CN214716432U

CN214716432U - Mirabegron sustained-release tablet granulation equipment

Info

Publication number: CN214716432U
Application number: CN202120239465.8U
Authority: CN
Inventors: 牛犇; 杭夏清
Original assignee: Nanjing Lianzhi Pharmaceutical Technology Co ltd
Current assignee: Nanjing Lianzhi Pharmaceutical Technology Co ltd
Priority date: 2021-01-28
Filing date: 2021-01-28
Publication date: 2021-11-16
Anticipated expiration: 2031-01-28

Abstract

The utility model discloses a mirabegron sustained-release tablet pelletization equipment relates to pelletization equipment technical field, and is not very good for solving current mirabegron sustained-release tablet pelletization equipment pelletization effect, and the practicality is not very high problem. The utility model discloses a granulation machine, including pelletization case, stoving case, water spray plate, supporting tube, first puddler, stirring leaf, and first puddler passes through screw connection with the stirring leaf, the internally mounted of pelletization incasement portion has the second puddler, the cutting tool bit is installed to the below of second puddler, auxiliary motor is all installed to the both sides of pelletization case, agitator motor is installed to the top of pelletization case, the water pump is installed to one side of pelletization case top, the conveyer pipe is installed to one side of water pump.

Description

Mirabegron sustained-release tablet granulation equipment

Technical Field

The utility model relates to a granulation equipment technical field specifically is mirabegron sustained-release tablet granulation equipment.

Background

The mirabegron slow release tablet granulation equipment generally refers to a device for manufacturing mirabegron slow release tablet powder into tablet particles, wherein the mirabegron belongs to aromatic ethanolamine beta 3 adrenergic receptor agonists, acts on bladder detrusor smooth muscle beta 3 adrenergic receptors, relaxes the bladder, promotes the bladder to be full, increases the urine storage capacity, can effectively reduce the urination frequency and improve the frequency of urination caused by overactive bladder; the mirabegron slow release tablet has the advantages that the influence of food on the absorption of the mirabegron slow release tablet can be reduced, the mirabegron slow release tablet can be taken before and after meals, the long-time stable effective blood concentration can be maintained, the curative effect of the medicine is improved, only one tablet is needed in one day, the taking is convenient, and the compliance of patients is improved.

However, the existing mirabegron slow-release tablet granulation equipment has poor granulation effect and low practicability; therefore, the existing requirements are not met, and a mirabegron slow-release tablet granulating device is proposed for the mirabegron slow-release tablet.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide mirabegron sustained-release tablet pelletization equipment to it is not very good to provide current mirabegron sustained-release tablet pelletization equipment pelletization effect in solving above-mentioned background art, and the practicality is not very high problem.

In order to achieve the above object, the utility model provides a following technical scheme: mirabegron sustained-release tablet pelletization equipment, including the pelletization case, the piece of drying is installed to the inner wall of pelletization case, the lubricant film is installed in the outside of piece of drying, the water smoke board is installed to the top of pelletization incasement portion, the stay tube is all installed to the both sides of pelletization incasement portion, the internally mounted of stay tube has first puddler, the stirring leaf is installed to one side of first puddler, and first puddler passes through the screw connection with the stirring leaf, the internally mounted of pelletization case has the second puddler, the cutter head is installed to the below of second puddler.

Preferably, auxiliary motor is all installed to the both sides of pelletization case, agitator motor is installed to the top of pelletization case, the water pump is installed to one side of pelletization case top, the conveyer pipe is installed to one side of water pump, the below of pelletization case is installed and is divided the sieve case, and pelletization case and branch sieve case welded connection.

Preferably, the discharging pipe is installed at the middle position below the granulating box, a butterfly valve is installed inside the discharging pipe, and the discharging pipe is connected with the butterfly valve in a sealing mode.

Preferably, the inner wall of branch sieve case is provided with the mounting groove, the internally mounted of mounting groove has the screen cloth, the spring is all installed to the top and the below in the screen cloth outside, and the spring is provided with a plurality of, and the screen cloth passes through bolted connection with the spring.

Preferably, a discharge hole is formed in the lower portion inside the sieving box, and a vibration motor is installed at the front end of the sieving box.

