandrel (1), namely, the inner part of the mandrel support (5) comprises an upper section, a middle section and a lower section which are consistent with the outer structure of the mandrel (1) and are three integrated cylindrical cavities;

the core rod (1) is placed in a cavity in the core rod bracket (5).

2. The blood aspiration device of claim 1, wherein:

the outer nut (10) is further included, the outer structure of the mandrel support (5) is a cylindrical structure which comprises an upper section and a lower section which have different diameters and are integrated, and the outer diameter of the lower section of cylinder of the mandrel support (5) is larger than that of the upper section of cylinder;

the outer part of the upper section of the cylinder of the core rod bracket (5) is provided with a thread structure which is matched with the outer nut (10).

3. The blood aspiration device of claim 2, wherein:

the diameter of the top of the outer nut (10), namely the diameter of the outer nut inlet (11), is larger than or equal to the outer diameter of the upper section cylinder of the mandrel (1), and the diameter of the outer nut inlet (11) is smaller than the outer diameter of the middle section cylinder of the mandrel (1).

4. The blood aspiration device of claim 2, wherein:

the core rod support is characterized by further comprising a fixing frame (16), wherein the fixing frame (16) is of a flat plate structure, and at least one core rod support inserting hole (17) is formed in the fixing frame (16);

the diameter of the plug holder insertion opening (17) is larger than or equal to the outer diameter of the lower section cylinder of the plug holder (5), and the diameter of the plug holder insertion opening (17) is smaller than the outer diameter of the outer nut (10).

5. The blood aspiration device of claim 2, wherein:

a groove is arranged on the inner wall of the lower section cylindrical cavity of the mandrel support (5), and a sealing ring (8) is arranged in the groove.

6. The blood aspiration device of claim 4, wherein: the fixing frame (16) is made of steel or aluminum.

7. The blood aspiration device of claim 2, wherein: the core rod (1), the core rod bracket (5) and the outer nut (10) are respectively made of polytetrafluoroethylene materials.