CN214582186U - Thermal cycle drying device for biological samples - Google Patents
Thermal cycle drying device for biological samples Download PDFInfo
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- CN214582186U CN214582186U CN202120439343.3U CN202120439343U CN214582186U CN 214582186 U CN214582186 U CN 214582186U CN 202120439343 U CN202120439343 U CN 202120439343U CN 214582186 U CN214582186 U CN 214582186U
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Abstract
The utility model relates to a thermal cycle drying device for biological sample belongs to drying device technical field. The thermal circulation drying device comprises a hot air circulation drying chamber, an air inlet pipe and an exhaust pipe. In the using process of the thermal cycle drying device, a gas dryer firstly carries out pre-drying treatment on gas entering a hot air cycle drying chamber; then the gas is filtered through a gas filtering pipe; the filtered gas enters a hot air blower, the hot air blower heats the gas and blows the gas into a hot air circulation drying chamber, and in the hot air circulation drying chamber, hot air passes through an air inlet, a gas guide air channel and an air outlet of each hollow partition plate from bottom to top in sequence under the action of the hollow partition plates, so that the hot air alternately flows layer by layer from bottom to top; thereby achieving the purpose of accelerating concentration and drying of the liquid in the tube. In a word, this a thermal cycle drying device for biological sample structural design is reasonable, is fit for handling simultaneously big sample concentration drying in batches, and concentration drying is safe and reliable, is fit for using widely.
Description
Technical Field
The utility model relates to a thermal cycle drying device for biological sample belongs to drying device technical field.
Background
Biological samples in general need to be concentrated in dry powder form for ease of transport and long-term storage. The common biological agent samples such as chemically synthesized oligonucleotides, DNA extracted from plasmids, genomic DNA extracted from blood or plant samples and the like need to be concentrated into dry powder for long-term storage and transportation, and the samples of the types generally have the characteristic of multiple types of samples processed simultaneously.
The existing common biological sample concentration drying methods comprise a vacuum centrifugal drying method, a low-temperature freeze-drying method, a hot air nitrogen blowing method and the like, but all have some operational disadvantages; the vacuum centrifugal drying method is the most common method in the prior art, and has the disadvantages of complicated operation and high labor cost; the time period for drying once by the low-temperature freeze-drying method is longer, and the equipment cost is high; the current equipment design of the hot air nitrogen blowing method is still imperfect and is only suitable for drying and concentrating a small amount of samples; therefore, the current methods cannot solve the problem of simultaneous drying of different samples in large quantities.
SUMMERY OF THE UTILITY MODEL
In order to overcome the defect that exists among the background art, the utility model provides a technical scheme that its technical problem adopted is: the utility model provides a thermal cycle drying device for biological sample, includes heated air circulation drying chamber, air-supply line and exhaust pipe, be fixed with a plurality of cavity baffles in the heated air circulation drying chamber, the one end bottom of cavity baffle is equipped with the air intake, the other end top of cavity baffle is equipped with the air outlet, the middle part of cavity baffle is gaseous water conservancy diversion wind channel, gaseous water conservancy diversion wind channel is with air intake and air outlet intercommunication, the air-supply line is linked together with the heated air circulation drying chamber of bottommost cavity baffle below, the exhaust pipe is linked together with the heated air circulation drying chamber of topmost cavity baffle top, be fixed with adjustable temperature heating base on the cavity baffle, be equipped with the sample frame in the adjustable temperature heating base, be close to the heated air circulation drying chamber on the air-supply line and be equipped with air heater, gas filter tube and gas dryer in proper order.
Preferably, the hollow partition plate is obliquely fixed in the hot air circulation drying chamber.
The distance between two adjacent hollow partition plates is preferably 20-30 cm.
Preferably, the drying agent in the gas dryer is allochroic silica gel or calcium chloride.
Preferably, the air heater can heat the drying gas to 68-72 ℃, and the working temperature of the temperature-adjustable heating base is 68-72 ℃.