Preferably, the front end of the granulating tank is provided with a temperature display.

Compared with the prior art, the beneficial effects of the utility model are that:

1. the utility model discloses an installation water smoke board above the inside of pelletization case, water smoke board blowout water smoke, let the medicament powder can glue together, can not too moist simultaneously, pelletization incasement portion installs a set of cutter head and two sets of stirring leaf, the cutter head cuts into less granule with great powder group, two sets of stirring leaves play the effect of quick powder group motion, let the powder group can fully do irregular motion, accelerate the speed that the material becomes the granule, accelerate the dry speed of medicine granule simultaneously, the effectual work efficiency who promotes the device;

2. the utility model discloses an install the branch sieve case in the below of pelletization case, the internally mounted who divides the sieve case has the screen cloth, and the screen cloth plays the effect of branch sieve medicine granule, prevents that the granule from gluing to be linked together, influences the use operation in later stage, divides the front end of sieve case to install vibrating motor, and vibrating motor work drives pelletization case and divides the vibration of sieve case for the medicine granule screening, prevents simultaneously that medicine granule card is inside the screen cloth, has promoted the perfection of device greatly.

Drawings

Fig. 1 is a schematic view of the internal structure of the present invention;

fig. 2 is a cross-sectional view of the present invention;

fig. 3 is a front view of the present invention.

In the figure: 1. a granulation box; 2. an auxiliary motor; 3. a stirring motor; 4. a water pump; 5. a delivery pipe; 6. a screening box; 7. drying the slices; 8. a lubricating film; 9. a water mist plate; 10. supporting a tube; 11. a first stirring rod; 12. stirring blades; 13. a second stirring rod; 14. a cutter head; 15. a discharge pipe; 16. a butterfly valve; 17. mounting grooves; 18. screening a screen; 19. a spring; 20. a discharge port; 21. a temperature display; 22. a vibration motor.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.

Referring to fig. 1-3, the present invention provides an embodiment: millaberon sustained-release tablet pelletization equipment, including pelletization case 1, stoving piece 7 is installed to the inner wall of pelletization case 1, lubricating film 8 is installed in the outside of stoving piece 7, water smoke board 9 is installed to the top of pelletization case 1 inside, stay tube 10 is all installed to the inside both sides of pelletization case 1, the internally mounted of stay tube 10 has first puddler 11, stirring leaf 12 is installed to one side of first puddler 11, and first puddler 11 passes through the screw connection with stirring leaf 12, it is convenient to install and remove, do benefit to the maintenance, can increase the pretightning force and prevent becoming flexible, can not arouse junction material composition phase transition, the internally mounted of pelletization case 1 has second puddler 13, cutter head 14 is installed to the below of second puddler 13.

Further, auxiliary motor 2 is all installed to the both sides of pelletization case 1, agitator motor 3 is installed to the top of pelletization case 1, water pump 4 is installed to one side of pelletization case 1 top, conveyer pipe 5 is installed to one side of water pump 4, branch sieve case 6 is installed to the below of pelletization case 1, and pelletization case 1 and branch sieve case 6 welded connection, welded connection's gas tightness and water proofness are all better, the structural rigidity is also great, the wholeness of structure is good, both labour saving and time saving, the sectional area that does not make the material receive the reduction again, make full use of material.

Furthermore, a discharge pipe 15 is arranged in the middle of the lower portion of the granulating box 1, a butterfly valve 16 is arranged inside the discharge pipe 15, the discharge pipe 15 is connected with the butterfly valve 16 in a sealing mode, and the granulating box is good in fatigue resistance and good in sealing performance, insulating performance and corrosion resistance.

Further, the inner wall of the screening box 6 is provided with a mounting groove 17, the screen 18 is mounted inside the mounting groove 17, the spring 19 is mounted above and below the outer side of the screen 18, the spring 19 is provided with a plurality of pieces, the screen 18 and the spring 19 are connected through bolts, the structure is simple, the form is various, the practicability is high, the operation is convenient, and the connection is reliable.

Further, divide the inside below of sieve case 6 to be provided with discharge gate 20, divide the front end of sieve case 6 to install vibrating motor 22, vibrating motor 22 work drives pelletization case 1 and divides the vibration of sieve case 6 for the medicine granule screening, prevent simultaneously that the medicine granule card is inside screen cloth 18.

