CN214859286U - Preparation device of high-efficient slowly-releasing nano-drug - Google Patents
Preparation device of high-efficient slowly-releasing nano-drug Download PDFInfo
- Publication number
- CN214859286U CN214859286U CN202120735069.4U CN202120735069U CN214859286U CN 214859286 U CN214859286 U CN 214859286U CN 202120735069 U CN202120735069 U CN 202120735069U CN 214859286 U CN214859286 U CN 214859286U
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- Prior art keywords
- pipe
- guide plate
- hopper
- inlet pipe
- ring pipe
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- 239000003814 drug Substances 0.000 title claims abstract description 40
- 229940079593 drug Drugs 0.000 title claims abstract description 16
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 239000007788 liquid Substances 0.000 claims abstract description 27
- 230000007246 mechanism Effects 0.000 claims abstract description 12
- 230000008878 coupling Effects 0.000 claims description 3
- 238000010168 coupling process Methods 0.000 claims description 3
- 238000005859 coupling reaction Methods 0.000 claims description 3
- 239000007921 spray Substances 0.000 claims description 3
- 238000005452 bending Methods 0.000 claims 1
- 230000000149 penetrating effect Effects 0.000 claims 1
- 239000011248 coating agent Substances 0.000 abstract description 23
- 238000000576 coating method Methods 0.000 abstract description 23
- 238000007599 discharging Methods 0.000 abstract description 5
- 238000000034 method Methods 0.000 abstract description 5
- 239000002699 waste material Substances 0.000 abstract description 3
- 230000008859 change Effects 0.000 abstract description 2
- 239000003595 mist Substances 0.000 description 8
- 239000006187 pill Substances 0.000 description 6
- 239000002775 capsule Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 241001233242 Lontra Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000002702 enteric coating Substances 0.000 description 1
- 238000009505 enteric coating Methods 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
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Abstract
The utility model discloses a preparation facilities of high-efficient slowly-releasing nano-drug, including conveying mechanism and ring pipe, the feed liquor pipe is installed to the ring pipe lower extreme, and the shower nozzle is installed to feed liquor pipe upper end, installs the more than guide plate on the left internal face of ring pipe, and the rubber layer is all installed on the surface of guide plate, and the ring pipe is located shower nozzle upper end department and installs the filter plate, and the outer wall of ring pipe is just being equipped with the discharge gate to filter plate department, and the externally mounted of discharge gate has the discharging pipe. The utility model discloses simple structure, the medicine passes through conveying mechanism can divide batch to drop to the toroidal tube in, avoided because of too much causing blockking between the medicine, and along the continuous dropping of guide plate, at the in-process that drops, with the continuous striking in rubber layer, thereby continuous change angle, make coating liquid fog can be comprehensive and the medicine contact, and coating liquid fog can be all the time along the toroidal tube circulation, avoided the waste of coating liquid fog, can be abundant use coating liquid fog.
Description
Technical Field
The utility model relates to a preparation facilities of high-efficient slowly-releasing nanometer medicine.
Background
Research and development of sustained-release drugs have become a very important direction for the development of the domestic and foreign medical industry. The basic principle of slow release is that the medicine is wrapped in the slow release layer by a proper method, and the medicine is released after the slow release layer is dissolved, so that the release, absorption, distribution, metabolism and excretion processes of the medicine in the body are delayed, and the effect of the medicine is prolonged.
The slow release layer of the slow release medicine is also called as coating, so that the slow release layer has a corresponding coating machine, the coating machine is an important device in the field of solid preparation, and generally takes pills as matrix to coat the effective liquid medicine components, thereby realizing various effects of coloring, gastric dissolution, enteric coating, slow release, controlled release and the like.
Traditional medicine pill coating machine adopts the vibration that vibrating motor arouses, makes the pill vibrate to make the gas contact after pill and coating liquid atomizing, thereby make the coating raw materials parcel on the surface of pill, owing to adopt the mode of vibration, can not make the pill disperse completely, so can have the incomplete phenomenon of parcel, influence the quality of medicine.
Disclosure of Invention
The utility model aims to solve the technical problem of providing a preparation facilities of high-efficient slowly-releasing nanometer medicine to solve the problem that proposes in the above-mentioned background art.
The utility model discloses a realize through following technical scheme: the utility model provides a preparation facilities of high-efficient slowly-releasing nanometer medicine, including conveying mechanism and ring canal, the bend of ring canal lower extreme forms a parallel portion, install circulating fan in the parallel portion, the air outlet department that the ring canal lower extreme is close to circulating fan installs the feed liquor pipe perpendicularly, the shower nozzle is installed to feed liquor pipe upper end, install the more than one guide plate on the left internal face of ring canal, the crisscross distribution of the more than one guide plate, the rubber layer is all installed on the surface of guide plate, the surface on rubber layer is equipped with the through-hole that runs through rubber layer and guide plate, the ring canal is located shower nozzle upper end department and installs the filter plate, the outer wall of ring canal is just being equipped with the discharge gate to filter plate department, the externally mounted of discharge gate has the discharging pipe, discharging pipe lower extreme opening sets up, and threaded connection has the collecting vessel, conveying mechanism installs in the ring canal upper end.
