CN214830333U - Cell disruption device for gene detection - Google Patents
Cell disruption device for gene detection Download PDFInfo
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- CN214830333U CN214830333U CN202120217206.5U CN202120217206U CN214830333U CN 214830333 U CN214830333 U CN 214830333U CN 202120217206 U CN202120217206 U CN 202120217206U CN 214830333 U CN214830333 U CN 214830333U
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- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 23
- 238000001514 detection method Methods 0.000 title claims abstract description 11
- 230000007246 mechanism Effects 0.000 claims abstract description 110
- 238000010438 heat treatment Methods 0.000 claims abstract description 70
- 238000004140 cleaning Methods 0.000 claims description 46
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 11
- 230000002068 genetic effect Effects 0.000 description 5
- 108020004414 DNA Proteins 0.000 description 3
- 108091028043 Nucleic acid sequence Proteins 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 230000006978 adaptation Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
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Abstract
The utility model relates to a gene detection technical field specifically is a cell disruption device for gene detection, including the heated warehouses, the bottom fixedly connected with heating base of heated warehouses, the inside fixedly connected with pad net of heated warehouses, the groove has been seted up at the top of heated warehouses and has been run through, the first connecting block of top fixedly connected with of heated warehouses, the clean mechanism of first connecting block fixedly connected with is passed through at the top of heated warehouses, clean mechanism includes second connecting block and clean piece, the clean piece of one side fixedly connected with of second connecting block, the inside of heated warehouses is provided with broken mechanism. The utility model has the advantages that: through setting up clean mechanism, when using, insert the hot-water storage storehouse with broken mechanism through clean mechanism, when extracting broken mechanism, clean piece cleans broken mechanism's surface to adsorb the drop of water on broken mechanism surface, be convenient for clear up the drop of water, the going on of the actual broken work of being convenient for.
Description
Technical Field
The utility model relates to a gene detection technical field, especially a gene detects uses cell disruption device.
Background
The gene is a genetic basic unit, a DNA or RNA sequence carrying genetic information is copied to transmit the genetic information to the next generation to guide the synthesis of protein to express the genetic information carried by the gene, thereby controlling the property expression of an organism individual, the gene detection is a technology for detecting DNA by blood, other body fluids or cells, and is a method for taking peripheral venous blood or other tissue cells of a detected person, amplifying the gene information, detecting DNA molecular information in the cells of the detected person by a specific device, analyzing whether the gene type, the gene defect and the expression function contained in the DNA molecular information are normal or not, thereby enabling people to know the genetic information of the person, determining the cause of disease or predicting the risk of the body suffering from a certain disease, when the cells are detected, the cells need to be crushed, and part of the cells have certain requirements on the crushing temperature, therefore, the water-bath heating is usually performed during heating, but the heating mechanism in the conventional crushing device is inconvenient to use, for example, when the crushing mechanism is pulled out from the heating mechanism, a large amount of water drops are easily adhered to the surface of the crushing mechanism, the water drops are inconvenient to clean, and the actual crushing work is inconvenient.
SUMMERY OF THE UTILITY MODEL
The utility model aims to overcome the defects of the prior art and provide a cell crushing device for gene detection.
The purpose of the utility model is realized through the following technical scheme: a cell disruption device for gene detection comprises a heating bin, wherein the bottom of the heating bin is fixedly connected with a heating base, the inside of the heating bin is fixedly connected with a mat net, the top of the heating bin is provided with a through groove, the top of the heating bin is fixedly connected with a first connecting block, the top of the heating bin is fixedly connected with a cleaning mechanism through the first connecting block, the cleaning mechanism comprises a second connecting block and a cleaning block, and one side of the second connecting block is fixedly connected with the cleaning block;
a crushing mechanism is arranged inside the heating bin, the crushing mechanism comprises a crushing pipe and a motor, and the motor is arranged at the bottom of the crushing pipe;
the inside fixedly connected with fixed establishment of heated warehouses, fixed establishment includes fixed block, spring, connecting rod, first clamping piece and second clamping piece, the inside swing joint of fixed block has the spring, the inside swing joint of fixed block has the connecting rod, the first clamping piece of one end fixedly connected with of connecting rod, one side fixedly connected with second clamping piece of first clamping piece.
Optionally, the first connecting block is fixedly connected to one side of the through groove, the second connecting block is connected to the outside of the first connecting block in a threaded manner, and the cleaning mechanism is connected to the outside of the first connecting block in a threaded manner through the second connecting block.
