CN215020331U

CN215020331U - Nasopharyngeal cavity cooling catheter for selective brain target temperature management

Info

Publication number: CN215020331U
Application number: CN202121241139.7U
Authority: CN
Inventors: 周祥; 赵家鹏; 史进
Original assignee: Henan Sanhao Medical Technology Co ltd
Current assignee: Henan Sanhao Medical Technology Co ltd
Priority date: 2021-06-04
Filing date: 2021-06-04
Publication date: 2021-12-07
Anticipated expiration: 2031-06-04

Abstract

The utility model discloses a nasopharynx chamber cooling catheter for selectivity brain target temperature management, including two-chamber pipe, terminal sacculus and two independent branch pipe passageways each other, be connected as a whole between two-chamber pipe one end tip and the branch pipe passageway, in addition one end tip with terminal sacculus is connected as an organic wholely, and two independent branch pipe passageway tip do not are provided with the inlet opening and the apopore branch pipe passageway that are used for intaking, go out water and are equipped with physics cooling appearance outward, physics cooling appearance is used for controlling the velocity of flow and the pressure of cooling water to drive the cooling water by two-chamber pipe at cooling catheter end sacculus inner loop flow, not organize direct contact with the periphery. In this way, the utility model discloses a product is safe and effective to the patient, can improve neural prognosis and survival rate, prevents moreover with the relevant complication of whole-body cooling, can realize carrying out direct continuous cooling to the nasopharyngeal cavity, does not have the target temperature management that reduces the brain temperature and carry out the brain temperature of wound.

Description

Nasopharyngeal cavity cooling catheter for selective brain target temperature management

Technical Field

The utility model relates to a nasopharynx chamber cooling tube is used in brain target temperature management relates to the medical treatment field, especially relates to a nasopharynx chamber cooling tube for selective brain target temperature management.

Background

Acute brain injury caused by craniocerebral trauma, stroke, cerebral ischemia secondary to cardiac arrest, causes millions of people worldwide to become disabled and die each year. For patients with severe brain injury, cooling of the brain is a promising treatment. At present, the whole body cooling is mostly adopted, and serious complications of the whole body can be caused. The utility model provides a novel method for selectively reducing brain temperature by a nasopharynx cooling catheter, which is provided by Raphael Einsteld Sim õ es Ferreia and the like in the neurology department of Saint Paul, Barwest, and is an innovation and a change on the basis.

SUMMERY OF THE UTILITY MODEL

The utility model discloses the technical problem who mainly solves provides one kind and is safe and effective to the patient, can improve neural prognosis and survival rate, prevents the nasopharynx chamber cooling catheter who is used for selectivity brain target temperature management with the relevant complication of whole body cooling moreover.

In order to solve the technical problem, the utility model discloses a technical scheme be: the utility model provides a nasopharynx chamber cooling catheter for selective brain target temperature management, include two-chamber pipe, be used for utilizing the outer end to adjust pressure and adjust the terminal sacculus and two branch pipe passageways independent each other of the expansion size of gasbag, be connected as a whole between two-chamber pipe one end tip and the branch pipe passageway, in addition one end tip with terminal sacculus is connected as an organic wholely, and two branch pipe passageway tip independent each other do not are provided with inlet opening and the apopore that is used for intaking, goes out water, two-chamber pipe are equipped with physics cooling appearance outside the junction of two branch pipe passageways independent each other, physics cooling appearance is used for controlling the velocity of flow and the pressure of cooling water to drive cooling water is by two-chamber pipe at cooling pipe end sacculus inner loop flow, not with peripheral tissue direct contact.

In a preferred embodiment, the branch pipe channels of the two branch pipe channels which are independent of each other are a water injection channel and a water outlet channel respectively, and the water injection channel and the water outlet channel are connected with the double-cavity catheter in a Y shape.

In a preferred embodiment, a connecting part is arranged at the connecting part of the water injection cavity, the water outlet cavity and the double-cavity catheter, and the connecting part is electrically connected with the physical cooling instrument.

In a preferred embodiment, the water injection cavity channel is provided with a water inlet hole for communicating with the tail end saccule, the end part of the water inlet hole is provided with a water inlet joint, and a water inlet hole control valve is arranged at the position, close to the water inlet hole, of the water injection cavity channel of the double-cavity catheter, of the water inlet hole.

