CN215075028U

CN215075028U - Biological sample cryopreserving device

Info

Publication number: CN215075028U
Application number: CN202120817616.3U
Authority: CN
Inventors: 刘志伟; 叶欣
Original assignee: Beijing Jishuitan Hospital
Current assignee: Beijing Jishuitan Hospital
Priority date: 2021-04-21
Filing date: 2021-04-21
Publication date: 2021-12-10
Anticipated expiration: 2031-04-21

Abstract

The utility model provides a biological sample cryopreserving device, include: the freezing storage device comprises a liquid nitrogen storage tank and a freezing storage carrier, wherein the freezing storage carrier is arranged in the liquid nitrogen storage tank and can be taken out from an inlet of the liquid nitrogen storage tank; the upper surface of freezing the carrier is equipped with a plurality of accepting grooves that are used for placing freezing the pipe of depositing, and the accepting groove extends along vertical direction, all is equipped with the fixing device who is used for fixed freezing the pipe of depositing in every accepting groove. The utility model provides a biological sample cryopreserving device effectively avoids the sample to contact with the external world many times.

Description

Biological sample cryopreserving device

Technical Field

Belongs to the field of medical apparatus and instruments, and mainly relates to a biological sample cryopreservation device.

Background

In medical experiments, large amounts of biological samples are required. At present, the main flow is that the obtained sample is quickly put into liquid nitrogen (tank) for temporary storage, and after all the materials are obtained, the sample is taken out for arrangement, and then the sample is put into a refrigerator at minus 80 ℃ for freezing storage, and is taken out from the refrigerator when in use. In the process of obtaining a sample, the sample is exposed to a room temperature space for many times, so that multiple freeze thawing can be caused, and the sample is easy to damage.

SUMMERY OF THE UTILITY MODEL

To the defect among the prior art, the utility model provides a biological sample freezes deposits device effectively avoids the sample to contact with the external world many times.

The utility model provides a biological sample cryopreserving device, include: the freezing storage device comprises a liquid nitrogen storage tank and a freezing storage carrier, wherein the freezing storage carrier is arranged in the liquid nitrogen storage tank and can be taken out from an inlet of the liquid nitrogen storage tank; the upper surface of freezing the carrier is equipped with a plurality of accepting grooves that are used for placing freezing the pipe of depositing, the accepting groove extends along vertical direction, every all be equipped with the fixing device who is used for fixed freezing the pipe of depositing in the accepting groove.

The utility model provides a biological sample cryopreserving device's theory of operation as follows: when the freezing storage device is used, the freezing storage tube is finally placed into the freezing storage carrier, the freezing storage carrier is placed into the liquid nitrogen storage tank for temporary storage, and after material taking is completed, the freezing storage carrier can be directly placed into a refrigerator at minus 80 ℃ for freezing storage, so that repeated freezing and thawing can be avoided when samples are sorted secondarily.

When the freezing carrier is put into liquid nitrogen, the freezing pipe is easy to float up due to the air in the freezing pipe, and the freezing pipe can be fixed in the accommodating groove through the fixing device.

According to the utility model provides an embodiment, still including being used for the setting be in the pipe is deposited to freezing in the accepting groove, the bottom of depositing the pipe is equipped with first magnet freezing, fixing device is for setting up iron plate in the accepting groove works as the pipe is deposited to freezing inserts in the accepting groove time, first magnet with the iron plate actuation.

According to the utility model provides an embodiment, still include and freeze the unit of depositing, every it can put into a plurality ofly to freeze in the deposit pipe freeze the unit of depositing, it is a plurality of freeze the unit and follow freeze the length direction who deposits the pipe and arrange, it is equipped with the label position to freeze the unit of depositing.

According to the utility model provides an embodiment, it is equipped with first guide part to freeze to deposit the pipe, it is equipped with the second guide part to freeze to deposit the unit, the second guide part can with first guide part adaptation makes the label position orientation of freezing the unit is preset's direction.

According to the utility model provides an embodiment, first guide part is for setting up cryopreserved intraduct gib block, the gib block is followed cryopreserved pipe's length direction extends, the second guide part is for setting up cryopreserved unit outside guide way.

