CN214512852U - Device for removing endotoxin in serum - Google Patents
Device for removing endotoxin in serum Download PDFInfo
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- CN214512852U CN214512852U CN202120648149.6U CN202120648149U CN214512852U CN 214512852 U CN214512852 U CN 214512852U CN 202120648149 U CN202120648149 U CN 202120648149U CN 214512852 U CN214512852 U CN 214512852U
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- peristaltic pump
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Abstract
The utility model belongs to the technical field of the bacterin production, especially, get rid of device of endotoxin in serum now proposes following scheme, and it includes the operation panel, two risers that the top fixedly connected with symmetry of operation panel set up, two the equal fixedly connected with in one side that the riser is close to each other fixes the case, two the same U type pipe that is linked together of bottom fixedly connected with of fixed case, the bottom of U type pipe is provided with the play liquid subassembly that is used for the discharge waste liquid, the top of operation panel is provided with the serum collecting box. The utility model discloses simple structure starts first peristaltic pump, through the endotoxin clean up in molecular sieve with the serum, when needs wash U type pipe, rotates the commentaries on classics board, can make to promote two trapezoidal boards of piece promotion and keep away from each other, and then the closing plate plugs up first outlet pipe and removes the closure to the arc venturi tube, starts the second peristaltic pump and opens the water valve, accomplishes the washing to U type pipe, convenient to use.
Description
Technical Field
The utility model relates to a bacterin production technical field especially relates to a get rid of device of endotoxin in serum.
Background
Serum refers to a yellowish transparent liquid separated after the plasma has been coagulated to remove fibrinogen and certain coagulation factors or to plasma from which fibrinogen has been removed. The main functions of the culture medium are to provide basic nutrients, hormones and various growth factors, binding proteins, contact promoters and growth factors to prevent cells from adhering to the wall from mechanical damage and play a certain protection role on the cells in culture, and serum is the most important component of a DMEM cell culture medium for vaccine production.
The serum contains endotoxin, which is not beneficial to cell growth, when the vaccine is produced, the endotoxin in the serum needs to be removed when the serum is extracted, the conventional endotoxin removing device has low removing efficiency and is more tedious, and the device is not convenient to clean after the endotoxin is removed, so the device for removing the endotoxin in the serum is provided, and the problem mentioned above is solved.
Disclosure of Invention
The utility model aims at solving the defects existing in the prior art and providing a device for removing endotoxin in serum.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
a device for removing endotoxin in serum comprises an operation table, wherein the top of the operation table is fixedly connected with two symmetrically arranged vertical plates, one sides of the two vertical plates, which are close to each other, are fixedly connected with fixed boxes, the bottoms of the two fixed boxes are fixedly connected with a same communicated U-shaped pipe, a liquid outlet assembly for discharging waste liquid is arranged at the bottom of the U-shaped pipe, a serum collecting box is arranged at the top of the operation table, the top of the fixed box is fixedly connected with a communicated first water outlet pipe, the first water outlet pipe penetrates through the vertical plates and extends to one side of the vertical plates, a first peristaltic pump is fixedly arranged at the top of the operation table, a serum storing box is arranged below the operation table, a communicated first water inlet pipe is fixedly connected with a water inlet of the first peristaltic pump, the bottom of the first water inlet pipe penetrates through the operation table and extends to the inside of the serum storing box, the water outlet of the first peristaltic pump is communicated with one end of one of the first water outlet pipes, one end of the other first water outlet pipe extends into the serum collecting box, and a cleaning assembly for a cleaning device is arranged at the top of the operating platform.
Preferably, the liquid outlet assembly comprises a drain pipe fixedly connected to the bottom of the U-shaped pipe and communicated with the U-shaped pipe, a plurality of molecular sieves are arranged inside the U-shaped pipe, a water valve is arranged on the drain pipe, a wastewater collection box is arranged at the top of the operating platform, and the bottom of the drain pipe extends into the wastewater collection box.
Preferably, four corners of the bottom of the operating platform are fixedly connected with supporting columns.
Preferably, the cleaning assembly comprises a water tank fixedly connected to the top of the operating platform, a second peristaltic pump is fixedly connected to the top of the water tank, a second water inlet pipe is fixedly connected to the water inlet of the second peristaltic pump and communicated with the water inlet of the second peristaltic pump, the bottom of the second water inlet pipe penetrates through the water tank and extends to the inside of the water tank, a second water outlet pipe is fixedly connected to the water outlet of the second peristaltic pump and communicated with the water outlet of the second peristaltic pump, an arc-shaped pipe is fixedly connected to one end of the second water outlet pipe and communicated with the water outlet of the second peristaltic pump, and the two ends of the arc-shaped pipe are respectively communicated with the tops of the two fixing boxes.