In a preferred embodiment, the water outlet channel is provided with a water outlet hole communicated with the tail end balloon, the end part of the water outlet hole is provided with a water outlet joint, and a water outlet hole control valve is arranged at a position, close to the water outlet hole, on the water outlet channel of the double-cavity catheter, where the water outlet hole leads to the water outlet hole.

In a preferred embodiment, the water outlet is located at a distal end of the water inlet.

In a preferred embodiment, the physical cooling instrument is continuously cycled pressurized.

In a preferred embodiment, the cooling rate of the physical cooling instrument is less than or equal to 2 ℃/min, and the temperature change is less than or equal to 0.1 ℃.

In a preferred embodiment, the physical cooling instrument has a cold compress temperature range of: 5-40 ℃.

In a preferred embodiment, the body temperature display measuring temperature range of the physical cooling instrument is as follows: 20-45 ℃.

The utility model has the advantages that: is safe and effective for patients, can improve the neural prognosis and the survival rate, prevents complications related to whole body cooling, and can realize direct and continuous cooling of the nasopharyngeal cavity and noninvasive brain temperature reduction for the target temperature management of brain temperature.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained without inventive work, wherein:

FIG. 1 is a block diagram of one embodiment of a nasopharyngeal cavity cooling catheter for selective brain target temperature management of the present invention;

the reference numbers in the drawings are as follows: 1. a double lumen catheter; 2. a water injection cavity channel; 201. a water inlet hole; 202. a water inlet hole control valve; 203. a water inlet joint; 3. a water outlet cavity channel; 301. a water outlet hole; 302. a water outlet hole control valve; 303. a water outlet joint; 4. a connecting site; 5. a physical cooling instrument; 6. a tip balloon.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely below, and it should be apparent that the described embodiments are only some embodiments of the present invention, but not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.

Referring to fig. 1, in an embodiment of the present invention, a nasopharyngeal cavity cooling catheter for selective brain target temperature management is provided, said nasopharyngeal cavity cooling catheter for selective brain target temperature management comprising the following embodiments.

Example 1

The utility model provides a nasopharyngeal cavity cooling catheter for selective brain target temperature management, includes two-chamber pipe 1, is used for utilizing the outer end to adjust pressure and adjusts the terminal sacculus 6 and two branch pipe ways independent each other of the expansion size of gasbag, be connected as a whole between 1 one end tip of two-chamber pipe and the branch pipe way, in addition one end tip with terminal sacculus 6 is connected as an organic wholely, and two branch pipe way tip independent each other are provided with inlet opening 201 and apopore 301 that are used for into water, play water respectively, two-chamber pipe 1 are equipped with physics cooling appearance 5 with the junction of two branch pipe ways independent each other outward, physics cooling appearance 5 is used for controlling the velocity of flow and the pressure of cooling water to the drive cooling water is by two-chamber pipe 1 at cooling pipe end sacculus inner loop flow, not with peripheral tissue direct contact.

The branch pipe channels of the two branch pipe channels which are independent of each other are a water injection channel 2 and a water outlet channel 3 respectively, and the water injection channel 2 and the water outlet channel 3 are connected with the double-cavity catheter 1 to form a Y shape.

The connection parts 4 are arranged at the connection parts of the water injection cavity 2, the water outlet cavity 3 and the double-cavity catheter 1, and the connection parts 4 are electrically connected with the physical cooling instrument 5.

The water injection cavity 2 is provided with a water inlet 201 for communicating with the tail end balloon 6, the end part of the water inlet 201 is provided with a water inlet joint 203, and the part of the water inlet 201, which is close to the water inlet 201, of the water injection cavity 2, which leads to the double-cavity catheter 1, is provided with a water inlet control valve 202.

The water outlet channel 3 is provided with a water outlet 301 communicated with the tail end balloon 6, the end of the water outlet 301 is provided with a water outlet joint 303, a position, close to the water outlet 301, of the water outlet channel 3, where the water outlet 301 leads to the double-cavity catheter 1, is provided with a water outlet control valve 302, and the water outlet 301 is located at the far end of the water inlet 201.