According to the utility model provides an embodiment, the cryopreserving pipe is including dismantling body and the lid of connection.

According to the utility model provides an embodiment, the body still is equipped with the second magnet, first magnet sets up the bottom of body, the second magnet sets up with the form that can slide the inside of body, just first magnet with the one end polarity that the second magnet is close to each other is the same.

According to the utility model provides an embodiment, the entry of body is equipped with and is used for preventing the stopper that the second magnet drops.

According to the utility model provides an embodiment, the entry of body is equipped with the elastic rubber ring, the cryopreserving unit passes during the elastic rubber ring, with elastic rubber ring interference fit.

According to the utility model provides an embodiment, when freezing and depositing the unit and being located when the pipe is internal, the freezing and depositing unit that is located the top is in support under the effect of second magnet and lean on the elastic rubber ring, and its upper end is followed the center of elastic rubber ring is stretched out.

According to the utility model provides an embodiment, the cryopreserved pipe is equipped with the label position.

According to the utility model provides a pair of embodiment, liquid nitrogen storage jar is equipped with slide rail and elevating platform, the slide rail sets up along vertical direction, the elevating platform slides and sets up on the slide rail, the elevating platform is equipped with the handle.

According to the utility model provides an embodiment, the elevating platform is a plurality of, sets up along vertical direction interval on the handle.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the technical solutions in the prior art will be briefly described below. Throughout the drawings, like elements or portions are generally identified by like reference numerals. In the drawings, elements or portions are not necessarily drawn to scale.

FIG. 1 is a schematic structural diagram of a biological sample cryopreservation device according to an embodiment;

FIG. 2 is a schematic structural diagram of a cryopreservation vector;

FIG. 3 is a partial cross-sectional view of a cryopreservation carrier;

FIG. 4 is a schematic structural view of a cryopreservation tube;

FIG. 5 is a schematic structural diagram of the cryopreservation unit.

Description of the reference numerals

10-liquid nitrogen storage tank

111-slide rail

112-lifting platform

113-handle

20-cryopreservation carrier

21-holding tank

22-fixing device

30-freezing tube

31-tube body

32-cover body

331-first magnet

332-second magnet

34-elastic rubber ring

35-guide strip

40-cryopreservation unit

41-guide groove

Detailed Description

Embodiments of the present invention will be described in detail below with reference to the accompanying drawings. The following examples are only for illustrating the technical solutions of the present invention more clearly, and therefore are only examples, and the protection scope of the present invention is not limited thereby.

It is to be noted that unless otherwise specified, technical or scientific terms used herein shall have the ordinary meaning as understood by those skilled in the art to which the present invention belongs.

Examples

Referring to fig. 1 to 5, the present embodiment provides a biological sample cryopreservation apparatus including: the freezing storage device comprises a liquid nitrogen storage tank 10 and a freezing storage carrier 20, wherein the freezing storage carrier 20 is arranged in the liquid nitrogen storage tank 10 and can be taken out from the inlet of the liquid nitrogen storage tank 10; the upper surface of the freezing carrier 20 is provided with a plurality of accommodating grooves 21 for accommodating the freezing pipes 30, the accommodating grooves 21 extend along the vertical direction, and a fixing device 22 for fixing the freezing pipes 30 is arranged in each accommodating groove 21.

When the freezing storage device is used, the freezing storage tube 30 is finally placed into the freezing storage carrier 20, the freezing storage carrier 20 is placed into the liquid nitrogen storage tank 10 for temporary storage, and after material taking is completed, the freezing storage carrier 20 can be directly placed into a refrigerator at the temperature of-80 ℃ for freezing storage, so that repeated freezing and thawing caused by secondary sample arrangement is avoided.

The cryopreservation tube 30 in this embodiment is also provided with a label location. Set up the label in the label position of freezing pipe 30, the person of facilitating the use takes.

When the freezing medium 20 is put in liquid nitrogen, air is easily floated from the freezing tube 30, and the freezing tube 30 can be fixed in the storage tank 21 by the fixing means 22.

