CN112244994A

CN112244994A - Radio frequency ablation catheter with cooling function and intravascular interventional therapy system

Info

Publication number: CN112244994A
Application number: CN202011257354.6A
Authority: CN
Inventors: 贺涛; 丁毅寿; 张昱昕; 蒲忠杰; 张喜博; 李向义; 陈昊; 罗延丰
Original assignee: Lepu Medical Technology Beijing Co Ltd
Current assignee: Lepu Medical Technology Beijing Co Ltd
Priority date: 2020-11-11
Filing date: 2020-11-11
Publication date: 2021-01-22

Abstract

The invention discloses a radio frequency ablation catheter with a cooling function and an intravascular interventional therapy system, wherein the radio frequency ablation catheter comprises a control handle and a catheter main body, the near end of the catheter main body is connected to the control handle, an ablation electrode is arranged at the far end of the catheter main body, a lead cavity and a cooling water cavity are arranged in the catheter main body, an ablation plug used for being connected with ablation equipment and a perfusion connector used for being connected with perfusion equipment are arranged on the control handle, and an electrode lead connected with the ablation electrode is connected to the ablation plug through the lead cavity; the cooling water cavity is communicated with the filling joint through a control handle. By radiofrequency ablation, closed surgery of the target vein can be achieved. Through set up the cooling water chamber that sets up along catheter body axial in catheter body, the coolant liquid in the cooling water chamber can cool down ablation electrode, reduces the probability that ablation electrode surface scab takes out, reduces the number of times that the catheter body took out and wipe scab among the operation process to shorten operation time, improve work efficiency.

Description

Radio frequency ablation catheter with cooling function and intravascular interventional therapy system

Technical Field

The invention relates to the technical field of medical equipment, in particular to a radio frequency ablation catheter with a cooling function and an intravascular interventional therapy system.

Background

Veins are the conduits for blood to flow back to the heart, and varicose veins refer to the tortuosity and expansion of veins caused by blood stasis, weak vein walls and other factors, and cause problems in the process of blood backflow.

The most common site of varicose veins is in the lower extremities. The varicose vein of lower limb has the treatment methods of wearing elastic socks, injecting hardener, removing operation and the like, and the deep venous valve has incomplete function and can be used for valve repair operation, endoscopic traffic branch ligation and the like. Varicose veins of lower limbs can also indicate the existence of other diseases, and the primary disease needs to be actively treated; if the deep vein is not smooth, the surgery should be more cautious to treat the superficial vein.

The denudation is too traumatic, requires multiple openings in the leg, and causes significant damage to the tissue surrounding the vein when the vein is denuded. The elastic socks belong to auxiliary treatment, and are used for varicose veins at the early stage or used for health care treatment after exfoliation or other operations.

At present, radio frequency, laser, sclerosing agent and other operation modes appear in the international market, and the method belongs to a minimally invasive technology. Small wound in operation, quick recovery after operation, good effect and the like. The intravenous radio frequency closing technology is the first choice scheme of the treatment of the lower limb varicose vein, develops a high-efficiency, stable and reliable intravascular interventional treatment system, and has very important significance for the treatment of the lower limb varicose vein.

Disclosure of Invention

Therefore, the invention provides a radio frequency ablation catheter with a cooling function and an intravascular interventional therapy system, which are used for the intracavity closure operation of vein vessels. In the operation process, firstly, a puncture point is selected near the knee of the lower limb of a human body by using a puncture needle and punctures the great saphenous vein, then a puncture sheath is arranged, the catheter is conveyed to the junction of the femoral saphenous vein in the blood vessel along the puncture sheath, the catheter is connected with a radio frequency device and a cooling water perfusion device, the target blood vessel is subjected to thermal ablation treatment by releasing radio frequency energy, so that the blood vessel is closed, and the perfusion device can continuously or intermittently input cooling liquid into the catheter in the ablation process so as to reduce the possibility of scabbing on the surface of an electrode.

