CN214566868U - Clinical proteomics plasma sample sampling kit - Google Patents

Abstract

The utility model relates to a clinical proteomics plasma sample sampling kit, which comprises an instruction book storage box, a sample storage box and a reagent tube storage box; a reagent tube and a first bearing structure for fixing the reagent tube are arranged in the reagent tube storage box, and a Buffer A reagent is sealed in the reagent tube; and a low-temperature ice bag and a second bearing structure for fixing the reagent tube are arranged in the sample storage box. The utility model discloses store the box integration with relevant explanation of sampling, reagent pipe, Buffer A reagent and low temperature sample and be a sampling suit, sample provider can contrast the sampling explanation, puts into the reagent pipe that contains Buffer A reagent after correctly handling the plasma of gathering, puts into the sample storage box that has the low temperature ice bag again, then directly sends the sample storage box to detection mechanism, and whole process can guarantee that the sample is effective, and is stable, practices thrift simultaneously and communicates with the cost.

Description

Clinical proteomics plasma sample sampling kit

Technical Field

The utility model relates to a clinical proteomics sampling technology field, concretely relates to clinical proteomics plasma sample sampling kit.

Background

Proteomics (Proteomics) refers to the discipline of large-scale, high-throughput study of a full set of proteins expressed in a cell, tissue or species. The mass spectrometry technology is the most important technical means in the proteomics research strategy, and in recent years, the proteomics research based on the mass spectrometry technology is increasingly applied to the screening of biomarkers of clinical etiology, diagnosis, treatment and prognosis. The collection, test and analysis of proteomics samples are often completed by different mechanisms, the collection and sample feeding processes of clinical samples are crucial to the accuracy of the later detection process and detection results, blood cells need to be separated and stored reasonably in time after the blood samples are collected, the freshness of the samples needs to be guaranteed in the sample feeding process, and the samples cannot be used due to damage, pollution, deterioration and the like. The existing detection mechanism needs to be closely communicated with a sample provider before obtaining a sample to ensure that the sampling process meets the specification, however, the collection of clinical samples often needs the cooperation of nurses, clinical laboratories and clinicians, so that the reasonable collection of plasma samples cannot be well completed only through communication, and the development of analysis and detection work is not facilitated.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a clinical proteomics plasma sample sampling kit, the sample provider of being convenient for carries out the collection of the plasma sample of standardization and timely reasonable storage and transportation, practices thrift and communicates the procedure.

The utility model provides a scheme that above-mentioned technical problem adopted is:

a clinical proteomics plasma sample sampling kit comprises an instruction book storage box, a sample storage box and a reagent tube storage box; a reagent tube and a first bearing structure for fixing the reagent tube are arranged in the reagent tube storage box, and a Buffer A reagent is sealed in the reagent tube; and a low-temperature ice bag and a second bearing structure for fixing the reagent tube are arranged in the sample storage box.

Preferably, the instruction storage box, the sample storage box and the reagent tube storage box are detachably connected in sequence.

Preferably, the instruction storage box, the sample storage box and the reagent tube storage box are stacked in the outer packaging box from top to bottom.

Preferably, the side face of the instruction book storage box is opened, and a card and/or a manual are arranged inside the instruction book storage box.

Preferably, an openable upper cover is arranged at the top of the sample storage box, and the upper cover is connected with the reagent box through a coded lock.

Preferably, the inner wall of the sample storage box is covered with an insulating layer and a waterproof layer.

Preferably, the upper surface of the sample storage box is provided with a lifting lug.

Preferably, the number of reagent tubes that can be carried in the first and second carrier structures is the same.

The utility model discloses store the box integration with relevant explanation of sampling, reagent pipe, Buffer A reagent and sample and be a sampling suit, the sample provider can contrast the sampling explanation, puts into the reagent pipe that contains Buffer A reagent after correctly handling the plasma of gathering, puts into the sample storage box that has the low temperature ice bag again, then directly stores the box with the sample and sends detection mechanism to, and whole process can guarantee that the sample is effective, and is stable, practices thrift simultaneously and communicates the cost.