The biological sample freezing device further comprises a freezing tube 30 arranged in the accommodating groove 21, a first magnet 331 is arranged at the bottom of the freezing tube 30, the fixing device 22 is an iron block arranged in the accommodating groove 21, and when the freezing tube 30 is inserted into the accommodating groove 21, the first magnet 331 is attracted with the iron block. The magnet is fixed by the attraction of the magnet and the iron block, and the operation is convenient.

The biological sample cryopreservation device further comprises a cryopreservation unit 40, a plurality of cryopreservation units 40 can be placed in each cryopreservation tube 30, the plurality of cryopreservation units 40 are arranged along the length direction of the cryopreservation tubes 30, and the cryopreservation units 40 are provided with label positions. The stored samples can be marked at the label position, so that the samples are convenient to take.

Specifically, the cryopreservation pipe 30 is provided with a first guide portion, the cryopreservation unit 40 is provided with a second guide portion, and the second guide portion can be matched with the first guide portion to enable the label position of the cryopreservation unit 40 to face a preset direction. The collected biological samples are placed into the freezing units 40, the freezing units 40 are grouped, and a plurality of freezing units 40 in the same group are placed into the same freezing pipe 30, so that the grouping is further completed without secondary arrangement.

The first guide part is a guide bar 35 arranged inside the freezing and storing pipe 30, the guide bar 35 extends along the length direction of the freezing and storing pipe 30, and the second guide part is a guide groove 41 arranged outside the freezing and storing unit 40. When putting into and freezing the deposit unit 40, freezing the guide way 41 of deposit unit 40 and freezing the guide bar 35 adaptation in the deposit pipe 30 to the corner of depositing unit 40 is frozen in the restriction, makes freezing a plurality of label positions of depositing unit 40 in the deposit pipe 30 all towards appointed direction, and convenience of customers looks over.

Specifically, the vial 30 includes a tube body 31 and a lid body 32 that are detachably connected. In use, the cover 32 is opened to access the freezing unit 40.

The tube 31 is provided with a second magnet 332, the first magnet 331 is disposed at the bottom of the tube 31, the second magnet 332 is slidably disposed inside the tube 31, and the polarities of the ends of the first and

second magnets

331 and 332 close to each other are the same. The polarity of the end, close to each other, of the first magnet 331 and the second magnet 332 is the same, the two magnets repel each other, and the second magnet 332 is usually located at the uppermost end, so that the freezing unit 40 is pushed upwards, the freezing unit 40 is located at the upper part in the tube 31 and is sequentially abutted against each other, and the freezing unit 40 is prevented from sliding in the tube 31 and colliding with each other, so that the equipment is damaged.

Further, the inlet of the tube 31 is provided with a stopper for preventing the second magnet 332 from falling off. When the tube 31 is empty, the second magnet 332 abuts against the lower end of the stopper, preventing the second magnet 332 from coming out of the inlet of the tube 31.

In this embodiment, the elastic rubber ring 34 that above-mentioned stopper was equipped with for the entry of body 31, when the unit 40 that freezes passed elastic rubber ring 34, with elastic rubber ring 34 interference fit. The cryopreservation unit 40 located in the tube body 31 is prevented from being automatically ejected by the elastic rubber ring 34. In other embodiments, the stop and the circlip may be provided separately. In other embodiments, the limiting block and the elastic rubber ring can be arranged respectively.

More specifically, when the freezing unit 40 is located in the tube body 31, the freezing unit 40 located at the uppermost end abuts on the elastic rubber ring 34 by the second magnet 332, and the upper end thereof protrudes from the center of the elastic rubber ring 34. The freezing and storing unit 40 is in a shuttle shape, two ends of the freezing and storing unit are small, and the middle of the freezing and storing unit is thick. The rubber ring is extended from the upper end of the upper freezing unit 40, and the middle part of the upper freezing unit is abutted against the inner ring of the rubber ring, so that the inlet of the tube body 31 is sealed, the air convection between the inside and the outside of the tube body 31 is prevented, and the low-temperature state in the tube body 31 is effectively maintained.

More specifically, the liquid nitrogen storage tank 10 is provided with a slide rail 111 and a lifting platform 112, the slide rail 111 is arranged along the vertical direction, the lifting platform 112 is arranged on the slide rail 111 in a sliding manner, and the lifting platform 112 is provided with a handle 113. When the freezing storage carrier is used, the lifting platform 112 is lifted through the lifting handle 113, so that the freezing storage carrier 20 is placed on the lifting platform 112.