In order to solve the technical problems, the technical scheme of the invention is as follows:

a radio frequency ablation catheter with a cooling function comprises a control handle and a catheter main body, wherein the catheter main body comprises a near end and a far end, the near end of the catheter main body is connected to the control handle, an ablation electrode is arranged at the far end of the catheter main body, a lead cavity and a cooling water cavity are arranged in the catheter main body, an ablation plug used for being connected with ablation equipment and a perfusion connector used for being connected with perfusion equipment are arranged on the control handle, and an electrode lead connected with the ablation electrode is connected to the ablation plug through the lead cavity; the near end of the cooling water cavity is communicated with the perfusion joint through the control handle, and the far end of the cooling water cavity extends into the pipe section of the catheter main body, wherein the pipe section is provided with the ablation electrode.

Furthermore, the filling connector comprises a water inlet connector and a water outlet connector, the cooling water cavity comprises a water inlet cavity and a water outlet cavity which are communicated, the water inlet end of the water inlet cavity is communicated with the water inlet connector, and the water inlet end of the water outlet cavity is communicated with the water outlet connector; the water inlet connector, the water inlet cavity, the water outlet cavity, the water inlet connector and the filling equipment form a cooling liquid circulation loop.

Furthermore, the ablation electrode is a section of round tube on the catheter main body, a perfusion micropore communicated with the cooling water cavity is arranged on the ablation electrode, and cooling liquid in the cooling water cavity can be sprayed out through the perfusion micropore.

Further, the ablation electrode comprises at least one negative electrode and at least two positive electrodes, and any one negative electrode is positioned between two adjacent positive electrodes; gaps are reserved between the adjacent positive electrodes and the adjacent negative electrodes, and each electrode is connected with an electrode lead.

Further, the far end of the catheter main body is provided with one or more temperature sensors used for monitoring the working temperature of the ablation electrode, and a lead connected with the temperature sensors is connected to the ablation plug through the lead cavity.

Furthermore, a lead cavity, a water inlet cavity and a water outlet cavity are arranged in the catheter main body; the lead wire cavity is used for the electrode lead wire and the temperature sensor to connect the passing through of lead wire, the cross-section in lead wire cavity is the thick appearance in middle of both ends, the intake antrum with go out the water cavity and be located respectively the relative both sides of the thin part in middle of the lead wire cavity.

Furthermore, a guide wire cavity for a guide wire to pass through is also arranged in the catheter body.

Furthermore, a guide wire cavity, two lead wire cavities, a water inlet cavity and a water outlet cavity are arranged in the catheter main body; the lead cavity is used for the electrode lead and the temperature sensor connecting lead to pass through, and the guide wire cavity is used for the guide wire to pass through; the guide wire cavity is positioned in the middle of the catheter main body; the water inlet chamber go out the water cavity, two lead wire chamber encircles and arranges the periphery in guide wire chamber, two lead wire chamber symmetry sets up the relative both sides in guide wire chamber, the water inlet chamber with it sets up to go out the water cavity symmetry lead wire chamber other relative both sides.

Further, the catheter body comprises an outer tube, an inner tube, and a water tube; the outer tube is used for providing support and the cover is established the periphery of inner tube, the inner chamber of inner tube is the seal wire chamber, the outer tube in with cavity between the inner tube outside does lead the wire chamber, the water pipe sets up in the lead wire chamber, the inner chamber of water pipe is the cooling water chamber.

Further, the ablation electrode, the outer tube and the water tube are all fixed on the inner tube in an adhesive mode.

Further, the front end of the catheter main body is a tip structure with a bend or a flexible guide wire or a guide wire cavity, or the front end of the catheter main body is a section of spring hose; the spring hose and the tip structure are used to guide the orientation of the catheter body.

In another aspect, the invention further provides an intravascular interventional therapy system with a cooling function, which comprises a radio frequency device, a perfusion device and the radio frequency ablation catheter with the cooling function, wherein the radio frequency device is connected with the ablation plug of the control handle on the radio frequency ablation catheter, and the perfusion device is connected with the perfusion connector of the control handle on the radio frequency ablation catheter.

The technical scheme of the invention has the following advantages:

1. according to the radio frequency ablation catheter with the cooling function, in the operation process, the radio frequency ablation catheter is conveyed to the junction of the saphenous vein in the blood vessel, the control handle of the radio frequency ablation catheter is connected with the radio frequency equipment and the perfusion equipment, and the ablation electrode conducts heat ablation treatment on the target blood vessel by releasing radio frequency energy after the radio frequency equipment is connected with the ablation electrode, so that the blood vessel is closed. The perfusion device can continuously or intermittently inject cooling liquid into the cooling water cavity in the catheter main body, and the temperature of the surface of the ablation electrode can be reduced by the cooling liquid passing through the cooling water cavity, so that the probability of scabbing on the surface of the ablation electrode in the operation process is reduced, the frequency of taking out the radio frequency ablation catheter to wipe the scabbing in the operation process is reduced, the operation time is shortened, and the working efficiency is improved.

