CN214896261U - Control device of blood purification equipment - Google Patents

Control device of blood purification equipment Download PDF

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Publication number
CN214896261U
CN214896261U CN202120977384.8U CN202120977384U CN214896261U CN 214896261 U CN214896261 U CN 214896261U CN 202120977384 U CN202120977384 U CN 202120977384U CN 214896261 U CN214896261 U CN 214896261U
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control circuit
blood
signal
blood pump
liquid
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CN202120977384.8U
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董凡
区子友
郭瑶
杨艳秋
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Beijing Jafron Medical Equipment Co Ltd
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Beijing Jafron Medical Equipment Co Ltd
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Abstract

The present application relates to a control device for a blood purification apparatus. The method comprises the following steps: the device comprises a main control circuit, a secondary control circuit, a first slave control circuit, a second slave control circuit, a third slave control circuit and a detection device; the master control circuit is used for outputting a first control signal to a first input end of the first slave control circuit, outputting a second control signal to a first input end of the second slave control circuit and outputting a third control signal to a first input end of the third slave control circuit; the secondary control circuit is used as a new main control circuit when the main control circuit is detected to be in a dead halt state. The problem of mutual interference among the faults of the blood purification equipment, the first slave control circuit, the second slave control circuit and the third slave control circuit when the main control circuit is in a dead halt state is avoided.

Description

Control device of blood purification equipment
Technical Field
The application relates to the technical field of medical instruments, in particular to a control device of blood purification equipment.
Background
After the blood purification equipment leads the human blood out of the body, specific substances in the blood are filtered, and the purified blood is returned to the human body so as to achieve the effect of treating diseases; blood purification equipment belongs to medical instrument, compares in other general electronic equipment, and in the use, needs medical personnel to carry out various complicated, standard operations to blood purification equipment to maintain blood purification equipment's operation safety.
A typical blood purification apparatus adopts a centralized control mode, and when a controller fails, the blood purification apparatus enters a failure operation state, so that the safety performance of the blood purification apparatus is reduced.
SUMMERY OF THE UTILITY MODEL
In view of the above, it is necessary to provide a control device for a blood purification apparatus, so that the operation of the blood purification apparatus is not affected when the controller fails.
A control device of a blood purification apparatus, comprising: the device comprises a main control circuit, a secondary control circuit, a first slave control circuit, a second slave control circuit, a third slave control circuit and a detection device;
the detection end of the main control circuit is connected with the detection end of the secondary control circuit; the output end of the main control circuit and the output end of the secondary control circuit are connected with the first input end of the first slave control circuit, the first input end of the second slave control circuit and the first input end of the third slave control circuit;
the second input end of the first slave control circuit is connected with the first output end of the second slave control circuit; a second input end of the second slave control circuit is connected with the output end of the detection device, and a second output end of the second slave control circuit is connected with the input end of the detection device; the detection end of the detection device is connected with a transmission pipeline of the blood purification equipment;
the master control circuit is used for outputting a first control signal to a first input end of the first slave control circuit, outputting a second control signal to a first input end of the second slave control circuit and outputting a third control signal to a first input end of the third slave control circuit; the secondary control circuit is used as a new main control circuit when detecting that the main control circuit is in a dead halt state;
the first slave control circuit is used for generating an alarm signal according to the first control signal or the pipeline fault signal; the second slave control circuit is used for generating a detection driving signal according to a second control signal; the detection device is used for detecting the flowing state of the liquid in the transmission pipeline according to the detection driving signal and generating a detection signal; the second slave control circuit is also used for generating a pipeline fault signal when the liquid in the transmission pipeline is judged to be in an abnormal state according to the detection signal; the third slave control circuit is used for controlling the liquid flow rate and the liquid flow direction of the liquid in the transmission pipeline according to a third control signal.
In the control device of the blood purification equipment, the secondary control circuit is used as a new main control circuit when the main control circuit is in a dead halt state, and sends a control signal to the slave control circuit connected with the main control circuit in the control device, so that the problem that the blood purification equipment has a single fault when the main control circuit is in the dead halt state is solved. And the main control circuit, the secondary control circuit, the first slave control circuit, the second slave control circuit and the third slave control circuit realize hierarchical control, and when any one of the first slave control circuit, the second slave control circuit and the third slave control circuit connected with the main control circuit and the secondary control circuit in the control device fails, the normal operation of the functional module connected with other normal slave control circuits cannot be influenced, so that the problem of mutual interference among the failures of the first slave control circuit, the second slave control circuit and the third slave control circuit is avoided.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments or the conventional technologies of the present application, the drawings used in the descriptions of the embodiments or the conventional technologies will be briefly introduced below, it is obvious that the drawings in the following descriptions are only some embodiments of the present application, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic view showing the construction of a control device of the blood purification apparatus according to embodiment 1;
FIG. 2 is a schematic view showing the construction of a control device of the blood purifying apparatus in the embodiment 2;
FIG. 3 is a schematic diagram of an embodiment of a bubble detection circuit;
FIG. 4 is a schematic structural view of a control device of the blood purification apparatus in the embodiment 3;
FIG. 5 is a schematic structural view of a control device of the blood purification apparatus according to embodiment 4;
FIG. 6 is a schematic view showing the construction of a control device of the blood purifying apparatus according to embodiment 5;
FIG. 7 is a schematic view showing the entire construction of a control device of the blood purification apparatus according to embodiment 6;
FIG. 8 is a block diagram of a fourth slave control circuit in an embodiment;
FIG. 9 is a schematic diagram of a control surface between fluid infusion temperature, fluid infusion flow rate, and temperature difference in one embodiment.
Detailed Description
To facilitate an understanding of the present application, the present application will now be described more fully with reference to the accompanying drawings. Embodiments of the present application are set forth in the accompanying drawings. This application may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used herein in the description of the present application is for the purpose of describing particular embodiments only and is not intended to be limiting of the application.
As shown in fig. 1, in one embodiment, there is provided a control device of a blood purification apparatus, including: a main control circuit 10, a sub control circuit 20, a first slave control circuit 30, a second slave control circuit 40, a third slave control circuit 50, and a detection device 60;
the detection end of the main control circuit 10 is connected with the detection end of the secondary control circuit 20; the output end of the main control circuit 10 and the output end of the secondary control circuit 20 are connected with a first input end of the first slave control circuit 30, a first input end of the second slave control circuit 40 and a first input end of the third slave control circuit 50;
a second input terminal of the first slave control circuit 30 is connected to a first output terminal of the second slave control circuit 40; a second input terminal of the second slave control circuit 40 is connected to the output terminal of the detection device 60, and a second output terminal of the second slave control circuit 40 is connected to the input terminal of the detection device 60; the detection end of the detection device 60 is connected with the transmission pipeline of the blood purification equipment;
the master control circuit 10 is configured to output a first control signal to a first input terminal of the first slave control circuit 30, output a second control signal to a first input terminal of the second slave control circuit 40, and output a third control signal to a first input terminal of the third slave control circuit 50;
the secondary control circuit 20 is used as a new main control circuit 10 when detecting that the main control circuit 10 is in a dead halt state;
the first slave control circuit 30 is used for generating an alarm signal according to a first control signal or a pipeline fault signal; the second slave control circuit 40 is configured to generate a detection drive signal according to a second control signal; the detection device 60 is used for detecting the flowing state of the liquid in the transmission pipeline according to the detection driving signal and generating a detection signal; the second slave control circuit 40 is also configured to generate a line fault signal when it is determined from the detection signal that the liquid in the transfer line is in an abnormal state; the third slave control circuit 50 is configured to control a liquid flow rate and a liquid flow direction of the liquid in the transfer line according to a third control signal.
In the control device of the blood purification apparatus, the secondary control circuit 20 is used as a new main control circuit 10 to send a control signal to a slave control circuit connected to the main control circuit 10 in the control device when the main control circuit 10 is in a dead halt state, so as to avoid the problem that the blood purification apparatus has a single fault when the main control circuit 10 is in the dead halt state. Furthermore, the master control circuit 10 and the secondary control circuit 20 realize hierarchical control with the first slave control circuit 30, the second slave control circuit 40 and the third slave control circuit 50, and the failure of any one of the first slave control circuit 30, the second slave control circuit 40 and the third slave control circuit 50 connected with the master control circuit 10 and the secondary control circuit 20 in the control device does not affect the normal operation of the functional module connected with other normal slave control circuits, thereby avoiding the problem that the failures of the first slave control circuit 30, the second slave control circuit 40 and the third slave control circuit 50 interfere with each other.