As preferred technical scheme, conveying mechanism includes the inlet pipe, the hopper, conveying screw and gear motor, the inlet pipe is installed in the ring pipe upper end, the inlet pipe lower extreme is just setting up to the guide plate, the hopper is installed in the inlet pipe upper end, conveying screw sets up in the inlet pipe, the axostylus axostyle is installed to the conveying screw upper end, the axostylus axostyle upper end extends to in the hopper, and be connected through shaft coupling and gear motor's pivot, install the mount on gear motor's the outer wall, mount one end is installed on the internal face of hopper, the hopper upper end is equipped with the apron of opening or sealed hopper.
As the preferred technical scheme, a bottom plate is arranged on the right side of the annular pipe and is in an L-shaped structure.
As a preferable technical scheme, the cross section of the annular pipe is arranged in a rectangular structure.
As the preferred technical scheme, the guide plates are all arranged in an inclined shape.
The utility model has the advantages that: the utility model discloses simple structure, the medicine passes through conveying mechanism can divide batch to drop to the toroidal tube in, avoided because of too much causing blockking between the medicine, and along the continuous dropping of guide plate, at the in-process that drops, with the continuous striking in rubber layer, thereby continuous change angle, make coating liquid fog can be comprehensive and the medicine contact, and coating liquid fog can be all the time along the toroidal tube circulation, avoided the waste of coating liquid fog, can be abundant use coating liquid fog.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a schematic view of the overall structure of the present invention;
fig. 2 is a cross-sectional view of a middle ring pipe of the present invention.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present invention, and should not be construed as limiting the present invention.
In the description of the present invention, it is to be understood that the terms "center", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are merely for convenience of description and for simplicity of description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.
In the description of the present invention, it should be noted that unless otherwise explicitly stated or limited, the terms "mounted," "connected" and "disposed" are to be construed broadly, and may for example be fixedly connected, disposed, detachably connected, disposed, or integrally connected and disposed. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
As shown in figures 1 and 2, the utility model discloses a high-efficient slow-release nano-drug preparation device, including conveying mechanism and annular pipe 6, the bend of annular pipe 6 lower extreme forms a parallel portion, install circulating fan 9 in the parallel portion, annular pipe 6 lower extreme is close to circulating fan's air outlet department and is installed liquid inlet pipe 10 perpendicularly, liquid inlet pipe 10 upper end is installed shower nozzle 7, install more than one guide plate 15 on the left internal wall of annular pipe 6, more than one guide plate 15 staggered distribution, all install rubber layer 16 on the surface of guide plate 15, the surface of rubber layer 16 is equipped with the through-hole 18 that runs through rubber layer and guide plate, annular pipe 6 is located shower nozzle upper end department and is installed filter screen plate 14, the outer wall of annular pipe 6 just is equipped with discharge gate 13 to filter screen plate department, discharge gate 13's externally mounted has discharging pipe 12, discharging pipe 12 lower extreme opening sets up, and is connected with a collecting cylinder 11 by screw thread, and a conveying mechanism is arranged at the upper end of the annular pipe 6.
In this embodiment, conveying mechanism includes inlet pipe 5, hopper 3, conveyor screw 17 and gear motor 1, inlet pipe 5 is installed in 6 upper ends of ring pipe, 5 lower extremes of inlet pipe are just setting up to the guide plate, hopper 3 is installed in 5 upper ends of inlet pipe, conveyor screw 17 sets up in inlet pipe 5, axostylus axostyle 4 is installed to conveyor screw 17 upper end, axostylus axostyle 4 upper end extends to in the hopper, and be connected with gear motor 1's pivot through the shaft coupling, install the mount on gear motor 1's the outer wall, mount one end is installed on the internal face of hopper 3, 3 upper ends of hopper are equipped with the apron 2 of opening or sealed hopper.
In this embodiment, a bottom plate 8 is installed on the right side of the annular tube 6, and the bottom plate 8 is arranged in an "L" shape.
In this embodiment, the cross-section of the annular tube 6 is rectangular, which facilitates the installation of the guide plate.
In this embodiment, the flow guiding plates 15 are all arranged in an inclined manner, so that the medicine can roll downwards along the flow guiding plates.