Drawings

Figure 1 is a schematic structural diagram of the clinical proteomics plasma sample sampling kit of the present invention, example 1;

FIG. 2 is an expanded view of the inner side of the outer packing box of embodiment 1 of the present invention;

FIG. 3 is an expanded view of the outer packing box of embodiment 1 of the present invention;

fig. 4 is an expanded view of the book storage case according to embodiment 1 of the present invention;

fig. 5 is an expanded view of a second bearing structure according to embodiment 1 of the present invention;

fig. 6 is another development view of a second bearing structure according to embodiment 1 of the present invention;

fig. 7 is a schematic structural view of embodiment 2 of the present invention.

The figures in the drawings are labeled as:

1, packaging the mixture in an outer packaging box; 2, reagent tubes; 3, a first bearing structure; 4, holes; 5, a sample storage box; 6, lifting the ears; 7, a low-temperature ice bag; 8, a second bearing structure; 9, a specification storage box; 10, a reagent tube storage box; 11, an upper cover; 12, a coded lock; 13, a magnet.

Detailed Description

For better understanding of the present invention, the following examples are further illustrative of the present invention, but the present invention is not limited to the following examples.

Example 1

As shown in fig. 1, a clinical proteomics plasma sample sampling kit comprises an external packing box 1, wherein the internal space of the external packing box 1 is sequentially divided into an instruction storage area, a sample storage area and a reagent tube storage area from top to bottom.

The external packing box 1 is in a cuboid shape with an openable structure, and includes but is not limited to a hinged box body and box cover structure, a split buckled box body and box cover structure, and a detachable cuboid structure formed by folding a hard board (as shown in fig. 2 and 3). The box body needs to be waterproof, and when a hardboard is adopted as a box body material, waterproof layers need to be covered on the inner surface and the outer surface.

The reagent tube storage area can be internally provided with a reagent tube storage box, and can also be directly taken as the bottom of the external packing box 1, the latter is preferably selected in the embodiment, the appearance of the first bearing structure 3 is cuboid, the length and the width are matched with the inner wall of the external packing box 1, the upper surface of the first bearing structure is provided with a plurality of holes 4, and the reagent tubes 2 are inserted into the holes 4 for fixation. The first supporting structure 3 may be a plastic or foam integrally formed structure, or may be formed by folding a piece of cardboard, or may be formed by inserting a piece of cardboard into a grid structure, as shown in fig. 5 and 6. The reagent tube 2 is sealed with Buffer a reagent, which is a sample Buffer commonly used in proteomics testing and can be formulated according to the testing requirements, and the basic requirement is to stabilize the plasma sample (e.g. 1% SDC/TCEP/CAA/Tris-HCl).

Be provided with sample storage box 5 in the sample storage area, sample storage box 5 is the cuboid shape of structure that can open and shut, including but not limited to the collapsible cuboid structure that articulated box body and lid structure, components of a whole that can function independently buckled box body and lid structure, hardboard are folded and are formed. The length and the width of the sample storage box 5 are matched with the inner wall of the outer packing box 1, and the top of the sample storage box is provided with a lifting lug 6 which is convenient to take out from the outer packing box 1. The inner wall of the sample storage box 5 covers the heat-insulating layer, the box body needs to be waterproof, and when a hardboard is adopted as a box body material, the inner layer and the outer layer need to be coated with waterproof layers. The bottom of the sample storage box 5 is provided with a low-temperature ice bag 7, the upper portion of the low-temperature ice bag 7 is provided with a second bearing structure 8 for fixing the reagent tube 2, the second bearing structure 8 is in a cuboid shape, the upper surface of the second bearing structure is provided with a plurality of holes 4, an integrally formed structure is preferably adopted, such as plastic and foam, the second bearing structure can also be formed by folding a waterproof hard board, the length and the width of the second bearing structure are matched with the sample storage box 5 walls, the reagent tube 2 can be inserted into the holes 4, the holes 4 in the first bearing structure 3 and the second bearing structure 8 are fixed, and the structures of the holes 4 are the same.