The physical cooling instrument 5 is used for continuous cyclic pressurization, the cooling rate is less than or equal to 2 ℃/min, and the temperature change is less than or equal to 0.1 ℃. Cold compress temperature range of the physical cooling instrument 5: the temperature of the body is 5-40 ℃, and the temperature display measurement range is as follows: 20-45 ℃; the physical cooling instrument 5 controls the flow rate and pressure of cooling water to drive the cooling water to circularly flow in the balloon at the end of the cooling catheter through a connecting pipe without directly contacting with peripheral tissues; the cooling water circulation takes away the heat of the peripheral organ tissues of the tail end saccule 6 to reduce the temperature of the peripheral organ tissues, thereby achieving the purposes of low-temperature treatment and target temperature management. Can realize direct and continuous cooling of the nasopharyngeal cavity and noninvasive brain temperature reduction for brain temperature target temperature management.

Example 2

A nasopharynx cavity cooling catheter for selective brain target temperature management comprises a double-cavity catheter, wherein two branch catheter channels which are independent from each other are arranged in a main body of the double-cavity catheter, namely a water injection cavity channel and a water outlet cavity channel; a distal balloon disposed on the double-lumen catheter, the pressure of which can be adjusted at the outer end to adjust the size of the balloon expansion, which must be able to withstand the fatigue of its components caused by a plurality of cycles of repeated movements, such as cycles of deploying, inflating, collapsing the balloon; the water injection cavity channel is provided with a water inlet hole communicated with the balloon, and the water outlet cavity channel is provided with a water outlet hole communicated with the balloon; the water outlet hole is positioned at the far end of the water inlet hole, and the water injection cavity channel and the water outlet cavity channel at the tail end of the balloon cooling catheter main body are joints and can be connected with a physical cooling instrument through a connecting pipe. The physical cooling instrument controls the flow rate and pressure of cooling water, drives the cooling water to circularly flow in the balloon at the end of the cooling catheter through the connecting pipe and is not directly contacted with peripheral tissues; the cooling water circulation takes away the heat of the surrounding organs of the saccule to reduce the temperature of the surrounding organs, thereby achieving the purposes of low-temperature treatment and target temperature management. Can realize direct and continuous cooling of the nasopharyngeal cavity and noninvasive brain temperature reduction for brain temperature target temperature management.

The physical cooling instrument described in the above embodiment is an existing product, wherein the physical cooling instrument adopts a full-automatic semiconductor temperature control and full-automatic pulsating pressure technology, and through a modular design, the temperature can be accurately and rapidly controlled and set, and the blood circulation can be promoted by applying pressure at the same time, and then the water bag cooling of the TPU polyurethane material with fast temperature conduction, comfortable heat preservation and good biocompatibility is combined. The physical cooling instrument can contract local blood vessels and slow down blood, reduce the permeability of capillary vessels, reduce the extravasation of interstitial fluid and slow down local metabolism, effectively reduce the release of inflammatory mediators, reduce the temperature of local tissues, contract blood vessels, reduce subcutaneous tissues, relieve tissue swelling, reduce the excitability of nerve endings, improve the pain threshold value and achieve the effects of relieving pain and swelling by cold compress treatment. The working mode of the physical cooling instrument adopts continuous and intermittent working modes, the using voltage is 220V +/-22V AC, the power frequency is 50Hz +/-1 Hz, the physical cooling instrument adopts continuous cyclic pressurization, the cooling rate is less than or equal to 2 ℃/min, the temperature change is less than or equal to 0.1 ℃, and the prior art can meet the requirement or meet the requirement of the physical cooling instrument with the parameter in the range. In the specific implementation process, the timing working time of the water pump is as follows: (a) cycle time: 13 s; (b) batch time: 52 s; (c) initial batch time: for 90 s.

In a particular study, patients were randomized and the study was between 18 and 80 years of age, regardless of sex, and the results showed that all patients enrolled had a mean reduction in brain temperature of 2 ℃ or more, from baseline values of 2.5 ± 0.9 ℃ (P = 0.04) in terms of therapeutic efficacy. At baseline, mean body temperature 37.3 ± 1.1 ℃, duration of intervention 36.0 ± 0.8 ℃; brain temperature averaged-1.2 ± 0.8 ℃ (P = 0.04) with body temperature difference during intervention. In terms of safety, nasopharyngeal cavity cooling catheters using the selective brain target temperature management of our study were well tolerated for intervention, no significant changes in hemodynamic parameters were seen, and no relevant changes in intracranial pressure and transcranial doppler ultrasound (TCD) measurements were observed. Blood removal K⁺Laboratory test results were not significantly altered except for levels and blood counts. Blood K⁺The levels varied significantly (P = 0.04), but all were within the normal range.