2. According to the radio frequency ablation catheter with the cooling function, after the water inlet connector and the water outlet connector on the control handle are connected with the perfusion device, the perfusion device can continuously or intermittently input cooling liquid into the water inlet cavity in the ablation process, the cooling liquid can be recycled in the cooling liquid circulation loop, and compared with a mode that the cooling liquid is sprayed out through micropores perfused on the ablation electrode, the radio frequency ablation catheter with the cooling function can reduce the influence of the cooling liquid entering a blood vessel on a human body on the premise of effectively reducing the surface temperature of the ablation electrode, and is convenient to control the cooling rate of the ablation electrode by controlling the flow rate in the cooling liquid circulation loop.

3. According to the radiofrequency ablation catheter with the cooling function, the perfusion micropores are formed in the wall of the ablation electrode, cooling liquid in the cooling water cavity can be sprayed out through the perfusion micropores, the temperature of blood in a blood vessel near the ablation electrode can be reduced, the blood concentration can be diluted, ions in the blood are effectively prevented from scabbing on the surface of the ablation electrode to influence the normal work of the ablation electrode, and therefore the effectiveness and the safety of ablation are improved.

4. According to the radiofrequency ablation catheter with the cooling function, the temperature sensor at the far end of the catheter main body can monitor the working temperature of the ablation electrode, and the output power of radiofrequency equipment and the flow of cooling liquid output by perfusion equipment can be conveniently controlled according to the detected temperature monitoring signal.

5. According to the radio frequency ablation catheter with the cooling function, the section of the lead cavity is in the shape of thick two ends and thin middle, the water inlet cavity and the water outlet cavity are respectively positioned on the two opposite sides of the thin middle part of the lead cavity, the catheter main body with the structural layout is simple in structure and compact in layout, the internal space of the catheter main body can be fully utilized, electrode leads connected with a plurality of electrodes can be wired in the same lead cavity, and cooling liquid in the water inlet cavity and the water outlet cavity can better play a role in taking away heat of the ablation electrodes.

6. According to the radio frequency ablation catheter with the cooling function, the guide wire cavity is arranged in the middle of the catheter main body, and the water inlet cavity, the water outlet cavity and the two lead wire cavities are arranged on the periphery of the guide wire cavity in a surrounding mode; the catheter main body with the structural layout is compact in layout, the internal space of the catheter main body can be fully utilized, the electrode leads of the positive electrode and the negative electrode can be wired in different lead cavities, interference between the electrode leads is reduced, and cooling liquid in the water inlet cavity and the water outlet cavity can better play a role in taking away heat of the ablation electrode.

7. The invention provides a radio frequency ablation catheter with a cooling function.A catheter main body adopts an outer pipe to sleeve an inner pipe, a water pipe is arranged in a gap between the inner pipe and the outer pipe, the inner cavity of the inner pipe is used as a guide wire cavity, the cavity between the inner part of the outer pipe and the outer part of the inner pipe is used as a lead wire cavity, and the inner cavity of the water pipe is used as a cooling water cavity; the catheter main body with the structural design adopts the structure that the inner tube and the water tube are sleeved by the outer tube, and compared with the mode that the guide wire cavity, the cooling water cavity and the lead cavity are directly arranged on the catheter main body, the catheter main body with the structural design is simpler to manufacture.

8. According to the intravascular interventional treatment system with the cooling function, in the operation process, the radio frequency ablation catheter is conveyed to the junction of the saphenous femoris vein in the blood vessel, and the radio frequency device releases radio frequency energy through the ablation electrode on the catheter main body to perform thermal ablation treatment on a target blood vessel, so that the blood vessel is closed; the perfusion device can continuously or intermittently inject cooling liquid into the cooling water cavity in the catheter main body, and the temperature of the surface of the ablation electrode can be reduced by the cooling liquid passing through the cooling water cavity, so that the probability of scabbing on the surface of the ablation electrode in the operation process is reduced, the frequency of taking out the radio frequency ablation catheter to wipe the scabbing in the operation process is reduced, the operation time is shortened, and the working efficiency is improved.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.