More specifically, the lifting platform 112 is provided in plurality and is disposed on the handle 113 at intervals in the vertical direction. A plurality of lifting platforms 112 are operated simultaneously by a handle 113.

In the description of the present application, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "horizontal", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are used only for convenience in describing the present invention and for simplicity in description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.

Furthermore, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. In the description of the present invention, "a plurality" means two or more unless specifically limited otherwise.

In the specification of the present invention, a large number of specific details are explained. It is understood, however, that embodiments of the invention may be practiced without these specific details. In some instances, well-known methods, structures and techniques have not been shown in detail in order not to obscure an understanding of this description.

In the description herein, particular features, structures, materials, or characteristics may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples and features of different embodiments or examples described in this specification can be combined and combined by one skilled in the art without contradiction.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; such modifications and substitutions do not substantially depart from the scope of the embodiments of the present invention, and are intended to be covered by the claims and the specification.

Claims

1. Biological sample cryopreserving device, its characterized in that includes: the freezing storage device comprises a liquid nitrogen storage tank (10) and a freezing carrier (20), wherein the freezing carrier (20) is arranged in the liquid nitrogen storage tank (10) and can be taken out from an inlet of the liquid nitrogen storage tank (10); the upper surface of the freezing storage carrier (20) is provided with a plurality of containing grooves (21) for containing the freezing storage tubes (30), the containing grooves (21) extend in the vertical direction, and a fixing device (22) for fixing the freezing storage tubes (30) is arranged in each containing groove (21).

2. The biological sample cryopreservation device according to claim 1, further comprising a cryopreservation tube (30) arranged in the accommodating groove (21), wherein a first magnet (331) is arranged at the bottom of the cryopreservation tube (30), the fixing device (22) is an iron block arranged in the accommodating groove (21), and when the cryopreservation tube (30) is inserted into the accommodating groove (21), the first magnet (331) is attracted with the iron block.

3. The biological sample cryopreservation device according to claim 2, further comprising a plurality of cryopreservation units (40), wherein a plurality of the cryopreservation units (40) can be placed in each of the cryopreservation tubes (30), the plurality of the cryopreservation units (40) are arranged along the length direction of the cryopreservation tubes (30), and the cryopreservation units (40) are provided with label positions.

4. The biological sample cryopreservation device of claim 3, wherein the cryopreservation tube (30) is provided with a first guide portion, and the cryopreservation unit (40) is provided with a second guide portion which can be adapted to the first guide portion so that the label position of the cryopreservation unit (40) faces a preset direction.

5. The biological sample cryopreservation device according to claim 4, wherein the first guide part is a guide bar (35) arranged inside the cryopreservation tube (30), the guide bar (35) extends along the length direction of the cryopreservation tube (30), and the second guide part is a guide groove (41) arranged outside the cryopreservation unit (40).

6. The biological sample cryopreservation device of claim 5, wherein the cryopreservation tube (30) comprises a tube body (31) and a cover body (32) which are detachably connected.

7. The biological sample cryopreservation device according to claim 6, wherein the tube body (31) is further provided with a second magnet (332), the first magnet (331) is arranged at the bottom of the tube body (31), the second magnet (332) is slidably arranged inside the tube body (31), and the polarities of the ends of the first magnet (331) and the second magnet (332) which are close to each other are the same.

8. The biological sample cryopreservation device of claim 7, wherein the inlet of the tube (31) is provided with a stopper for preventing the second magnet (332) from falling off.

9. The biological sample cryopreservation device of claim 8, wherein the inlet of the tube (31) is provided with an elastic rubber ring (34), and the cryopreservation unit (40) is in interference fit with the elastic rubber ring (34) when passing through the elastic rubber ring (34).

10. Biological sample cryopreservation device according to claim 9 characterised in that when a cryopreservation unit (40) is located inside the tube (31), the topmost cryopreservation unit (40) rests on the elastic rubber ring (34) under the action of the second magnet (332) and its upper end protrudes from the centre of the elastic rubber ring (34).