CN214907274U

CN214907274U - Kit for collecting salivary flora

Info

Publication number: CN214907274U
Application number: CN202120050603.8U
Authority: CN
Inventors: 党旖旎; 李文洁; 董雨; 朱永亮; 张敏; 华翼飞
Original assignee: Jiangsu Province Hospital First Affiliated Hospital With Nanjing Medical University
Current assignee: Jiangsu Province Hospital First Affiliated Hospital With Nanjing Medical University
Priority date: 2021-01-10
Filing date: 2021-01-10
Publication date: 2021-11-30
Anticipated expiration: 2031-01-10

Abstract

The utility model provides a kit for collecting saliva flora, which comprises a saliva collecting device and a storage box; the saliva collecting device is arranged in the storage box; the saliva collecting device comprises a saliva collecting part, a handheld part and a sealing cover, the saliva collecting part comprises a head end and a tail end, the tail end is fixedly connected with the handheld part, and the sealing cover is detachably covered on the head end; the head end includes the scraper blade, and the rear end an organic whole of scraper blade is connected with flourishing portion, and the inside of flourishing portion is provided with the inner groovy, and the one end and the tail end an organic whole that the scraper blade was kept away from to flourishing portion are connected.

Description

Kit for collecting salivary flora

Technical Field

The utility model relates to a saliva fungus crowd detects technical field, especially relates to a kit for saliva fungus crowd gathers.

Background

Gastric cancer is one of the most common cancers in the world, but the early gastric cancer lacks specific symptoms and lacks effective diagnostic markers, so that the prognosis of the late gastric cancer diagnosis is poor. Studies have shown that dysregulation of oral microflora can be a biomarker for many diseases of the gastrointestinal system, including esophageal cancer, colorectal cancer, pancreatic cancer, inflammatory bowel disease, and cirrhosis of the liver, among others. Changes in the oral microflora are consistent with changes in the fecal microflora, and a taxonomic model of the oral swab microflora can distinguish colorectal cancer or polyp patients from controls with 53% sensitivity and 96% specificity. Another interesting finding is that the particular appearance of the tongue coating in gastric cancer patients is related to specific characteristics of the tongue bacterial flora. This indicates that saliva samples, stomach tissue samples, and stomach fluid samples may have similarities in microbial community composition and may be utilized by non-invasive diagnostic methods. Research has found that one potential mechanism leading to the development of colorectal cancer may be related to the presence of fusobacterium nucleatum, a bacterial strain commonly found in the oral cavity, which is transmitted through the blood to the colon and localizes tumor tissue in a Fap 2-dependent manner, which may contribute to the development of colorectal cancer. The possibility of the oral symbiont to migrate to other organs and participate in active carcinogenesis has been demonstrated, supporting the rationality of the underlying mechanism of gastric cancer development associated with oral symbiosis. Recent advances in detection technology have led to increased attention to changes and function of salivary flora, and have led to the discovery of a role of salivary flora in the development of gastric cancer. Therefore, by collecting and detecting saliva of a patient, the problem of poor prognosis caused by lack of effective diagnosis biomarkers for early diagnosis of gastric cancer can be solved.

In the prior art, a saliva sample is collected by mainly adopting a cotton swab to obtain oral mucosa epithelial cells or spitting saliva into a saliva collecting tube by a patient for collection; however, the saliva sample collection method in the prior art generally has the following defects: 1. the operation is inconvenient, and the saliva sample is easy to contact with the body of a worker, so that medical care personnel feel uncomfortable; 2. the sample is easily influenced by the external environment, so that the error of the detection result is large; 3. small collection amount and difficult preservation.

SUMMERY OF THE UTILITY MODEL

In view of the above problem, the utility model provides a kit for saliva flora is gathered.

In order to achieve the above purpose, the utility model adopts the following technical scheme:

a kit for saliva flora collection, comprising a saliva collection device and a storage box; the saliva collecting device is arranged in the storage box; the saliva collecting device comprises a saliva collecting part, a handheld part and a sealing cover, the saliva collecting part comprises a head end and a tail end, the tail end is fixedly connected with the handheld part, and the sealing cover is detachably covered on the head end; the head end includes the scraper blade, the rear end an organic whole of scraper blade is connected with flourishing portion, the inside of flourishing portion is provided with the inner groovy, the flourishing portion is kept away from the one end of scraper blade with tail end an organic whole is connected.

Preferably, the scraper is circular arc-shaped.

Preferably, the inner groove is circular arc-shaped.

Preferably, the inner groove comprises a first groove edge and a second groove edge, the first groove edge is integrally connected with the scraper, and the height of the second groove edge is smaller than that of the first groove edge.

