CN214895358U

CN214895358U - Sample analyzer

Info

Publication number: CN214895358U
Application number: CN202023084155.8U
Authority: CN
Inventors: 楚孔德; 张普
Original assignee: Suzhou Mairui Technology Co ltd
Current assignee: Shenzhen Mindray Bio Medical Electronics Co Ltd
Priority date: 2020-12-18
Filing date: 2020-12-18
Publication date: 2021-11-26
Anticipated expiration: 2030-12-18

Abstract

The embodiment of the application provides a sample analyzer, which comprises a detection device, a sample adding device and a connecting mechanism, wherein the connecting mechanism connects a pump assembly in the sample adding device to a target component of the sample analyzer, and the target component comprises a side wall, a bracket or a pipeline plate; wherein the connecting mechanism comprises at least two first elastic pieces and at least one second elastic piece; one ends of the at least two first elastic pieces are respectively connected with different positions of the pump assembly, the other ends of the at least two first elastic pieces are connected with the target component, and the at least two first elastic pieces are in a stretching state; the second resilient member is positioned between the pump assembly and the target component and is in a compressed state. The vibration of the pump assembly during operation can be reduced, and the vibration is prevented from being transmitted to the detection device and a sample to be detected to influence the accuracy of sample analysis.

Description

Sample analyzer

Technical Field

The application relates to the technical field of medical equipment, in particular to a sample analyzer.

Background

A sample analyzer is an instrument for measuring and analyzing a sample, and typically includes a cell analyzer, a biochemical analyzer, a urine analyzer, and the like, in which the urine analyzer judges the health condition of a user by analyzing the content of components such as red and white blood cells in the urine of the user. Sample analyzers typically use a pump as a power source for the fluid path throughout the analyzer, such as by transferring a sample to be tested to a testing device such as a microscope. The pump can cause the vibration of detection device and the sample that awaits measuring, influences the accuracy of analysis, for example causes the shake of urine cell in the counting cell, and the cell under the microscope can produce the ghost image, leads to software to calculate cell number mistake, and then causes the judged result inaccurate.

SUMMERY OF THE UTILITY MODEL

The application provides a sample analyzer, aims at solving the pump and can arouse detection device and wait to detect the vibration of the sample, technical problem such as accuracy that influences the analysis.

In a first aspect, an embodiment of the present application provides a sample analyzer, including:

the detection device is used for detecting and analyzing the liquid sample in the sample detection area so as to obtain a corresponding detection result;

the sample adding device comprises a pipeline and a pump assembly, and the pump assembly is used for conveying the liquid sample to the sample detection area through the pipeline and/or discharging the liquid sample in the sample detection area;

a connection mechanism that connects the pump assembly to a target component of the sample analyzer, the target component including a sidewall, a bracket, or a manifold;

wherein the connecting mechanism comprises at least two first elastic members and at least one second elastic member; one ends of the at least two first elastic pieces are respectively connected with different positions of the pump assembly, the other ends of the at least two first elastic pieces are connected with the target component, and the at least two first elastic pieces are in a stretching state; the second resilient member is positioned between the pump assembly and the target component and is in a compressed state.

The embodiment of the application provides a sample analyzer, a pump assembly is hung on a target component through at least two first elastic pieces, and the pump assembly cannot fall off the target component due to the elastic force of the first elastic pieces; by arranging the second elastic member as a support between the pump assembly and the target component, on one hand, the movement of the pump assembly towards the target component, such as the tube plate, can be limited, and on the other hand, the vibration in the direction can be reduced, so that the vibration of the pump during operation is prevented from being transmitted to the detection device and the sample to be detected to influence the accuracy of sample analysis.

It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the disclosure of the embodiments of the application.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.

Fig. 1 is a schematic structural diagram of a sample analyzer provided in an embodiment of the present application;

FIG. 2 is a schematic diagram of the configuration of a urine analyzer in one embodiment;

FIG. 3 is a schematic view of an embodiment of the coupling mechanism in an orientation for coupling the pump assembly to the target component;

FIG. 4 is a schematic view of an alternative orientation of an attachment mechanism for attaching a pump assembly to a target component in one embodiment;

FIG. 5 is a schematic view of another embodiment of a coupling mechanism for coupling a pump assembly to a target component.

