CN214703564U - Intelligent disintegration tester for analysis and detection - Google Patents
Intelligent disintegration tester for analysis and detection Download PDFInfo
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- CN214703564U CN214703564U CN202022846233.7U CN202022846233U CN214703564U CN 214703564 U CN214703564 U CN 214703564U CN 202022846233 U CN202022846233 U CN 202022846233U CN 214703564 U CN214703564 U CN 214703564U
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- disintegration
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Abstract
The utility model discloses an intelligent disintegration tester for analysis and detection, which comprises a thermostatic bath, a case, a lifting mechanism and a test tube rack; a disintegration chamber is arranged below the test tube rack; a supporting plate is arranged in the disintegration chamber; a beaker is placed on the supporting plate; the supporting plate is provided with a locking ring; the beaker is locked by the locking piece; the test tube rack is movably arranged in the beaker up and down; two sides of the supporting plate are hinged with two side walls of the disintegration chamber; the bottom of the thermostatic bath is provided with a slapping mechanism; the slapping mechanism alternatively slaps two sides of the bottom of the supporting plate; the utility model discloses the technical scheme who takes beaker can not automatic simulation stomach's wriggling environment when having solved current appearance of disintegrating use, and temperature distribution is uneven in the constant temperature trough appears easily, leads to the problem that influences the experimental effect.
Description
Technical Field
The utility model relates to an analysis and detection technical field, concretely relates to analysis and detection is with intelligent appearance that disintegrates.
Background
Disintegration refers to the physical dissolution process of a pharmaceutical formulation prior to absorption. The determination of the disintegration time limit generally adopts a lifting disintegration tester, the common tablet can be completely disintegrated within 15min, the hard capsule in the capsule can be completely disintegrated within 30min, and the soft capsule can be completely disintegrated within 1 h. The degree of disintegration refers to the limit of time required for some pharmaceutical dosage forms (tablets, pills, etc.) to completely disintegrate and pass through a screen, as measured under certain conditions using a test device prescribed by pharmacopoeia. The disintegrating medium is usually water, artificial intestinal juice, or artificial gastric juice. The measurement temperature was 37. + -. 0.5 ℃. Is one of the indexes for measuring the quality of the medicine. Along with the continuous method of machine modernization, the disintegration instruments in the market are irregular, and have defects and shortcomings to a certain extent. When the existing disintegration tester is used, the beaker cannot automatically simulate the peristaltic environment of the stomach, and the temperature distribution in the thermostatic bath is uneven, so that the experimental effect is affected.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide an analysis and detection is with intelligence appearance that disintegrates solves the peristaltic environment that the beaker can not automatic simulation stomach when current appearance that disintegrates uses, and temperature distribution is uneven in the constant temperature trough appears easily, leads to influencing the problem of experimental effect.
In order to solve the technical problem, the utility model adopts the following technical scheme: an intelligent disintegration tester for analysis and detection comprises a thermostatic bath, a case, a lifting mechanism and a test tube rack; a disintegration chamber is arranged below the test tube rack; a supporting plate is arranged in the disintegration chamber; a beaker is placed on the supporting plate; the supporting plate is provided with a locking ring; the locking ring locks the beaker; the test tube rack is movably arranged in the beaker up and down; two sides of the supporting plate are hinged with two side walls of the disintegration chamber; the bottom of the thermostatic bath is provided with a slapping mechanism; the slapping mechanism alternatively slaps two sides of the bottom of the supporting plate;
further, the slapping mechanism comprises a first rotating shaft and a second rotating shaft which are arranged side by side; a first eccentric wheel is arranged on the first rotating shaft; a second eccentric wheel is arranged on the second rotating shaft; when the first rotating shaft and the second rotating shaft are driven by the driver to rotate, the first eccentric wheel and the second eccentric wheel alternately slap two sides of the bottom of the supporting plate;
further, the rotating directions of the first rotating shaft and the second rotating shaft are opposite;
further, a first elastic part is arranged at the end part of the first eccentric wheel; a second elastic part is arranged at the end part of the second eccentric wheel; the end surfaces of the first elastic part and the second elastic part are arc surfaces;
further, flange parts extend outwards from two sides of the supporting plate; the inner wall of the disintegration chamber is provided with a limiting part corresponding to the flange part; the limiting part is used for limiting the tilting height of the supporting plate;
furthermore, rotating rods are oppositely arranged on two sides of the supporting plate; the rotating rod is rotatably connected with the side wall of the disintegration chamber;
further, a partition plate is arranged in the thermostatic bath; the partition board divides more than two disintegration chambers in the thermostatic bath; each disintegration chamber is internally and correspondingly provided with a supporting plate;
the further technical proposal is that two sides of the clapboard are connected with the inner wall of the thermostatic chamber; the edge of the lower end of the partition plate is positioned above the slapping mechanism.