When the coating liquid spraying device is used, the cover plate is opened firstly, the medicine is poured into the hopper, and the atomizer and the liquid inlet pipe are connected through the hose, so that coating liquid mist enters the liquid inlet pipe along the hose until the coating liquid mist is sprayed out of the spray head, the sprayed coating liquid mist can be blown by the circulating fan, and the coating liquid mist is continuously circulated in the annular pipe;
the speed reducing motor is started, the speed reducing motor drives the conveying screw rod, the medicines can be discharged downwards in batches through the slowly rotating conveying screw rod, blocking between the medicines due to excessive medicines is avoided, the discharged medicines can fall into the annular pipe and roll continuously along the guide plate, and the discharged medicines continuously impact the rubber layer in the falling process, so that the angle is continuously changed, and the discharged medicines are fully contacted with the circulating coating liquid mist;
the device is sealed by the collecting cylinder and the cover plate, and the coating liquid mist can circulate along the annular pipe all the time, so that the waste of the coating liquid mist is avoided, and the coating liquid mist can be fully used;
wherein, the medicine that drops to the lower extreme can drop in the collecting vessel along the filter screen board that inclines to effectual medicine collection.
Wherein, the capsule liquid fog can upwards blow along filtering the otter board to pass the through-hole and contact with the medicine that drops, the capsule liquid fog also can pass through from the gap between the guide plate, thereby great increase and the contact time of medicine, guarantee the integrality of capsule on the medicine.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that are not thought of through the creative work should be covered within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the protection scope defined by the claims.
Claims (5)
1. A preparation device for high-efficiency slow-release nano-drugs is characterized in that: comprises a conveying mechanism and a ring pipe (6), a parallel part is formed at the bending part of the lower end of the ring pipe (6), a circulating fan (9) is installed in the parallel part, a liquid inlet pipe (10) is vertically installed at the position, close to the air outlet of the circulating fan, of the lower end of the ring pipe (6), a spray head (7) is installed at the upper end of the liquid inlet pipe (10), more than one guide plate (15) is installed on the inner wall surface at the left side of the ring pipe (6), the more than one guide plate (15) are distributed in a staggered manner, a rubber layer (16) is installed on the surface of each guide plate (15), through holes (18) penetrating through the rubber layer and the guide plates are formed in the surface of each rubber layer (16), a filter screen plate (14) is installed at the position, which is positioned at the upper end of the spray head, a discharge hole (13) is formed right opposite to the filter screen plate, a discharge pipe (12) is installed outside the discharge hole (13), the lower end of the discharge pipe (12) is provided with an opening and is in threaded connection with a collecting cylinder (11), and the conveying mechanism is arranged at the upper end of the annular pipe (6).
2. The device for preparing the high-efficiency slow-release nano-drug according to claim 1, is characterized in that: conveying mechanism includes inlet pipe (5), hopper (3), conveying screw (17) and gear motor (1), install in annular tube (6) upper end inlet pipe (5), inlet pipe (5) lower extreme is just setting up to the guide plate, install in inlet pipe (5) upper end hopper (3), conveying screw (17) set up in inlet pipe (5), axostylus axostyle (4) are installed to conveying screw (17) upper end, axostylus axostyle (4) upper end extends to in the hopper, and be connected through the pivot of shaft coupling with gear motor (1), install the mount on the outer wall of gear motor (1), mount one end is installed on the internal face of hopper (3), hopper (3) upper end is equipped with apron (2) of opening or sealed hopper.
3. The device for preparing the high-efficiency slow-release nano-drug according to claim 1, is characterized in that: the right side of the annular pipe (6) is provided with a bottom plate (8), and the bottom plate (8) is arranged in an L-shaped structure.
4. The device for preparing the high-efficiency slow-release nano-drug according to claim 1, is characterized in that: the section of the annular pipe (6) is arranged in a rectangular structure.
5. The device for preparing the high-efficiency slow-release nano-drug according to claim 1, is characterized in that: the guide plates (15) are all arranged in an inclined shape.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120735069.4U CN214859286U (en) | 2021-04-12 | 2021-04-12 | Preparation device of high-efficient slowly-releasing nano-drug |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120735069.4U CN214859286U (en) | 2021-04-12 | 2021-04-12 | Preparation device of high-efficient slowly-releasing nano-drug |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214859286U true CN214859286U (en) | 2021-11-26 |
Family
ID=78949495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202120735069.4U Expired - Fee Related CN214859286U (en) | 2021-04-12 | 2021-04-12 | Preparation device of high-efficient slowly-releasing nano-drug |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214859286U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114788783A (en) * | 2022-04-29 | 2022-07-26 | 青岛百洋制药有限公司 | High-efficiency coating machine for mechanical and electrical integration and coating process thereof |
-
2021
- 2021-04-12 CN CN202120735069.4U patent/CN214859286U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114788783A (en) * | 2022-04-29 | 2022-07-26 | 青岛百洋制药有限公司 | High-efficiency coating machine for mechanical and electrical integration and coating process thereof |
| CN114788783B (en) * | 2022-04-29 | 2024-03-26 | 青岛百洋制药有限公司 | High-efficiency coating machine for electromechanical integration and coating process thereof |
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20211126 |