Optionally, the number of the fixing mechanisms is three, and the three fixing mechanisms are circumferentially arrayed inside the heating chamber.
Optionally, one end of the connecting rod is matched with the shape and size of the inside of the fixing block, and the connecting rod is movably connected inside the fixing block through a spring.
Optionally, the crushing mechanism is located inside the heating bin, and the crushing mechanism is fixedly connected inside the heating bin through a fixing mechanism.
Optionally, the cleaning block is made of water-absorbing sponge, the cleaning block is a circular ring, the inner diameter of the cleaning block is the same as the outer diameter of the crushing pipe, the inner diameter of the first connecting block is the same as the diameter of the through groove, and the outer diameter of the crushing pipe is smaller than the inner diameter of the first connecting block.
The utility model has the advantages of it is following:
1. by arranging the cleaning mechanism, the bottom of the heating bin is fixedly connected with the heating base, the inside of the heating bin is fixedly connected with the cushion net, the top of the heating bin is provided with a through groove, the top of the heating bin is fixedly connected with the first connecting block, the top of the heating bin is fixedly connected with the cleaning mechanism through the first connecting block, the cleaning mechanism comprises the second connecting block and the cleaning block, one side of the second connecting block is fixedly connected with the cleaning block, the inside of the heating bin is provided with the crushing mechanism, the crushing mechanism comprises a crushing pipe and a motor, the bottom of the crushing pipe is provided with the motor, the cleaning block is made of water-absorbing sponge material and is a circular ring, the inside diameter of the cleaning block is the same as the outside diameter of the crushing pipe, the inside diameter of the first connecting block is the same as the diameter of the through groove, the outside diameter of the crushing pipe is smaller than the inside diameter of the first connecting block, when the crushing mechanism is used, the crushing mechanism is inserted into the heating bin through the cleaning mechanism, when pulling out broken mechanism, clean piece cleans broken mechanism's surface to adsorb the drop on broken mechanism surface, be convenient for clear up the drop, the going on of the actual crushing work of being convenient for.
2. Through setting up fixed establishment, the inside fixedly connected with fixed establishment of heated warehouses, fixed establishment includes the fixed block, a spring, the connecting rod, first clamping piece and second clamping piece, the inside swing joint of fixed block has the spring, the inside swing joint of fixed block has the connecting rod, the first clamping piece of one end fixedly connected with of connecting rod, one side fixedly connected with second clamping piece of first clamping piece, when packing into heated warehouses with broken mechanism, directly insert broken mechanism in the heated warehouses, when in actual use, broken mechanism passes through fixed establishment and fixes the inside at the heated warehouses, promote the stability of broken mechanism when carrying out breakage, and when inserting broken mechanism, broken mechanism pushes away the second clamping piece, can make first clamping piece carry out the centre gripping with broken mechanism, and the in-service use of being convenient for.
Drawings
Fig. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic cross-sectional view of the heating chamber of the present invention;
fig. 3 is a schematic sectional view of the fixing mechanism of the present invention;
fig. 4 is a schematic sectional view of the cleaning mechanism of the present invention.
In the figure: 1-a heating bin, 2-a heating base, 3-a mat, 4-a through groove, 5-a first connecting block, 6-a cleaning mechanism, 601-a second connecting block, 602-a cleaning block, 7-a crushing mechanism, 701-a crushing pipe, 702-a motor, 8-a fixing mechanism, 801-a fixing block, 802-a spring, 803-a connecting rod, 804-a first clamping piece and 805-a second clamping piece.
Detailed Description
The invention will be further described with reference to the accompanying drawings, but the scope of the invention is not limited to the following description.