In one embodiment, the secondary control circuit 20 sends a test signal to the main control circuit 10 according to a preset period, and if the secondary control circuit 20 receives a feedback signal sent by the main control circuit 10, it indicates that the main control circuit 10 is halted (in a halt state), and the secondary control circuit 20 serves as a new main control circuit 10 to perform the operation of the original main control circuit 10.
In one embodiment, the secondary control circuit 20 detects whether the primary control circuit 10 outputs the control signal in real time, and if the secondary control circuit 20 detects that the primary control circuit 10 successfully outputs the control signal, it indicates that the primary control circuit 10 is not halted; if the secondary control circuit 20 detects that the main control circuit 10 does not output the control signal, it indicates that the main control circuit 10 is in a dead halt state, and the secondary control circuit 20 immediately replaces the main control circuit 10, that is, the secondary control circuit 20 is used as a new main control circuit 10, and the secondary control circuit 20 realizes centralized control over the first, second and third slave control circuits 30, 40 and 50.
As shown in fig. 2, in one embodiment, the control device of the blood purification apparatus further comprises: the blood purification device comprises a touch screen, an RS232 circuit and an RS485 circuit, wherein the RS232 circuit is located between the touch screen and the main control circuit 10, the RS485 circuit is located between the main control circuit 10 and the secondary control circuit 20, the touch screen is used for receiving operation instructions of a user to respectively control the working states of the main control circuit 10 and the secondary control circuit 20, then the main control circuit 10 outputs control signals according to the operation instructions of the user, and the user controls the working state of the blood purification device through the touch screen. When a user inputs an operation command through the touch screen, the touch screen transmits the operation command to the main control circuit 10 in the form of RS232 communication. The RS485 circuit is used for realizing a bidirectional RS485 communication function between the main control circuit 10 and the secondary control circuit 20; for example, after the main control circuit 10 and the secondary control circuit 20 are powered on successfully, the secondary control circuit 20 transmits the test signal to the main control circuit 10 in an RS485 communication manner, and if the secondary control circuit 20 receives the response signal output by the main control circuit 10, it indicates that the main control circuit 10 is not halted; on the contrary, if the secondary control circuit 20 does not receive the response signal output by the primary control circuit 10, it indicates that the primary control circuit 10 has been halted, i.e. the primary control circuit 10 is in a halt state, it does not mean that the primary control circuit 10 cannot transmit a signal.
In one embodiment, the control device of the blood purification apparatus further comprises an alarm device 70 connected to the first slave control circuit 30, and the first control signal comprises a signal generated by a factor that the blood purification apparatus needs to alarm, for example, a signal generated by an alarm command input by a user on a touch screen.
In one embodiment, the control device of the blood purification apparatus further includes a first IO quantity driving circuit connected to the master control circuit 10, the secondary control circuit 20, and the second slave control circuit 40, respectively, and when the master control circuit 10 outputs a first control signal or the second slave control circuit 40 outputs a line fault signal, the first IO driving circuit transmits the received first control signal or line fault signal to the first slave control circuit 30, so that the first slave control circuit 30 outputs an alarm signal, for example, when the alarm device 70 includes a speaker, the alarm signal includes a sound driving signal, and the speaker emits an alarm sound according to the sound driving signal to implement an alarm function of the blood purification apparatus. Specifically, the first slave control circuit 30 determines the alarm level of the blood purification apparatus according to the emergency degree of the signal source in the first control signal or the pipeline fault signal, and then outputs different sound driving signals to control the alarm device to emit different alarm sounds (the sound intensity or the sound content is different), so that the user can distinguish the alarm sounds of various levels.
In one embodiment, the control device of the blood purification apparatus further comprises a potentiometer-type knob connected to the first slave control circuit 30, through which a user outputs a knob signal when the speaker emits an alarm sound, and the first slave control circuit 30 outputs a volume adjustment signal according to the knob signal to adjust the volume of the alarm sound emitted from the speaker.
In one embodiment, the control device of the blood purification apparatus further comprises an indicator lamp connected to the first slave control circuit 30, and when the first slave control circuit 30 controls the alarm device 70 to alarm, the first slave control circuit 30 simultaneously generates a corresponding light emitting driving signal and transmits the corresponding light emitting driving signal to the indicator lamp through the second IO volume driving circuit, so that the indicator lamp emits an alarm light source to transmit light source alarm information to the user.
In one embodiment, the control device of the blood purification apparatus further comprises a switching value actuator respectively connected to the main control circuit 10 and the secondary control circuit 20, the switching value actuator is used for adjusting a first blood level in an arterial pot in the transmission line and a second blood level in a venous pot in the transmission line according to the level control signal output by the main control circuit 10, the arterial pot and the venous pot are used for buffering the blood flow rate and removing blood bubbles in the transmission line, the levels of the arterial pot and the venous pot are also directly reflecting the flow state of blood in the transmission line, and the levels of the arterial pot and the venous pot are also one of important parameters in the blood purification process. Specifically, the switching value actuator can exhaust or increase air in the venous kettle and/or the arterial kettle, so as to change the air pressure in the venous kettle and/or the arterial kettle, and realize the liquid level regulation function in the venous kettle and/or the arterial kettle.
In one embodiment, a user inputs a liquid level adjusting command for controlling the liquid level of the venous kettle and/or the arterial kettle on the touch screen, the main control circuit 10 outputs a liquid level control signal for controlling the liquid level of the venous kettle and/or the arterial kettle according to the liquid level adjusting command, the first IO driving circuit performs format conversion on the received liquid level control signal and transmits the converted liquid level control signal to the switching value actuator, and the switching value actuator adjusts and controls the liquid level of the venous kettle and/or the arterial kettle according to the received liquid level control signal, so that the liquid level of the venous kettle and/or the arterial kettle is always in a safe state, and the safety of blood flowing in a transmission pipeline in a blood purification process is guaranteed.
In one embodiment, the control device of the blood purification apparatus further comprises at least one stop valve disposed on the arterial line and/or the venous line, the stop valve being configured to control the opening or closing of the transfer line and thus the start or end of the blood purification according to the opening or closing of the stop valve. Only when the stop valve is opened, the blood in the transmission pipeline can flow; the opening/closing amount actuator is also used to control the opening or closing of the shutoff valve. Specifically, a user inputs a switch instruction on the touch screen, the main control circuit 10 generates an on-off control signal according to the switch instruction, the first IO driving circuit performs format conversion on the on-off control signal and outputs the on-off control signal to the switching value executor, and the switching value executor controls the stop valve to open or close according to the on-off control signal after the format conversion so as to start or stop the blood purification process; for example, before blood purification starts, a user inputs a switch instruction on a touch screen, the main control circuit 10 generates an on-off control signal according to the switch instruction, the first IO drive circuit performs format conversion on the on-off control signal and outputs the on-off control signal to the switching value actuator, the switching value actuator controls the stop valve to open according to the on-off control signal after format conversion, the transmission pipeline starts to access blood, and the blood purification equipment starts to purify the blood of a human body. The principle that the opening and closing actuator controls the stop valve to close at the end of blood purification is the same.
In one embodiment, the control device of the blood purification apparatus further comprises a switching value sensor connected to the first IO drive circuit, the switching value sensor being configured to detect a second blood level in the venous pot and a first blood level in the arterial pot and generate a blood level detection signal; when blood exists in a transmission pipeline of the blood purification equipment, a switching value sensor can detect the blood level in a venous kettle or an arterial kettle to obtain a blood level detection signal, the blood level detection signal is output to a main control circuit 10 through a first IO driving circuit, and the main control circuit 10 generates a liquid level control signal according to the blood level detection signal and a preset blood level signal and feeds back the liquid level control signal to a switching value actuator so as to adjust the blood level of the venous kettle and/or the arterial kettle; the feedback control function of the blood level of the venous kettle and/or the arterial kettle can be realized by combining the switching value sensor and the switching value actuator, so that the blood level of the venous kettle and/or the arterial kettle is maintained in a stable and safe state. Specifically, the main control circuit 10 compares the difference between the actual blood liquid level (obtained according to the blood liquid level detection signal) in the venous kettle or the arterial kettle and the preset blood liquid level (obtained according to the preset blood liquid level signal), and then feeds back and adjusts the switching value actuator according to the difference, and the switching value actuator feeds back and adjusts the blood liquid level in the venous kettle or the arterial kettle, so that the blood liquid level in the venous kettle or the arterial kettle is in a stable and safe state; the preset blood level signal may be pre-stored by the main control circuit 10, or may be input by a user on the touch screen.