The utility model designs a thermal cycle drying device for biological samples, in the using process of the thermal cycle drying device for biological samples, a gas dryer firstly carries out pre-drying treatment on the gas entering a hot air cycle drying chamber; then the gas is filtered through a gas filtering pipe; the filtered gas enters a hot air blower, the hot air blower heats the gas and blows the gas into a hot air circulation drying chamber, and in the hot air circulation drying chamber, hot air passes through an air inlet, a gas guide air channel and an air outlet of each hollow partition plate from bottom to top in sequence under the action of the hollow partition plates, so that the hot air alternately flows layer by layer from bottom to top; the adjustable temperature heating base is fixed on the hollow partition plate, a sample rack is arranged in the adjustable temperature heating base, a sample to be concentrated and dried is placed in the sample rack, the adjustable temperature heating base can heat the sample in the sample rack, and meanwhile, hot air flows in a unidirectional mode near the orifice of the sample, so that the aim of accelerating concentration and drying of liquid in the tube is fulfilled; last hot-air is discharged through the exhaust pipe, and the accessible exhaust pipe discharges and appoints the region, contains harm volatile gas to the drying when, can arrange to exhaust treatment device through the exhaust pipe and handle tail gas. The utility model relates to a thermal cycle drying device for biological sample can be used to the drying of chemical synthesis oligonucleotide, the batch drying operation of the plasmid DNA of extraction and the synthetic DNA that obtains of gene to and the cryoconcentration drying process that can be used to multiple compound micromolecule. In a word, this a thermal cycle drying device for biological sample structural design is reasonable, is fit for handling simultaneously that a large amount of samples concentrate the drying, and the sample that has accomplished the drying and add newly can be got at any time and put. The ultraviolet absorption value of the dried sample is retested by using the sample dried by the thermal cycle drying device, the deviation of the product amount is less than 2 percent, the sample is not lost, and the concentration and drying are safe and reliable; this thermal cycle drying device can set for the temperature according to concrete demand and carry out the drying, is fit for using widely.
Drawings
The present invention will be further explained with reference to the drawings and examples.
Fig. 1 is a schematic structural diagram of a thermal cycle drying device for biological samples according to the present invention;
FIG. 2 is a schematic diagram of the internal structure of a thermal cycle drying device for biological samples according to the present invention;
FIG. 3 is a partial cross-sectional view of the interior of a thermal cycle drying apparatus for biological samples in accordance with the present invention;
wherein, 1, a hot air circulation drying chamber; 2. an air inlet pipe; 3. an exhaust duct; 4. a hot air blower; 5. a gas filtering pipe; 6. a gas dryer; 7. a hollow partition plate; 8. an air inlet; 9. a gas diversion air duct; 10. an air outlet; 11. a temperature-adjustable heating base; 12. and (4) a sample holder.
Detailed Description
The present invention will now be described in further detail with reference to the accompanying drawings. The attached drawings are simplified schematic diagrams, and merely illustrate the basic structure of the present invention in a schematic manner, and thus show only the components related to the present invention.
In a first specific embodiment, referring to fig. 1-3, a thermal cycle drying device for biological samples includes a thermal cycle drying chamber 1, an air inlet pipe 2 and an air outlet pipe 3, wherein a plurality of hollow partition plates 7 are fixed in the thermal cycle drying chamber 1, an air inlet 8 is arranged at the bottom of one end of each hollow partition plate 7, an air outlet 10 is arranged at the top of the other end of each hollow partition plate 7, a gas guide air duct 9 is arranged in the middle of each hollow partition plate 7, the air inlet 8 and the air outlet 10 are communicated by the gas guide air duct 9, the air inlet pipe 2 is communicated with the thermal cycle drying chamber 1 below the bottommost hollow partition plate 7, the air outlet pipe 3 is communicated with the thermal cycle drying chamber 1 above the topmost hollow partition plate 7, an adjustable temperature heating base 11 is fixed on the hollow partition plate 7, and a sample holder 12 is arranged in the adjustable temperature heating base 11, be close to heated air circulation drying chamber 1 on the air-supply line 2 and be equipped with air heater 4, gas filtration pipe 5 and gas dryer 6 in proper order, the slope of empty baffle 7 is fixed in heated air circulation drying chamber 1, and the distance between two adjacent cavity baffles 7 is 25 centimetres, the drier in the gas dryer 6 is allochroic silica gel or calcium chloride, air heater 4 can heat drying gas to 70 degrees centigrade, the operating temperature of adjustable temperature heating base 11 is 70 degrees centigrade.