Preferably, the handheld portion is transparent and hollow tubular, the tail end is hollow and is communicated with the handheld portion, a through hole is formed in the bottom of the inner groove, and the through hole is communicated with the tail end.

Preferably, the via hole is close to one side fixedly connected with honeycomb duct of tail end, the honeycomb duct is tubaeform, the honeycomb duct is located in the tail end.

Preferably, the handle portion and the tail end are detachably connected together.

Preferably, the outer side wall of the hand-held part is provided with a scale.

Preferably, the storage box comprises a box body and a box cover, a plurality of fixing grooves for placing the saliva collecting device are arranged in the box body, and the fixing grooves have the same structure as the saliva collecting device.

Preferably, the box body is filled with a first heat preservation layer, the box cover is covered with a second heat preservation layer, and hemispherical protrusions are uniformly arranged on the second heat preservation layer.

Compared with the prior art, the beneficial effects of the utility model are that: utilize saliva collection system can be simple and convenient collection patient's saliva to seal saliva and deposit in saliva collection system, so can accomplish the collection of saliva, the storage box is used for holding the saliva collection system who gathers the completion, and provide the heat preservation environment, it is dead owing to leave human oral cavity after the temperature reduction or rise to place the saliva fungus crowd part bacterium, guarantees the accuracy of chemical examination, the transfer of the saliva sample of being convenient for simultaneously. The saliva collecting device can conveniently scrape saliva on the oral cavity and the tongue and guide the saliva into the inner grooves by using the arc-shaped scraping plate, and can scrape mucus on the tongue coating, so that the aims of collecting the saliva and collecting the tongue bacteria are fulfilled; the handheld part is matched with the inner groove, so that saliva in the inner groove can be drained into the handheld part, and the centralized storage of the saliva is facilitated; the setting of honeycomb duct can be more convenient guides saliva to handheld portion in, and can gather a large amount of saliva according to the demand, can effectively prevent the saliva backward flow simultaneously when saliva collection system level is placed. In addition, operating personnel only need hold handheld portion, then with saliva collection portion probe into patient's oral cavity and can gather the saliva, can avoid polluting operator's both hands.

Drawings

Fig. 1 is a schematic diagram of the overall structure of a saliva collecting device of a kit for collecting saliva flora according to the present invention.

Fig. 2 is a side view of a saliva collecting part of a kit for collecting a saliva flora according to the present invention.

Fig. 3 is a schematic overall structure diagram of a storage box of the kit for collecting salivary flora according to the present invention.

Detailed Description

In order to further understand the objects, structures, features and functions of the present invention, the following embodiments are described in detail.

Please refer to fig. 1, fig. 2 and fig. 3 in combination, in which fig. 1 is a schematic diagram of an overall structure of a saliva collecting device of a kit for collecting saliva flora according to the present invention, fig. 2 is a side view of a saliva collecting portion of a kit for collecting saliva flora according to the present invention, and fig. 3 is a schematic diagram of an overall structure of a storage box of a kit for collecting saliva flora according to the present invention.

As shown in fig. 1, 2 and 3, a kit for collecting saliva flora according to an embodiment of the present invention includes a saliva collecting device 10 and a storage box 20; the saliva collection device 10 is housed within a storage case 20; the saliva collecting device 10 comprises a saliva collecting part 11, a handheld part 12 and a sealing cover 13, wherein the saliva collecting part 11 comprises a head end 111 and a tail end 112, the tail end 112 is fixedly connected with the handheld part 12, and the sealing cover 13 is detachably covered on the head end 111; the head end 111 comprises a scraper 113, a receiving portion 114 is integrally connected to the rear end of the scraper 113, an inner groove 115 is formed in the receiving portion 114, and one end, far away from the scraper 113, of the receiving portion 114 is integrally connected with the tail end 112.

In one embodiment, the storage case 20 is used to hold the saliva collection device 10 after collection of saliva, thereby facilitating storage and transport of saliva after collection. The saliva collection device 10 is primarily used to collect saliva directly from the mouth of a patient. Wherein, scraper blade 113 is used for scraping in the patient oral cavity to can gather the saliva of patient oral cavity, and through scraping the stimulation, be more convenient for the patient oral cavity to secrete more saliva, so produce the virtuous circle, the collection of the saliva of being more convenient for, consequently, utilize scraper blade 113 can gather the saliva of oral cavity endocrine and flow into inner groovy 115 from scraper blade 113 upper surface, realize the collection of saliva. The hand-held portion 12 is mainly used for holding by an operator, so that the saliva collecting portion 11 can be conveniently inserted into the oral cavity of a patient, and the operator can operate the saliva collecting device 10 from the outside. The sealing cover 13 is provided to be screwed to the outside of the saliva collecting part 11 after the collection of saliva is completed, and to seal the same to prevent the outflow of saliva. After the saliva is collected, the saliva is placed in the storage box 20, and then the transportation can be carried out, so that the subsequent corresponding detection for the early diagnosis of the gastric cancer is facilitated.