In one embodiment, the control device of the blood purification apparatus further comprises a bubble detection circuit connected to the first IO driving circuit, the bubble detection circuit is configured to perform bubble detection on blood in the transmission pipeline according to a bubble detection control signal output by the main control circuit 10 and generate a bubble detection signal, the main control circuit 10 is configured to send a first control signal for performing a bubble failure alarm to the first slave control circuit 30 and send a third control signal for controlling the liquid to stop flowing to the third slave control circuit 50 when determining that bubbles exist in the transmission pipeline according to the bubble detection signal. Specifically, the main control circuit 10 outputs a bubble detection control signal to the bubble detection circuit through the first IO driving circuit, and the bubble detection circuit detects whether bubbles appear in the transmission pipeline according to the bubble detection control signal and generates a bubble detection signal; the bubble detection circuit outputs a bubble detection signal to the master control circuit 10, and if the master control circuit 10 judges that bubbles exist in the transfer line according to the bubble detection signal, the first slave control circuit 30 transmits a first control signal for performing a bubble failure alarm, and the third slave control circuit 50 transmits a third control signal for controlling the liquid to stop flowing in the transfer line, thereby promptly stopping the blood purification process.
In one embodiment, the bubble detection circuit comprises an ultrasonic transmitter, an ultrasonic receiver and an amplifier, wherein the transmission pipeline is positioned on a propagation path of ultrasonic waves between the ultrasonic transmitter and the ultrasonic receiver; the ultrasonic transmitter is used for sending ultrasonic waves according to the bubble detection control signals output by the main control circuit 10, the ultrasonic receiver is used for receiving the ultrasonic waves passing through the transmission pipeline and generating ultrasonic detection signals, and the amplifier is used for amplifying the ultrasonic detection signals to obtain the bubble detection signals. Specifically, as shown in fig. 3, whether bubbles appear in the transmission pipeline is detected by an ultrasonic detection method, the ultrasonic transmitter sends out ultrasonic waves after receiving a bubble detection control signal output by the main control circuit 10, the ultrasonic waves are received by the ultrasonic receiver after passing through the transmission pipeline, the ultrasonic receiver generates an ultrasonic detection signal according to the received ultrasonic waves, the ultrasonic detection signal generated is weak because the ultrasonic waves received by the ultrasonic receiver are usually weak, the amplifier is connected with the ultrasonic receiver and amplifies the ultrasonic detection signal to obtain a bubble detection signal, the main control circuit 10 obtains an actual bubble amount in the transmission pipeline according to the bubble detection signal, and when a difference value between the actual bubble amount and a preset bubble amount (the preset bubble amount is usually 0) is greater than a safety threshold value, it is determined that bubbles exist in the transmission pipeline.
As shown in fig. 2, in one embodiment, the second slave control circuit 40 includes a blood leakage control circuit 102, the second control signal includes a blood leakage control signal, the detection device 60 includes a blood leakage detection circuit 202; the blood leakage control circuit 102 is connected to the blood leakage detection circuit 202, and is configured to generate a blood leakage detection driving signal according to a blood leakage control signal output by the main control circuit 10, the blood leakage detection circuit 202 is configured to detect a blood leakage state of the transmission line according to the blood leakage detection driving signal and generate a blood leakage detection signal, the blood leakage control circuit 102 is configured to generate a blood leakage fault signal when it is determined that the transmission line has a blood leakage phenomenon according to the blood leakage detection signal, the first slave control circuit 30 is configured to generate a blood leakage alarm signal according to the blood leakage fault signal, and the main control circuit 10 is configured to send a third control signal to the third slave control circuit 50 according to the blood leakage fault signal, wherein the third control signal controls the liquid to stop flowing. Specifically, in the operation process of the blood purification apparatus, blood exists in the transmission pipeline, the blood leakage detection circuit 202 starts to detect the blood leakage state of the transmission pipeline and generate a blood leakage detection signal when receiving a blood leakage detection driving signal sent by the blood leakage control circuit 102, and transmits the blood leakage detection signal to the blood leakage control circuit 102, and the blood leakage control circuit 102 judges whether a blood leakage phenomenon exists in the transmission pipeline according to the received blood leakage detection signal. If the blood leakage control circuit 102 judges that a blood leakage phenomenon occurs in the transmission pipeline, a blood leakage fault signal is generated and transmitted to the first slave control circuit 30 through the first IO amount driving circuit, and the first slave control circuit 30 generates a blood leakage alarm signal according to the blood leakage fault signal and controls the loudspeaker to give out an alarm sound. Meanwhile, the blood leakage control circuit 102 transmits the blood leakage fault signal to the main control circuit 10 through the first IO volume driving circuit, and the main control circuit 10 outputs a third control signal for controlling the liquid to stop flowing to the third slave control circuit 50 according to the blood leakage fault signal, thereby automatically stopping the blood purification process.
In one embodiment, the blood leakage detection circuit 202 adopts a light source detection mode, firstly, after the detection light source is emitted to the transmission pipeline, the detection light source passing through the transmission pipeline is received, and a blood leakage detection signal is generated according to the received light intensity of the detection light source, the blood leakage control circuit 102 judges whether a blood leakage phenomenon exists in the transmission pipeline according to the light intensity corresponding to the blood leakage detection signal, and the working principle of the blood leakage detection circuit 202 is similar to that of the bubble detection circuit.
As shown in fig. 2, in one embodiment, the second slave control circuit 40 includes a bleed control circuit 104, the second control signal includes a bleed control signal, the detection device 60 includes a bleed detection circuit 204, the bleed control circuit 104 is connected to the bleed detection circuit 204, for generating a blood leading detection drive signal according to the blood leading control signal outputted from the main control circuit 10, the blood leading detection circuit 204 for detecting the blood leading state of the transmission line according to the blood leakage detection drive signal and generating a blood leading detection signal, the blood leading control circuit 104 for, when it is determined that there is a blood leading failure in the transmission line according to the blood leading detection signal, the first slave control circuit 30 generates a blood drawing fault signal based on which the blood drawing alarm signal is generated, and the master control circuit 10 transmits a third control signal for controlling the stop of the flow of the liquid to the third slave control circuit 50 based on the blood drawing fault signal. Specifically, in the initial stage of blood purification (that is, when the blood pump 304 starts to operate, blood starts to flow into the transmission line), the main control circuit 10 outputs a blood leading control signal to the blood leading control circuit 104 through the first IO drive circuit, the blood leading control circuit 104 generates a blood leading detection drive signal according to the blood leading control signal, the blood leading detection circuit 204 starts to detect the blood leading state of the transmission line and generate a blood leading detection signal after receiving the blood leading detection drive signal, and transmits the blood leading detection signal to the blood leading control circuit 104, and the blood leading control circuit 104 determines whether blood is normally drawn in the transmission line according to the received blood leading detection signal. If the blood leading control circuit 104 judges that a blood leading fault occurs in the transmission pipeline, a blood leading fault signal is generated, the blood leading fault signal is transmitted to the first slave control circuit 30 through the first IO amount driving circuit, the first slave control circuit 30 generates a blood leading alarm signal according to the blood leading fault signal, and the loudspeaker is controlled to give out an alarm sound, so that a user can obtain blood leading fault information in the pipeline in real time. Meanwhile, the blood-drawing control circuit 104 transmits the blood-drawing fault signal to the main control circuit 10 through the first IO volume driving circuit, and the main control circuit 10 outputs a third control signal for controlling the liquid to stop flowing to the third slave control circuit 50 according to the blood-drawing fault signal, thereby automatically stopping the blood purification process.
Since the transfer line of the blood purification device has a "priming" step before starting blood purification, the priming operation is specifically: conveying water for injection into the conveying pipeline to exhaust air in the conveying pipeline and remove impurities in the conveying pipeline; after the pre-flushing is finished, the injection water may exist in the transmission pipeline; next, after the blood purification is formally started, the transmission pipeline starts to draw blood from the human body, and the blood-drawing detection circuit 204 detects whether the blood in the transmission pipeline is drawn normally, specifically, detects whether the liquid in the transmission pipeline is blood, and if the blood-drawing control circuit 104 judges that the liquid in the transmission pipeline is blood according to the blood-drawing detection signal, it indicates that the blood purification device draws blood successfully; on the contrary, if the blood drawing control circuit 104 judges that the liquid in the transmission line is not blood (is water for injection) by the blood drawing detection signal, indicating that the blood drawing of the blood purification apparatus has failed, the blood drawing control circuit 104 outputs a blood drawing failure signal to stop the flow of the liquid in the transmission line (stop the blood pump 304) and to give an alarm through a speaker.