Therefore, the utility model has the advantages of it is following: is safe and effective for patients, can improve the neural prognosis and the survival rate, prevents complications related to whole body cooling, and can realize direct and continuous cooling of the nasopharyngeal cavity and noninvasive brain temperature reduction for the target temperature management of brain temperature.

The above only is the embodiment of the present invention, not limiting the patent scope of the present invention, all of which utilize the equivalent structure or equivalent flow transformation made by the content of the specification of the present invention, or directly or indirectly applied to other related technical fields, all included in the same way in the patent protection scope of the present invention.

Claims

1. The nasopharynx cavity cooling catheter for selective brain target temperature management is characterized by comprising a double-cavity catheter (1), a tail end balloon (6) and two mutually independent branch catheter channels, wherein the tail end balloon (6) is used for adjusting the expansion size of a balloon by utilizing the outer end to adjust pressure, one end part of the double-cavity catheter (1) is connected with the branch catheter channels into a whole, the other end part of the double-cavity catheter is connected with the tail end balloon (6) into a whole, the end parts of the two mutually independent branch catheter channels are respectively provided with a water inlet hole (201) and a water outlet hole (301) for water inlet and outlet, a physical cooling instrument (5) is arranged outside the joint of the double-cavity catheter (1) and the two mutually independent branch catheter channels, the physical cooling instrument (5) is used for controlling the flow rate and the pressure of cooling water so as to drive the cooling water to circularly flow in the balloon at the cooling catheter end by the double-cavity catheter (1), without direct contact with surrounding tissue.

2. The nasopharyngeal cavity cooling catheter for selective brain target temperature management according to claim 1, wherein the branch channels of two branch channels independent of each other are water injection channel (2) and water outlet channel (3), respectively, and the water injection channel (2) and the water outlet channel (3) are connected with the double-lumen catheter (1) in a "Y" shape.

3. The nasopharyngeal cavity cooling catheter for selective brain target temperature management according to claim 2, wherein a connection part (4) is provided at the connection of the water injection cavity (2), the water outlet cavity (3) and the double-cavity catheter (1), and the connection part (4) is electrically connected with the physical cooling instrument (5).

4. The nasopharynx cavity cooling catheter for selective brain target temperature management according to claim 2, wherein the water injection cavity channel (2) is provided with a water inlet hole (201) for communicating with the tail end balloon (6), the end of the water inlet hole (201) is provided with a water inlet joint (203), and a water inlet hole control valve (202) is arranged at a position, close to the water inlet hole (201), on the water injection cavity channel (2) of the double-cavity catheter (1) where the water inlet hole (201) leads to.

5. The nasopharyngeal cavity cooling catheter for selective brain target temperature management according to claim 2, wherein the water outlet cavity channel (3) is opened with a water outlet hole (301) for communicating with the distal balloon (6), the end of the water outlet hole (301) is provided with a water outlet joint (303), and a position on the water outlet cavity channel (3) of the double-cavity catheter (1) from which the water outlet hole (301) leads to the water outlet hole (301) is provided with a water outlet hole control valve (302).

6. The nasopharyngeal cavity cooling catheter for selective brain target temperature management according to claim 4 or 5, wherein the water outlet hole (301) is located distal to the water inlet hole (201).

7. Nasopharyngeal cavity cooling catheter for selective brain target temperature management according to claim 1, wherein the physical thermometer (5) is continuous cycle pressurized.

8. Nasopharyngeal cavity cooling catheter for selective brain target temperature management according to claim 1, wherein the cooling rate of the physical cooling device (5) is ≤ 2 ℃/min and the temperature variation is ≤ 0.1 ℃.

9. Nasopharyngeal cavity cooling catheter for selective brain target temperature management according to claim 1, wherein the physical thermometer (5) has a cold compress temperature range of: 5-40 ℃.

10. The nasopharyngeal cavity cooling catheter for selective brain target temperature management according to claim 1, wherein the body temperature display measurement temperature range of the physical thermometer (5) is: 20-45 ℃.