Compared with the prior art, the beneficial effects of the utility model are one of following at least:
1. the support plate in the disintegration chamber is used for placing and fixing the beaker, and after two sides of the support plate are hinged with two side walls of the disintegration chamber, the support plate is favorable for driving the beaker on the support plate to generate proper shaking after receiving the flapping shaking of the bottom flapping mechanism, so that the gastric peristalsis environment can be simply simulated, the medicine and the medium in the beaker are favorably mixed and contacted, and the disintegration effect is favorably improved;
2. the locking ring arranged on the supporting plate is beneficial to fixing the beaker placed on the supporting plate, and the supporting plate can be stably placed when the beaker is shaken, so that the stability of the structure is improved;
3. the slapping mechanism arranged at the bottom of the thermostatic bath is beneficial to slapping the supporting plate to enable the supporting plate to generate proper shaking, and the slapping mechanism alternatively slaps two sides of the bottom of the supporting plate to be beneficial to stable shaking of the supporting plate and improving the stability and controllability of the structure;
4. the slapping mechanism slaps the rotating supporting plate at the bottom of the thermostatic bath, so that media can be stirred in the thermostatic bath, the media in the thermostatic bath can be uniformly distributed, the uniformity of the temperature in the thermostatic bath can be improved, and the disintegration effect can be improved.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a schematic structural view of the disintegration chamber of the present invention in one state.
Fig. 3 is a schematic structural view of the disintegration chamber of the present invention in another state.
Fig. 4 is a schematic structural diagram of a support plate.
Fig. 5 is a schematic view of the flapper mechanism.
In the drawings: 1. a thermostatic bath; 2. a chassis; 3. a lifting mechanism; 4. a test tube rack; 5. a disintegration chamber; 6. a support plate; 7. a beaker; 8. locking a ring; 9. a slapping mechanism; 10. a first rotating shaft; 11. a second rotating shaft; 12. a first eccentric wheel; 13. a second eccentric wheel; 14. a first elastic part; 15. a second elastic part; 16. a flange portion; 17. a limiting part; 18. rotating the rod; 19. a separator.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Example 1: as shown in fig. 1 to 5, an intelligent disintegration tester for analysis and detection includes a thermostatic bath 1, a chassis 2, an elevating mechanism 3 and a test tube rack 4; a disintegration chamber 5 is arranged below the test tube rack 4; a supporting plate 6 is arranged in the disintegration chamber 5; a beaker 7 is placed on the supporting plate 6; the supporting plate 6 is provided with a locking ring 8; the locking ring locks the beaker 7; the test tube rack 4 is movably arranged in the beaker 7 up and down; two sides of the supporting plate 6 are hinged with two side walls of the disintegration chamber 5; the bottom of the thermostatic bath 1 is provided with a slapping mechanism 9; the slapping mechanism 9 alternatively slaps two sides of the bottom of the supporting plate 6; in the embodiment, the thermostatic bath 1, the chassis 2, the lifting mechanism 3 and the test tube rack 4 are made of conventional materials with certain mechanical strength and have conventional structures, and any reasonable structure and installation mode can be selected according to needs; in the embodiment, the test tube is detachably placed on the test tube rack 4, the lifting mechanism 3 drives the test tube rack 4 and the test tube to be movably arranged in the beaker 7, and any reasonable lifting mechanism 3 can be selected according to the requirement; in this embodiment, the supporting plate 6 is made of a conventional material with a certain mechanical strength, and any reasonable material can be selected according to the requirement; in the embodiment, the locking ring 8 on the supporting plate 6 adopts a conventional locking mechanism, and any reasonable locking ring 8 can be selected according to the requirement; in the embodiment, the locking ring 8 is fixed on the supporting plate 6 in a conventional fixing way; in the embodiment, a proper amount of temperature control media is filled in the thermostatic bath 1, and any reasonable medium can be selected according to needs; in the embodiment, the force and frequency for the slapping mechanism 9 to slap the supporting plate 6 are reasonably set according to needs, so that the proper disintegration can be favorably carried out; in this embodiment, the flapping mechanism 9 can be controlled by a connection controller, and any reasonable controller and connection mode can be selected according to requirements; in this embodiment, the controller selects a conventional commercially available numerical control PLC system.
