CN214457874U - Kit for detecting circular RNA in plasma - Google Patents
Kit for detecting circular RNA in plasma Download PDFInfo
- Publication number
- CN214457874U CN214457874U CN202022503206.XU CN202022503206U CN214457874U CN 214457874 U CN214457874 U CN 214457874U CN 202022503206 U CN202022503206 U CN 202022503206U CN 214457874 U CN214457874 U CN 214457874U
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- China
- Prior art keywords
- test tube
- fixed
- kit
- plasma
- box
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 108091028075 Circular RNA Proteins 0.000 title claims description 16
- 238000012360 testing method Methods 0.000 claims abstract description 94
- 238000012545 processing Methods 0.000 claims abstract description 12
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- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims description 9
- 210000002381 plasma Anatomy 0.000 abstract description 16
- 238000001514 detection method Methods 0.000 abstract description 7
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model belongs to the technical field of detection kits, and discloses a kit for detecting cyclic RNA in blood plasma, wherein a test tube bearing box and a processing box are fixed on the upper side of a base, and a cover body is fixed on the upper side of the test tube bearing box through a pin shaft; the test tube containing box is provided with an EP test tube fixing structure, and the right side of the EP test tube fixing structure is provided with an operation flat plate; a PCR test tube fixing structure is arranged on the upper side of the operation flat plate, a test tube flat placing cavity is arranged on the right side of the operation flat plate, and a test tube flat placing rack is fixed in the test tube flat placing cavity; EP test tube fixed knot constructs and PCR test tube fixed knot constructs and is provided with the jack respectively, and the jack upside passes through the spring to be connected with the arc stripper plate, and the arc stripper plate is connected with the stirring piece through removing the frame. The utility model combines the pilot test tube containing box and the processing box, thus improving the efficiency of detecting the annular RNA in the plasma; meanwhile, the test tube is prevented from shaking, and the detection is influenced.
Description
Technical Field
The utility model belongs to the technical field of detect reagent box, especially, relate to a detect cyclic annular RNA's in plasma kit.
Background
At present, the main functions of blood plasma are to carry blood cells, transport substances required for sustaining human life activities, waste products generated in vivo, and the like. Plasma corresponds to the intercellular matrix of connective tissue. Plasma is an important component of blood and is a pale yellow liquid (due to the presence of bilirubin). The chemical components of the plasma comprise 90-92% of water, the other 10% of the water is mainly solute plasma protein, and the plasma contains electrolytes, nutrients (nutrients), enzymes (enzymes), hormones (hormons), cholesterol (cholestrol) and other important components. Plasma proteins are a general term for many proteins and can be classified into three classes, albumin, globulin and fibrinogen by salting out. Plasma contains circular RNA (circRNA), which is a special class of non-coding RNA molecules (sometimes expressed in vivo) and is a recent research hotspot in the RNA field. Unlike traditional linear RNA (containing 5 'and 3' ends), the circRNA molecule is in a closed ring structure, is not influenced by RNA exonuclease, is more stable in expression and is not easy to degrade. Functionally, recent researches show that circRNA molecules are rich in microrna (miRNA) binding sites and play a role of miRNA sponge (miRNA sponge) in cells, so that the inhibition effect of miRNA on target genes of the cells is relieved, and the expression level of the target genes is increased; this mechanism of action is known as the competitive endogenous rna (cerna) mechanism. circRNA plays an important regulatory role in disease through the interaction with disease-associated mirnas. For rapid detection of circular RNA in plasma, the kit plays a critical role. But the test tube fixed orifices for fixed test tube among the current kit, when placing the test tube of different models, because there is the clearance between fixed orifices and the test tube, easily make the test tube produce and rock. Simultaneously current kit can only carry out vertical placing to the test tube, easily makes the inside dust that falls into of test tube.
Through the above analysis, the problems and defects of the prior art are as follows:
(1) be used for the test tube fixed orifices of fixed test tube in the current kit, when placing the test tube of different models, because there is the clearance between fixed orifices and the test tube, easily make the test tube produce and rock.
(2) The existing kit can only vertically place test tubes, so that dust falls into the test tubes easily.
SUMMERY OF THE UTILITY MODEL
In order to solve the problems existing in the prior art, the utility model provides a reagent kit for detecting the circular RNA in the blood plasma.
The utility model is realized in such a way that the reagent kit for detecting the cyclic RNA in the blood plasma is provided with a base; a test tube bearing box and a processing box are fixed on the upper side of the base, and a cover body is fixed on the upper side of the test tube bearing box through a pin shaft;
the test tube containing box is provided with an EP test tube fixing structure, and the right side of the EP test tube fixing structure is provided with an operation flat plate;
a PCR test tube fixing structure is arranged on the upper side of the operation flat plate, a test tube flat placing cavity is arranged on the right side of the operation flat plate, and a test tube flat placing rack is fixed in the test tube flat placing cavity;
EP test tube fixed knot constructs and PCR test tube fixed knot constructs and is provided with the jack respectively, and the jack upside passes through the spring to be connected with the arc stripper plate, and the arc stripper plate is connected with the stirring piece through removing the frame.