Description of reference numerals: 10. a detection device; 11. a sample detection zone; 20. a sample adding device; 21. a pipeline; 22. a pump assembly; 221. a pump body; 222. mounting a plate; 223. a first side; 224. a second side; 201. a first limiting part; 30. a connecting mechanism; 31. a first elastic member; 32. a second elastic member; 41. a sample container; 42. a waste liquid barrel; 50. a target component; 501. a second limiting part.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are some, but not all, embodiments of the present application. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

The flow diagrams depicted in the figures are merely illustrative and do not necessarily include all of the elements and operations/steps, nor do they necessarily have to be performed in the order depicted. For example, some operations/steps may be decomposed, combined or partially combined, so that the actual execution sequence may be changed according to the actual situation.

Some embodiments of the present application will be described in detail below with reference to the accompanying drawings. The embodiments described below and the features of the embodiments can be combined with each other without conflict.

Referring to fig. 1, fig. 1 is a schematic structural diagram of a sample analyzer according to an embodiment of the present disclosure.

The sample analyzer can be used for analyzing components in liquid samples, such as cells, glucose, creatinine, salt crystals and the like in liquid samples such as urine, blood and the like.

As shown in fig. 1, the sample analyzer of the present application includes a description of the reference numerals of the detecting means: 10. a sample addition device 20 and a connection mechanism 30.

Wherein the detection device is indicated by the reference numerals: 10 are used for performing detection analysis on the liquid sample in the sample detection zone 11 to obtain corresponding detection results.

In some embodiments, the sample analyzer is a urine analyzer and the detection device is identified by the reference numeral: 10 comprises: formed component analyzing apparatus, dry chemical analyzing apparatus and/or physical detecting apparatus are denoted by reference numerals: 10.

the urine analyzer analyzes the content of components such as red and white blood cells in the urine of a user to judge the health condition of the user. The urine analyzer may include a dry chemistry analysis module and a formed component analysis device. Wherein the dry chemical analysis device is matched with the urine analysis test strip for use, and performs semi-quantitative or qualitative detection on human urine; the visible component analysis device automatically recognizes and analyzes the visible component in the urine sample by using a digital imaging technique.

Illustratively, the dry chemical analysis apparatus includes a mechanical module, an optical module, and a circuit module. The mechanical module comprises a sample introduction system, a paper selection unit, a sample application unit and a detection unit, wherein the sample introduction system completes automatic sample introduction of the test tube rack, the paper selection unit completes separation and paper falling of test strips, the sample application unit completes sample suction and sample application of test strip reagent blocks, and the detection unit completes transmission of the test strips and detection of a detection head. The light emitted by the light source of the detection head of the optical module irradiates on the reagent blocks of the reagent belt, each reagent block can chemically react with corresponding components in urine, different colors are displayed, and the depth of the color is in proportional relation with the content of specific components in the urine. The circuit module is used for automatically controlling the processing process of the sample, the sorting, the transmission and the detection of the test strip. The circuit control module is composed of a driving circuit board, and realizes motion control of a motor, on-off control of an electromagnetic valve and a pump, detection of an optical coupling signal and the like.

Illustratively, the tangible component analysis apparatus includes a specimen processing module, an optical counting cell module, a microscopic imaging module, and a data processing module. The sample sucking needle and the liquid path module in the sample processing module complete the actions of uniformly mixing, sucking, discharging, positioning and the like of the sample, and the sample processing and sample introduction process is realized. In the optical counting cell module, a sample naturally settles in the counting cell, the counting cell selects quartz glass with good perspective as an inner cavity material, and the bottom is smooth and flat and has no scratch by adopting a laser inner cavity cutting process. Meanwhile, the two ends of the inner cavity are in smooth transition, so that the cleaning dead angle is avoided and the liquid flow is facilitated. The microscopic camera module uses a static development imaging module and consists of a cold light source optical microscope and a counting cell. The digital camera is arranged at the position of an ocular lens of the microscope. Providing an optical resolution of not less than 800 x 600. The objective table is provided with a counting pool. The sample in the counting cell can be automatically scanned according to the program requirement, and the positioning shooting can be carried out on the tangible components in the sample. The data processing module converts various visible components in urine into digital image signals through a CCD (charge coupled device), an image acquisition card and other visual perception equipment, and transmits the digital image signals to a computer image processing and analyzing system, the analyzing software extracts image visible targets according to information such as pixel distribution conditions, gray level change conditions and the like, the visible components are identified through modeling of a characteristic space of the visible components, characteristic sets of all segmented targets are calculated, artificial neural networks imitating human brains are used for classifying and counting the visible components.

