CN214894872U - Liquid transfer structure and homogeneous phase chemiluminescence detector - Google Patents

Liquid transfer structure and homogeneous phase chemiluminescence detector Download PDF

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Publication number
CN214894872U
CN214894872U CN202120575695.1U CN202120575695U CN214894872U CN 214894872 U CN214894872 U CN 214894872U CN 202120575695 U CN202120575695 U CN 202120575695U CN 214894872 U CN214894872 U CN 214894872U
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assembly
pipetting
wheel
needle body
structure according
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史娟
陈颖
钱希江
王健辉
张阳阳
王宪华
唐明
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Jiangsu Xiekun Biotechnology Co ltd
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Jiangsu Xiekun Biotechnology Co ltd
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Abstract

The utility model provides a move liquid structure and homogeneous phase chemiluminescence detector relates to chemiluminescence immunoassay's technical field. The pipetting structure comprises a bracket, a first direction movement assembly, a second direction movement assembly and a pipetting assembly; the first direction movement assembly is arranged on the support, the second direction movement assembly is arranged on the first direction movement assembly, and the liquid transferring assembly is arranged on the second direction movement assembly. The homogeneous chemiluminescence detector comprises a pipetting structure. The technical effect of good use effect is achieved.

Description

Liquid transfer structure and homogeneous phase chemiluminescence detector
Technical Field
The utility model relates to a chemiluminescence immunoassay technical field particularly, relates to move liquid structure and homogeneous phase chemiluminescence detector.
Background
The homogeneous phase homogeneous chemiluminescence immunoassay technology is a homogeneous phase immunological detection technology which takes receptor microspheres (receptor beads) and donor microspheres (Donor beads) with surfaces coated with biomolecules and the like as carriers. The technology has the advantages of high sensitivity, strong specificity, low background influence, low sample requirement, low consumption, simple analysis operation and wide detection range, can be suitable for the simple interaction of small molecules which can be detected by the traditional ELISA and other chemiluminescence technologies, and can be more competent for the high-throughput detection of the complex interaction of macromolecules.
However, the pipettes in the prior art homogeneous phase homogeneous chemiluminescent immunoassay devices are inefficient to use.
Therefore, it is an important technical problem to be solved by those skilled in the art to provide a liquid transfer structure and a homogeneous chemiluminescence detector with good use effect.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a move liquid structure and homogeneous phase chemiluminescence detector to alleviate the poor technical problem of result of use among the prior art.
In a first aspect, an embodiment of the present invention provides a liquid-transfering structure, which includes a support, a first direction movement assembly, a second direction movement assembly and a liquid-transfering assembly;
the first direction movement assembly is arranged on the support, the second direction movement assembly is arranged on the first direction movement assembly, and the liquid transfer assembly is arranged on the second direction movement assembly.
With reference to the first aspect, embodiments of the present invention provide a possible implementation manner of the first aspect, wherein the first directional movement assembly includes a first power component, a first synchronous belt, and a first supporting seat for supporting the second directional movement assembly;
the first power part is fixedly arranged on the bracket;
a synchronizing wheel is arranged on the bracket, an output wheel is arranged at the output end of the first power part, and the first synchronizing belt is wound on the synchronizing wheel and the output wheel;
the first supporting seat is fixedly connected with the first synchronous belt.
In combination with the first aspect, an embodiment of the present invention provides a possible implementation manner of the first aspect, wherein, a guide rail is provided on the support, the guide rail is used for guiding the first supporting seat, and a sliding seat adapted to the guide rail is provided on the first supporting seat.
With reference to the first aspect, embodiments of the present invention provide a possible implementation manner of the first aspect, wherein a diameter of the synchronizing wheel is smaller than a diameter of the output wheel;
the number of the synchronizing wheels is two.