Further, handle the case and openly be fixed with the door body through the hinge, handle the case upside and be fixed with display screen and keyboard.
Furthermore, a network connection device is arranged inside the processing box.
Further, the test tube frame of keeping flat is provided with the framework, and the framework is provided with the recess of keeping flat.
Further, the framework lower extreme is provided with electric telescopic handle and connects, and electric telescopic handle is connected with the fixed disk.
Furthermore, the test tube containing box is provided with a groove on the side face, a coiled pipe is fixed on the groove through a fixing bolt, and a lighting lamp is fixed at the end part of the coiled pipe.
Combine foretell all technical scheme, the utility model discloses the advantage that possesses and positive effect are:
the utility model discloses pilot scale tube holds dress box and handles the case and makes up the use, has improved the efficiency that cyclic annular RNA detected in the plasma. Meanwhile, when a test tube needs to be placed, the shifting block is buckled to move outwards along the slide way, so that the distance between the arc-shaped extrusion plates is increased, and the test tube is placed; loosen slowly and dial the movable block, utilize the restoring force of spring, the arc stripper plate extrudees fixedly to the test tube, prevents that the test tube from rocking, influences going on that detects.
The utility model discloses well processing case openly is fixed with a body through the hinge, and processing case upside is fixed with display screen and keyboard, realizes the corresponding operation of data.
The utility model discloses well processing incasement portion is provided with the internet access equipment, realizes the transmission of information.
The utility model discloses well test tube is kept flat and is set up the framework, and the framework is provided with the recess of keeping flat for place the test tube, avoid the inside dust that falls into of test tube.
The utility model discloses well framework lower extreme is provided with electric telescopic handle and connects, and electric telescopic handle is connected with the fixed disk, realizes the lift of framework, conveniently places the test tube.
The utility model discloses a setting of coiled pipe can be as required, and the position of adjustment light avoids the light dark, influences the detection operation.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed to be used in the embodiments of the present application will be briefly described below, and it is obvious that the drawings described below are only some embodiments of the present application, and it is obvious for those skilled in the art that other drawings can be obtained from the drawings without creative efforts.
FIG. 1 is a schematic structural diagram of a kit for detecting circular RNA in plasma according to an embodiment of the present invention.
Fig. 2 is a schematic structural view of a test tube containing box provided by the embodiment of the present invention.
Fig. 3 is a structural schematic view of a test tube flat placing rack provided by the embodiment of the present invention.
FIG. 4 is a schematic view of an EP tube fixing structure and a PCR tube fixing structure provided by the embodiment of the present invention.
Fig. 5 is a schematic view of an installation structure of an illumination lamp provided by an embodiment of the present invention.
In the figure: 1. a cover body; 2. packing the test tubes into a box; 3. a base; 4. a door body; 5. a keyboard; 6. a display screen; 7. an EP test tube fixing structure; 8. a PCR test tube fixing structure; 9. a test tube flat placing cavity; 10. placing the test tube on a rack; 11. operating the flat plate; 12. a frame body; 13. horizontally placing the groove; 14. an electric telescopic rod; 15. fixing the disc; 16. a shifting block; 17. an arc-shaped extrusion plate; 18. a spring; 19. a jack; 20. an arc-shaped base; 21. a movable frame; 22. fixing the bolt; 23. a groove; 24. a serpentine tube; 25. an illuminating lamp.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
To solve the problems existing in the prior art, the utility model provides a reagent kit for detecting cyclic RNA in blood plasma, which is described in detail with reference to the attached drawings.
As shown in fig. 1, in order to process and transmit data at any time. The utility model is provided with a test tube containing box 2 and a processing box which are fixed on the upper side of a base 3; the utility model discloses 2 upsides of test tube bearing box have lid 1 through the round pin hub fixation. Simultaneously the utility model discloses it openly is fixed with a body 4 through the hinge to handle the case, handles the case upside and is fixed with display screen 6 and keyboard 5. Wherein, the inside network connection equipment that is provided with of processing case, like router etc..
As shown in fig. 2, for organized placement of the tubes. The utility model discloses holding the box at the test tube and being provided with EP test tube fixed knot and construct 7, EP test tube fixed knot constructs 7 right sides and is provided with the operation flat board 11, and operation flat board 11 upside is provided with PCR test tube fixed knot and constructs 8. Wherein, the operation flat plate 11 right side is provided with the test tube chamber 9 of keeping flat, and test tube chamber 9 of keeping flat is fixed with test tube frame 10 of keeping flat.