As shown in fig. 1, the scraper 113 is preferably arc-shaped to facilitate scraping within the mouth of the patient and to facilitate the pooling of saliva.

As shown in fig. 1 and 2, the inner groove 115 is preferably rounded to facilitate the collection of saliva to the bottom of the inner groove 115 after the saliva drains into the inner groove 115.

As shown in fig. 1 and 2, preferably, the inner groove 115 includes a first groove edge 1151 and a second groove edge 1152, the first groove edge 1151 is integrally connected to the scraper 113, and the height of the second groove edge 1152 is smaller than that of the first groove edge 1151, so that on one hand, the volume of the whole saliva collecting part 11 can be reduced, on the other hand, the scraper 113 can be conveniently scraped in the oral cavity, and the situation that the scraper 113 is hindered from moving due to the fact that the second groove edge 1152 is too high is avoided.

As shown in fig. 1 and 2, preferably, the handle 12 is transparent and hollow and tubular, the tail end 112 is hollow and is communicated with the handle 12, a through hole 1153 is provided at the bottom of the inner groove 115, the through hole 1153 is communicated with the tail end 112, and further, a scale 121 is provided on the outer side wall of the handle 12. Therefore, the whole saliva collecting device 10 except the sealing cover 13 forms a communicated structure, the accommodating space of the saliva collecting device 10 is increased, more saliva can be collected, and later-stage inspection is facilitated; the hand-held part 12 is transparent, and is matched with the scale 121 on the outer side of the hand-held part 12, so that the total quantity of the collected saliva can be observed conveniently.

As shown in fig. 1 and 2, preferably, a flow guide tube 116 is fixedly connected to a side of the through hole 1153 close to the tail end 112, the flow guide tube 116 is in a horn shape, the flow guide tube 116 is located in the tail end 112, and the flow guide tube 116 is arranged to, on one hand, facilitate guiding saliva in the inner groove 115 into the handheld portion 12, and simultaneously prevent backflow of saliva and keep the sealing cover 13 clean when the saliva collecting device 10 is lying horizontally.

As shown in fig. 1, preferably, the handheld portion 12 is detachably connected to the tail end 112, so that the saliva collecting device 10 is directly erected when testing the saliva, and then the handheld portion 12 is unscrewed, so that the saliva can be taken out, which is simple and convenient, and is not easy to pollute the environment.

As shown in fig. 3, preferably, the storage box 20 comprises a box body 21 and a box cover 22, a plurality of fixing grooves 23 for placing the saliva collecting device 10 are arranged in the box body 21, and the structure of the fixing grooves 23 is the same as the external structure of the saliva collecting device 10. The setting of fixed slot 23 can be convenient for saliva collection device 10 fixed, avoids rocking, sets up a plurality of fixed slots 23 simultaneously, can be convenient for hold a plurality of saliva specimens, only needs to paste the label that corresponds the patient on handheld portion 12 and can distinguish, so be convenient for shift in batches and chemical examination, save time.

As shown in fig. 3, preferably, the box body 21 is filled with a first insulating layer 24, the box cover 22 is covered with a second insulating layer 25, and hemispherical protrusions 26 are uniformly arranged on the second insulating layer 25. Be provided with the heat preservation in the storage box 20, be convenient for keep warm to the saliva sample, avoid the high temperature or low leading to the interior part bacterium of saliva fungus crowd because leave the oral cavity after the high temperature or low death of temperature to can avoid influencing the testing result. The hemispherical protrusions 26 are provided on the second insulating layer 25 so as to communicate the space inside the storage box 20 and to make the temperature inside the box uniform.