The support plate 6 in the disintegration chamber 5 is used for placing and fixing the beaker 7, and after two sides of the support plate 6 are hinged with two side walls of the disintegration chamber 5, the support plate 6 is favorable for driving the beaker 7 on the support plate 6 to generate proper shaking after receiving the flapping shaking of the bottom flapping mechanism 9, so that the gastric peristalsis environment can be simulated simply, the mixing contact of the medicine and the medium in the beaker 7 is favorable, and the disintegration effect is improved; the locking ring 8 arranged on the supporting plate 6 is beneficial to fixing the beaker 7 placed on the supporting plate 6, and is beneficial to stably placing the beaker 7 when the supporting plate 6 shakes, thereby being beneficial to improving the stability of the structure; the slapping mechanism 9 arranged at the bottom of the thermostatic bath 1 is beneficial to slapping the supporting plate 6 to enable the supporting plate 6 to generate proper shaking, and the slapping mechanism 9 alternatively slaps two sides of the bottom of the supporting plate 6, so that the supporting plate 6 is beneficial to stably shaking, and the stability and controllability of the structure are improved; the slapping mechanism 9 slaps the rotating supporting plate 6 at the bottom of the thermostatic bath 1, which is beneficial to stirring media in the thermostatic bath 1, is beneficial to enabling the media in the thermostatic bath 1 to be uniformly distributed, is beneficial to improving the uniformity of the temperature in the thermostatic bath 1, and is beneficial to improving the disintegration effect.
The flapping mechanism 9 comprises a first rotating shaft 10 and a second rotating shaft 11 which are arranged side by side; a first eccentric wheel 12 is arranged on the first rotating shaft 10; a second eccentric wheel 13 is arranged on the second rotating shaft 11; when the first rotating shaft 10 and the second rotating shaft 11 are driven by the driver to rotate, the first eccentric wheel 12 and the second eccentric wheel 13 alternately slap two sides of the bottom of the supporting plate 6; in this embodiment, the first rotating shaft 10 and the second rotating shaft 11 can be driven by conventional commercially available stepping motors, and any reasonable motor model and structure can be selected as required, in this embodiment, the motor output shaft is connected with the first rotating shaft 10 or the second rotating shaft 11 by a conventional commercially available coupler; in the embodiment, the motor is arranged on the side wall of the thermostatic bath 1 and is electrically connected to an external power supply and a numerical control system; in this embodiment, the two ends of the first rotating shaft 10 and the second rotating shaft 11 are respectively erected on the side wall of the thermostatic bath 1 by using conventional commercially available bearing pieces, and any reasonable bearing piece can be selected according to needs; in this embodiment, the first eccentric wheel 12 and the second eccentric wheel 13, and the first rotating shaft 10 and the second rotating shaft 11 are made of conventional materials with certain mechanical strength, and any reasonable material and connection mode can be selected according to requirements; in the embodiment, the first eccentric wheels 12 are arranged on the first rotating shaft 10 at reasonable intervals, and the second eccentric wheels 13 are arranged on the second rotating shaft 11 at reasonable intervals; in this embodiment, the first rotating shaft 10 and the second rotating shaft 11 are arranged side by side, which is beneficial to the first eccentric wheel 12 and the second eccentric wheel 13 acting on two sides of the bottom of the supporting plate 6 alternately when the first rotating shaft 10 and the second rotating shaft 11 rotate, so as to be beneficial to the supporting plate 6 generating stable vibration, the beaker 7 on the supporting plate 6 stably shaking, and the disintegration is facilitated; in this embodiment, when the first eccentric wheel 12 or the second eccentric wheel 13 strikes a certain side of the bottom of the supporting plate 6, the supporting plate 6 is tilted upward at a proper height in the side direction in a hinge connection mode of the supporting plate 6, and the supporting plate can be reset by gravity along with the separation of the first eccentric wheel 12 or the second eccentric wheel 13, so that the supporting plate 6 is favorably prevented from generating proper vibration. When the first and second rotary shafts 10, 11 rotate in the thermostatic bath 1, the first and second eccentrics 12, 13 also serve to stir the medium in the thermostatic bath 1, which is advantageous for improving the uniformity of the temperature in the thermostatic bath 1.
The first rotating shaft 10 and the second rotating shaft 11 rotate in opposite directions; in this embodiment, the first rotating shaft 10 and the second rotating shaft 11 rotate in opposite directions, and may rotate in opposite directions or in opposite directions, which is beneficial to improve the stirring effect on the medium in the thermostatic bath 1 while the first eccentric wheel 12 and the second eccentric wheel 13 alternately slap the bottom plate.
