CN214400493U - Pet treatment antibody preparation culture apparatus - Google Patents
Pet treatment antibody preparation culture apparatus Download PDFInfo
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- CN214400493U CN214400493U CN202023011767.4U CN202023011767U CN214400493U CN 214400493 U CN214400493 U CN 214400493U CN 202023011767 U CN202023011767 U CN 202023011767U CN 214400493 U CN214400493 U CN 214400493U
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Abstract
The utility model discloses a preparation and culture device for pet therapeutic antibodies, which comprises a disinfection device and a stirring device; a culture tank and a collection device; the culture tank comprises a tank body, a tank cover, a silica gel pad, a locking buckle, a filtering component, a silica gel plug and an auxiliary liquid pipe; the stirring device is arranged inside the culture tank; the collecting device is arranged at the bottom of the culture tank; can provide good sterile environment for the reproduction of antibody culture cells to the bottom is provided with filter equipment and can filters the necrotic cell, guarantees the purity of antibody extraction stoste.
Description
Technical Field
The utility model relates to an antibody culture technical field especially relates to a pet treatment antibody preparation culture apparatus.
Background
Antibodies are proteins that are produced by the body as a result of stimulation by antigens and have a protective effect. It (immunoglobulin is not just an antibody) is a large Y-shaped protein secreted by plasma cells (effector B cells), used by the immune system to identify and neutralize foreign substances such as bacteria, viruses, etc., and found only in body fluids such as blood of vertebrates, and the cell membrane surface of B cells thereof. Antibodies recognize a unique feature of a particular foreign object, referred to as an antigen. Antibodies are widely used in medical practice. For example, the compound has certain effects on the prevention, diagnosis and treatment of diseases.
In the existing experiment for culturing the antibody, a method for manually feeding a culture solution is adopted, and the method has the defects of uneven feeding of the nutrient solution, easy pollution to the culture environment, repeated introduction and export and difficulty in ensuring the invasion of external bacteria.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a pet treatment antibody preparation culture apparatus to solve the problem that above-mentioned prior art exists, can realize that culture solution and additive can add under the aseptic condition of assurance, cultivate the purpose that the result can direct filtration derive, pollution abatement.
In order to achieve the above object, the utility model provides a following scheme:
the utility model provides a pet treatment antibody preparation culture device, which comprises a culture solution and a culture device for culturing an antibody by using the culture solution, wherein the culture device comprises a disinfection device and a stirring device; a culture tank and a collection device; the disinfection device is arranged above the culture tank; the stirring device is arranged inside the culture tank; the collecting device is arranged at the bottom of the culture tank;
the culture tank is of a cylindrical structure and comprises a tank body, a tank cover, a silica gel pad, a locking buckle, a filtering assembly, a silica gel plug and an auxiliary liquid pipe; one side of the tank cover is hinged with the tank body, and the other side of the tank cover is detachably connected with the tank body through a locking buckle; the bottom surface of the tank cover is bonded with the top surface of the silica gel pad; the bottom surface of the silica gel pad is in contact with the top surface of the tank body; the middle part of the side wall of the tank body is provided with an auxiliary liquid hole; one end of the auxiliary liquid pipe is communicated with the tank body through the auxiliary liquid hole; the silica gel plug is matched with the inner diameter of the auxiliary liquid pipe and arranged at the other end of the auxiliary liquid pipe;
the outer diameter of the filter assembly is matched with the inner diameter of the tank body; the filter assembly is arranged on the bottom surface of the tank body; the bottom surface of the tank body is provided with a liquid collecting hole, and the collecting device is communicated with the tank body through the liquid collecting hole.
Preferably, assist the liquid pipe with the jar side wall is linked together and the other end is provided with the silica gel stopper, has realized that external addition part adds the medicament and can puncture through instruments such as needle tubing and push, has avoided opening the condition that the contaminated culture solution appears in the cover.
Preferably, the silica gel pad bonds in the cover bottom surface, has realized the cover lock back, and the cover can keep sealed with the jar body, avoids the outside air to get into and leads to the pollution.
The filter assembly comprises a filter plate and a silica gel ring; the circumferential side surface of the filter plate is provided with a sealing groove; the silica gel circle is filled in the seal groove, the side of the silica gel circle is in transition fit with the inner wall of the tank body.