In combination with the first aspect, an embodiment of the present invention provides a possible implementation manner of the first aspect, wherein the second directional movement assembly includes a second power component, a lead screw, and a second supporting seat for supporting the liquid-transferring assembly;
the second power part is arranged on the first supporting seat, and the screw rod is in transmission connection with the second power part;
the screw rod is provided with a screw rod nut, and the second supporting seat is fixedly arranged on the screw rod nut.
In combination with the first aspect, an embodiment of the present invention provides a possible implementation manner of the first aspect, wherein the output end of the second power component is provided with an active wheel, one end of the lead screw is provided with a driven wheel, and the active wheel is connected with the driven wheel through a second synchronous belt.
With reference to the first aspect, embodiments of the present invention provide a possible implementation manner of the first aspect, wherein the pipetting assembly includes a plunger pump, a pipette and a sample needle for connecting the pipette head;
the sample needle is fixedly arranged on the second supporting seat;
the plunger pump is communicated with the suction pipe, and the suction pipe is inserted into the sample needle.
With reference to the first aspect, embodiments of the present invention provide a possible implementation manner of the first aspect, wherein the sample needle includes a first needle body and a second needle body;
the first needle body is fixedly connected with the second needle body, and a sealing gasket for sealing the suction tube and the sample needle is arranged between the first needle body and the second needle body;
the first needle body is fixedly connected with the second supporting seat, and two convex rings are arranged on the outer wall of the second needle body.
With reference to the first aspect, an embodiment of the present invention provides a possible implementation manner of the first aspect, wherein a reflection sensor for detecting whether the head of the sample needle is assembled with the gun head is disposed on the first support seat.
In a second aspect, an embodiment of the present invention provides a homogeneous phase chemiluminescence detector, including the liquid-transfering structure.
Has the advantages that:
the embodiment of the utility model provides a liquid-transfering structure, which comprises a bracket, a first direction movement component, a second direction movement component and a liquid-transfering component; the first direction movement assembly is arranged on the support, the second direction movement assembly is arranged on the first direction movement assembly, and the liquid transferring assembly is arranged on the second direction movement assembly.
When specifically using, the staff or can control first direction motion subassembly and second motion subassembly through the controller and remove to will move the liquid subassembly and remove to the assigned position, then move the liquid subassembly in the control and carry out work, thereby accomplish and move liquid work, through such setting, the staff of being convenient for controls, and the staff of being convenient for uses.
The embodiment of the utility model provides a pair of homogeneous phase chemiluminescence detector, including moving the liquid structure. The homogeneous chemiluminescence detector has the advantages compared with the prior art, and the details are not repeated here.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the technical solutions in the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a schematic structural diagram of a liquid-transferring structure provided by an embodiment of the present invention;
fig. 2 is an oblique view of a liquid-transferring structure provided by an embodiment of the present invention;
fig. 3 is a side view of a liquid-transferring structure provided by an embodiment of the present invention;
fig. 4 is a cross-sectional view of a liquid-transfering structure provided by the embodiment of the present invention.
Icon:
100-a scaffold; 110-a synchronizing wheel; 120-a guide rail;
200-a first direction motion assembly; 210-a first power member; 211-output wheel; 220-a first synchronization belt; 230-a first support; 231-a reflection sensor; 240-a slide;
300-a second direction motion assembly; 310-a second power member; 311-driving wheel; 320-a screw rod; 321-a screw nut; 322-driven wheel; 330-second support seat; 340-a second synchronous belt;
400-a pipetting assembly; 410-a plunger pump; 420-a straw; 430-a first needle body; 440-a second needle body; 450-a gasket;
500-gun head.
Detailed Description