The utility model discloses when specifically using, at first saliva collection system 10 is the sterile equipment that disinfects, then open sealed lid 13, hold handheld portion 12 with the hand, visit saliva collection portion 11 in the patient's mouth, then cut the rubbing of scraping in the patient's oral cavity with scraper blade 113, collect saliva on the one hand, stimulate the patient's oral cavity on the one hand, promote salivary secretion, thereby secrete more saliva, then scrape scraper blade 113 and get the saliva, and push down handheld portion 12, thereby drain the saliva from scraper blade 113 to inner groovy 115 in, then the saliva flows into via hole 1153 department along inner groovy 115 lateral wall, and in honeycomb duct 116 drains handheld portion 12, the continuous cycle operation, until gathering the saliva of corresponding volume. Then the sealing cover 13 is tightly covered, the saliva collecting device 10 is embedded in the fixing groove 23, and the box cover 22 is tightly covered, so that the saliva collecting device 10 can be stored and transported in a heat preservation way. After transferring to the inspection administrative or technical offices, open storage box 20, take out saliva collection device 10, vertical placing waits that saliva deposit unscrews the connection between tail end 112 and the handheld portion 12 behind the handheld portion 12 bottom, can make handheld portion 12 convert the test tube of a splendid attire saliva into, so be convenient for the saliva take out, also be convenient for the assay in saliva later stage.

From top to the utility model discloses a kit for saliva fungus crowd gathers, utilize saliva collection device can be simple and convenient collection patient's saliva to seal saliva and keep in saliva collection device, so can accomplish the collection of saliva, the storage box is used for holding the saliva collection device who gathers the completion, and provide the heat preservation environment, it is dead owing to leave human oral cavity after-temperature reduction or rising to place the part bacterium in the saliva fungus crowd, guarantee the accuracy of chemical examination, the transfer of the saliva sample of being convenient for simultaneously. The saliva collecting device can conveniently scrape saliva on the oral cavity and the tongue and guide the saliva into the inner grooves by using the arc-shaped scraping plate, and can scrape mucus on the tongue coating, so that the aims of collecting the saliva and collecting the tongue bacteria are fulfilled; the handheld part is matched with the inner groove, so that saliva in the inner groove can be drained into the handheld part, and the centralized storage of the saliva is facilitated; the setting of honeycomb duct can be more convenient guides saliva to handheld portion in, and can gather a large amount of saliva according to the demand, can effectively prevent the saliva backward flow simultaneously when saliva collection system level is placed. In addition, operating personnel only need hold handheld portion, then with saliva collection portion probe into patient's oral cavity and can gather the saliva, can avoid polluting operator's both hands.

The present invention has been described in relation to the above embodiments, which are only examples for implementing the present invention. It should be noted that the disclosed embodiments do not limit the scope of the invention. On the contrary, all changes and modifications which do not depart from the spirit and scope of the present invention are deemed to fall within the scope of the present invention.

Claims

1. A kit for salivary flora collection, comprising: comprises a saliva collecting device and a storage box; the saliva collecting device is arranged in the storage box;

the saliva collecting device comprises a saliva collecting part, a handheld part and a sealing cover, the saliva collecting part comprises a head end and a tail end, the tail end is fixedly connected with the handheld part, and the sealing cover is detachably covered on the head end;

the head end includes the scraper blade, the rear end an organic whole of scraper blade is connected with flourishing portion, the inside of flourishing portion is provided with the inner groovy, the flourishing portion is kept away from the one end of scraper blade with tail end an organic whole is connected.

2. Kit for collection of salivary flora according to claim 1, wherein: the scraper blade is arc-shaped.

3. Kit for collection of salivary flora according to claim 2, characterized in that: the inner groove is arc-shaped.

4. Kit for collection of salivary flora according to claim 3, wherein: the inner groove comprises a first groove edge and a second groove edge, the first groove edge is integrally connected with the scraper, and the height of the second groove edge is smaller than that of the first groove edge.

5. Kit for collection of salivary flora according to claim 1, wherein: the handheld portion is transparent and hollow tubulose, the tail end cavity and with handheld portion intercommunication, the inner groovy bottom is equipped with the via hole, the via hole with the tail end intercommunication.

6. Kit for collection of salivary flora according to claim 5, wherein: the via hole is close to one side fixedly connected with honeycomb duct of tail end, the honeycomb duct is tubaeform, the honeycomb duct is located in the tail end.

7. Kit for collection of salivary flora according to claim 6, wherein: the handheld part is detachably connected with the tail end.

8. Kit for collection of salivary flora according to claim 5, wherein: the outer side wall of the handheld part is provided with scales.

9. Kit for collection of salivary flora according to claim 1, wherein: the storage box comprises a box body and a box cover, wherein a plurality of fixing grooves used for placing the saliva collecting device are formed in the box body, and the fixing grooves are identical in structure to the appearance structure of the saliva collecting device.

10. A kit for saliva flora collection as claimed in claim 9, wherein: the box body is filled with a first heat preservation layer, the box cover is covered with a second heat preservation layer, and hemispherical protrusions are uniformly arranged on the second heat preservation layer.