Preferably, the sealing groove is formed in the circumferential side face of the filter plate, the silica gel ring is filled in the sealing groove, the filter plate can be regulated to a certain degree in the tank body, the culture solution can be filtered, necrotic cells are removed, and the purification steps of extracting the original solution of the antibody are reduced.
The stirring device comprises a motor, a stirring shaft and a stirring rod; the motor is fixedly arranged at the center of the top surface of the tank cover; one end of the stirring shaft penetrates through the center of the top surface of the tank cover and is in transmission connection with the motor output shaft; the other end of the stirring shaft is fixedly connected to the middle part of the stirring rod; the stirring rod is arranged above the filter plate.
Preferably, (mixing) shaft and motor output shaft pass through the fixed pin and realize dismantling the transmission and be connected, can not be when the cover is opened promptly, and the puddler does not take place to interfere with the jar body, can realize the stirring to the culture solution again when the cover is closed, simultaneously, can dismantle and to make the washing of spare part clean more convenient.
The disinfection device comprises a main input pipe, a disinfection pipe and a main output pipe; the top surface of the tank cover is provided with two through holes which are an air outlet hole and an air inlet hole respectively; one end of the main output pipe is communicated with the tank cover through the air outlet hole; the other end is communicated with one end of the disinfection tube; the other end of the disinfection pipe is communicated with one end of the main input pipe; the other end of the main input pipe is communicated with the tank cover through the air inlet hole.
Preferably, the disinfection device can treat the gas in the tank body to avoid the culture solution from being polluted, and the treated air returns to the tank body to form circulation.
A plurality of disinfection tubes are arranged; the disinfection tube comprises a tube body and a disinfection lamp; the sterilizing lamp is fixedly arranged on the inner wall of the tube body.
Preferably, the disinfection lamp is arranged in the disinfection tube, so that the influence of the disinfection lamp on microorganisms in the culture solution is avoided.
The collecting device comprises a liquid collecting pipe and a liquid collecting valve; one end of the liquid collecting pipe is communicated with the tank body through the liquid collecting hole; the liquid collecting valve is arranged on the liquid collecting pipe.
Preferably, the liquid collecting valve controls the liquid collecting pipe, so that the antibody extraction stock solution is rapidly and aseptically led out after leaking to the bottom of the tank body.
The filter assembly further comprises an extraction rod; the two extraction rods are arranged and are fixedly arranged on the top surface of the filter plate symmetrically about the center of the filter plate; the top end of the extraction rod is lower than the top surface of the tank body, and the side surface of the top end of the extraction rod is provided with an extraction hole.
The stirring rod is parallel to the top surface of the filter plate, the distance between the stirring rod and the top surface of the filter plate is 5mm-20mm, and the stirring rod and the extraction rod do not interfere with each other.
The disinfection device also comprises an air supply pipe, an air supply valve, an air exchange pipe, an air exchange valve and an axial flow machine; the air supplementing valve is arranged on the air supplementing pipe; one end of the air supplementing pipe penetrates through the side wall of the main input pipe and is communicated with the main input pipe, and the other end of the air supplementing pipe is communicated with the outside; the air exchange valve is arranged on an air exchange pipe, one end of the air exchange pipe penetrates through the side wall of the main output pipe and is communicated with the main output pipe, and the other end of the air exchange pipe is communicated with the outside; the axial flow machine is arranged in the main input pipe.
Preferably, the rapid circular sterilization of the gas in the sterilization device can be rapidly realized by adding the axial flow machine, the air flowing speed is increased, and the sterilization efficiency is improved.
Preferably, the air supply pipe and the air supply valve are arranged, so that the air in the tank body is supplied, and the tank body is disinfected by the disinfection pipe in order to avoid external pollution.
Preferably, a ventilation valve and a ventilation pipe are arranged, so that the dirty gas in the tank body is updated, and the death of organisms in the culture solution is avoided.
The utility model discloses a following technological effect:
1. the utility model discloses a quick circulation of culture tank is disinfected, has avoided the rotten of culture solution among the culture process.
2. The utility model discloses an supplementary not opening jar of adding medicament adds, has reduced the link that can cause the pollution, has improved cultivation efficiency.