Exemplary, physical detection means are illustrated with reference numbers: 10 can be used for quantitatively detecting the urine volume, color, turbidity, smell, relative density of urine and the like.

Exemplarily, as shown in fig. 2, a schematic diagram of a urine analyzer is shown, and reference numerals of a detection device are used for explaining: 10 may comprise a microscope.

Specifically, the sample adding device 20 of the sample analyzer includes a tube 21 and a pump assembly 22, and the pump assembly 22 is used for delivering the liquid sample to the sample detection area 11 through the tube 21 and/or discharging the liquid sample from the sample detection area 11.

As shown in fig. 1, the sample adding device 20 includes a pipe 21 (which may be referred to as an injection pipe 21) for delivering the liquid sample in the sample container 41 to the sample detection area 11, and a pipe 21 (which may be referred to as a discharge pipe 21) for discharging the liquid sample in the sample detection area 11 to the waste liquid tank 42. Wherein a pump assembly 22 is provided on the filling line 21 and/or the discharge line 21.

In some embodiments, the pump assembly 22 comprises a unidirectional pump, or comprises a bidirectional pump.

Illustratively, the sample adding device 20 can share the same pipe 21 when delivering the liquid sample to the sample detection zone 11 and discharging the liquid sample from the sample detection zone 11, and the pump assembly 22 on the pipe 21 can deliver the liquid sample in the container to the sample detection zone 11 through the pipe 21 and discharge the liquid sample from the sample detection zone 11 through the pipe 21.

As shown in fig. 3 and 4, the attachment mechanism 30 attaches the pump assembly 22 to a target component 50 of a sample analyzer, the target component 50 including a sidewall, bracket or tube 21 plate, wherein the tube 21 plate has a tube 21 formed thereon for transporting a liquid sample. It will be appreciated that the target member 50 is not limited to the above three types, and may be a fixed-position member on the sample analyzer.

In some embodiments, as shown in fig. 3 and 4, the pump assembly 22 includes a pump body 221 and a mounting plate 222, the pump body 221 being mounted on the mounting plate 222, the attachment mechanism 30 attaching the mounting plate 222 to the target part 50.

Illustratively, the pump body 221 and the mounting plate 222 are removably coupled. For example, the mounting plate 222 may be attached to the target member 50 via the attachment mechanism 30, and then the pump body 221 may be mounted on the mounting plate 222. Thereby facilitating attachment of the pump assembly 22 to the target component 50, such as facilitating attachment of the pump assembly 22 to the target component 50 when the sample analyzer is compact and in small spaces. Of course, the pump body 221 and the mounting plate 222 may be integrally provided.

Specifically, as shown in fig. 3 and 4, the connection mechanism 30 includes at least two first elastic members 31 and at least one second elastic member 32; one ends of the at least two first elastic members 31 are respectively connected to different positions of the pump assembly 22, the other ends are connected to the target part 50, and the at least two first elastic members 31 are in a stretching state; the second resilient member 32 is located between the pump assembly 22 and the target component 50 and is in a compressed state.

The pump assembly 22 is suspended on the target member 50 by at least two first elastic members 31, and the pump assembly 22 does not fall off the target member 50 due to the elastic force of the first elastic members 31; by providing the second elastic member 32 as a support between the pump assembly 22 and the target component 50, on the one hand, the movement of the pump assembly 22 in the direction of the target component 50, such as the plate of the pipeline 21, can be limited, and on the other hand, the vibration in this direction can be reduced, preventing the transmission of the vibration of the pump during operation to the reference numeral of the detection device: 10 and the sample to be tested, affects the accuracy of the sample analysis.

In some embodiments, the pump assembly 22 is operated with unidirectional vibration, i.e. vibration phenomena occur in all directions, as shown in fig. 3, the pump assembly 22 also vibrates in the transverse and/or longitudinal direction parallel to the target component 50, and these vibrations can be reduced or eliminated by the constraint of the first elastic element 31. Because the first elastic member 31 and the second elastic member 32 have good elasticity and damping effect, the vibration generated by the pump assembly 22 can be greatly absorbed by the first elastic member 31 and the second elastic member 32, thereby achieving good vibration reduction.