In one embodiment, the blood draw detection circuit 204 employs light source detection, which uses the following principle: the absorption intensity of the light source by blood and other liquids (such as physiological saline) is different, and reference may be made to the description of the blood leakage detection circuit 202.
As shown in fig. 2, in one embodiment, the second slave control circuit 40 includes a pressure control circuit 106, the second control signal includes a pressure control signal, the sensing device 60 includes a pressure sensing circuit 206, the pressure control circuit 106 is coupled to the pressure sensing circuit 206, for generating a pressure detection drive signal in accordance with a pressure control signal output from the main control circuit 10, a pressure detection circuit 206 for detecting a pressure in the transmission line in accordance with the pressure detection drive signal and generating a pressure detection signal, a pressure control circuit 106 for, when it is determined from the pressure detection signal that the pressure in the transmission line is in a failure state, a pressure failure signal is generated, the first slave control circuit 30 is adapted to generate a pressure alarm signal in dependence of the pressure failure signal, and the master control circuit 10 is adapted to send a third control signal to the third slave control circuit 50 in dependence of the pressure failure signal, which control liquid to stop flowing. Specifically, the main control circuit 10 outputs a pressure control signal to the pressure control circuit 106 through the RS485 serial port, the pressure control circuit 106 generates a pressure detection driving signal according to the pressure control signal, the pressure detection circuit 206 starts to detect the pressure in the transmission line and generate a pressure detection signal after receiving the pressure detection driving signal, and transmits the pressure detection signal to the pressure control circuit 106, and the pressure control circuit 106 determines whether the pressure in the transmission line is in a failure state according to the received pressure detection signal. If the pressure control circuit 106 judges that the pressure in the transmission pipeline is in a fault state, a pressure fault signal is generated and transmitted to the first slave control circuit 30 through the RS485 serial port, the first slave control circuit 30 generates a pressure alarm signal according to the pressure fault signal, and the loudspeaker is controlled to give out an alarm sound, so that a user can obtain the pressure fault information in the transmission pipeline in real time. Meanwhile, the pressure control circuit 106 transmits the pressure failure signal to the master control circuit 10 through the RS485 serial port, and the master control circuit 10 outputs a third control signal for controlling the liquid to stop flowing to the third slave control circuit 50 according to the pressure failure signal, thereby automatically stopping the blood purification process.
Specifically, the pressure control circuit 106 obtains a pressure detection value in the transmission line according to the pressure detection signal, the pressure control circuit 106 determines a difference between the pressure detection value and a preset pressure value (obtained according to the preset pressure signal), and if the difference exceeds a safety alarm value, the pressure control circuit 106 determines that the pressure in the transmission line is in a failure state. The transmission pipeline includes: the arterial line is connected with an arterial puncture needle which is inserted into an artery of the human body to lead out arterial blood of the human body, the venous line is connected with a venous puncture needle which is inserted into a vein of the human body to lead out purified blood to the vein of the human body; whether the artery puncture needle and the vein puncture needle are well connected in the loop or not can be judged through the pressure detection signal in the transmission pipeline, for example, when the artery puncture needle is not inserted into an artery of a human body, the pressure of the artery pipeline changes, and the actual connection state of the artery puncture needle can be judged through detecting the pressure of the transmission pipeline. The pressure control circuit 106 may preset a pressure signal; the user can also directly input a pressure setting instruction on the touch screen, then the main control circuit 10 outputs a preset pressure signal according to the pressure setting instruction, and outputs the preset pressure signal to the pressure control circuit 106 through the RS485 serial port, and the pressure control circuit 106 generates a preset pressure according to the preset pressure signal.
In one embodiment, the pressure detection circuit 206 includes a first pressure sensor and a second pressure sensor, the pressure detection circuit 206 simultaneously detecting an arterial side pressure on the arterial line side and a venous side pressure on the venous line side, the arterial side pressure being detected by the first pressure sensor disposed on the arterial pot in the arterial line, the venous side pressure being detected by the second pressure sensor disposed on the venous pot in the venous line; according to the scheme, the pressure detection circuit 206 can be used for simultaneously detecting the arterial side pressure and the venous side pressure and then generating pressure detection signals, the pressure control circuit 106 is used for judging whether the arterial side pressure and the venous side pressure are normal or not according to the obtained pressure detection signals and generating pressure fault signals when the arterial side pressure and/or the venous side pressure are in a fault state; the judgment thresholds of the arterial side pressure and the venous side pressure are different, namely the pressure control circuit 106 judges whether the arterial side pressure is in a fault state according to the difference between the arterial side pressure detection value and the preset arterial pressure, judges whether the venous side pressure is in a fault state according to the difference between the venous side pressure detection value and the preset venous pressure, and has the same detection and alarm modes except that the preset pressure is different.
As shown in fig. 2, in one embodiment, the control device of the blood purification apparatus further includes a blood pump device 208, the third slave control circuit 50 includes a blood pump control circuit 108 connected to the blood pump device 208, and the third control signal includes a blood pump 304 control signal;
the blood pump control circuit 108 is configured to generate a blood pump driving signal according to the blood pump control signal, and the blood pump device 208 is configured to control a blood flow rate and a blood flow direction of the blood in the transmission line according to the blood pump driving signal.
In one embodiment, the blood pump device 208 is further configured to send a speed feedback signal to the blood pump control circuit 108, and the blood pump control circuit 108 is further configured to generate a blood pump drive signal based on the blood pump control signal and the speed feedback signal.
Specifically, a user inputs a desired first blood flow rate (for example, 30ml/min) on the touch screen, the main control circuit 10 generates a blood pump control signal according to the first blood flow rate, the RS485 serial port transmits the blood pump control signal to the blood pump control circuit 108 in an RS485 communication manner, the blood pump control circuit 108 generates a blood pump drive signal for adjusting the rotation speed and the steering of the blood pump device 208 according to the blood pump control signal, and the blood pump control circuit 108 can feedback-control the blood pump device 208 according to the feedback information amount (rotation speed feedback signal) of the blood pump device 208, so that the blood pump device 208 can be maintained in a stable operation state according to the instruction of the user.
As shown in fig. 4, in one embodiment, the blood pump device 208 includes a blood pump 304, a blood pump drive circuit 302, a blood pump speed feedback circuit 306;
the blood pump driving circuit 302 is respectively connected with the blood pump control circuit 108 and the blood pump 304; the blood pump rotating speed feedback circuit 306 is respectively connected with the blood pump 304 and the blood pump control circuit 108;
the blood pump control circuit 108 is used for generating a blood pump driving signal according to the blood pump control signal and the rotating speed feedback signal; the blood pump driving circuit 302 is used for adjusting the blood pump rotation speed and blood pump steering of the blood pump 304 according to the blood pump driving signal; the blood pump 304 is used for controlling the flow rate and the flow direction of the blood in the transmission pipeline according to the rotation speed and the rotation direction of the blood pump; the blood pump speed feedback circuit 306 is used for detecting the blood pump speed in the transmission pipeline and generating a speed feedback signal.
Specifically, a user inputs an expected preset blood flow rate and a preset blood flow direction on a touch screen, the main control circuit 10 generates a blood pump control signal according to the preset blood flow rate, and outputs the blood pump control signal to the blood pump control circuit 108 in an RS485 communication mode through an RS485 serial port, the blood pump control circuit 108 obtains a preset rotating speed and a preset steering direction of the blood pump 304 according to the blood pump control signal, and then generates a blood pump driving signal, and the blood pump driving circuit 302 drives the blood pump 304 to rotate according to the blood pump driving signal, so that blood in a transmission pipeline is transmitted at the blood flow rate expected by the user; the blood pump rotating speed feedback circuit 306 is used for detecting the actual rotating speed of the blood pump 304 and outputting a rotating speed feedback signal, the blood pump control circuit 108 is used for obtaining the actual rotating speed of the blood pump 304 according to the rotating speed feedback signal, comparing the difference value between the actual rotating speed and the preset rotating speed, and then controlling the blood pump driving circuit 302 to dynamically adjust the rotating speed of the blood pump 304 according to the difference value and the preset blood flowing speed feedback expected by a user, so that the rotating speed of the blood pump 304 can be kept in a stable state, and the blood flowing speed in a transmission pipeline in the blood purification equipment is kept at a stable level.