The instruction book storage area is internally provided with an instruction book storage box 9 for storing cards and/or manuals, such as recommended sampling processes, kit use instructions, clinical proteome project design self-checking tables, blood sampling prompt cards and the like. The side of the instruction book storage box 9 is opened, so that the manual or the card inside can be taken out conveniently, and the lifting lug 6 is arranged on the upper surface, so that the instruction book storage box can be taken out conveniently from the reagent kit. The specification storage box 9 can be made of folded hardboard with waterproof surface, and has a cuboid shape, as shown in fig. 4, and the length and the width are preferably matched with the inner wall of the outer packing box 1.

Waterproof heat-preservation interlayers are arranged among adjacent areas in the instruction book storage area, the sample storage area and the reagent tube 2 storage area.

In specific use, a sampler takes out the instruction storage box 9 in the detection box, uses purple blood collection tubes (EDTA) to perform venipuncture collection of blood samples according to the instruction of a control instruction, centrifuges the blood collection tubes at room temperature of 2000 Xg for 10 minutes within 30 minutes, takes supernatant blood plasma in a centrifuge tube, centrifuges the plasma centrifuge tube at room temperature of 2500 Xg for 15 minutes, and takes the supernatant blood plasma in a new centrifuge tube. Taking out the reagent tube 2, adding 20 mu L of plasma sample into the reagent tube, dissolving the plasma sample in the Buffer A solvent, and uniformly mixing; under the condition of ensuring the refrigeration of the low-temperature ice bag 7, a plasma sample tube dissolved in Buffer A is inserted into the first bearing structure 3 in the sample storage box 5, and then the sample storage box 5 is sealed and sent to the detection mechanism. Wherein corresponding prompt card specifications and the like can be transferred among different operators along with the blood sample, so that the operators can operate according to the prompt.

Example 2

A clinical proteomics plasma sample sampling kit, as shown in fig. 7, comprising an instruction storage box 9, a sample storage box 5, and a reagent tube storage box 10. The contact surfaces of the specification storage box 9, the sample storage box 5 and the reagent tube storage box 10 are respectively fixed with a magnet 13, and the three box bodies are detachably connected through magnetic attraction.

The top of the sample storage box 10 is provided with an openable upper cover 11, the upper cover 11 is connected with the reagent box through a coded lock 12, and the surface of the upper cover is provided with a lifting lug.

While the foregoing is directed to the preferred embodiment of the present invention, it will be understood that the invention is not limited thereto, and that various modifications and changes can be made by those skilled in the art without departing from the principles of the invention.

Claims (8)

1. A clinical proteomics plasma sample sampling kit is characterized by comprising an instruction book storage box, a sample storage box and a reagent tube storage box; a reagent tube and a first bearing structure for fixing the reagent tube are arranged in the reagent tube storage box, a Buffer A reagent is sealed in the reagent tube, and the Buffer A reagent is a Buffer solution capable of stabilizing a plasma sample; and a low-temperature ice bag and a second bearing structure for fixing the reagent tube are arranged in the sample storage box.

2. The clinical proteomic plasma sample sampling kit of claim 1, wherein the instruction book storage box, the sample storage box and the reagent tube storage box are detachably connected in sequence.

3. The clinical proteomic plasma sample sampling kit of claim 1, wherein the instruction book storage box, the sample storage box and the reagent tube storage box are stacked in the outer packaging box from top to bottom.

4. The clinical proteomic plasma sample sampling kit of claim 1, wherein the instruction storage box is open at the side and has a card and/or a manual inside.

5. The clinical proteomic plasma sample sampling kit of claim 1, wherein an openable upper cover is disposed on the top of the sample storage box, and the upper cover is connected to the kit through a coded lock.

6. The clinical proteomic plasma sample sampling kit of claim 1, wherein the inner wall of the sample storage box is covered with an insulation layer and a waterproof layer.

7. The clinical proteomic plasma sample sampling kit of claim 1, wherein the sample storage box is provided with a lifting lug on the upper surface.

8. The clinical proteomic plasma sample sampling kit of claim 1, wherein the number of reagent tubes that can be supported in the first support structure and the second support structure is the same.

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