Preferably, the cleaning assembly further comprises the same fixed plate fixedly connected between the two fixed boxes, the screw rod is connected to the inside of the fixed plate in a penetrating mode, the supporting plate is connected to the top of the screw rod in a rotating mode, one side of the two sides of the supporting plate is respectively connected with the two fixed boxes in a sliding mode, the top of the supporting plate is fixedly connected with a pushing block, the inner walls of the two sides of the fixed boxes are slidably connected with the same sealing plate, the sealing plate is close to one side of the pushing block, one end, close to the pushing block, of the transverse rod penetrates through the fixed boxes and is fixedly connected with trapezoidal plates, the trapezoidal plates are far away from the two springs symmetrically arranged on one side of the pushing block, the other ends of the springs are respectively fixedly connected with one sides of the fixed boxes, and the trapezoidal plates are respectively abutted to the two sides of the pushing block.
Preferably, the top of the sealing plate is fixedly connected with a sealing gasket which is in sealing contact with the inner wall of the top of the fixed box.
Preferably, the bottom of the screw is fixedly connected with a rotating plate.
Compared with the prior art, the beneficial effects of the utility model are that:
1. in the utility model, serum in the serum storage box can be transmitted into the first water outlet pipe through the first water inlet pipe by starting the first peristaltic pump, then the serum can enter the fixed box and then be discharged into the U-shaped pipe, endotoxin in the serum can be removed by the molecular sieve, and then the endotoxin in the serum can be continuously removed by transmitting the serum into the serum collection box through the other first water outlet pipe, so that the serum collection can be completed, and the removal efficiency is high;
2. the utility model discloses in, can drive the screw rod through rotating the commentaries on classics board and rotate, the screw rod can drive the backup pad and promote the vertical rebound of piece, promote the piece this moment and can promote two trapezoidal boards and keep away from each other and extrude the spring, and then two trapezoidal boards can seal and drive two horizontal poles and keep away from each other, then can make the horizontal pole drive two closing plates and keep away from each other and plug up first outlet pipe, remove the closure to the arc-shaped pipe simultaneously, then can switch the device into the cleaning mode, through starting the second peristaltic pump and opening the water valve, the second peristaltic pump passes through the arc-shaped pipe with water or other cleaning solution in the water tank and gets into fixed incasement, then can realize washing U type intraduct, and is convenient for wash, the cleaning efficiency is improved, time and labor saving.
The utility model discloses simple structure, through starting endotoxin clean up in first peristaltic pump and molecular sieve with the serum, improved and got rid of efficiency, when needs wash U type pipe, rotate the commentaries on classics board, can make to promote two trapezoidal boards of piece promotion and keep away from each other, and then the closing plate plugs up first outlet pipe and removes the closure to the arc venturi tube, through starting the second peristaltic pump and opening the water valve, accomplishes the washing to U type pipe, convenient to use.
Drawings
FIG. 1 is a schematic structural view of a device for removing endotoxin from serum according to the present invention;
FIG. 2 is a schematic sectional view of the U-shaped tube of the present invention;
FIG. 3 is a schematic sectional view of the fixing box of the present invention;
fig. 4 is a schematic view of the connection of the trapezoidal plate, the pushing block, the cross rod and the sealing plate of the present invention.
In the figure: 1. a serum storage box; 2. a first water inlet pipe; 3. a first peristaltic pump; 4. a first water outlet pipe; 5. a vertical plate; 6. a fixed box; 7. an arc tube; 8. a second water outlet pipe; 9. a second peristaltic pump; 10. a second water inlet pipe; 11. a water tank; 12. a serum collection box; 13. a U-shaped pipe; 14. a water valve; 15. a wastewater collection tank; 16. an operation table; 17. a support pillar; 18. a molecular sieve; 19. a drain pipe; 20. a gasket; 21. a sealing plate; 22. a spring; 23. a trapezoidal plate; 24. a pushing block; 25. a cross bar; 26. rotating the plate; 27. a screw; 28. a fixing plate; 29. and a support plate.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.
Example one
Referring to fig. 1-4, a device for removing endotoxin in serum comprises an operation table 16, wherein four corners of the bottom of the operation table 16 are fixedly connected with supporting columns 17, the top of the operation table 16 is fixedly connected with two vertical plates 5 which are symmetrically arranged, one sides of the two vertical plates 5 which are close to each other are fixedly connected with fixed boxes 6, the bottoms of the two fixed boxes 6 are fixedly connected with a same communicated U-shaped pipe 13, the bottom of the U-shaped pipe 13 is provided with a liquid outlet component for discharging waste liquid, the top of the operation table 16 is provided with a serum collection box 12, the top of the fixed boxes 6 is fixedly connected with a communicated first water outlet pipe 4, the first water outlet pipe 4 penetrates through the vertical plates 5 and extends to one side of the vertical plates 5, the top of the operation table 16 is fixedly provided with a first peristaltic pump 3, a serum storage box 1 is arranged below the operation table 16, and a communicated first water inlet pipe 2 is fixedly connected with a water inlet of the first peristaltic pump 3, the bottom of the first water inlet pipe 2 penetrates through the operating platform 16 and extends to the inside of the serum storage box 1, the water outlet of the first peristaltic pump 3 is communicated with one end of one of the first water outlet pipes 4, one end of the other first water outlet pipe 4 extends to the inside of the serum collection box 12, and the top of the operating platform 16 is provided with a cleaning assembly for a cleaning device.