In some embodiments, the target part 50 and the pump assembly 22 are provided with holes at the positions for connecting the first elastic member 31, and the ends of the first elastic member 31 can be hooked in the holes to connect the first elastic member 31 with the target part 50 and the pump assembly 22. The connection may be made without a nut and stud lock, thereby facilitating connection of the pump assembly 22 to the target component 50 when the sample analyzer is compact and in tight spaces.

For example, the first elastic member 31 and the second elastic member 32 may include at least one of a metal spring and a rubber spring, but is not limited thereto. For example, the first and second

elastic members

31 and 32 may be springs made of 65Mn steel.

The lengths, the wire diameters and the turns of the first elastic element 31 and the second elastic element 32 can be determined according to the actual assembly effect, so that each first elastic element 31 is in a stressed state.

In some embodiments, when the pump assembly 22 is connected to the target member 50 through the first elastic member 31, the pump assembly 22 is restrained by the first elastic member 31 to a preset position of the target member 50, which is capable of connecting the second elastic member 32. As shown in fig. 3 and 4, when at least two first elastic members 31 of the connection mechanism 30 are connected to corresponding positions of the pump assembly 22 and the target component 50 during assembly, the pump assembly 22 is fixed in position by the tension of the at least two first elastic members 31, and the fixed position is the installation position of the second elastic member 32.

For example, during assembly, the first elastic member 31 may be first connected to the corresponding positions of the pump assembly 22 and the target component 50, so that the pump assembly 22 is limited to the preset position of the target component 50 by the first elastic member 31, and then the second elastic member 32 may be connected between the preset position of the target component 50 and the pump assembly 22. Alternatively, during assembly, one end of the second elastic member 32 may be connected to a predetermined position of the target member 50, the pump assembly 22 may be connected to the other end of the second elastic member 32, and the first elastic member 31 may be connected to corresponding positions of the pump assembly 22 and the target member 50.

In some embodiments, at least two first elastic members 31 in the connection mechanism 30 are symmetrically arranged to apply balanced pulling forces to the pump assembly 22.

Illustratively, as shown in fig. 3 and 4, at least one first elastic member 31 is connected to a first side 223 of the pump assembly 22, at least another first elastic member 31 is connected to a second side 224 of the pump assembly 22, and the first side 223 and the second side 224 are opposite sides of the pump assembly 22.

Specifically, the first side 223 and the second side 224 may be left and right sides, or may be upper and lower sides.

Illustratively, the first elastic members 31 are connected to the first side 223 and the second side 224 in the same number.

Illustratively, the diaphragm of the diaphragm pump in the pump assembly 22 reciprocates between a first side 223 and a second side 224. The diaphragm, when moving, produces a vibration in the direction of motion, which is the primary vibration direction of the pump assembly 22. By connecting the first elastic member 31 on the first side 223, the second side 224 of the pump assembly 22, a tensile force is exerted in the main vibration direction of the pump assembly 22, which enables a good damping. Of course, the diaphragm pump is merely an example, and other types of pumps, such as a peristaltic pump, are also possible.

It will be appreciated that one or more pumps 221 may be included in the pump assembly 22, i.e., without limiting the number of pumps in the pump assembly 22.

In some embodiments, the at least two first elastic members 31 in the connection mechanism 30 exert a pulling force on the pump assembly 22 with a component in a first direction being greater than or equal to a component in a second direction, wherein the first direction is a direction of movement of a diaphragm pump in the pump assembly 22 and the second direction is perpendicular to the first direction.

For example, the first direction is parallel to the longitudinal direction of the target member 50, and the second direction is parallel to the transverse direction of the target member 50. It is of course also possible that the first direction is transverse and the second direction is longitudinal.

The direction of movement of the diaphragm is the primary direction of vibration of the pump assembly 22. By applying a greater pulling force in the main vibration direction, a good vibration damping can be achieved.

It is understood that the connection mechanism 30 may include two, three, four or more first elastic members 31, and the number of the second elastic members 32 is not limited to one. As shown in fig. 5, the connection mechanism 30 includes three first elastic members 31, and each of the three first elastic members 31 applies a pulling force to the pump assembly 22 so that the position of the pump assembly 22 is relatively fixed.