A first elastic part 14 is arranged at the end part of the first eccentric wheel 12; a second elastic part 15 is arranged at the end part of the second eccentric wheel 13; the end surfaces of the first elastic part 14 and the second elastic part 15 are arc surfaces; in this embodiment, the first elastic portion 14 and the second elastic portion 15 are both made of conventional materials with certain mechanical strength and elastic deformation force, and any reasonable material can be selected according to the requirement; in this embodiment, the first elastic portion 14 and the second elastic portion 15 may be connected to the ends of the first eccentric wheel 12 and the second eccentric wheel 13 through conventional commercially available elastic members, which is beneficial to generate a suitable deformation space at the ends of the first eccentric wheel 12 and the second eccentric wheel 13 and is beneficial to improve the flexibility of slapping the blade 6; meanwhile, the damping and buffering are facilitated, and the service cycle and the structural stability are facilitated to be improved; in this embodiment, the end portions of the first elastic portion 14 and the second elastic portion 15 are arc surfaces, which is beneficial to reducing scratches on the lower surface of the supporting plate 6 when the supporting plate 6 is flapped, and is beneficial to improving flexibility when the supporting plate is flapped; is beneficial to improving the service cycle and the stability of the structure.
Rotating rods 18 are also oppositely arranged on two sides of the supporting plate 6; the rotating rod 18 is rotatably connected with the side wall of the disintegration chamber 5; in this embodiment, the rotating rod 18 is made of a conventional material having a certain mechanical strength, and any reasonable material can be selected according to the requirement; in this embodiment, one end of the rotating rod 18 is fixedly connected with the circumferential surface of the supporting plate 6, which is beneficial to driving the supporting plate 6 to turn over; in this embodiment, the other end of the rotating rod 18 is connected with the side wall of the disintegration chamber 5 by a conventional rotating connection method, for example, a conventional commercially available shaft pin member is adopted, or a rotating groove is formed on the side wall of the disintegration chamber 5 corresponding to the rotating rod 18 and connected with the rotating rod 18 by a conventional commercially available bearing member; any reasonable rotary connection mode can be selected according to the requirement; the rotating rod 18 is beneficial to the supporting plate 6 to flexibly rotate by a certain angle when receiving the slapping, is beneficial to improving the stability and flexibility of the vibration of the supporting plate 6, is beneficial to improving the stability and flexibility of the shaking of the beaker 7, and is beneficial to improving the disintegration effect.
A partition plate 19 is arranged in the thermostatic bath 1; the partition plate 19 divides more than two disintegration chambers 5 in the thermostatic bath 1; a supporting plate 6 is correspondingly arranged in each disintegration chamber 5; in this embodiment, the partition plate 19 is made of a conventional material having a certain mechanical strength, and any reasonable material can be selected as required; in this embodiment, more than two disintegration chambers 5 are provided in the thermostatic bath 1, which is advantageous for improving disintegration efficiency, and the slapping mechanism 9 can slap the supporting plates 6 in the plurality of disintegration chambers 5 at the same time, which is advantageous for improving slapping efficiency.
Two sides of the partition plate 19 are connected with the inner wall of the thermostatic chamber; the lower end edge of the partition plate 19 is positioned above the flapping mechanism 9; two side walls of the partition plate 19 are fixedly connected with the side wall of the thermostatic bath 1 in a conventional fixed connection mode respectively, and any reasonable fixed connection mode can be selected according to requirements; in the embodiment, the edge of the lower end of the partition plate 19 is not connected with the bottom of the thermostatic bath 1, so that the thermostatic media can be communicated among the disintegrating chambers 5, and the slapping mechanisms 9 can slap the plurality of supporting plates 6 at the same time; in this embodiment, the first rotating shaft 10 and the second rotating shaft 11 of the flapping mechanism 9 are appropriately spaced, the first eccentric wheel 12 is appropriately spaced on the first rotating shaft 10, and the second eccentric wheel 13 is appropriately spaced on the second rotating shaft 11, so that reasonable selection and layout can be realized as required, and the flapping vibration effect on the supporting plate 6 can be improved and controlled.
Although the invention has been described herein with reference to a number of illustrative embodiments thereof, it should be understood that numerous other modifications and embodiments can be devised by those skilled in the art that will fall within the spirit and scope of the principles of this invention. More specifically, various variations and modifications are possible in the component parts and/or arrangements of the subject combination arrangement within the scope of the disclosure, the drawings and the appended claims. In addition to variations and modifications in the component parts and/or arrangements, other uses will also be apparent to those skilled in the art.