As shown in fig. 3, the test tube is laid flat for convenience; the test tube flat placing frame of the utility model is provided with a frame body 12, the frame body 12 is provided with a flat placing groove 13 for placing the test tube; in order to realize the lift of the test tube frame of keeping flat, the utility model discloses well framework 12 lower extreme is provided with electric telescopic handle 14 and connects, and electric telescopic handle 14 is connected with fixed disk 15. When taking and placing the test tube, the electric telescopic rod 14 adjusts the height of the frame body 12.
As shown in fig. 4, the test tube is prevented from shaking, which affects the detection. In the utility model, the EP test tube fixing structure and the PCR test tube fixing structure 8 are respectively provided with a jack 19, the upper side of the jack 19 is connected with an arc-shaped extrusion plate 17 through a spring 18, and the arc-shaped extrusion plate 17 is connected with a shifting block 16 through a moving frame 21; when a test tube needs to be placed, the shifting block 16 is buckled to move outwards along the slide way, the distance between the arc-shaped extrusion plates 17 is driven to be increased, and the test tube is placed; the shifting block 16 is slowly released, and the arc-shaped extrusion plate 17 extrudes and fixes the test tube by utilizing the restoring force of the spring.
As shown in fig. 5, in order to avoid darkness, the detection operation is affected. The side surface of the test tube containing box is provided with a groove 23, the groove 23 is fixed with a coiled tube 24 through a fixing bolt 22, and the end part of the coiled tube 24 is fixed with a lighting lamp 25; the position of the illumination lamp 25 can be adjusted as necessary by providing the serpentine tube 24.
The utility model discloses a theory of operation does: the utility model discloses it is provided with EP test tube fixed knot to construct 7 and PCR test tube fixed knot constructs 8 and fixes corresponding reagent pipe respectively to hold the box at the test tube. In the operation plate 11, the test tube placing chamber 9 is fixed with the test tube placing rack 10. The utility model discloses a handle the case and handle case upside and be fixed with display screen 6 and keyboard 5, handle incasement portion and be provided with network connection equipment, carry out the processing and the transmission of data at any time. Through the setting of coiled pipe 24, can be as required, the position of adjustment light 25 avoids light dark, influences the detection operation.
The above description is only for the preferred specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art should be covered by the protection scope of the present invention within the technical scope of the present invention, any modification, equivalent replacement, and improvement made within the spirit and principle of the present invention.
Claims (6)
1. A kit for detecting circular RNA in plasma is characterized in that the kit for detecting the circular RNA in the plasma is provided with:
a base;
a test tube bearing box and a processing box are fixed on the upper side of the base, and a cover body is fixed on the upper side of the test tube bearing box through a pin shaft;
the test tube containing box is provided with an EP test tube fixing structure, and the right side of the EP test tube fixing structure is provided with an operation flat plate;
a PCR test tube fixing structure is arranged on the upper side of the operation flat plate, a test tube flat placing cavity is arranged on the right side of the operation flat plate, and a test tube flat placing rack is fixed in the test tube flat placing cavity;
EP test tube fixed knot constructs and PCR test tube fixed knot constructs and is provided with the jack respectively, and the jack upside passes through the spring to be connected with the arc stripper plate, and the arc stripper plate is connected with the stirring piece through removing the frame.
2. The kit for detecting the cyclic RNA in the plasma according to claim 1, wherein a door body is fixed on the front surface of the treatment box through a hinge, and a display screen and a keyboard are fixed on the upper side of the treatment box.
3. The kit for detecting circular RNA in plasma according to claim 1, wherein a network connection device is arranged inside the processing box.
4. The kit for detecting circular RNA in plasma according to claim 1, wherein the horizontal frame of the test tube is provided with a frame body, and the frame body is provided with a horizontal groove.
5. The kit for detecting circular RNA in plasma according to claim 4, wherein the lower end of the frame is connected with an electric telescopic rod, and the electric telescopic rod is connected with a fixed disk.
6. The kit for detecting circular RNA in plasma according to claim 1, wherein the test tube housing case is provided with a groove on the side thereof, a coil tube is fixed to the groove by a fixing bolt, and an illuminating lamp is fixed to the end of the coil tube.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022503206.XU CN214457874U (en) | 2020-11-03 | 2020-11-03 | Kit for detecting circular RNA in plasma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022503206.XU CN214457874U (en) | 2020-11-03 | 2020-11-03 | Kit for detecting circular RNA in plasma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214457874U true CN214457874U (en) | 2021-10-22 |
Family
ID=78148693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022503206.XU Expired - Fee Related CN214457874U (en) | 2020-11-03 | 2020-11-03 | Kit for detecting circular RNA in plasma |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214457874U (en) |
-
2020
- 2020-11-03 CN CN202022503206.XU patent/CN214457874U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20211022 |