Example two
The embodiment is improved on the basis of the first embodiment: the liquid outlet assembly comprises a drain pipe 19 fixedly connected to the bottom of the U-shaped pipe 13 and communicated with the U-shaped pipe 13, a plurality of molecular sieves 18 are arranged inside the U-shaped pipe 13, a water valve 14 is arranged on the drain pipe 19, a wastewater collection box 15 is arranged at the top of the operating platform 16, and the bottom of the drain pipe 19 extends into the wastewater collection box 15. In this example, the molecular sieve 18 is an S-100 type molecular sieve.
EXAMPLE III
The embodiment is improved on the basis of the first embodiment: the cleaning assembly comprises a water tank 11 fixedly connected to the top of an operating platform 16, a second peristaltic pump 9 is fixedly connected to the top of the water tank 11, a second water inlet pipe 10 communicated with a water inlet of the second peristaltic pump 9 is fixedly connected to a water inlet of the second peristaltic pump 9, the bottom of the second water inlet pipe 10 penetrates through the water tank 11 and extends into the water tank 11, a second water outlet pipe 8 communicated with a water outlet of the second peristaltic pump 9 is fixedly connected to one end of the second water outlet pipe 8, an arc-shaped pipe 7 communicated with one end of the second water outlet pipe 8 is fixedly connected to one end of the arc-shaped pipe 7, two ends of the arc-shaped pipe 7 are respectively communicated with the tops of the two fixed boxes 6, the cleaning assembly further comprises the same fixed plate 28 fixedly connected between the two fixed boxes 6, a screw 27 is connected to the inner portion of the fixed plate 28 in a penetrating thread manner, a supporting plate 29 is rotatably connected to the tops of the screw 27, two sides of the supporting plate 29 are respectively connected with one side, which is close to the two fixed boxes 6, a pushing block 24 is fixedly connected to the top of the supporting plate 29, fixed 6 both sides inner wall sliding connection of case has same closing plate 21, closing plate 21 is close to one side fixedly connected with horizontal pole 25 that promotes piece 24, horizontal pole 25 is close to the one end that promotes piece 24 and runs through fixed case 6 and fixedly connected with trapezoidal plate 23, trapezoidal plate 23 is kept away from two springs 22 that promote one side fixedly connected with symmetry setting of piece 24, two springs 22's the other end all with one side fixed connection of fixed case 6, two trapezoidal plates 23 respectively with promote the both sides of piece 24 inconsistent, the top fixedly connected with of closing plate 21 and fixed 6 top inner wall sealing contact's of case sealed pad 20, the bottom fixedly connected with of screw rod 27 changes board 26.
The working principle is as follows: when the device is used, the first peristaltic pump 3 is started, the first peristaltic pump 3 transmits serum in the serum storage box 1 into the first water outlet pipe 4 through the first water inlet pipe 2, the serum enters the fixed box 6 and then is discharged into the U-shaped pipe 13, endotoxin in the serum can be removed by the molecular sieve 18 and then is transmitted into the serum collection box 12 through the other first water outlet pipe 4 to be collected, when the U-shaped pipe 13 needs to be cleaned, the rotating plate 26 is rotated, the rotating plate 26 drives the screw 27 to rotate, the screw 27 drives the support plate 29 to vertically move upwards, the support plate 29 drives the pushing block 24 to vertically move upwards, at the moment, the pushing block 24 pushes the two trapezoidal plates 23 to be away from each other and extrude the spring 22, the trapezoidal plates 23 drive the two cross rods 25 to be away from each other, the cross rods 25 drive the two sealing plates 21 to be away from each other and block the first water outlet pipe 4, further, the sealing of the arc-shaped pipe 7 is released, and the second peristaltic pump 9 is started, the water valve 14 is opened, the second peristaltic pump 9 transmits water or other cleaning solution in the water tank 11 to the second water outlet pipe 8 through the second water inlet pipe 10, then the water or other cleaning solution enters the fixed box 6 through the arc-shaped pipe 7, then the inside of the U-shaped pipe 13 is washed, and waste liquid is discharged from the water discharge pipe 19 and enters the waste water collection box 15.
The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.