The utility model designs a thermal cycle drying device for biological samples, in the using process of the thermal cycle drying device for biological samples, a gas dryer 6 firstly carries out pre-drying treatment on the gas entering a hot air cycle drying chamber 1; then the gas is filtered through a gas filtering pipe 5; the filtered gas enters a hot air blower 4, the hot air blower 4 heats the gas and blows the gas into a hot air circulation drying chamber 1, and in the hot air circulation drying chamber 1, hot air passes through an air inlet 8, a gas guide air duct 9 and an air outlet 10 of each hollow partition plate 7 from bottom to top in sequence under the action of the hollow partition plates 7, so that the hot air alternately flows layer by layer from bottom to top; an adjustable temperature heating base 11 is fixed on the hollow partition 7, a sample rack 12 is arranged in the adjustable temperature heating base 11, a sample to be concentrated and dried is placed in the sample rack 12, the adjustable temperature heating base 11 can heat the sample in the sample rack 12, and meanwhile, hot air flows in a unidirectional mode near the orifice of the sample pipe, so that the aim of accelerating concentration and drying of liquid in the pipe is fulfilled; last hot-air is discharged through exhaust pipe 3, and accessible exhaust pipe 3 discharges to the appointed area, contains harm volatile gas to the drying when, can arrange to exhaust treatment device through exhaust pipe 3 and handle tail gas. The utility model relates to a thermal cycle drying device for biological sample can be used to the drying of chemical synthesis oligonucleotide, the batch drying operation of the plasmid DNA of extraction and the synthetic DNA that obtains of gene to and the cryoconcentration drying process that can be used to multiple compound micromolecule. In a word, this a thermal cycle drying device for biological sample structural design is reasonable, is fit for handling simultaneously that a large amount of samples concentrate the drying, and the sample that has accomplished the drying and add newly can be got at any time and put. The ultraviolet absorption value of the dried sample is retested by using the sample dried by the thermal cycle drying device, the deviation of the product amount is less than 2 percent, the sample is not lost, and the concentration and drying are safe and reliable; this thermal cycle drying device can set for the temperature according to concrete demand and carry out the drying, is fit for using widely.
It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications can be made without departing from the scope of the invention.
Claims (5)
1. The utility model provides a thermal cycle drying device for biological sample, includes heated air circulation drying chamber (1), air-supply line (2) and exhaust pipe (3), its characterized in that: the hot air circulation drying chamber is characterized in that a plurality of hollow partition plates (7) are fixed in the hot air circulation drying chamber (1), an air inlet (8) is formed in the bottom of one end of each hollow partition plate (7), an air outlet (10) is formed in the top of the other end of each hollow partition plate (7), a gas guide air channel (9) is formed in the middle of each hollow partition plate (7), the gas guide air channel (9) communicates the air inlet (8) with the air outlet (10), an air inlet pipe (2) is communicated with the hot air circulation drying chamber (1) below the bottommost hollow partition plate (7), an exhaust pipe (3) is communicated with the hot air circulation drying chamber (1) above the topmost hollow partition plate (7), an adjustable temperature heating base (11) is fixed on each hollow partition plate (7), a sample rack (12) is arranged in the adjustable temperature heating base (11), and a hot air fan (4) and a hot air blower (4) are sequentially arranged on the air inlet pipe (2) close to the hot air circulation drying chamber (1), A gas filtering pipe (5) and a gas drier (6).
2. The thermal cycler drying apparatus for biological samples of claim 1, wherein: the hollow partition plate (7) is obliquely fixed in the hot air circulation drying chamber (1).
3. The thermal cycler drying apparatus for biological samples of claim 1, wherein: the distance between two adjacent hollow partition plates (7) is 20-30 cm.
4. The thermal cycler drying apparatus for biological samples of claim 1, wherein: and the drying agent in the gas dryer (6) is allochroic silica gel or calcium chloride.
5. The thermal cycler drying apparatus for biological samples of claim 4, wherein: the air heater (4) can heat dry gas to 68-72 ℃, and the working temperature of the temperature-adjustable heating base (11) is 68-72 ℃.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120439343.3U CN214582186U (en) | 2021-03-01 | 2021-03-01 | Thermal cycle drying device for biological samples |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202120439343.3U CN214582186U (en) | 2021-03-01 | 2021-03-01 | Thermal cycle drying device for biological samples |
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| CN214582186U true CN214582186U (en) | 2021-11-02 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114485075A (en) * | 2022-02-14 | 2022-05-13 | 黑龙江中医药大学 | Hot air circulation drying device in traditional Chinese medicine preparation process |
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2021
- 2021-03-01 CN CN202120439343.3U patent/CN214582186U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114485075A (en) * | 2022-02-14 | 2022-05-13 | 黑龙江中医药大学 | Hot air circulation drying device in traditional Chinese medicine preparation process |
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