In one embodiment, the user may directly control the rotation speed and the steering of the blood pump 304 through a touch screen, and the user may directly control the blood pump 304 to stop or start through the touch screen; wherein controlling the blood pump 304 to stop sets the rotation speed of the blood pump 304 to 0; controlling the blood pump 304 to start is simply setting the blood pump 304 speed from 0 to any value.
As shown in fig. 4, in one embodiment, the blood pump device 208 further comprises:
a blood pump detection module 308 connected to the blood pump 304 and the blood pump control circuit 108, respectively, and configured to detect a blood pump rotation speed and a blood pump rotation direction of the blood pump 304 and generate a blood pump detection signal; the blood pump control circuit 108 is connected with the first slave control circuit 30;
the blood pump control circuit 108 is also configured to determine whether an abnormality occurs in the blood pump 304 based on the blood pump detection signal and the blood pump control signal, generate a blood pump drive signal for controlling the blood pump 304 to stop when the abnormality occurs in the blood pump 304, and send a blood pump fault signal to the first slave control circuit 30.
In one embodiment, the blood pump detection module 308 is a sensor module, and specifically, when the blood pump driving circuit 302 drives the blood pump 304 to operate, the sensor module attached to the blood pump 304 will detect the actual rotation speed and the actual steering of the blood pump 304 to generate a blood pump detection signal, and transmit the blood pump detection signal to the blood pump control circuit 108, and if the blood pump control circuit 108 obtains that the actual rotation speed of the blood pump 304 exceeds the preset safe rotation speed range or the steering of the blood pump 304 does not rotate according to the preset steering according to the detected blood pump detection signal, the blood pump control circuit 108 generates a blood pump fault signal; on one hand, the blood pump control circuit 108 generates a blood pump driving signal according to the blood pump fault signal, and the blood pump driving circuit 302 controls the blood pump 304 to stop emergently according to the blood pump driving signal, so as to ensure the running safety of blood in a transmission pipeline in the blood purification equipment; on the other hand, the blood pump control circuit 108 outputs a blood pump fault signal to the first slave control circuit 30 through the RS485 serial port and the IO drive circuit in sequence, and the first slave control circuit 30 generates a blood pump fault alarm signal according to the blood pump fault signal to control the speaker to give an alarm sound, so as to remind a user that the operation of the blood pump 304 is in a fault state, and the user is required to perform timely processing.
In one embodiment, the blood pump detection module 308 includes a blood pump speed feedback circuit 306.
As shown in fig. 5, in one embodiment, the third slave control circuit 50 includes a fluid replacement control circuit 110, the third control signal includes a fluid replacement control signal, and the control device of the blood purification apparatus further includes:
the blood purification device is used for purifying the purified blood obtained after the blood in the transmission pipeline is purified;
and the fluid infusion unit is connected with the fluid infusion control circuit 110 and is used for receiving a fluid infusion driving signal generated by the fluid infusion control circuit 110 according to the fluid infusion control signal and controlling the flow rate and the flow direction of the supplementary fluid infused into the purified blood according to the fluid infusion driving signal.
In one embodiment, the fluid infusion unit comprises a fluid infusion device 212 and a heating device 210; the control means of the blood purification apparatus further comprise a fourth slave control circuit 80;
the fourth slave control circuit 80 is respectively connected with the main control circuit 10, the secondary control circuit 20 and the heating device 210, and the fourth slave control circuit 80 is used for receiving the heating control signal sent by the main control circuit 10 and generating a heating driving signal according to the heating control signal;
the fluid infusion device 212 is connected with the fluid infusion control circuit 110 and is used for controlling the fluid infusion flow rate and the fluid infusion flow direction of the supplementary fluid in the fluid infusion pipeline in the transmission pipeline according to the fluid infusion driving signal;
the heating device 210 is installed on the surface of the fluid infusion line and is used for heating the fluid infusion according to the heating driving signal.
In one embodiment, the fluid infusion device 212 comprises a fluid infusion pump driving circuit, a fluid infusion pump, and a fluid infusion pump rotation speed feedback circuit;
the fluid infusion pump driving circuit is respectively connected with the fluid infusion pump control circuit and the fluid infusion pump; the rotary speed feedback circuit of the fluid infusion pump is respectively connected with the fluid infusion pump and the control circuit of the fluid infusion pump;
the fluid infusion pump control circuit is used for generating a fluid infusion pump driving signal according to the fluid infusion control signal and the fluid infusion rotating speed feedback signal; the fluid infusion pump driving circuit is used for adjusting the rotating speed of a fluid infusion pump of the fluid infusion pump and the rotation direction of the fluid infusion pump according to a fluid infusion driving signal; the fluid infusion pump is used for controlling a first flow rate and a first flow direction of the make-up fluid in the fluid infusion pipeline according to the rotating speed of the fluid infusion pump and the rotating direction of the fluid infusion pump; the fluid infusion pump rotating speed feedback circuit is used for detecting a first flow rate of the fluid infusion and generating a fluid infusion rotating speed feedback signal.
In one embodiment, the fluid replacement device 212 further includes a replacement fluid storage bag for storing replacement fluid, which is illustratively a replacement fluid containing a substance required by the human body or a therapeutic drug, and the fluid replacement device 212 controls the delivery of the replacement fluid in the fluid replacement line to the venous pot according to the replacement fluid driving signal, so that the replacement fluid is delivered to the vein of the human body together with the purified blood.
As shown in fig. 5, in one embodiment, the third slave control circuit 50 includes a slurry control circuit 112; the blood purification device includes: a plasma separator, purification unit, plasma separation device 214; the third control signal comprises a pulp separation control signal;
the plasma separator is used for separating the blood in the transmission pipeline into plasma and blood cells;
the purifying unit is used for purifying the blood plasma to obtain purified blood plasma;
the plasma separation control circuit 112 is connected to the plasma separation device 214, and is configured to receive the plasma separation control signal sent by the main control circuit 10, and generate a plasma driving signal according to the plasma separation control signal, and the plasma separation device 214 is configured to control the plasma flow direction and the plasma rate of the plasma in the transmission line according to the plasma driving signal; the heating device 210 is installed on the surface of the fluid replacement line and is used for heating the first mixed liquid composed of the replacement liquid and the purified plasma in the fluid replacement line according to the heating driving signal. The fluid infusion pump is used for controlling the flow rate and the flow direction of the first mixed fluid in the fluid infusion pipeline according to the rotating speed of the fluid infusion pump and the rotating direction of the fluid infusion pump; and the fluid infusion pump rotating speed feedback circuit is used for detecting the flow rate of the first mixed liquid and generating a fluid infusion rotating speed feedback signal.
As shown in fig. 5, in one embodiment, the third slave control circuit 50 includes a discard control circuit 114; the blood purification apparatus further comprises: a liquid discarding device 216, a liquid discarding storage bag; the purification module comprises a component separator; the third control signal further comprises a discard control signal;
the component separator is used for obtaining waste liquid and purified plasma after purifying the plasma;
the liquid discarding control circuit 114 is connected to the liquid discarding apparatus 216, and is configured to receive the liquid discarding control signal sent by the main control circuit 10, and generate a liquid discarding driving signal according to the liquid discarding control signal, and the liquid discarding apparatus 216 is configured to control the liquid discarded in the transmission pipeline to flow into the liquid discarding storage bag according to the liquid discarding driving signal.
Specifically, the functions of the plasma separation control circuit 112 and the discarding control circuit 114 are similar to the functions and constituent modules of the blood pump control circuit 108, the discarding device 216 and the plasma separation device 214 are similar to the functions and constituent modules of the blood pump device 208, and are not described in detail here.
In one embodiment, the first control signal comprises a first weight failure signal, the blood purification apparatus further comprises an amplifying circuit connected to the main control circuit 10 and the secondary control circuit 20, and a discard scale and a replacement scale connected to the amplifying circuit, the discard scale is used for detecting the weight increase of the discard storage bag and generating a first weight signal, the replacement scale is used for detecting the weight decrease of the replacement storage bag and generating a second weight signal, the amplifying circuit amplifies the first weight signal and the second weight signal of the detection amount of the replacement scale and outputs the amplified weight signals to the main control circuit 10 through the AD extension circuit, the main control circuit 10 is further used for judging whether the weight change of the discard storage bag and/or the weight change of the replacement storage bag are in a failure state according to the first weight signal and the second weight signal, and when judging that the weight of the discard storage bag and/or the replacement storage bag are in the failure state, generating a first weight fault signal, the master control circuit 10 outputting the first weight fault signal to the first slave control circuit 30 through the first IO volume driving circuit, and controlling the speaker to emit an alarm sound through the first slave control circuit 30; and the main control circuit 10 generates a plasma separation control signal for controlling the plasma separation device 214 to stop, a plasma discarding control signal for controlling the liquid discarding device 216 to stop, and a liquid supplementing control signal for controlling the liquid supplementing device 212 to stop according to the first weight fault signal, so as to prevent the dual-mode plasma exchange from being in a fault state.