The technical solution of the present invention will be described clearly and completely with reference to the accompanying drawings, and obviously, the described embodiments are some, but not all embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", and the like, indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically limited otherwise.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," and "fixed" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.
The present invention will be described in further detail below with reference to specific embodiments and with reference to the attached drawings.
Referring to fig. 1, 2, 3 and 4, an embodiment of the present invention provides a pipetting structure, which includes a support 100, a first directional movement assembly 200, a second directional movement assembly 300 and a pipetting assembly 400; the first direction moving assembly 200 is disposed on the support 100, the second direction moving assembly 300 is disposed on the first direction moving assembly 200, and the pipetting assembly 400 is disposed on the second direction moving assembly 300.
When specifically using, the staff or can control first direction movement subassembly 200 and second movement subassembly through the controller and remove to move liquid-transfering assembly 400 to the assigned position, then move liquid-transfering assembly 400 in the control and work, thereby accomplish liquid-transfering work, through such setting, the staff of being convenient for is controlled, and the staff of being convenient for uses.
Specifically, the second direction moving assembly 300 is disposed on the first direction moving assembly 200, and the first direction moving assembly 200 can drive the second direction moving assembly 300 to move when moving, and can drive the pipetting assembly 400 to move when moving the second direction moving assembly 300, so that the pipetting assembly 400 can be moved to a specific position for pipetting or discharging liquid.
Referring to fig. 1, 2, 3 and 4, in an alternative of the present embodiment, a first directional moving assembly 200 includes a first power member 210, a first timing belt 220 and a first supporting seat 230 for carrying a second directional moving assembly 300; the first power member 210 is fixedly arranged on the bracket 100; the bracket 100 is provided with a synchronous wheel 110, the output end of the first power member 210 is provided with an output wheel 211, and a first synchronous belt 220 is wound on the synchronous wheel 110 and the output wheel 211; the first supporting base 230 is fixedly coupled to the first timing belt 220.
Specifically, the first power member 210 starts to work and can drive the output wheel 211 on the output end of the first power member 210 to rotate, so that the output wheel 211 and the synchronizing wheel 110 cooperate to drive the first synchronizing belt 220 to rotate, and the first supporting seat 230 fixedly connected with the first synchronizing belt 220 is driven to move.
Wherein, the first synchronous belt 220 is wound on the synchronous wheel 110 and the output wheel 211, when the first power member 210 drives the output wheel 211 to rotate, the output wheel 211 and the synchronous wheel 110 are matched together to drive the first synchronous belt 220 to rotate, so as to drive the first supporting seat 230 fixedly arranged on the first synchronous belt 220 to move.
It should be noted that the first power component 210 may adopt a stepping motor, a servo motor or other rotating motors, and those skilled in the art can select the type of the first power component 210 according to the actual situation, which is not described herein again.
Referring to fig. 1, 2, 3 and 4, in an alternative of the present embodiment, the bracket 100 is provided with a guide rail 120 for guiding the first supporting seat 230, and the first supporting seat 230 is provided with a sliding seat 240 adapted to the guide rail 120.
Specifically, the guide rail 120 is disposed on the bracket 100, and the sliding seat 240 adapted to the guide rail 120 is disposed on the first supporting seat 230, so that when the first synchronous belt 220 drives the first supporting seat 230 to move, the first supporting seat 230 can move along the guide rail 120.
Referring to fig. 1, 2, 3 and 4, in an alternative to the present embodiment, the synchronizing wheel 110 has a smaller diameter than the output wheel 211; the number of the synchronizing wheels 110 is two.
Specifically, the diameter of the synchronizing wheel 110 is set smaller than that of the output wheel 211, and two synchronizing wheels 110 are provided on the carriage 100.
Referring to fig. 1, 2, 3 and 4, in an alternative of this embodiment, the second directional movement assembly 300 includes a second power member 310, a lead screw 320 and a second support seat 330 for carrying the pipetting assembly 400; the second power member 310 is arranged on the first supporting seat 230, and the screw rod 320 is in transmission connection with the second power member 310; the screw 320 is provided with a screw nut 321, and the second support seat 330 is fixedly arranged on the screw nut 321.