FIG. 1 is a schematic diagram of an endovascular interventional therapy system with cooling in an embodiment of the present invention;

FIG. 2 is a schematic structural view of a radio frequency ablation catheter in an embodiment of the invention;

FIG. 3 is a schematic view of a first cross-sectional configuration of the distal end of a radio frequency ablation catheter in an embodiment of the invention;

FIG. 4 is a schematic view of a second cross-sectional configuration of the distal end of the RF ablation catheter in accordance with an embodiment of the invention;

FIG. 5 is a cross-sectional view of a first catheter body in an embodiment of the invention;

FIG. 6 is a cross-sectional view of a second catheter body in an embodiment of the invention;

FIG. 7 is a cross-sectional view of a third catheter body in an embodiment of the invention;

FIG. 8 is a schematic view of a first catheter tip according to an embodiment of the present invention;

FIG. 9 is a schematic view of a second catheter tip according to an embodiment of the present invention;

FIG. 10 is a schematic view of a third catheter tip according to an embodiment of the present invention;

FIG. 11 is a schematic view of a fourth catheter tip according to an embodiment of the present invention;

FIG. 12 is a schematic view of the distribution of ablation electrodes on the catheter body in an embodiment of the present invention, wherein neither the positive electrode nor the negative electrode has perfusion micropores;

FIG. 13 is a schematic view of the arrangement of the ablation electrodes on the catheter body according to the embodiment of the present invention, wherein the negative electrode is provided with perfusion micropores, and the positive electrode is not provided with perfusion micropores;

FIG. 14 is a schematic view showing the arrangement of ablation electrodes on the catheter body according to the embodiment of the present invention, wherein perfusion micropores are formed on the positive electrode and the negative electrode;

fig. 15 is a schematic view of an application scenario of the rf ablation catheter of the endovascular interventional therapy system with cooling function in the embodiment of the present invention when being delivered into a target vein.

Description of reference numerals: 1. a radiofrequency ablation catheter; 2. a radio frequency device; 3. a perfusion apparatus; 31. a perfusion pump; 32. a filling pipeline; 11. a catheter body; 111. a lead cavity; 112. a water inlet cavity; 113. a water outlet cavity; 114. a guidewire lumen; 12. an ablation electrode; 121. a positive electrode; 122. a negative electrode; 13. a catheter tip; 14. a control handle; 141. a water inlet joint; 142. an ablation joint; 143. a water outlet joint; 144. a handle body; 15. a temperature sensor; 16. an electrode lead; 11.1, an outer tube; 11.2, an inner tube; 11.3, a water pipe; 11.4, spacer ring.

Detailed Description

The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it should be understood that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.

In addition, the technical features involved in the different embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.

An endovascular interventional therapy system with cooling function, as shown in fig. 1, is composed of a radiofrequency ablation catheter 1, a radiofrequency device 2 and an infusion device 3. The perfusion device 3 comprises a perfusion pump 31 and a perfusion pipeline 32, and the radio frequency device 2 comprises a connection module, a control module, a temperature module and a power output module.

As shown in fig. 2, the radio frequency ablation catheter 1 includes a control handle 14 and a catheter body 11. The catheter main body 11 comprises a proximal end and a distal end, the proximal end of the catheter main body 11 is connected to the control handle 14, the distal end of the catheter main body 11 is provided with a catheter tip 13, and the part of the catheter main body 11 close to the catheter tip 13 is provided with an ablation electrode 12. The catheter main body 11 is provided therein with a lead wire lumen 111 and a cooling water lumen (see fig. 3 or fig. 4). The control handle 14 comprises a handle body 144, and an ablation plug, a water inlet connector 141 and a water outlet connector 143 which are connected to the handle body 144. The ablation plug is used for being electrically connected with a connecting module of the ablation device; the water inlet connector 141 and the water outlet connector 143 are used for communicating with the perfusion line 32 of the perfusion apparatus 3. An electrode lead 16 to which the ablation electrode 12 is connected to an ablation plug through a lead lumen 111 (see fig. 3 or 4, respectively).