As shown in fig. 1-4, a cell disruption device for gene detection, which comprises a heating chamber 1, wherein the bottom of the heating chamber 1 is fixedly connected with a heating base 2, the inside of the heating chamber 1 is fixedly connected with a mat net 3, the top of the heating chamber 1 is provided with a through groove 4, the top of the heating chamber 1 is fixedly connected with a first connecting block 5, the top of the heating chamber 1 is fixedly connected with a cleaning mechanism 6 through the first connecting block 5, the cleaning mechanism 6 comprises a second connecting block 601 and a cleaning block 602, and one side of the second connecting block 601 is fixedly connected with the cleaning block 602;
the heating chamber 1 is internally provided with a crushing mechanism 7, the crushing mechanism 7 comprises a crushing pipe 701 and a motor 702, the bottom of the crushing pipe 701 is provided with the motor 702, when the heating chamber is used, the crushing mechanism 7 is inserted into the heating chamber 1 through a cleaning mechanism 6, and when the crushing mechanism 7 is pulled out, the cleaning block 602 wipes the surface of the crushing mechanism 7, so that water drops on the surface of the crushing mechanism 7 are adsorbed, the water drops are convenient to clean, and the actual crushing work is convenient to carry out;
As an optimal technical solution of the utility model: first connecting block 5 fixed connection is in the one side that runs through groove 4, second connecting block 601 threaded connection is in the outside of first connecting block 5, clean mechanism 6 passes through second connecting block 601 threaded connection in the outside of first connecting block 5, the quantity of fixed establishment 8 is three, 8 circumference arrays of three fixed establishment are in the inside of heated warehouses 1, the one end of connecting rod 803 and the inside shape size looks adaptation of fixed block 801, connecting rod 803 passes through spring 802 swing joint in the inside of fixed block 801, crushing mechanism 7 is located the inside of heated warehouses 1, crushing mechanism 7 passes through the inside of fixed establishment 8 fixed connection in heated warehouses 1, clean piece 602 is the sponge material that absorbs water, clean piece 602 is the ring, the inside diameter of clean piece 602 is the same with the outside diameter of broken pipe 701, the inside diameter of first connecting block 5 is the same with the diameter that runs through groove 4, the outside diameter of broken pipe 701 is less than the inside diameter of first connecting block 5.
The working process of the utility model is as follows: when the crushing mechanism 7 is used, the crushing mechanism 7 is inserted into the heating chamber 1 through the cleaning mechanism 6, when the crushing mechanism 7 is pulled out, the cleaning block 602 wipes the surface of the crushing mechanism 7 to adsorb water drops on the surface of the crushing mechanism 7, when the crushing mechanism 7 is loaded into the heating chamber 1, the crushing mechanism 7 is directly inserted into the heating chamber 1, when the crushing mechanism 7 is actually used, the crushing mechanism 7 is fixed inside the heating chamber through the fixing mechanism 8, the stability of the crushing mechanism 7 during crushing is improved, and when the crushing mechanism 7 is inserted, the crushing mechanism 7 pushes the second clamping piece 805 open, namely, the first clamping piece 804 can clamp the crushing mechanism 7.
To sum up, when the cell disruption device for gene detection is used, the cleaning mechanism 6 is arranged, the bottom of the heating bin 1 is fixedly connected with the heating base 2, the inside of the heating bin 1 is fixedly connected with the pad net 3, the top of the heating bin 1 is provided with the through groove 4, the top of the heating bin 1 is fixedly connected with the first connecting block 5, the top of the heating bin 1 is fixedly connected with the cleaning mechanism 6 through the first connecting block 5, the cleaning mechanism 6 comprises the second connecting block 601 and the cleaning block 602, one side of the second connecting block 601 is fixedly connected with the cleaning block 602, the interior of the heating bin 1 is provided with the disruption mechanism 7, the disruption mechanism 7 comprises a disruption tube 701 and a motor 702, the bottom of the disruption tube 701 is provided with the motor 702, the cleaning block 602 is made of water-absorbing sponge, the cleaning block 602 is a circular ring, the inside diameter of the cleaning block 602 is the same as the outside diameter of the disruption tube 701, the inside diameter of the first connecting block 5 is the same as the diameter of the through groove 4, the outer diameter of the crushing pipe 701 is smaller than the inner diameter of the first connecting block 5, when the crushing mechanism 7 is inserted into the heating chamber 1 through the cleaning mechanism 6, when the crushing mechanism 7 is pulled out, the cleaning block 602 wipes the surface of the crushing mechanism 7, so that water drops on the surface of the crushing mechanism 7 are adsorbed, the water drops are convenient to clean, and the actual crushing work is convenient to carry out, by arranging the fixing mechanism 8, the fixing mechanism 8 is fixedly connected to the inside of the heating chamber 1, the fixing mechanism 8 comprises a fixing block 801, a spring 802, a connecting rod 803, a first clamping piece 804 and a second clamping piece 805, the spring 802 is movably connected to the