Specifically, when the first power component 210 drives the first supporting seat 230 to move, the second power component 310 arranged on the first supporting seat 230 can move along with the first supporting seat 230, and when the second power component 310 works, the second power component 310 can drive the screw rod 320 to rotate, the screw rod rotates to drive the screw nut to move along the extending direction of the screw rod 320, so that the second supporting seat 330 is driven to move along the extending direction of the screw rod.
It should be noted that the second power member 310 may adopt a stepping motor, a servo motor or other rotating motors, and those skilled in the art can select the type of the second power member 310 according to actual situations, which will not be described herein.
Referring to fig. 1, 2, 3 and 4, in an alternative of this embodiment, an output end of the second power member 310 is provided with a driving wheel 311, one end of the screw rod 320 is provided with a driven wheel 322, and the driving wheel 311 is in transmission connection with the driven wheel 322 through a second synchronous belt.
Specifically, the output end of the second power member 310 is provided with a driving wheel 311, and one end of the screw rod 320 is provided with a driven wheel 322, the second power member 310 can drive the driving wheel 311 to rotate when in operation, and the driving wheel 311 can drive the driven wheel 322 to rotate through the second synchronous belt, so as to drive the screw rod 320 to rotate.
Wherein the other end of the screw 320 is disposed on the first support 230, and a bearing for supporting the screw 320 is disposed on the first support 230.
Referring to fig. 1, 2, 3 and 4, in an alternative to this embodiment, the pipetting assembly 400 comprises a plunger pump 410, a pipette 420 and a sample needle for connecting to a lance tip 500; the sample needle is fixedly arranged on the second supporting seat 330; the plunger pump 410 communicates with a pipette 420, and the pipette 420 is inserted into the sample needle.
Specifically, when the second direction movement assembly 300 moves, the liquid-transferring assembly 400 can be driven to move along the extending direction of the screw rod 320, specifically, the liquid-transferring assembly 400 can move along the vertical direction.
Wherein, the sample needle fixes the gun head 500, then moves to a designated position, and the plunger pump 410 works to enable the gun head 500 on the sample needle to absorb the reagent or discharge the reagent.
Referring to fig. 1, 2, 3 and 4, in an alternative of the present embodiment, the sample needle includes a first needle body 430 and a second needle body 440; the first needle body 430 is fixedly connected with the second needle body 440, and a sealing gasket 450 for sealing the suction pipe 420 and the sample needle is arranged between the first needle body 430 and the second needle body 440; the first needle 430 is fixedly connected with the second support seat 330, and two convex rings are arranged on the outer wall of the second needle 440.
Specifically, a sealing gasket 450 is arranged between the first needle body 430 and the second needle body 440, and the sealing gasket 450 is arranged to keep the sealing between the straw 420 and the second needle body 440, so that it is ensured that the plunger pump 410 can apply positive pressure or negative pressure to the second needle body 440 through the straw 420, and the gun head 500 arranged on the second needle body 440 can suck or discharge the reagent.
Wherein, through set up twice bulge loop at second needle body 440 outer wall, can improve the stability of being connected of second needle body 440 and rifle head 500.
Referring to fig. 1, 2, 3 and 4, in an alternative of this embodiment, a reflection sensor 231 for detecting whether the head of the sample needle is assembled with the gun head 500 is provided on the first support base 230.
Specifically, the reflection sensor 231 is provided in the first support base 230, and whether or not the tip 500 is connected to the second needle body 440 can be checked by the reflection sensor 231.
It should be noted that a first photoelectric door sensor is disposed on the bracket 100 for limiting the moving range of the first supporting seat 230; a second photogate sensor is arranged on the first support seat 230 and used for limiting the moving range of the second support seat 330; a third photogate sensor is provided on the rack 100 for limiting the range of movement of the sample needle.
The homogeneous phase chemiluminescence detector provided by the embodiment comprises a liquid transfer structure.
Specifically, the homogeneous phase chemiluminescence detector provided in this embodiment has the above advantages compared with the prior art, and is not described herein again.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the embodiments of the present invention.