As shown in fig. 2-5, the cooling water cavity includes a water inlet cavity 112 and a water outlet cavity 113 which are communicated, the water inlet end of the water inlet cavity 112 is communicated with the water inlet joint 141 through the control handle 14, the water outlet end of the water outlet cavity 113 is communicated with the water outlet joint 143 through the control handle 14, the distal ends of the water inlet cavity 112 and the water outlet cavity 113 extend into the pipe section of the catheter main body 11 provided with the ablation electrode 12, and the water inlet joint 141, the water inlet cavity 112, the water outlet cavity 113, the water inlet joint 141 and the perfusion device form a cooling liquid circulation loop.

In the operation process, the radiofrequency ablation catheter 1 is conveyed to the junction of the saphenous femoral vein in the blood vessel, and the radiofrequency device 2 releases radiofrequency energy through the ablation electrode 12 on the catheter main body 11 to perform thermal ablation treatment on a target blood vessel, so that the blood vessel is closed. The water inlet joint 141 and the water outlet joint 143 on the control handle 14 are connected with the perfusion device 3, the perfusion device 3 can continuously or intermittently inject cooling liquid into the cooling water cavity in the catheter main body 11, the temperature of the surface of the ablation electrode 12 can be reduced by the cooling liquid passing through the cooling water cavity, so that the probability of scabbing on the surface of the ablation electrode 12 in the operation process is reduced, the times of taking out the radio frequency ablation catheter 1 to remove the scabs in the operation process is reduced, the operation time is shortened, and the working efficiency is improved. In addition, the cooling liquid can be recycled in the cooling liquid circulation loop, and compared with the mode that the cooling liquid is sprayed outwards through the micropores filled in the ablation electrode 12, on the premise of effectively reducing the surface temperature of the ablation electrode 12, the influence of the cooling liquid entering the blood vessel on the human body can be reduced, and the cooling rate of the ablation electrode can be conveniently controlled by controlling the flow speed in the cooling liquid circulation loop. In addition, because the cooling liquid does not need to enter the blood vessels of the human body, other cooling media except physiological saline can be selected as the cooling liquid, the temperature of the cooling liquid can not be limited to the normal temperature, and the cooling liquid with lower temperature can be selected to improve the cooling effect of the cooling liquid on the surface temperature of the ablation electrode 12.

In another embodiment of this embodiment, the cooling water cavity may also be the water inlet cavity 112, and the ablation electrode 12 is provided with perfusion micropores communicated with the cooling water cavity (see fig. 11 and 12). The perfusion micropores are arranged on the wall of the ablation electrode 12, and the cooling liquid in the cooling water cavity can be sprayed out through the perfusion micropores, so that the temperature of blood in a blood vessel near the ablation electrode 12 can be reduced, the blood concentration can be diluted, ions in the blood can be effectively prevented from scabbing on the surface of the ablation electrode 12 to influence the normal work of the ablation electrode 12, and the effectiveness and the safety of ablation can be improved.

As shown in fig. 3 and fig. 8-13, the ablation electrode 12 includes two sets of positive electrodes 121 and a set of negative electrodes 122, the negative electrode 122 is located between the two sets of positive electrodes 121, a gap is provided between adjacent positive electrodes 121 and negative electrodes 122, the positive electrodes 121 and the negative electrodes 122 are both a section of circular tube on the catheter main body 11, and the length of the negative electrode 122 is twice as wide as the length of the positive electrode 121. In some embodiments, adjacent positive and

negative electrodes

121, 122 may also be separated by a spacer ring 11.2. One electrode lead 16 is connected to each electrode. The distal end of the catheter body 11 is provided with one or more temperature sensors 15 for monitoring the operating temperature of the ablation electrode 12, and the lead wires to which the temperature sensors 15 are connected to the ablation plug through the lead wire lumen 111. The temperature sensor 15 at the distal end of the catheter main body 11 can monitor the working temperature of the ablation electrode 12, and the output power of the radio frequency device 2 and the flow of the cooling liquid output by the perfusion device 3 can be conveniently controlled according to the detected temperature monitoring signal.

The schematic diagram of the first embodiment of the distal portion of the radiofrequency ablation catheter 1 shown in fig. 4 differs from the first embodiment in that the ablation electrode 12 comprises three sets of positive electrodes 121 and two sets of negative electrodes 122, each negative electrode 122 being located in the middle of two adjacent sets of positive electrodes 121. The ablation electrode 12 with the structural design is beneficial to reducing the accumulation of positive ions near the single negative electrode 122, and further reducing the probability of scabbing on the surface of the negative electrode 122.