Further, the temperature display 21 is installed at the front end of the granulation box 1, so that the temperature inside the granulation box 1 can be known conveniently.

The working principle is as follows: when the powder granulating device is used, medicinal powder is poured into the granulating box 1 through a feeding port on the granulating box 1, then the water pump 4 above the granulating box 1 is started, the water pump 4 conveys water into the water mist plate 9 above the granulating box 1 through the conveying pipe 5 on one side of the water pump 4, the water mist plate 9 sprays water mist, so that medicament powder can be adhered together without being too wet, then the stirring motor 3 above the granulating box 1 and the auxiliary motors 2 on two sides are respectively started, the stirring motor 3 works to drive the output end to rotate, the output end rotates to drive the second stirring rod 13 inside the granulating box 1 and the cutting tool bit 14 below the second stirring rod 13 to simultaneously rotate, the cutting tool bit 14 rotates to cut larger powder lumps into smaller particles, the auxiliary motor 2 works to drive the output end to rotate, the output end rotates to drive the first stirring rod 11 and the stirring blade 12 in the supporting pipes 10 on two sides inside the granulating box 1 to simultaneously rotate, two sets of stirring leaves 12 rotate the effect that plays quick powder group's motion simultaneously, let the powder group can fully be irregular motion, accelerate the speed of material granulation, close water pump 4 after the powder group, open the stoving piece 7 of pelletization case 1 inner wall, dry for the medicine granule, after drying, close agitator motor 3, two auxiliary motor 2 and stoving piece 7, later open the butterfly valve 16 of pelletization case 1 below discharging pipe 15 inside, the medicine granule falls into on the screen cloth 18 of pelletization case 1 below branch sieve case 6 inside, later start the vibrating motor 22 who divides sieve case 6 front end, vibrating motor 22 work drives pelletization case 1 and divides sieve case 6 vibration, accelerate the medicine granule screening, prevent simultaneously that the medicine granule card from inside screen cloth 18, it can to collect the medicine granule of sieving out at last.

It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Claims

1. Mirabegron sustained-release tablet pelletization equipment, including pelletization case (1), its characterized in that: drying plate (7) are installed to the inner wall of pelletization case (1), lubricant film (8) are installed in the outside of drying plate (7), water smoke board (9) are installed to the inside top of pelletization case (1), stay tube (10) are all installed to the inside both sides of pelletization case (1), the internally mounted of stay tube (10) has first puddler (11), stirring leaf (12) are installed to one side of first puddler (11), and just first puddler (11) pass through the screw connection with stirring leaf (12), the internally mounted of pelletization case (1) has second puddler (13), cutting tool bit (14) are installed to the below of second puddler (13).

2. The mirabegron slow release tablet granulation device according to claim 1, characterized in that: auxiliary motor (2) are all installed to the both sides of pelletization case (1), agitator motor (3) are installed to the top of pelletization case (1), water pump (4) are installed to one side of pelletization case (1) top, conveyer pipe (5) are installed to one side of water pump (4), divide sieve case (6) are installed to the below of pelletization case (1), and pelletization case (1) and divide sieve case (6) welded connection.

3. The mirabegron slow release tablet granulation device according to claim 1, characterized in that: the middle position of pelletization case (1) below installs discharging pipe (15), the internally mounted of discharging pipe (15) has butterfly valve (16), and discharging pipe (15) and butterfly valve (16) sealing connection.

4. The mirabegron slow release tablet granulation device according to claim 2, characterized in that: divide the inner wall of sieve case (6) to be provided with mounting groove (17), the internally mounted of mounting groove (17) has screen cloth (18), spring (19) are all installed to the top and the below in screen cloth (18) outside, and spring (19) are provided with a plurality of, and screen cloth (18) pass through bolted connection with spring (19).

5. The mirabegron slow release tablet granulation device according to claim 2, characterized in that: a discharge hole (20) is formed in the lower portion inside the sieving box (6), and a vibration motor (22) is installed at the front end of the sieving box (6).

6. The mirabegron slow release tablet granulation device according to claim 1, characterized in that: the front end of the granulating box (1) is provided with a temperature display (21).