Claims (10)

1. A pipetting structure comprising: a support (100), a first directional motion assembly (200), a second directional motion assembly (300) and a pipetting assembly (400);
the first direction moving assembly (200) is arranged on the bracket (100), the second direction moving assembly (300) is arranged on the first direction moving assembly (200), and the pipetting assembly (400) is arranged on the second direction moving assembly (300).
2. Pipetting structure according to claim 1, characterized in that the first directional movement assembly (200) comprises a first power member (210), a first timing belt (220) and a first support (230) for carrying the second directional movement assembly (300);
the first power part (210) is fixedly arranged on the bracket (100);
a synchronizing wheel (110) is arranged on the bracket (100), an output wheel (211) is arranged at the output end of the first power piece (210), and the first synchronizing belt (220) is wound on the synchronizing wheel (110) and the output wheel (211);
the first supporting seat (230) is fixedly connected with the first synchronous belt (220).
3. Pipetting structure according to claim 2, characterized in that the rack (100) is provided with a guide rail (120) for guiding the first support base (230), and the first support base (230) is provided with a slide (240) adapted to the guide rail (120).
4. Pipetting structure according to claim 3 characterized in that the synchronizing wheel (110) has a diameter smaller than the diameter of the output wheel (211);
the number of the synchronizing wheels (110) is two.
5. Pipetting structure according to claim 2 characterized in that the second directional movement assembly (300) comprises a second power member (310), a screw (320) and a second support (330) for carrying the pipetting assembly (400);
the second power part (310) is arranged on the first supporting seat (230), and the screw rod (320) is in transmission connection with the second power part (310);
the screw rod (320) is provided with a screw rod nut (321), and the second supporting seat (330) is fixedly arranged on the screw rod nut (321).
6. The liquid transfer structure according to claim 5, characterized in that the output end of the second power member (310) is provided with a driving wheel (311), one end of the screw rod (320) is provided with a driven wheel (322), and the driving wheel (311) is in transmission connection with the driven wheel (322) through a second synchronous belt.
7. Pipetting structure according to claim 5, characterized in that the pipetting assembly (400) comprises a plunger pump (410), a pipette (420) and a sample needle for connecting the tip (500);
the sample needle is fixedly arranged on the second supporting seat (330);
the plunger pump (410) is in communication with the pipette (420), the pipette (420) being inserted within the sample needle.
8. Pipetting structure according to claim 7 wherein said sample needle comprises a first needle body (430) and a second needle body (440);
the first needle body (430) is fixedly connected with the second needle body (440), and a sealing gasket (450) for sealing the suction pipe (420) and the sample needle is arranged between the first needle body (430) and the second needle body (440);
the first needle body (430) is fixedly connected with the second supporting seat (330), and two convex rings are arranged on the outer wall of the second needle body (440).
9. Pipetting structure according to claim 8 wherein the first support (230) is provided with a reflection sensor (231) for detecting whether the head of the sample needle is fitted with a tip (500).
10. A homogeneous chemiluminescent detector comprising the pipetting structure of any one of claims 1 to 9.
CN202120575695.1U 2021-03-22 2021-03-22 Liquid transfer structure and homogeneous phase chemiluminescence detector Active CN214894872U (en)

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CN202120575695.1U CN214894872U (en) 2021-03-22 2021-03-22 Liquid transfer structure and homogeneous phase chemiluminescence detector

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CN202120575695.1U CN214894872U (en) 2021-03-22 2021-03-22 Liquid transfer structure and homogeneous phase chemiluminescence detector

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CN214894872U true CN214894872U (en) 2021-11-26

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114134027A (en) * 2021-12-01 2022-03-04 马晟利 Portable fast detector for new coronavirus

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114134027A (en) * 2021-12-01 2022-03-04 马晟利 Portable fast detector for new coronavirus

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