In the first embodiment of the catheter body 11 shown in fig. 5, the catheter body 11 is provided with a guidewire lumen 111, an inlet lumen 112, and an outlet lumen 113; the lead wire cavity 111 is used for the electrode lead wire 16 and the temperature sensor 15 to pass through, the cross section of the lead wire cavity 111 is in a shape with two thick ends and a thin middle, and the water inlet cavity 112 and the water outlet cavity 113 are respectively positioned at two opposite sides of the thin middle part of the lead wire cavity 111. The section of the lead cavity 111 is in the shape of thick two ends and thin middle, the water inlet cavity 112 and the water outlet cavity 113 are respectively positioned at two opposite sides of the thin middle part of the lead cavity 111, the catheter main body 11 with the structural layout has simple structure and compact layout, the internal space of the catheter main body 11 can be fully utilized, the electrode leads 16 connected with a plurality of electrodes can be wired in the same lead cavity 111, and the cooling liquid in the water inlet cavity 112 and the water outlet cavity 113 can better play a role of taking away the heat of the ablation electrode 12.

In the second embodiment of the catheter main body 11 shown in fig. 6, a guide wire cavity 114, two guide wire cavities 111, an inlet cavity 112 and an outlet cavity 113 are arranged in the catheter main body 11; the lead cavity 111 is used for the electrode lead 16 and the temperature sensor 15 to be connected with the lead to pass through, and the guide wire cavity 114 is used for the guide wire to pass through; the guidewire lumen 114 is located in the middle of the catheter body 11; the water inlet cavity 112, the water outlet cavity 113 and the two lead wire cavities 111 are arranged around the periphery of the guide wire cavity 114, the two lead wire cavities 111 are symmetrically arranged on two opposite sides of the guide wire cavity 114, and the water inlet cavity 112 and the water outlet cavity 113 are symmetrically arranged on the other two opposite sides of the lead wire cavity 111. A guide wire cavity 114 is arranged in the middle of the catheter main body 11, and the water inlet cavity 112, the water outlet cavity 113 and the two guide wire cavities 111 are arranged on the periphery of the guide wire cavity 114 in a surrounding mode; the catheter main body 11 with the structural layout is compact in layout, the internal space of the catheter main body 11 can be fully utilized, the electrode leads 16 of the positive electrode 121 and the negative electrode 122 can be routed in different lead cavities 111, interference among the electrode leads 16 is reduced, and cooling liquid in the water inlet cavity 112 and the water outlet cavity 113 can better play a role in taking away heat of the ablation electrode 12.

In a third embodiment of the catheter body 11, as shown in fig. 7, the catheter body 11 comprises an outer tube 11.1, an inner tube 11.2, a water tube 11.3 and a spacer ring 11.4 (see fig. 14); the outer tube 11.1 is used for providing support and is sleeved on the periphery of the inner tube 11.2, the inner cavity of the inner tube 11.2 is a guide wire cavity 114 allowing a guide wire to pass through, a cavity between the inside of the outer tube 11.1 and the outside of the inner tube 11.2 is a lead wire cavity 111, the water tubes 11.3 are arranged in the lead wire cavity 111, the number of the water tubes 11.3 can be one or more, the inner tube 11.2 can provide support for the water tubes 11.3, and the inner cavity of the water tubes 11.3 is a water inlet cavity 112. The spacer ring 11.4 serves to separate the positive electrode 121 and the negative electrode 122. The catheter tip 13, the positive electrode 121, the negative electrode 122, the outer tube 11.1 and the water tube 11.3 are all fixed on the inner tube 11.2 by gluing. The negative electrode 122 is provided with perfusion micropores. In an alternative embodiment, both the positive electrode 121 and the negative electrode 122 are provided with potting pores.

Fig. 8 shows a schematic view of a first catheter tip 13, and the catheter tip 13 at the distal end of the catheter body 11 has a tip structure with a curve, which can serve to guide the direction of the catheter.

Fig. 9 shows a second structure of the catheter tip 13, in which the catheter tip 13 at the distal end of the catheter body 11 is a section of spring hose, which serves to guide the direction of the catheter.

Fig. 10 is a schematic structural view of a third catheter tip 13, and the catheter tip 13 at the distal end of the catheter body 11 is a head with a smooth arc to avoid damage to the inner wall of the blood vessel.