Claims (8)
1. An intelligent disintegration tester for analysis and detection comprises a thermostatic bath (1), a case (2), a lifting mechanism (3) and a test tube rack (4); the method is characterized in that: a disintegration chamber (5) is arranged below the test tube rack (4); a supporting plate (6) is arranged in the disintegration chamber (5); a beaker (7) is placed on the supporting plate (6); a locking ring (8) is arranged on the supporting plate (6); the beaker (7) is locked by the locking ring (8); the test tube rack (4) is movably arranged in the beaker (7) up and down; two sides of the supporting plate (6) are hinged with two side walls of the disintegration chamber (5); the bottom of the thermostatic bath (1) is provided with a slapping mechanism (9); the flapping mechanisms (9) alternately flap the two sides of the bottom of the supporting plate (6).
2. The intelligent disintegration tester for analysis and detection according to claim 1, wherein: the flapping mechanism (9) comprises a first rotating shaft (10) and a second rotating shaft (11) which are arranged side by side; a first eccentric wheel (12) is arranged on the first rotating shaft (10); a second eccentric wheel (13) is arranged on the second rotating shaft (11); when the first rotating shaft (10) and the second rotating shaft (11) are driven by the driver to rotate, the first eccentric wheel (12) and the second eccentric wheel (13) alternately flap two sides of the bottom of the supporting plate (6).
3. The intelligent disintegration tester for analysis and detection according to claim 2, wherein: the rotating directions of the first rotating shaft (10) and the second rotating shaft (11) are opposite.
4. The intelligent disintegration tester for analysis and detection according to claim 2, wherein: a first elastic part (14) is arranged at the end part of the first eccentric wheel (12); a second elastic part (15) is arranged at the end part of the second eccentric wheel (13); the end surfaces of the first elastic part (14) and the second elastic part (15) are arc surfaces.
5. The intelligent disintegration tester for analysis and detection according to claim 1, wherein: two sides of the supporting plate (6) extend outwards to form flange parts (16); a limiting part (17) is arranged on the inner wall of the disintegration chamber (5) corresponding to the flange part (16); the limiting part (17) is used for limiting the tilting height of the supporting plate (6).
6. The intelligent disintegration tester for analysis and detection according to claim 4, wherein: rotating rods (18) are also oppositely arranged on two sides of the supporting plate (6); the rotating rod (18) is rotatably connected with the side wall of the disintegration chamber (5).
7. The intelligent disintegration tester for analysis and detection according to claim 1, wherein: a partition plate (19) is arranged in the thermostatic bath (1); the partition plate (19) divides more than two disintegration chambers (5) in the thermostatic bath (1); each disintegration chamber (5) is internally and correspondingly provided with a supporting plate (6).
8. The intelligent disintegration tester for analysis and detection according to claim 7, wherein: two sides of the partition plate (19) are connected with the inner wall of the thermostatic chamber; the lower end edge of the partition plate (19) is positioned above the slapping mechanism (9).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022846233.7U CN214703564U (en) | 2020-12-01 | 2020-12-01 | Intelligent disintegration tester for analysis and detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022846233.7U CN214703564U (en) | 2020-12-01 | 2020-12-01 | Intelligent disintegration tester for analysis and detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214703564U true CN214703564U (en) | 2021-11-12 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022846233.7U Active CN214703564U (en) | 2020-12-01 | 2020-12-01 | Intelligent disintegration tester for analysis and detection |
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| Country | Link |
|---|---|
| CN (1) | CN214703564U (en) |
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2020
- 2020-12-01 CN CN202022846233.7U patent/CN214703564U/en active Active
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| GR01 | Patent grant | ||
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| CP03 | Change of name, title or address |
Address after: Floor 4-5, Building 1, No. 1628, East Section of Shenzhou Road, Demonstration Zone, Jiaozuo City, Henan Province, 454000 Patentee after: Jiaozuo Huaiyao Biotechnology Co.,Ltd. Address before: 454002 room 2, building 1, no.1628, east section of Shenzhou Road, Jiaozuo demonstration area, Henan Province (in the hospital of Jiaozuo Mingren Pharmaceutical Biotechnology Co., Ltd.) Patentee before: Jiaozuo bailunsi Biotechnology Co.,Ltd. |
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| CP03 | Change of name, title or address |