In one embodiment, the third slave control circuit 50 includes a filtrate control circuit 116; the blood purification device comprises a blood filter, a filtrate device 218 and a filtrate storage bag, and the third control signal comprises a filtrate control signal;
the blood filter is used for filtering blood to obtain filtrate and purified blood;
the filtrate control circuit 116 is connected to the filtrate device 218, and is configured to receive a filtrate control signal sent by the main control circuit 10, and generate a filtrate driving signal according to the filtrate control signal, and the filtrate device 218 is configured to control filtrate in the transmission line to flow into the filtrate storage bag according to the filtrate driving signal.
As shown in fig. 6, in one embodiment, the heating device 210 includes a heating driving circuit 310, a heating body 312, a first temperature sensor 314;
the heating driving circuit 310 is respectively connected with the fourth slave control circuit 80 and the heating body 312, and is used for generating a heating power signal according to the heating driving signal;
the heating body 312 is installed on the surface of the fluid infusion pipeline and used for heating the fluid infusion in the fluid infusion pipeline according to the heating power signal;
the first temperature sensor 314 is installed in the fluid infusion pipeline and used for detecting the fluid infusion temperature of the heated fluid infusion in the fluid infusion pipeline and generating a temperature detection signal;
the fourth slave control circuit 80 is connected to the first temperature sensor 314 and the first slave control circuit 30, respectively, and is configured to determine whether the fluid replacement temperature is in an abnormal state based on the temperature detection signal and the heating control signal, generate a heating drive signal for controlling the heating body 312 to stop heating when it is determined that the fluid replacement temperature is abnormal, and transmit a temperature failure signal to the first slave control circuit 30.
In one embodiment, the control device of the blood purification apparatus further comprises a plasma interruption detector disposed on the transmission line between the plasma separator and the plasma separation device 214, when the plasma separator separates the blood in the transmission line, the main control circuit 10 outputs a first plasma interruption detection signal, and converts the first plasma interruption detection signal into a first plasma interruption driving signal through the AD expansion and conversion circuit and outputs the first plasma interruption driving signal to the plasma interruption detector, and the plasma interruption detector is configured to detect whether plasma in the transmission line has a plasma interruption phenomenon according to the first plasma interruption driving signal; specifically, the plasma cutoff detector detects whether plasma in the transmission pipeline is cut off in real time and generates a first plasma cutoff detection signal, the amplification circuit amplifies the first plasma cutoff detection signal and outputs the amplified first plasma cutoff detection signal to the main control circuit 10 through the AD expansion and conversion circuit, if the main control circuit 10 judges that the transmission pipeline has a cut-off phenomenon according to the first plasma cutoff detection signal, the main control circuit 10 generates a first plasma cutoff fault signal and outputs the first plasma cutoff fault signal to the first slave control circuit 30 through the first IO volume driving circuit, and the first slave control circuit 30 controls the loudspeaker to give an alarm sound; and the main control circuit 10 outputs a first slurry breaking fault signal to the blood pump control circuit 108 and the slurry separation control circuit 112 through an RS485 serial port, the blood pump control circuit 108 controls the blood pump 304 to stop through the blood pump driving circuit 302 according to the first slurry breaking fault signal, and the slurry separation control circuit 112 controls the plasma to stop flowing through the slurry separation pump driving circuit in the slurry separation device 214 according to the first slurry breaking fault signal so as to prevent the blood purification equipment from being in a 'slurry breaking operation' state.
In one embodiment, the control device of the blood purification apparatus further comprises a fluid replacement cut detector disposed on the fluid replacement line in the transfer line between the fluid replacement pump and the replacement fluid storage bag, wherein after the blood in the transfer line is separated by the plasma separator, the main control circuit 10 outputs a first fluid replacement cut detection signal, converts the first fluid replacement cut detection signal into a first fluid replacement cut driving signal through the AD extension and conversion circuit, and outputs the first fluid replacement cut driving signal to the fluid replacement cut detector, and the fluid replacement cut detector is configured to detect whether the replacement fluid in the fluid replacement line has a cut phenomenon according to the first fluid replacement cut driving signal; specifically, the fluid replacement cut-off detector detects whether the replacement fluid in the fluid replacement pipeline is cut off in real time and generates a first fluid replacement cut-off detection signal, the amplification circuit amplifies the first fluid replacement cut-off detection signal and outputs the signal to the main control circuit 10 through the AD expansion and conversion circuit, if the main control circuit 10 judges that the fluid replacement pipeline has a cut-off phenomenon according to the first fluid replacement cut-off detection signal, the main control circuit 10 generates a first fluid replacement cut-off fault signal and outputs the first fluid replacement cut-off fault signal to the first slave control circuit 30 through the first IO volume driving circuit, and the first slave control circuit 30 controls the loudspeaker to give an alarm sound; and the main control circuit 10 outputs a first fluid infusion and cut-off fault signal to the blood pump control circuit 108 and the fluid infusion control circuit 110 through an RS485 serial port, the blood pump 304 control circuit 108 controls the stop of the blood pump 304 through the blood pump drive circuit 302 according to the first fluid infusion and cut-off fault signal, and the fluid infusion control circuit 110 controls the stop of the fluid infusion pump through the fluid infusion pump drive circuit in the fluid infusion device 212 according to the first fluid infusion and cut-off fault signal so as to prevent the blood infusion purification device from being in a 'cut-off running' state.
As shown in fig. 7, S1 is a plasma separator, S2 is a purification unit, S3 is a plasma kettle, a bubble detection clamp is a bubble detection circuit, a transmission line includes an arterial line, an arterial kettle, a venous kettle and a venous line, an FP pump is a plasma separation pump in the plasma separation device 214, an RP pump is a fluid replacement pump, a DP pump is a waste fluid pump in the waste fluid device 216, W1 is a replacement fluid storage bag, and W2 is a waste fluid storage bag. The replacement liquid storage bag stores the replacement liquid in advance, wherein the components of the replacement liquid can be prepared according to practical application.
The heating body 312 transmits heat to the outer wall of the fluid infusion pipeline without directly contacting the make-up fluid, so that when a first fluid infusion temperature (namely the heating temperature expected by a user) of the make-up fluid is set on the touch screen, the heating temperature of the heating body 312 is controlled by the heating driving circuit 310, the heating body 312 only transmits the heat to the tube wall of the fluid infusion pipeline, and the heat received by the make-up fluid in the fluid infusion pipeline is not the temperature expected by the user (heat loss can be reduced), so when the heating body 312 is adopted to heat the fluid infusion pipeline, if the temperature of the heating body 312 is directly set as the first fluid infusion temperature, a temperature difference exists between the actual temperature of the heated make-up fluid and the expected first fluid infusion temperature; therefore to solve this temperature difference problem; before heating, the first temperature sensor 314 is used to detect the actual temperature of the heated make-up fluid in real time, and then the temperature of the heating body 312 is calibrated.