Fig. 11 is a schematic structural view of a fourth catheter tip 13, and the catheter tip 13 at the distal end of the catheter body 11 is a head end with a guide wire lumen through which the catheter can be guided into a tortuous and complex blood vessel.

Fig. 12 is a schematic view of a first structure of the ablation electrode 12, in which the negative electrode 122 is a section of smooth-surfaced circular tube, and the material of the smooth-surfaced circular tube may be stainless steel, a nickel-titanium tube, platinum-iridium alloy, or other conductive tubes.

Fig. 13 is a schematic diagram of a second structure of the ablation electrode 12, in which the negative electrode 122 is a section of circular tube with perfusion micropores on the surface, and the catheter main body 11 can spray cooling liquid from the micropores during operation, and the material of the negative electrode can be stainless steel, nickel-titanium tube, platinum-iridium alloy or other tubes with conductive function.

Fig. 14 is a schematic view showing a third structure of the ablation electrode 12, in which the positive electrode 121 and the negative electrode 122 are both a section of circular tube with perfusion micropores on the surface, and the catheter main body 11 can spray cooling liquid from the micropores during operation, and the material of the catheter main body can be stainless steel, a nickel-titanium tube, platinum-iridium alloy or other tubes with conductive function.

Fig. 15 is a schematic view showing an application scenario of the radiofrequency ablation catheter 1 when the radiofrequency ablation catheter 1 is delivered into a target vein, in the operation process, a puncture needle is used for selecting a puncture point near the knee of the lower limb of a human body and puncturing the great saphenous vein, then a puncture sheath is arranged, the radiofrequency ablation catheter 1 is delivered to the position about 2cm below the junction of the femoral saphenous vein in the blood vessel along the puncture sheath, the radiofrequency ablation catheter 1 is connected with a radiofrequency device 2 and a cooling water perfusion device 3, and the target blood vessel is subjected to thermal ablation treatment by releasing radiofrequency energy, so that the blood vessel is closed. And judging the closing effect of the ablation vessel according to the Doppler image in the operation, withdrawing the radio frequency ablation catheter 1 after the vessel is closed, and repeating the ablation until the vessel is closed to a puncture point. The irrigation device 3 may continuously or intermittently deliver cooling fluid into the rf ablation catheter 1 during the ablation procedure to reduce the potential for scarring of the electrode surfaces.

The radiofrequency device 2 comprises a connecting module, a control module, a temperature module and a power output module, wherein the ablation connector 142 is connected with a corresponding interface of the radiofrequency ablation instrument into a whole, when the radiofrequency device 2 outputs energy, current passes through the ablation connector 142, the conductive wire reaches the ablation electrode 12, and one or more radiofrequency loops are formed between the positive electrode 121 and the negative electrode 122, so that radiofrequency energy output is realized. The temperature of the radiofrequency ablation electrode 12 is acquired through the temperature sensor 15, the temperature signal is transmitted to the radiofrequency device 2 through a lead, and the radiofrequency device 2 adjusts the implemented parameters to carry out more reasonable control.

It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications therefrom are within the scope of the invention.

Claims

1. The radio frequency ablation catheter with the cooling function is characterized by comprising a control handle (14) and a catheter main body (11), wherein the catheter main body (11) comprises a near end and a far end, the near end of the catheter main body (11) is connected to the control handle (14), an ablation electrode (12) is arranged at the far end of the catheter main body (11), a lead cavity (111) and a cooling water cavity are arranged in the catheter main body (11), an ablation plug used for being connected with ablation equipment and a perfusion connector used for being connected with perfusion equipment (3) are arranged on the control handle (14), and an electrode lead (16) connected with the ablation electrode (12) is connected to the ablation plug through the lead cavity (111); the near end of the cooling water cavity is communicated with the perfusion joint through the control handle (14), and the far end of the cooling water cavity extends into the pipe section of the catheter main body (11) provided with the ablation electrode (12).

2. The radiofrequency ablation catheter with the cooling function as claimed in claim 1, wherein the irrigation joint comprises a water inlet joint (141) and a water outlet joint (143), the cooling water cavity comprises a water inlet cavity (112) and a water outlet cavity (113) which are communicated, the water inlet end of the water inlet cavity (112) is communicated with the water inlet joint (141), and the water inlet end of the water outlet cavity (113) is communicated with the water outlet joint (143); the water inlet joint (141), the water inlet cavity (112), the water outlet cavity (113), the water inlet joint (141) and the perfusion device (3) form a cooling liquid circulation loop.