inside of the fixing block 801, the connecting rod 803 is movably connected to the inside of the fixing block 801, one end of the connecting rod 803 is fixedly connected with the first clamping piece 804, one side of the first clamping piece 804 is fixedly connected with the second clamping piece 805, when the crushing mechanism 7 is loaded into the heating chamber 1, directly insert broken mechanism 7 in heating chamber 1, when in actual use, broken mechanism 7 passes through fixed establishment 8 to be fixed in the inside of heating chamber, promotes the stability of broken mechanism 7 when carrying out the breakage, and when inserting broken mechanism 7, broken mechanism 7 backs up second clamping piece 805, can make first clamping piece 804 carry out the centre gripping with broken mechanism 7, the in-service use of being convenient for.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. A cell disruption device for gene detection, characterized in that: the heating device comprises a heating bin (1), wherein the bottom of the heating bin (1) is fixedly connected with a heating base (2), the inside of the heating bin (1) is fixedly connected with a pad net (3), the top of the heating bin (1) is provided with a through groove (4), the top of the heating bin (1) is fixedly connected with a first connecting block (5), the top of the heating bin (1) is fixedly connected with a cleaning mechanism (6) through the first connecting block (5), the cleaning mechanism (6) comprises a second connecting block (601) and a cleaning block (602), and one side of the second connecting block (601) is fixedly connected with the cleaning block (602);
a crushing mechanism (7) is arranged in the heating bin (1), the crushing mechanism (7) comprises a crushing pipe (701) and a motor (702), and the motor (702) is arranged at the bottom of the crushing pipe (701);
the inside fixedly connected with fixed establishment (8) of heating chamber (1), fixed establishment (8) are including fixed block (801), spring (802), connecting rod (803), first clamping piece (804) and second clamping piece (805), the inside swing joint of fixed block (801) has spring (802), the inside swing joint of fixed block (801) has connecting rod (803), the first clamping piece (804) of one end fixedly connected with of connecting rod (803), one side fixedly connected with second clamping piece (805) of first clamping piece (804).
2. The cell disruption device for gene testing according to claim 1, wherein: the cleaning mechanism is characterized in that the first connecting block (5) is fixedly connected to one side of the through groove (4), the second connecting block (601) is in threaded connection with the outer portion of the first connecting block (5), and the cleaning mechanism (6) is in threaded connection with the outer portion of the first connecting block (5) through the second connecting block (601).
3. The cell disruption device for gene testing according to claim 1, wherein: the number of the fixing mechanisms (8) is three, and the three fixing mechanisms (8) are circumferentially arrayed inside the heating bin (1).
4. The cell disruption device for gene testing according to claim 1, wherein: one end of the connecting rod (803) is matched with the shape and size of the inside of the fixing block (801), and the connecting rod (803) is movably connected to the inside of the fixing block (801) through a spring (802).
5. The cell disruption device for gene testing according to claim 1, wherein: crushing mechanism (7) are located the inside of heating chamber (1), crushing mechanism (7) are through fixed establishment (8) fixed connection in the inside of heating chamber (1).
6. The cell disruption device for gene testing according to claim 1, wherein: the cleaning block (602) is made of water-absorbing sponge, the cleaning block (602) is a circular ring, the inner diameter of the cleaning block (602) is the same as the outer diameter of the crushing pipe (701), the inner diameter of the first connecting block (5) is the same as the diameter of the through groove (4), and the outer diameter of the crushing pipe (701) is smaller than the inner diameter of the first connecting block (5).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120217206.5U CN214830333U (en) | 2021-01-26 | 2021-01-26 | Cell disruption device for gene detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120217206.5U CN214830333U (en) | 2021-01-26 | 2021-01-26 | Cell disruption device for gene detection |
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| Publication Number | Publication Date |
|---|---|
| CN214830333U true CN214830333U (en) | 2021-11-23 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202120217206.5U Expired - Fee Related CN214830333U (en) | 2021-01-26 | 2021-01-26 | Cell disruption device for gene detection |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115322875A (en) * | 2022-08-12 | 2022-11-11 | 中科院南昌高新技术产业协同创新研究院 | Stem cell pretreatment device and method |
-
2021
- 2021-01-26 CN CN202120217206.5U patent/CN214830333U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115322875A (en) * | 2022-08-12 | 2022-11-11 | 中科院南昌高新技术产业协同创新研究院 | Stem cell pretreatment device and method |
| CN115322875B (en) * | 2022-08-12 | 2023-06-30 | 中科院南昌高新技术产业协同创新研究院 | Stem cell pretreatment device and method |
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| GR01 | Patent grant | ||
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20211123 |
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| CF01 | Termination of patent right due to non-payment of annual fee |