As shown in fig. 8, in one embodiment, the fourth slave control circuit 80 includes:
a setting module 402, configured to set a first temperature threshold and a second temperature threshold of a fluid replenishment temperature corresponding to a replenishment fluid, and a first rate threshold and a second rate threshold corresponding to a fluid replenishment flow rate;
a calibration module 404, configured to obtain a first calibration temperature of the corresponding heating body 312 according to the second temperature threshold and the second speed threshold, and a first calibration point formed by the second temperature threshold, the second speed threshold, and a first temperature difference between the first calibration temperature and the second temperature threshold; obtaining a second calibration temperature of the corresponding heating body 312 according to the second temperature threshold and the first rate threshold, and a second calibration point formed by the second temperature threshold, the first rate threshold, and a second temperature difference between the second calibration temperature and the second temperature threshold; obtaining a third calibration temperature of the corresponding heating body 312 and a third calibration point formed by a third temperature difference value between the first temperature threshold value, the second speed threshold value and the third calibration temperature and the first temperature threshold value according to the first temperature threshold value and the second speed threshold value; obtaining a fourth calibration temperature of the corresponding heating body 312 according to the first temperature threshold and the first rate threshold, and a fourth calibration point formed by the first temperature threshold, the first rate threshold, and a third temperature difference between the fourth calibration temperature and the first temperature threshold;
a curved surface generation module 406, which establishes a coordinate system with the fluid infusion temperature as an X-axis, the fluid infusion flow rate as a Y-axis, and the temperature difference between the calibration temperature and the temperature threshold of the heating body 312 as a Z-axis, and generates a control curved surface located in the coordinate system with the first calibration point, the second calibration point, the third calibration point, and the fourth calibration point as end points;
the obtaining module 408 is configured to obtain a target fluid infusion temperature and a target fluid infusion flow rate of the fluid infusion according to the heating control signal, and obtain a target calibration temperature corresponding to the target fluid infusion temperature according to the control curved surface;
and an output module 410, configured to generate a heating driving signal according to the target calibration temperature.
In one embodiment, the surface generation module 406: according to the first calibration point, the second calibration point, the third calibration point and the fourth calibration point, a first line segment formed by connecting the first calibration point and the second calibration point, a second line segment formed by connecting the third calibration point and the fourth calibration point, a third line segment formed by connecting the first calibration point and the third calibration point, a fourth line segment formed by connecting the second calibration point and the fourth calibration point and a control curved surface formed by enclosing the first line segment, the second line segment, the third line segment and the fourth line segment are obtained.
In one implementation, the first temperature threshold is a maximum temperature value Tmax of the fluid replacement temperature, the first temperature threshold is a minimum temperature value Tmin of the fluid replacement temperature, the first rate threshold is a maximum rate Vmax of the fluid replacement flow rate, and the second rate threshold is a minimum rate Vmin of the fluid replacement flow rate.
Before a user inputs a desired first fluid infusion temperature on the touch screen, the heating temperature of the heating body 312 needs to be calibrated in advance; setting the position of the first temperature sensor 314 in the fluid infusion pipeline as a target temperature measuring point, wherein the temperature of the supplementing fluid detected by the target temperature measuring point expected by a user is a first fluid infusion temperature, and setting factors influencing the calibration temperature of the heating body 312 include: the first replenishment temperature and the replenishment flow rate (there are many other factors besides these two, such as the size of the tubing, the material of the tubing, the ambient temperature, the length of the tube diameter between the target temperature point and the heating body 312, etc.).
The step of the fourth slave control circuit 80 generating the heating drive signal according to the heating control signal includes: firstly, acquiring a target calibration temperature of the heating body 312 corresponding to the target fluid infusion temperature in the heating control signal; secondly, a heating driving signal is generated according to the target calibration temperature.
Specifically, in the first step, a first temperature threshold value, namely a maximum temperature value Tmax and a second temperature threshold value, namely a minimum temperature value Tmin, of the fluid replacement temperature corresponding to the fluid replacement are set, and a first rate threshold value, namely a maximum rate Vmax and a second temperature threshold value, namely a minimum rate Vmin, of the fluid replacement flow rate corresponding to the fluid replacement are set; the target fluid replacement temperature is between a first temperature threshold and a second temperature threshold, and the target fluid replacement flow rate is between a first rate threshold and a second rate threshold. And secondly, traversing and combining the maximum temperature value Tmax and the minimum temperature value Tmin with the maximum rate Vmax and the minimum rate Vmin to obtain 4 two-dimensional points consisting of a flow rate limit value of a target fluid infusion flow rate and a temperature limit value of a target fluid infusion temperature, wherein the maximum temperature value Tmax and the minimum temperature value Tmin are respectively a point A1 (Tmin, Vmin), a point A2 (Tmin, Vmax), a point A3(Tmax, Vmin) and a point A4(Tmax, Vmax), and the maximum temperature value Tmax is 38 ℃, the minimum temperature value Tmin is 35 ℃, the maximum rate Vmax is 83.3ml/min and the minimum rate Vmin is 16.7 ml/min. At this time, points A1 (35 ℃, 16.7ml/min), A2 (38 ℃, 16.7ml/min), A3 (35 ℃, 83.3ml/min) and A4 (38 ℃, 83.3ml/min) were indicated. Third, obtaining the calibration temperature of the heating body 312 through a fourth slave control circuit 80, specifically, when the heating temperature of the heating body 312 at a point a1 is adjusted so that the fluid infusion flow rate is Vmin (16.7ml/min), the actual fluid infusion temperature detected by the first temperature sensor 314 is Tmin (35 ℃), at this time, the heating temperature of the heating body 312 is the first calibration temperature T1(35.6 ℃), so as to obtain the heating temperatures of the heating body 312 corresponding to the points a2, A3 and a4, wherein the heating temperature corresponding to the point a2 is the second calibration temperature T2(39.2 ℃), the heating temperature corresponding to the point A3 is the third calibration temperature T3(48 ℃), the heating temperature corresponding to the point a4 is the fourth calibration temperature T4(55 ℃), and the temperature difference Δ T between each calibration temperature and the corresponding actual fluid infusion temperature, wherein the first temperature difference Δ T1 corresponding to the point a1 is T1-Tmin, the second temperature difference value corresponding to a2 point is Δ T2-T2-Tmin, the third temperature difference value corresponding to A3 point is Δ T3-T3-Tmax, the fourth temperature difference value corresponding to A4 point is Δ T4-T4-Tmax, and a1 point, a2 point, A3 point and A4 point are updated to obtain 4 three-dimensional points in total of a1 'point (Tmin, Vmin, Δ T1), a 2' point (Tmin, Vmax, Δ T2), A3 'point (Tmax, Vmin, Δ T3) and A4' point (Tmax, Vmax, Δ T4). And fourthly, establishing a coordinate system by taking the fluid infusion temperature as an X axis, the fluid infusion flow rate as a Y axis and the temperature difference value delta T as a Z axis, and then taking a three-dimensional point A1 '(Tmin, Vmin, delta T1), a 2' (Tmin, Vmax, delta T2), A3 '(Tmax, Vmin, delta T3) and a 4' (Tmax, Vmax, delta T4) as four vertexes to form a control curved surface S1, wherein the control curved surface is shown in FIG. 9. Fifthly, when a target fluid replacement flow rate (corresponding to a determined Y value) and a target fluid replacement temperature (corresponding to a determined X value) of a desired fluid replacement are input, the fourth slave control circuit 80 obtains a Z value, namely the calibration temperature of the heating body 312, according to the X value, the Y value and the control area surface S1, and the fourth slave control circuit 80 changes the power of the heating body 312 through the heating driving circuit 310 so that the temperature of the heating body 312 reaches the calibration temperature, thereby improving the heating precision of the fluid replacement.
The temperature and the flow rate of the replenishing liquid expected by a user can be calibrated by forming a control curved surface S1 by 4 three-dimensional points (A1 ', A2', A3 'and A4'), so that the calibrated temperature of the heating body 312 is obtained, the number of the calibrated points of the temperature of the heating body 312 is greatly reduced, the calibration time is saved, meanwhile, the heating temperature of each heating body 312 can be calibrated by adopting the control curved surface, the method has higher temperature calibration continuity (equivalent to 'stepless speed regulation'), and the problem of larger temperature calibration error caused by discontinuity of each calibrated point in the traditional technology is avoided.
In one embodiment, a three-dimensional control curved surface S1 is generated according to 4 three-dimensional points (a1 ', a 2', A3 'and a 4'), which may be formed by replacing a straight line between a1 'and a 2', which is L1, and similarly, a curve between A3 'and a 4' may be replaced by a straight line L2, and connecting L2 and L1 by numerous straight lines (refer to the straight line L3), wherein L3 is a movable line segment with variable length, L1 is one of "guide rails", L2 is another "guide rail", L3 slides directly on the two guide rails to form the control curved surface S1, and the curved surface S1 is a control curved surface set by using the heater 312 to control the flow rate of the fluid infusion corresponding to different target calibration temperatures.
Specifically, the master control circuit, the secondary control circuit, the first slave control circuit, the second slave control circuit, the third slave control circuit and the fourth slave control circuit in the present application are constituted by a single chip and peripheral circuits, for example, an STM32 series chip and a peripheral circuit having a power supply circuit, and the blood pump drive circuit is realized by a THB6128 chip and a peripheral circuit structure thereof.