Claims (7)
1. A device for removing endotoxin in serum comprises an operating platform (16) and is characterized in that the top of the operating platform (16) is fixedly connected with two vertical plates (5) which are symmetrically arranged, one sides of the two vertical plates (5) which are close to each other are fixedly connected with a fixed box (6), the bottoms of the two fixed boxes (6) are fixedly connected with a same communicated U-shaped pipe (13), the bottom of the U-shaped pipe (13) is provided with a liquid outlet component for discharging waste liquid, the top of the operating platform (16) is provided with a serum collection box (12), the top of the fixed box (6) is fixedly connected with a communicated first water outlet pipe (4), the first water outlet pipe (4) penetrates through the vertical plates (5) and extends to one side of the vertical plates (5), the top of the operating platform (16) is fixedly provided with a first peristaltic pump (3), a serum storage box (1) is arranged below the operating platform (16), the utility model discloses a blood serum collection box, including first peristaltic pump (3), the inside of case (1) is deposited to the blood serum, the first inlet tube (2) that the water inlet fixedly connected with of first peristaltic pump (3) is linked together, the bottom of first inlet tube (2) runs through operation panel (16) and extends to the blood serum, the delivery port of first peristaltic pump (3) is linked together with the one end of one of them first outlet pipe (4), another the one end of first outlet pipe (4) extends to the inside of blood serum collection box (12), the top of operation panel (16) is provided with the cleaning assembly who is used for belt cleaning device.
2. The device for removing endotoxin in serum, according to claim 1, wherein the liquid outlet assembly comprises a drain pipe (19) fixedly connected to the bottom of the U-shaped pipe (13) and communicated with the U-shaped pipe (13), a plurality of molecular sieves (18) are arranged inside the U-shaped pipe (13), a water valve (14) is arranged on the drain pipe (19), a wastewater collection box (15) is arranged at the top of the operating platform (16), and the bottom of the drain pipe (19) extends into the wastewater collection box (15).
3. The apparatus for removing endotoxin from serum according to claim 1, wherein support columns (17) are fixedly connected to four corners of the bottom of the operation table (16).
4. The device for removing endotoxin in serum according to claim 1, wherein the cleaning assembly comprises a water tank (11) fixedly connected to the top of the operating platform (16), a second peristaltic pump (9) is fixedly connected to the top of the water tank (11), a second water inlet pipe (10) communicated with a water inlet of the second peristaltic pump (9) is fixedly connected to the water inlet of the second water inlet pipe, the bottom of the second water inlet pipe (10) penetrates through the water tank (11) and extends into the water tank (11), a second water outlet pipe (8) communicated with a water outlet of the second peristaltic pump (9) is fixedly connected to the water outlet of the second water outlet pipe, an arc-shaped pipe (7) communicated with one end of the second water outlet pipe (8) is fixedly connected to one end of the second water outlet pipe, and two ends of the arc-shaped pipe (7) are respectively communicated with the tops of the two fixed boxes (6).
5. The device for removing endotoxin in serum according to claim 1, wherein the cleaning assembly further comprises a same fixing plate (28) fixedly connected between the two fixing boxes (6), a screw rod (27) is connected inside the fixing plate (28) in a penetrating and threaded manner, a supporting plate (29) is rotatably connected to the top of the screw rod (27), two sides of the supporting plate (29) are respectively and slidably connected with one side of the two fixing boxes (6) close to each other, a pushing block (24) is fixedly connected to the top of the supporting plate (29), a same sealing plate (21) is slidably connected to the inner walls of two sides of the fixing boxes (6), a cross rod (25) is fixedly connected to one side of the sealing plate (21) close to the pushing block (24), one end of the cross rod (25) close to the pushing block (24) penetrates through the fixing boxes (6) and is fixedly connected with a trapezoidal plate (23), trapezoidal plate (23) are kept away from two springs (22) that one side fixedly connected with symmetry that promotes piece (24) set up, two the other end of spring (22) all with one side fixed connection of fixed case (6), two trapezoidal plate (23) are inconsistent with the both sides that promote piece (24) respectively.
6. A device for removing endotoxin from serum as claimed in claim 5, wherein a sealing gasket (20) which is in sealing contact with the inner wall of the top of the fixing box (6) is fixedly connected to the top of the sealing plate (21).
7. The device for removing endotoxin from serum according to claim 5, wherein a rotating plate (26) is fixedly connected to the bottom of the screw (27).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120648149.6U CN214512852U (en) | 2021-03-31 | 2021-03-31 | Device for removing endotoxin in serum |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120648149.6U CN214512852U (en) | 2021-03-31 | 2021-03-31 | Device for removing endotoxin in serum |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214512852U true CN214512852U (en) | 2021-10-29 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202120648149.6U Active CN214512852U (en) | 2021-03-31 | 2021-03-31 | Device for removing endotoxin in serum |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214512852U (en) |
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2021
- 2021-03-31 CN CN202120648149.6U patent/CN214512852U/en active Active
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