3. The utility model discloses can supply fresh air in the experiment is gone on, and can not cause the pollution of culture solution, optimize the cultivation environment.
4. The utility model discloses set up bottom liquid collecting device, reduced the antibody and drawn the probability that receives the pollution of stoste.
5. The utility model discloses the filtration purification of culture solution has been realized in the addition of filter plate, has reduced traditional link of leading-in derivation repeatedly, has improved cultivation efficiency.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without inventive labor.
FIG. 1 is a front view of the present invention
The device comprises a tank body-11, a tank cover-12, a silica gel pad-13, a locking buckle-14, a filtering component-15, a filtering plate-151, a silica gel ring-152, an extraction rod-153, a silica gel plug-16, an auxiliary liquid pipe-17, a motor-21, a stirring shaft-22, a stirring rod-23, a total input pipe-31, a disinfection pipe-32, a pipe body-321, a disinfection lamp-322, a total output pipe-33, an air supply pipe-34, an air supply valve-35, an air exchange pipe-36, an air exchange valve-37, a liquid collection pipe-41 and a liquid collection valve-42.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In order to make the above objects, features and advantages of the present invention more comprehensible, the present invention is described in detail with reference to the accompanying drawings and the detailed description.
The utility model provides a pet therapeutic antibody preparation and culture device, which comprises a culture solution and a culture device for culturing an antibody by using the culture solution, wherein the culture device comprises a disinfection device and a stirring device; a culture tank and a collection device; the disinfection device is arranged above the culture tank; the stirring device is arranged inside the culture tank; the collecting device is arranged at the bottom of the culture tank;
the culture tank is of a cylindrical structure and comprises a tank body 11, a tank cover 12, a silica gel pad 13, a locking buckle 14, a filtering component 15, a silica gel plug 16 and an auxiliary liquid pipe 17; one side of the tank cover 12 is hinged with the tank body 11, and the other side is detachably connected with the tank body 11 through a locking buckle 14; the bottom surface of the pot cover 12 is bonded with the top surface of the silica gel pad 13; the bottom surface of the silica gel pad 13 is contacted with the top surface of the tank body 11; the middle part of the side wall of the tank body 11 is provided with an auxiliary liquid hole; one end of the auxiliary liquid pipe 17 is communicated with the tank body 11 through an auxiliary liquid hole; the silica gel plug 16 is matched with the inner diameter of the auxiliary liquid pipe 17, and the silica gel plug 16 is arranged at the other end of the auxiliary liquid pipe 17;
the outer diameter of the filter assembly 15 is matched with the inner diameter of the tank body 11; the filtering component 15 is arranged on the bottom surface of the tank body 11; the bottom surface of the tank body 11 is provided with a liquid collecting hole, and the collecting device is communicated with the tank body 11 through the liquid collecting hole.
The filter assembly 15 comprises a filter plate 151 and a silicone ring 152; a sealing groove is formed in the circumferential side surface of the filter plate 151; the silica gel ring 152 is filled in the sealing groove, and the side surface of the silica gel ring 152 is in transition fit with the inner wall of the tank body 11.
The stirring device comprises a motor 21, a stirring shaft 22 and a stirring rod 23; the motor 21 is fixedly arranged at the center of the top surface of the tank cover 12; one end of the stirring shaft 22 penetrates through the center of the top surface of the tank cover 12 and is in transmission connection with an output shaft of the motor 21; the other end of the stirring shaft 22 is fixedly connected with the middle part of the stirring rod 23; the stirring rod 23 is provided above the filter sheet 151.
The disinfection device comprises a main input pipe 31, a disinfection pipe 32 and a main output pipe 33; the top surface of the tank cover 12 is provided with two through holes which are an air outlet hole and an air inlet hole respectively; one end of the main output pipe 33 is communicated with the tank cover 12 through an air outlet hole; the other end is communicated with one end of the disinfection tube 32; the other end of the disinfection tube 32 is communicated with one end of the main input tube 31; the other end of the main input pipe 31 is communicated with the tank cover 12 through an air inlet hole.
A plurality of disinfection tubes 32 are arranged; the sterilizing tube 32 includes a tube body 321 and a sterilizing lamp 322; the sterilizing lamp 322 is fixedly installed on the inner wall of the tube 321.