The above-mentioned embodiments only express several embodiments of the present application, and the description thereof is more specific and detailed, but not construed as limiting the scope of the utility model. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the concept of the present application, which falls within the scope of protection of the present application. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (10)

1. A control device of a blood purification apparatus, characterized by comprising: the device comprises a main control circuit, a secondary control circuit, a first slave control circuit, a second slave control circuit, a third slave control circuit and a detection device;
the detection end of the main control circuit is connected with the detection end of the secondary control circuit; the output end of the main control circuit and the output end of the secondary control circuit are connected with the first input end of the first slave control circuit, the first input end of the second slave control circuit and the first input end of the third slave control circuit;
the second input end of the first slave control circuit is connected with the first output end of the second slave control circuit; a second input end of the second slave control circuit is connected with the output end of the detection device, and a second output end of the second slave control circuit is connected with the input end of the detection device; the detection end of the detection device is connected with a transmission pipeline of the blood purification equipment;
the master control circuit is used for outputting a first control signal to the first input end of the first slave control circuit, outputting a second control signal to the first input end of the second slave control circuit and outputting a third control signal to the first input end of the third slave control circuit;
the secondary control circuit is used as a new main control circuit when the main control circuit is detected to be in a dead halt state;
the first slave control circuit is used for generating an alarm signal according to the first control signal or the pipeline fault signal; the second slave control circuit is used for generating a detection driving signal according to the second control signal; the detection device is used for detecting the flowing state of the liquid in the transmission pipeline according to the detection driving signal and generating a detection signal; the second slave control circuit is also used for generating a pipeline fault signal when the liquid in the transmission pipeline is judged to be in an abnormal state according to the detection signal; the third slave control circuit is used for controlling the liquid flow rate and the liquid flow direction of the liquid in the transmission pipeline according to the third control signal.
2. The control device of claim 1, further comprising a blood pump device, the third slave control circuit comprising a blood pump control circuit connected to the blood pump device, the third control signal comprising a blood pump control signal;
the blood pump control circuit is used for generating a blood pump driving signal according to the blood pump control signal, and the blood pump device is used for controlling the blood flow speed and the blood flow direction of the blood in the transmission pipeline according to the blood pump driving signal.
3. The control device of claim 2, wherein the blood pump device comprises a blood pump, a blood pump drive circuit, a blood pump speed feedback circuit;
the blood pump driving circuit is respectively connected with the blood pump control circuit and the blood pump; the blood pump rotating speed feedback circuit is respectively connected with the blood pump and the blood pump control circuit;
the blood pump control circuit is used for generating a blood pump driving signal according to the blood pump control signal and the rotating speed feedback signal; the blood pump driving circuit is used for adjusting the blood pump rotating speed and blood pump steering of the blood pump according to the blood pump driving signal; the blood pump is used for controlling the blood flow rate and the blood flow direction according to the blood pump rotating speed and the blood pump steering; the blood pump rotating speed feedback circuit is used for detecting the rotating speed of the blood pump and generating the rotating speed feedback signal.
4. The control device of claim 3, wherein the blood pump device further comprises:
the blood pump detection module is respectively connected with the blood pump and the blood pump control circuit and is used for detecting the blood pump rotating speed and the blood pump steering direction and generating a blood pump detection signal; the blood pump control circuit is connected with the first slave control circuit;
the blood pump control circuit is also used for judging whether the blood pump is abnormal or not according to the blood pump detection signal and the blood pump control signal, generating a blood pump driving signal for controlling the blood pump to stop when the blood pump is judged to be abnormal, and sending a blood pump fault signal to the first slave control circuit.
5. The control device of claim 4, wherein the blood pump detection module includes the blood pump speed feedback circuit.
6. The control device of any of claims 2-5, wherein the third slave control circuit comprises a fluid replacement control circuit, the third control signal comprises a fluid replacement control signal, the control device further comprising:
the blood purification device is used for purifying the purified blood obtained after the blood in the transmission pipeline is purified;
and the fluid infusion unit is connected with the fluid infusion control circuit and used for receiving a fluid infusion driving signal generated by the fluid infusion control circuit according to the fluid infusion control signal and controlling the flow rate and the flow direction of the supplementary fluid infused into the purified blood according to the fluid infusion driving signal.
7. The control device according to claim 6, wherein the fluid replacement unit comprises a fluid replacement device and a heating device; the control device of the blood purification apparatus further comprises a fourth slave control circuit;
the fourth slave control circuit is respectively connected with the main control circuit, the secondary control circuit and the heating device, and is used for receiving a heating control signal sent by the main control circuit and generating a heating driving signal according to the heating control signal;
the liquid supplementing device is connected with the liquid supplementing control circuit and used for controlling the liquid supplementing flow rate and the liquid supplementing flow direction of the supplementing liquid in the liquid supplementing pipeline in the transmission pipeline according to the liquid supplementing driving signal;
and the heating device is arranged on the surface of the liquid supplementing pipeline and used for heating the supplementing liquid according to the heating driving signal.
8. The control device according to claim 7, wherein the heating device includes a heating drive circuit, a heating body, a first temperature sensor;
the heating driving circuit is respectively connected with the fourth slave control circuit and the heating body and is used for generating a heating power signal according to the heating driving signal;
the heating body is arranged on the surface of the liquid supplementing pipeline and used for heating the supplementing liquid in the liquid supplementing pipeline according to the heating power signal;
the first temperature sensor is arranged in the fluid infusion pipeline and used for detecting the fluid infusion temperature of the heated fluid infusion in the fluid infusion pipeline and generating a temperature detection signal;
and the fourth slave control circuit is respectively connected with the first temperature sensor and the first slave control circuit and used for judging whether the fluid infusion temperature is in an abnormal state or not according to the temperature detection signal and the heating control signal, generating a heating driving signal for controlling the heating body to stop heating when the fluid infusion temperature is judged to be abnormal, and sending a temperature fault signal to the first slave control circuit.
9. The control device of claim 7, wherein the third slave control circuit comprises a slurry separation control circuit; the blood purification device includes: a plasma separator, a purification unit and a plasma separation device; the third control signal comprises a pulp separation control signal;
the plasma separator is used for separating the blood in the transmission pipeline into plasma and blood cells;
the purifying unit is used for purifying the blood plasma to obtain purified blood plasma;
the plasma separation control circuit is connected with the plasma separation device and used for receiving the plasma separation control signal sent by the main control circuit and generating a plasma driving signal according to the plasma separation control signal, and the plasma separation device is used for controlling the plasma flow direction and the plasma rate of plasma in the transmission pipeline according to the plasma driving signal; the heating device is arranged on the surface of the fluid infusion pipeline and used for heating the first mixed liquid consisting of the supplementing liquid and the purified blood plasma in the fluid infusion pipeline according to the heating driving signal.
10. The control device of claim 9, wherein the third slave control circuit comprises a discard control circuit; the blood purification apparatus further comprises: a liquid discarding device and a liquid discarding storage bag; the purification module comprises a component separator; the third control signal further comprises a discard control signal;
the component separator is used for obtaining waste liquid and purified plasma after purifying the plasma;
the liquid discarding control circuit is connected with the liquid discarding device and used for receiving a liquid discarding control signal sent by the main control circuit and generating a liquid discarding driving signal according to the liquid discarding control signal, and the liquid discarding device is used for controlling the discarded liquid in the transmission pipeline to flow into the liquid discarding storage bag according to the liquid discarding driving signal;
wherein the third slave control circuit further comprises a filtrate control circuit; the blood purification device comprises a blood filter, a filtrate device and a filtrate storage bag, and the third control signal comprises a filtrate control signal;
the blood filter is used for filtering blood to obtain filtrate and purified blood;
the filtrate control circuit is connected with the filtrate device and used for receiving a filtrate control signal sent by the main control circuit and generating a filtrate driving signal according to the filtrate control signal, and the filtrate device is used for controlling filtrate in the transmission pipeline to flow into the filtrate storage bag according to the filtrate driving signal.
CN202120977384.8U 2021-05-08 2021-05-08 Control device of blood purification equipment Active CN214896261U (en)

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113253642A (en) * 2021-05-08 2021-08-13 北京健帆医疗设备有限公司 Control device of blood purification equipment

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113253642A (en) * 2021-05-08 2021-08-13 北京健帆医疗设备有限公司 Control device of blood purification equipment
CN113253642B (en) * 2021-05-08 2024-06-21 北京健帆医疗设备有限公司 Control device for blood purification apparatus

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