In some embodiments, the axis of the first elastic member 31 is at an angle of 30 to 60 degrees with respect to the target member 50. As shown in fig. 4, the axis of the first elastic member 31 is angled at 30 to 60 degrees, such as 45 degrees, from the plane of the target member 50 adjacent to the pump assembly 22, which can pull the pump assembly 22 toward the target member 50, reducing or eliminating movement of the pump assembly 22 away from the target member 50 during operation. With the second resilient member 32 disposed between the pump assembly 22 and the target member 50, the force of the first resilient member 31 pulling the pump assembly 22 toward the target member 50 may cause the second resilient member 32 to be in a compressed state, and the resilient force of the second resilient member 32 in the compressed state may reduce or eliminate movement of the pump assembly 22 adjacent the target member 50 during operation.

In some embodiments, as shown in fig. 4, a first position-limiting portion 201 is disposed on a side of the pump assembly 22 close to the target component 50, a second position-limiting portion 501 is disposed on the target component 50, one end of the second elastic element 32 is mounted on the first position-limiting portion 201, and the other end of the second elastic element 32 is mounted on the second position-limiting portion 501. So that the second elastic member 32 is not disengaged.

For example, the first position-limiting portion 201 and/or the second position-limiting portion 501 include at least one of a convex pillar and a concave groove. For example, the end of the second elastic member 32 is caught in the groove, and the boss may be disposed at the middle of the second elastic member 32.

According to the sample analyzer provided by the embodiment of the application, the pump assembly is hung on the target component through the at least two first elastic pieces, and the pump assembly cannot fall off the target component due to the elastic force of the first elastic pieces; by arranging the second elastic member as a support between the pump assembly and the target component, on one hand, the movement of the pump assembly towards the target component, such as the tube plate, can be limited, and on the other hand, the vibration in the direction can be reduced, so that the vibration of the pump during operation is prevented from being transmitted to the detection device and the sample to be detected to influence the accuracy of sample analysis.

It is to be understood that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application.

It should also be understood that the term "and/or" as used in this application and the appended claims refers to and includes any and all possible combinations of one or more of the associated listed items.

While the invention has been described with reference to specific embodiments, the scope of the invention is not limited thereto, and those skilled in the art can easily conceive various equivalent modifications or substitutions within the technical scope of the invention. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.

Claims

1. A sample analyzer, comprising:

2. The sample analyzer of claim 1, wherein when the pump assembly is coupled to the target member via the first resilient member, the pump assembly is retained by the first resilient member to a predetermined position of the target member, the predetermined position being capable of coupling to the second resilient member.

3. The sample analyzer of claim 1, wherein at least one of the first resilient members is coupled to a first side of the pump assembly and at least another one of the first resilient members is coupled to a second side of the pump assembly, the first and second sides being opposite sides of the pump assembly.

4. The sample analyzer of claim 3, wherein the first side and the second side have the same number of first resilient members attached thereto.

5. The sample analyzer of claim 3 wherein a diaphragm of a diaphragm pump in the pump assembly reciprocates between the first side and the second side.

6. The sample analyzer of any of claims 1-5, wherein the at least two first elastic members apply a pulling force to the pump assembly with a component in a first direction that is greater than or equal to a component in a second direction, wherein the first direction is a direction of movement of a diaphragm pump in the pump assembly, and the second direction is perpendicular to the first direction.

7. The sample analyzer of any of claims 1-5, wherein an angle between an axis of the first resilient member and the target member is 30 to 60 degrees.

8. The sample analyzer of any one of claims 1-5, wherein the pump assembly has a first position-limiting portion on a side thereof adjacent to the target member, and a second position-limiting portion on the target member, wherein one end of the second elastic member is mounted on the first position-limiting portion, and the other end of the second elastic member is mounted on the second position-limiting portion.

9. The sample analyzer of claim 8, wherein the first and/or second position limiting portions comprise at least one of a post, a groove.

10. The sample analyzer of any of claims 1-5 wherein the pump assembly includes a pump body and a mounting plate, the pump body being mounted on the mounting plate, the attachment mechanism attaching the mounting plate to the target component.

11. The sample analyzer of claim 10, wherein the pump body and the mounting plate are removably coupled.

12. The sample analyzer of any of claims 1-5, wherein the first and second resilient members comprise at least one of a metal spring and a rubber spring.

13. The sample analyzer of any of claims 1-5, wherein the sample analyzer is a urine analyzer, and the detection device comprises: a formed component analyzing apparatus, a dry chemical analyzing apparatus, and/or a physical detecting apparatus.