The collecting device comprises a collecting pipe 41 and a collecting valve 42; one end of the liquid collecting pipe 41 is communicated with the tank body 11 through a liquid collecting hole; the header valve 42 is provided on the header pipe 41.
The filter assembly 15 further comprises an extraction rod 153; two extraction rods 153 are arranged and are fixedly mounted on the top surface of the filter plate 151 in a central symmetry manner about the filter plate 151; the top end of the extraction rod 153 is lower than the top surface of the tank body 11, and the side surface of the top end of the extraction rod 153 is provided with an extraction hole.
The stirring rod 23 is parallel to the top surface of the filter plate 151, the distance between the stirring rod 23 and the top surface of the filter plate 151 is 5mm-20mm, and the stirring rod 23 and the extraction rod 153 do not interfere with each other.
The disinfection device also comprises an air supply pipe 34, an air supply valve 35, a ventilation pipe 36, a ventilation valve 37 and an axial flow machine 38; the air supplementing valve 35 is arranged on the air supplementing pipe 34; one end of the air supply pipe 34 penetrates through the side wall of the main input pipe 31 and is communicated with the main input pipe 31, and the other end of the air supply pipe is communicated with the outside; the scavenging valve 37 is arranged on the scavenging pipe 36, one end of the scavenging pipe 36 penetrates through the side wall of the total output pipe 33 and is communicated with the total output pipe 33, and the other end of the scavenging pipe is communicated with the outside; an axial flow machine 38 is arranged in the main inlet pipe 31.
The utility model discloses a following technological effect:
1. the utility model discloses a quick circulation of culture tank is disinfected, has avoided the rotten of culture solution among the culture process.
2. The utility model discloses an supplementary not opening jar of adding medicament adds, has reduced the link that can cause the pollution, has improved cultivation efficiency.
3. The utility model discloses can supply fresh air in the experiment is gone on, and can not cause the pollution of culture solution, optimize the cultivation environment.
4. The utility model discloses set up bottom liquid collecting device, reduced the antibody and drawn the probability that receives the pollution of stoste.
5. The utility model discloses the filtration purification of culture solution has been realized in the addition of filter plate, has reduced traditional link of leading-in derivation repeatedly, has improved cultivation efficiency.
In the description of the present invention, it is to be understood that the terms "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on those shown in the drawings, and are merely for convenience of description of the present invention, and do not indicate or imply that the device or element so referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.
The above-mentioned embodiments are only intended to describe the preferred embodiments of the present invention, but not to limit the scope of the present invention, and those skilled in the art should also be able to make various modifications and improvements to the technical solution of the present invention without departing from the spirit of the present invention, and all such modifications and improvements are intended to fall within the scope of the present invention as defined in the appended claims.
Claims (9)
1. The utility model provides a pet treatment antibody preparation culture apparatus, includes culture solution and utilizes the culture solution to cultivate the culture apparatus of antibody which characterized in that: the culture device comprises a disinfection device and a stirring device; a culture tank and a collection device; the disinfection device is arranged above the culture tank; the stirring device is arranged inside the culture tank; the collecting device is arranged at the bottom of the culture tank;
the culture tank is of a cylindrical structure and comprises a tank body (11), a tank cover (12), a silica gel pad (13), a locking buckle (14), a filtering component (15), a silica gel plug (16) and an auxiliary liquid pipe (17); one side of the tank cover (12) is hinged with the tank body (11), and the other side of the tank cover is detachably connected with the tank body (11) through a locking buckle (14); the bottom surface of the pot cover (12) is bonded with the top surface of the silica gel pad (13); the bottom surface of the silica gel pad (13) is in contact with the top surface of the tank body (11); the middle part of the side wall of the tank body (11) is provided with an auxiliary liquid hole; one end of the auxiliary liquid pipe (17) is communicated with the tank body (11) through the auxiliary liquid hole; the silica gel plug (16) is matched with the inner diameter of the auxiliary liquid pipe (17), and the silica gel plug (16) is arranged at the other end of the auxiliary liquid pipe (17);
the outer diameter of the filter assembly (15) is matched with the inner diameter of the tank body (11); the filtering component (15) is arranged on the bottom surface of the tank body (11); the bottom surface of the tank body (11) is provided with a liquid collecting hole, and the collecting device is communicated with the tank body (11) through the liquid collecting hole.