3. The radiofrequency ablation catheter with the cooling function as claimed in claim 1 or 2, wherein the ablation electrode (12) is a section of round tube on the catheter main body (11), perfusion micropores communicated with the cooling water cavity are formed in the ablation electrode (12), and the cooling liquid in the cooling water cavity can be sprayed out through the perfusion micropores.

4. The radiofrequency ablation catheter with cooling function of claim 3, wherein the ablation electrode (12) comprises at least one negative electrode (122) and at least two positive electrodes (121), any one of the negative electrodes (122) being located between two adjacent positive electrodes (121); gaps are reserved between the adjacent positive electrodes (121) and the adjacent negative electrodes (122), and each electrode is connected with an electrode lead (16).

5. The radiofrequency ablation catheter with cooling function of claim 2, wherein the distal end of the catheter body (11) is provided with one or more temperature sensors (15) for monitoring the operating temperature of the ablation electrode (12), and the lead wire connected to the temperature sensors (15) is connected to the ablation plug through the lead wire cavity (111).

6. The radiofrequency ablation catheter with the cooling function as recited in claim 5, wherein the catheter body (11) is provided with a guide wire cavity (111), an inlet water cavity (112) and an outlet water cavity (113); the lead wire cavity (111) is used for the electrode lead wire (16) and the temperature sensor (15) to connect the passing through of lead wire, the cross-section in lead wire cavity (111) is the thick appearance in middle of both ends, intake antrum (112) with go out water cavity (113) and be located respectively lead wire cavity (111) middle thin part's relative both sides.

7. The radiofrequency ablation catheter with cooling function of claim 1, wherein a guide wire cavity (114) for a guide wire to pass through is further arranged in the catheter body (11).

8. The radiofrequency ablation catheter with the cooling function as claimed in claim 5, wherein a guide wire cavity (114), two guide wire cavities (111), an inlet water cavity (112) and an outlet water cavity (113) are arranged in the catheter body (11); the lead cavity (111) is used for the electrode lead (16) and the temperature sensor (15) to be connected with the lead to pass through, and the guide wire cavity (114) is used for the guide wire to pass through; the guide wire cavity (114) is positioned in the middle of the catheter main body (11); the utility model discloses a lead wire chamber (111) is in the periphery in guide wire chamber (114), two lead wire chamber (111) symmetry sets up the relative both sides in guide wire chamber (114), intake antrum (112) go out water chamber (113), two lead wire chamber (111) encircle to be arranged lead wire chamber (114), two lead wire chamber (111) symmetry sets up lead wire chamber (111) other relative both sides.

9. The radiofrequency ablation catheter with cooling function of claim 1, characterized in that the catheter body (11) comprises an outer tube (11.1), an inner tube (11.2) and a water tube (11.3); outer tube (11.1) are used for providing support and cover and establish the periphery of inner tube (11.2), the inner chamber of inner tube (11.2) is wire guide chamber (114), outer tube (11.1) in with cavity between outer of inner tube (11.2) does lead wire chamber (111), water pipe (11.3) set up in lead wire chamber (111), the inner chamber of water pipe (11.3) is the cooling water chamber.

10. The radiofrequency ablation catheter with cooling function of claim 9, wherein the ablation electrode (12), the outer tube (11.1), and the water tube (11.3) are all adhesively fixed to the inner tube (11.2).

11. The radiofrequency ablation catheter with cooling function as claimed in claim 10, wherein the front end of the catheter body (11) is a tip structure with a bend or with a flexible guide wire or with a guide wire cavity, or the front end of the catheter body (11) is a section of spring hose; the spring hose and the tip structure are used to guide the course of the catheter body (11).

12. An endovascular intervention system with cooling function, comprising a radio frequency device (2), an infusion device (3) and a radio frequency ablation catheter with cooling function according to any one of claims 1 to 11, wherein the radio frequency device (2) is connected with an ablation plug of a control handle (14) on the radio frequency ablation catheter (1), and the infusion device (3) is connected with an infusion joint of the control handle (14) on the radio frequency ablation catheter (1).