2. The pet therapeutic antibody preparation culture device of claim 1, wherein: the filter assembly (15) comprises a filter plate (151) and a silica gel ring (152); the circumferential side surface of the filter plate (151) is provided with a sealing groove; the silica gel circle (152) is filled in the sealing groove, and the side surface of the silica gel circle (152) is in transition fit with the inner wall of the tank body (11).
3. The pet therapeutic antibody preparation culture device according to claim 2, characterized in that: the stirring device comprises a motor (21), a stirring shaft (22) and a stirring rod (23); the motor (21) is fixedly arranged at the center of the top surface of the tank cover (12); one end of the stirring shaft (22) penetrates through the center of the top surface of the tank cover (12) and is in transmission connection with an output shaft of the motor (21); the other end of the stirring shaft (22) is fixedly connected to the middle part of the stirring rod (23); the stirring rod (23) is arranged above the filter plate (151).
4. The pet therapeutic antibody preparation culture device of claim 1, wherein: the disinfection device comprises a main input pipe (31), a disinfection pipe (32) and a main output pipe (33); the top surface of the tank cover (12) is provided with two through holes which are respectively an air outlet hole and an air inlet hole; one end of the main output pipe (33) is communicated with the tank cover (12) through the air outlet hole; the other end is communicated with one end of the disinfection tube (32); the other end of the disinfection pipe (32) is communicated with one end of the main input pipe (31); the other end of the main input pipe (31) is communicated with the tank cover (12) through the air inlet hole.
5. The pet therapeutic antibody preparation culture device of claim 4, wherein: a plurality of disinfection tubes (32) are arranged; the disinfection tube (32) comprises a tube body (321) and a disinfection lamp (322); the disinfection lamp (322) is fixedly arranged on the inner wall of the pipe body (321).
6. The pet therapeutic antibody preparation culture device of claim 1, wherein: the collecting device comprises a liquid collecting pipe (41) and a liquid collecting valve (42); one end of the liquid collecting pipe (41) is communicated with the tank body (11) through the liquid collecting hole; the liquid collecting valve (42) is arranged on the liquid collecting pipe (41).
7. The pet therapeutic antibody preparation culture device of claim 3, wherein: the filter assembly (15) further comprises an extraction rod (153); the two extraction rods (153) are arranged and are fixedly mounted on the top surface of the filter plate (151) symmetrically with respect to the center of the filter plate (151); the top end of the extraction rod (153) is lower than the top surface of the tank body (11), and the side surface of the top end of the extraction rod (153) is provided with an extraction hole.
8. The pet therapeutic antibody preparation culture device of claim 7, wherein: the stirring rod (23) is parallel to the top surface of the filter plate (151), the distance between the stirring rod (23) and the top surface of the filter plate (151) is 5mm-20mm, and the stirring rod (23) and the extraction rod (153) do not interfere with each other.
9. The pet therapeutic antibody preparation culture device of claim 4, wherein: the disinfection device also comprises an air supply pipe (34), an air supply valve (35), a ventilation pipe (36), a ventilation valve (37) and an axial flow machine (38); the air supplementing valve (35) is arranged on the air supplementing pipe (34); one end of the air supply pipe (34) penetrates through the side wall of the main input pipe (31) and is communicated with the main input pipe (31), and the other end of the air supply pipe is communicated with the outside; the air exchanging valve (37) is arranged on an air exchanging pipe (36), one end of the air exchanging pipe (36) penetrates through the side wall of the total output pipe (33) and is communicated with the total output pipe (33), and the other end of the air exchanging pipe is communicated with the outside; the axial flow machine (38) is arranged in the main input pipe (31).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202023011767.4U CN214400493U (en) | 2020-12-15 | 2020-12-15 | Pet treatment antibody preparation culture apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202023011767.4U CN214400493U (en) | 2020-12-15 | 2020-12-15 | Pet treatment antibody preparation culture apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214400493U true CN214400493U (en) | 2021-10-15 |
Family
ID=78038186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202023011767.4U Active CN214400493U (en) | 2020-12-15 | 2020-12-15 | Pet treatment antibody preparation culture apparatus |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214400493U (en) |
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2020
- 2020-12-15 CN CN202023011767.4U patent/CN214400493U/en active Active
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